Abstract: Provided in the present application is a compound as represented by formula (1). The compound can regulate the KIF18A protein, thereby affecting the cell cycle and the cell proliferation process to treat cancer and cancer-associated diseases. The present disclosure further comprises a pharmaceutical composition containing the compound, and a method for treating conditions associated with the KIF18A activity.

Abstract: A molded component includes: an internal component including an electronic component body (detector element body) and a lead wire extending from the electronic component body (detector element body); a connection terminal connected to the lead wire a first molded part covering the internal component and holding the connection terminal, and a second molded part covering the first molded part. The second molded part has a non-water-exposed region located in a region where water exposure is suppressed, and a through-hole (outer through-hole) extending from a surface of the second molded part to reach the first molded part is formed only in the non-water-exposed region of the second molded part.

Abstract: A molded component 1 includes an internal component module including a first molded part, solder parts, and a second molded part. Lead wires include a first lead wire and a second lead wire. The first molded part includes a partition having a first face and a second face. The first lead wire has a first exposed section on the first face, and the second lead wire has a second exposed section on the second face. The first lead wire and the second lead wire are located at positions not overlapping with each other in a plan view from a direction in which the first face is oriented or a direction in which the second face is oriented. The solder parts include a first solder part located on the first face and a second solder part located on the second face.

Abstract: A treatment agent for an electronic-grade low-dielectric fiberglass cloth, and a preparation method thereof are provided. The treatment agent for an electronic-grade low-dielectric fiberglass cloth is prepared from the following raw materials in weight percentages: a coupling agent A: 0.6% to 1.2%, a coupling agent B: 0.3% to 0.8%, a coupling agent additive: 0.01% to 1.5%, an alcohol: 0.1% to 0.5%, an acid: 0.1% to 0.5%, and water: the balance, where the coupling agent A is a vinyl-containing coupling agent; the coupling agent B is a vinylbenzyl-containing coupling agent; and the coupling agent additive is a salt of a maleic anhydride (MA)-grafted copolymer. On the basis of meeting the low dielectric performance, the treatment agent of the present disclosure improves the binding performance of the low-dielectric fiberglass cloth to a low-dielectric customer resin and enhances the mechanical performance and heat resistance of the low-dielectric fiberglass cloth.

Abstract: Disclosed herein is a biochar controlled release fertilizer composition. Various embodiments include biochar and one or more nutrients encapsulated in a biodegradable polymer composite. Further embodiments of the controlled release fertilizer composition include one or more of alginate, kaolin, and waste water sludge. The nutrients of the fertilizer may be released such as to be available at the time needed for crop growth while minimizing waste and potentially harmful environmental effects.

Abstract: A treatment agent for an electronic-grade low-dielectric fiberglass cloth, and a preparation method thereof are provided. The treatment agent for an electronic-grade low-dielectric fiberglass cloth is prepared from the following raw materials in weight percentages: a coupling agent A: 0.6% to 1.2%, a coupling agent B: 0.3% to 0.8%, a coupling agent additive: 0.01% to 1.5%, an alcohol: 0.1% to 0.5%, an acid: 0.1% to 0.5%, and water: the balance, where the coupling agent A is a vinyl-containing coupling agent; the coupling agent B is a vinylbenzyl-containing coupling agent; and the coupling agent additive is a salt of a maleic anhydride (MA)-grafted copolymer. On the basis of meeting the low dielectric performance, the treatment agent of the present disclosure improves the binding performance of the low-dielectric fiberglass cloth to a low-dielectric customer resin and enhances the mechanical performance and heat resistance of the low-dielectric fiberglass cloth.

Abstract: The present invention relates to an immunomodulating peptide comprising an amino acid sequence as shown in SEQ ID NO:1. The present invention also discloses use of the immunomodulating peptide in the preparation of a drug or skin care product for promoting skin wound healing. The present invention provides a new immunomodulating peptide and use thereof, and discloses the mechanism of action of the immunomodulating peptide in promoting wound healing. The immunomodulating peptide is useful as a wounding healing polypeptide template.

Abstract: A release device, system, and method, and a therapeutic device are provided. The release device (100) comprises a power supply assembly (110), a current detector (120), a first timer (130) and a control unit (140). The power consumption of the release circuit and the accumulated time duration over which the current of the release circuit are less than a predetermined current value are used as a determination index of whether the release process is successful or not. Thus, misjudgment caused by current fluctuation can be avoided, and determination accuracy is improved. At the same time, the release system uses a self-loop structure, and therefore no electric discharge needle or electrode need be inserted into the body of a patient during actual use of the device, reducing the suffering of the patient.

