Abstract: Disclosed are methods to detect agents that modulate a membrane androgen receptor (mAR). In one embodiment, the invention provides a method to detect and optionally identify mAR binding ligands. One assay according to the invention detects agents that selectively bind the mAR relative to binding to the classical intracellular androgen receptor (iAR or AR). The invention has a wide spectrum of useful applications including providing a method of screening libraries for chemical entities that preferentially bind the mAR.

Abstract: Methods and apparatus are provided for selecting a service provider on a per-call basis A service provider is selected for a given call by receiving the given call from a caller; obtaining user preferences of the caller for the given call; matching the obtained user preferences to one or more capabilities of a plurality of available service providers; selecting a service provider for the given call based on the matching; and providing signaling to connect the caller and selected service provider The user preferences comprise can be default user preferences obtained from a database, preferences indicated by the caller as a part of the given call or a combination thereof Logging and report features are also disclosed

Abstract: Methods and apparatus are provided for configuring a device based on proximity to another device. A user device is configured by obtaining one or more configuration rules that establish one or more configuration parameters of the user device based on a proximity to one or more additional general purpose devices; determining whether one or more of the configuration rules are satisfied; and configuring the user device based on the satisfied one or more configuration rules. The configuration rules can be configured by an authorized user of the user device. The proximity comprises a predefined physical relationship between devices that is based on distance, such as a radius around a given device, or a physical relationship, such as in the same room or building, or within a communication range of a device.

Abstract: The operation of a fuel injector for an internal combustion engine is controlled, wherein the fuel injector has an on time comprising a pull-in time during which injector current increases to a pull-in current followed by a hold time during which the injector current is limited to a hold current that is less than the pull-in current. A control circuit receives a pressure signal from a pressure sensor that corresponds to a pressure of fuel supplied to the fuel injector for injection into the engine, correlates the pressure signal with fuel pressure, and decreases the pull-in time with increasing fuel pressure.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: The present invention relates to pyrimidine or pyridine carbamate compounds having the general Formula I: and pharmaceutically acceptable salts or derivatives thereof. Also included are methods of treatment of various diseases and conditions, including inflammation, inhibition of T cell activation and proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, Crohn's disease, lupus, hypersensitivity, type 1 diabetes, psoriasis, dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune diseases, glomerulonephritis, allergic diseases, asthma, hayfever, eczema, cancer, colon carcinoma, thymoma, just to name a few, in a mammal, the methods comprising administering a therapeutically-effective amount a compound of Formula I, or a salt or derivative form thereof, as described above.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A fluid control device for use in a high pressure fluid system, the device including a device body with a cavity and a high pressure circuit, a plunger positioned for reciprocal movement in the cavity, and a leakage reduction cap mounted to the plunger for reducing fluid leakage flow. In one implementation, the leakage reduction cap includes a flexible portion positioned between the device body and the plunger, and defining an annular clearance gap between the leakage reduction cap and the device body. The flexible portion of the leakage reduction cap resiliently flexes radially outwardly in response to fluid pressure forces to reduce the annular clearance gap so as to minimize fluid leakage flow through the annular clearance gap.

Abstract: The present invention comprises a program product, system and method for deposit processing using check images. In one embodiment of the present invention, the program product comprises machine-readable program code for causing, when executed, a machine to perform the following steps: at least one check processor receiving deposit information for a plurality of different deposit transactions, with the deposit information including original check image data and endorsed and voided check image data for at least one check to be deposited; selecting a print processor that has access to at least one printer based on at least one criterion; sending the electronic check data and check image data to the selected print processor; identifying a clearing end point; generating cash letter data for a maker bank; the print processor or the check processor transmitting the check image data and the cash letter data directly or indirectly to the selected end point and/or to at least one printer.

Abstract: Dental obturators are used in the preparation of root canals in teeth. The subject obturators are so constructed that they bind at a particular distance into the canal, thereby precluding possible damage at the end of the canal. A variety of structural configurations is disclosed.

Abstract: Vehicular air bags formed from multilayer composites. The multilayer composites include a polymeric film and at least one tear resistant fabric attached to the polymeric film, and more particularly include a polymeric film, an open mesh, tear resistant fabric attached to the film and a fabric layer attached to the open mesh, tear resistant fabric. Air bags formed therefrom have low base weight, low elongation and high tear propagation resistance, protecting vehicle occupants from injury during and after air bag deployment.

Abstract: The invention relates to methods of making carbohydrate and polyol esters suitable for use as plasticizers for polymer compositions. The invention also relates to plasticized polymer compositions comprising such carbohydrate and polyol esters. The invention also relates to articles prepared from such plasticized polymer compositions. The invention further relates to methods of using these compositions.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from capture sites that preprocess financial instruments and generate data from the original instruments, for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: A system that includes computer hardware, computer software, apparatus, and methodology that enables individuals, businesses, and all types of organizations (both for profit and non-profit) to capture and securely transmit check images (including, but not limited to, personal checks, business checks, travelers checks, money orders, merchant coupons, food coupons, line of credit checks, etc.), deposit information, and other information from remote locations (i.e., locations that could include the financial institution's remote locations, other financial institution's locations, businesses, private residences, etc.), for the purpose of having those checks credited to the depositing individual's or organization's bank account(s) and having the check images (and/or physical checks) entered into the bank check clearing channels for ultimate delivery to the maker bank for payment out of the maker's account.

Abstract: A tapered endodontic rotary file for shaping or cleaning a root canal in a tooth has one or more flutes spiraling along the length of the file. The diameters of the one or more flutes tapers in a non-uniform manner from a first diameter in a shank portion of the file to a smaller diameter in a tip portion of the file such that at least one flute region intermediate the shank portion and the tip portion has a diameter less than a straight line taper from the shank portion to the tip portion. The flutes can also be landed and the width of the lands can be varied along the length of the file. In particular, the width of the lands in the intermediate region are wider than the width in the tip or shank portion.

Abstract: A flow control valve for controlling the flow of fuel in a fuel system including a housing with a fuel passage, a valve device movable to close the fuel passage to block fuel flow through the fuel passage, and to open the fuel passage to permit fuel flow through the fuel passage, a valve plunger engaging the valve device, an actuator for reciprocally moving the valve plunger, an armature overtravel feature for permitting continued movement of the armature relative to the valve plunger from an engaged position into a disengaged position when the valve plunger reaches the extended position, and an armature stop for stopping overtravel of the armature.

Abstract: An piezoelectric actuated injector is provided which includes a nozzle valve element, a control volume, and an injection control valve including a control valve member for controlling fuel flow from the control volume so as to control nozzle valve movement. Importantly, the injector includes a preload chamber positioned along an injection control valve member for receiving high pressure fuel. The high pressure fuel acts on the injection control valve member to apply a preload force to supply a preload force to the stack of piezoelectric elements thereby ensuring more accurate control over fuel injection timing and metering.

Abstract: The invention encompasses compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions, uses and methods for prophylaxis and treatment of cancer.

Abstract: The invention relates to inhibitors of enzymes that bind to ATP or GTP and/or catalyze phosphoryl transfer, compositions comprising the inhibitors, and methods of using the inhibitors and inhibitor compositions. The inhibitors and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making phosphoryl transferase inhibitor compounds, methods of inhibiting phosphoryl transferase activity, and methods for treating disease or disease symptoms.