Abstract: An axle-mounted sensor cuff is configured to be removably attachable to a hub portion of a railcar wheel of a railcar wheelset for use in determining anomalies associated with the railcar wheel, or a railcar bogie assembly that the railcar wheelset is part of, or a track, during motion of the railcar wheelset on a track. The sensor cuff includes one or more sensors, such as inertial measurement units (IMU's), mounted thereto to measure parameters that are used for determining the anomalies during motion of the railcar wheel on the track. In addition, a wheel-mounted sensor ring is configured to be removably attachable to a hub portion of a railcar wheel of a railcar wheelset for use in determining anomalies associated with the railcar wheel, or a railcar bogie assembly that the railcar wheelset is part of, or a track, during motion of the railcar wheelset on a track.

Abstract: A method that includes operating a bus monitoring system having at least one interface configured to be coupled to at least one communication bus and receive bus traffic transmitted over the communication bus(es). The method also includes, using a device authentication system of the bus monitoring system, analyzing the bus traffic received via the at least one interface. Analyzing the bus traffic includes obtaining a message in the bus traffic (where the message identifies a source), identifying a support vector machine that corresponds to the source of the message, applying a wave transform to a waveform of the received message in order to generate a transformed waveform, inputting the transformed waveform to the identified support vector machine, and taking action in response to the identified support vector machine determining that the transformed waveform or the associated information does not correspond to the source.

Abstract: A process detects anomalies on a controller area network (CAN) bus. An arbitration field in a message on the CAN bus is analyzed, and a data field in the message on the CAN bus is inspected. The process further monitors a frequency of message identifiers that are transmitted across the CAN bus, and determines that an overall bus load crosses a threshold. The process then transmits an alert when the analyzing the arbitration field, the inspecting the data field, the monitoring the frequency, and the determining the overall bus load indicate that an anomaly has occurred on the CAN bus.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?) and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: A process detects anomalies on a controller area network (CAN) bus. An arbitration field in a message on the CAN bus is analyzed, and a data field in the message on the CAN bus is inspected. The process further monitors a frequency of message identifiers that are transmitted across the CAN bus, and determines that an overall bus load crosses a threshold. The process then transmits an alert when the analyzing the arbitration field, the inspecting the data field, the monitoring the frequency, and the determining the overall bus load indicate that an anomaly has occurred on the CAN bus.

Abstract: A method that includes operating a bus monitoring system having at least one interface configured to be coupled to at least one communication bus and receive bus traffic transmitted over the communication bus(es). The method also includes, using a device authentication system of the bus monitoring system, analyzing the bus traffic received via the at least one interface. Analyzing the bus traffic includes obtaining a message in the bus traffic (where the message identifies a source), identifying a support vector machine that corresponds to the source of the message, applying a wave transform to a waveform of the received message in order to generate a transformed waveform, inputting the transformed waveform to the identified support vector machine, and taking action in response to the identified support vector machine determining that the transformed waveform or the associated information does not correspond to the source.

Abstract: A fuel injector is provided that includes various precise configuration parameters, including dimensions, shape and/or relative positioning of fuel injector features, resulting in improved efficiency of fuel flow through the fuel injector.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?) and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: A fluid injector assembly extending along a longitudinal axis comprising a housing, and an injector positioned within the housing, the injector comprising a injector body having an interior cavity, a plunger positioned within the interior cavity and comprising a plunger body, a fluid delivery passage along at least a portion of the plunger body, and a plunger tip positioned at a downstream end of the plunger body, the fluid delivery passage comprising a longitudinal passage and at least one internal swirl passage, and the internal swirl passage being angled relative to the longitudinal axis and extending from the longitudinal passage to an opening upstream of the plunger tip, and a nozzle positioned at a downstream end of the injector body and including at least one nozzle passage, fluid being delivered from an upstream end of the injector to the at least one nozzle passage through the fluid delivery passage.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: An injector combustion shield assembly comprising a bore configured to receive a fuel injector, the bore including a fluid opening in fluid communication with a fluid jacket and a fluid outlet positioned within an annular wall of the bore; and a valve positioned between the fluid jacket and the fluid opening and configured to selectively permit a fluid from the fluid jacket to enter the bore, the valve being movable between an open configuration to permit fluid flow from the fluid jacket into the bore via the fluid opening and a closed configuration to prevent fluid flow from the fluid jacket into the bore.

Abstract: A fluid injector assembly extending along a longitudinal axis comprising a housing, and an injector positioned within the housing, the injector comprising a injector body having an interior cavity, a plunger positioned within the interior cavity and comprising a plunger body, a fluid delivery passage along at least a portion of the plunger body, and a plunger tip positioned at a downstream end of the plunger body, the fluid delivery passage comprising a longitudinal passage and at least one internal swirl passage, and the internal swirl passage being angled relative to the longitudinal axis and extending from the longitudinal passage to an opening upstream of the plunger tip, and a nozzle positioned at a downstream end of the injector body and including at least one nozzle passage, fluid being delivered from an upstream end of the injector to the at least one nozzle passage through the fluid delivery passage.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: An organism development system includes: at least one neuromorphic device including multiple sets of hardware components that each store one or parameters of neuromorphic configuration data to implement a neuron of a neural network, wherein: the neural network is configured by neuromorphic configuration data to derive a proposed genome or epigenome of a new organism meant to have a sought-for trait, and the neuromorphic configuration data is generated by training the neural network with a usage data set that includes trait data indicative of a trait and biological data indicative of a genome for each of multiple organisms; a genome or epigenome printing device to print genetic/epigenetic material of the new organism based on the proposed genome or epigenome, respectively; and a trait detection device to detect an observed trait of the new organism following its at least its generation for incorporation back into the usage data set.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind. Transforming Growth Factor beta (TGF?), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralize TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: An organism development system includes: at least one neuromorphic device including multiple sets of hardware components that each store one or parameters of neuromorphic configuration data to implement a neuron of a neural network, wherein: the neural network is configured by neuromorphic configuration data to derive a proposed genome or epigenome of a new organism meant to have a sought-for trait, and the neuromorphic configuration data is generated by training the neural network with a usage data set that includes trait data indicative of a trait and biological data indicative of a genome for each of multiple organisms; a genome or epigenome printing device to print genetic/epigenetic material of the new organism based on the proposed genome or epigenome, respectively; and a trait detection device to detect an observed trait of the new organism following its at least its generation for incorporation back into the usage data set.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.

Abstract: The present disclosure provides a fuel injector for an internal combustion engine with a fuel injector body having a valve chamber, a first conduit in fluid communication with the valve chamber for a first flow of fuel having a first pressure, and a second conduit in fluid communication with the valve chamber for a second flow of fuel having a second pressure. The fuel injector further includes a valve member configured to move between the first conduit and the second conduit. Additionally, an actuator of the fuel injector is configured to move the valve member during a fuel injection cycle. The fuel injector is configured to operate in at least three modes.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.