Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralize TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: A high pressure fuel pump with parallel cooling fuel flow is disclosed wherein a fuel pump barrel having a substantially cylindrical plunger bore with an annular drain groove is provided. A first fuel path is provided that fluidically couples a fuel supply to an annular cooling ring formed on the outer surface of the barrel. The first fuel path further fluidically couples the annular cooling ring to a storage tank via an exit passage. A second, parallel fuel path is provided that fluidically couples the first fuel path to the drain groove, and further includes a drain passage fluidically coupled to the drain groove and the first fuel path via the storage tank.

Abstract: A fishing net system featuring a telescopic handle, one or more rim components, and one or more net components. The handle is removably attached to the rim component via an attachment base. The rim component is constructed from a first semicircular arc and a second semicircular arc, wherein the arcs can connect together form a generally circular ring. Protrusions are disposed on the ends of the arcs, which are adapted to engage slots in the attachment base. The curvature of the first arc faced outwardly, and the second arc is adapted to rotate in its slot in the attachment base. An end attachment means temporarily secures the second end of the first arc to the second end of the second arc. The net component has a first half sleeve and a second half sleeve adapted to receive the first arc and the second arc, respectively.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: A fuel injector is provided that creates variable spray characteristics to effectively reduce emissions, such as NOx emissions and particulate matter. The injector includes a nozzle valve element of the outwardly opening type including a fuel delivery passage and spray holes. The nozzle valve element is operable to move to a low lift position to cause fuel flowing from the spray holes to impinge on the injector body and to deflect toward the combustion chamber, and to move to a high lift position to cause fuel flowing from the spray holes to avoid impingement on injector body and flow in an obstructed manner directly into the combustion chamber. An annular chamber may be formed in the nozzle valve element adjacent the spray holes to receive fuel.

Abstract: The operation of a fuel injector for an internal combustion engine is controlled, wherein the fuel injector has an on time that includes a pull-in time during which injector current increases to a pull-in current followed by a hold time during which the injector current is limited to a hold current that is less than the pull-in current. A control circuit receives a pressure signal from a pressure sensor that corresponds to a pressure of fuel supplied to the fuel injector for injection into the engine, correlates the pressure signal with fuel pressure, and decreases the pull-in time with increasing fuel pressure.

Abstract: A high pressure pumping apparatus for of an internal combustion engine includes a pump barrel having a bore with a central axis, and a two-part pumping plunger provided in the bore of the barrel. The two-part plunger includes first and second pumping plunger parts that are separate from one another and arranged substantially coaxial with the central axis of the barrel's bore. A first distal end portion of the first pumping plunger part abuts a first distal end portion of the second pumping plunger part, and a second distal end portion of the first pumping plunger part in part defines a pumping chamber. The high pressure pumping apparatus includes and a tappet assembly that is operably coupled to the second distal end portion of the second pumping plunger part for operably engaging a rotating camshaft, which causes the first and second plunger parts to move in reciprocal motion.

Abstract: Methods and apparatus are provided for configuring a device based on proximity to another device. A user device is configured by obtaining one or more configuration rules that establish one or more configuration parameters of the user device based on a proximity to one or more additional general purpose devices; determining whether one or more of the configuration rules are satisfied; and configuring the user device based on the satisfied one or more configuration rules. The configuration rules can be configured by an authorized user of the user device. The proximity comprises a predefined physical relationship between devices that is based on distance, such as a radius around a given device, or a physical relationship, such as in the same room or building, or within a communication range of a device.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: Vehicular air bags formed from multilayer composites. The multilayer composites include a polymeric film and at least one tear resistant fabric attached to the polymeric film, and more particularly include a polymeric film, an open mesh, tear resistant fabric attached to the film and a fabric layer attached to the open mesh, tear resistant fabric. Air bags formed therefrom have low base weight, low elongation and high tear propagation resistance, protecting vehicle occupants from injury during and after air bag deployment.

Abstract: A high pressure fuel pump with parallel cooling fuel flow is disclosed wherein a fuel pump barrel having a substantially cylindrical plunger bore with an annular drain groove is provided. A first fuel path is provided that fluidically couples a fuel supply to an annular cooling ring formed on the outer surface of the barrel. The first fuel path further fluidically couples the annular cooling ring to a storage tank via an exit passage. A second, parallel fuel path is provided that fluidically couples the first fuel path to the drain groove, and further includes a drain passage fluidically coupled to the drain groove and the first fuel path via the storage tank.

Abstract: The present invention relates to compounds of Formula I or a stereomer, a tautomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereof, pharmaceutical formulations containing the compounds, methods of treatments using the compounds, for example, protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders and methods of preparing medicaments comprising the compounds.

Abstract: The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGF?), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralize TGF?1, TGF?2 and TGF?3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: A fuel pump is disclosed wherein a substantially cylindrical plunger bore is provided with an annular drain groove fluidically coupled to a drain duct. A pump plunger is driven by a drive system located in a separate mechanical compartment that holds a reservoir of lubricating oil. An annular seal is provided adjacent the drain groove substantially at the end of the bore and retained in position by a seal support. Exemplary embodiments provide the drain groove and seal as being positioned immediately adjacent one another so that the seal forms a lower wall of the drain groove.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: A system and method for increasing overall efficiency of a waste water system and increasing working efficiency of individual pump stations by implementing an overflow management system. The individual pump station facilitates delaying a discharge of fluid and stores waste water when a down stream pump station has reached a threshold level, thereby delaying or eliminating an overflow situation.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.