Abstract: A release apparatus (100), a release system, a release method, and a treatment apparatus are disclosed. The release apparatus (100) uses two indicators, electric current and power comsuption, to determine whether the release process performed by the release system is successful. This reduces misjudgments, improves the accuracy of the determination of the release state. The release system also uses a self-loop structure, such that it is unnecessary to insert a conductive needle or electrode into the body of a patient, reducing the suffering of the patient.

Abstract: The present invention relates to an antibacterial peptide derived from Erythroculter ilishaeformis and use thereof. The amino acid sequence of the antibacterial peptide of the present invention includes an amino acid sequence as shown in SEQ ID NO: 1. The present invention further discloses use of the antibacterial peptide in the preparation of an anti-aquatic-bacterium drug for aquaculture animals. The present invention provides a novel antibacterial peptide, discloses a function of the novel antibacterial peptide for resisting aquatic bacteria, and provides candidate molecules for preventing and treating bacterial diseases in the culture process of Erythroculter ilishaeformis.

Abstract: The present invention relates to an immunomodulating peptide comprising an amino acid sequence as shown in SEQ ID NO:1. The present invention also discloses use of the immunomodulating peptide in the preparation of a drug or skin care product for promoting skin wound healing. The present invention provides a new immunomodulating peptide and use thereof, and discloses the mechanism of action of the immunomodulating peptide in promoting wound healing. The immunomodulating peptide is useful as a wounding healing polypeptide template.

Abstract: Methods of forming an EDNMOS with polysilicon fingers between a gate and a nitride spacer and the resulting devices are provided. Embodiments include forming a polysilicon layer upon a GOX layer over a substrate; forming a gate and plurality of fingers and a gate and plurality of fingers through the polysilicon layer down the GOX layer; forming an oxide layer over the GOX layer and sidewalls of the gates and fingers; forming a nitride layer over the oxide layer; removing portions of the nitride and oxide layers down to the polysilicon and GOX layers to form nitride spacers; and forming S/D regions laterally separated in the substrate, each S/D region adjacent to a nitride spacer.

Abstract: Methods of forming an EDNMOS with polysilicon fingers between a gate and a nitride spacer and the resulting devices are provided. Embodiments include forming a polysilicon layer upon a GOX layer over a substrate; forming a gate and plurality of fingers and a gate and plurality of fingers through the polysilicon layer down the GOX layer; forming an oxide layer over the GOX layer and sidewalls of the gates and fingers; forming a nitride layer over the oxide layer; removing portions of the nitride and oxide layers down to the polysilicon and GOX layers to form nitride spacers; and forming S/D regions laterally separated in the substrate, each S/D region adjacent to a nitride spacer.

Abstract: Methods of forming an EDNMOS with polysilicon fingers between a gate and a nitride spacer and the resulting devices are provided. Embodiments include forming a polysilicon layer upon a GOX layer over a substrate; forming a gate and plurality of fingers and a gate and plurality of fingers through the polysilicon layer down the GOX layer; forming an oxide layer over the GOX layer and sidewalls of the gates and fingers; forming a nitride layer over the oxide layer; removing portions of the nitride and oxide layers down to the polysilicon and GOX layers to form nitride spacers; and forming S/D regions laterally separated in the substrate, each S/D region adjacent to a nitride spacer.

Abstract: Methods of forming an EDNMOS with polysilicon fingers between a gate and a nitride spacer and the resulting devices are provided. Embodiments include forming a polysilicon layer upon a GOX layer over a substrate; forming a gate and plurality of fingers and a gate and plurality of fingers through the polysilicon layer down the GOX layer; forming an oxide layer over the GOX layer and sidewalls of the gates and fingers; forming a nitride layer over the oxide layer; removing portions of the nitride and oxide layers down to the polysilicon and GOX layers to form nitride spacers; and forming S/D regions laterally separated in the substrate, each S/D region adjacent to a nitride spacer.

Abstract: An apparatus comprising a data framer configured to frame a Media Access Control (MAC) control message for transmission, the MAC control message comprising an organization specific identifier (OUI) and at least one type-length-value (TLV) comprising a type field, a length field, and a value field, wherein a format of the TLV is specified by the OUI, and wherein the value field comprises information related to operation, administration, and maintenance (OAM) features of a network. Also included is an apparatus comprising at least one component configured to implement a method comprising compiling an OAM message comprising a plurality of organization-specific TLVs and an organization unique identifier (OUI) that indicates an organization responsible for the format of the TLV, and transmitting the OAM message.

Abstract: A passive optical network (PON) component comprising a power switch, a detector configured to monitor the power switch, and a processor configured to receive an interrupt from the detector and transmit a message comprising a first indicator that the PON component has powered down, and a second indicator giving a reason for the power down. A passive optical network (PON) component comprising a processor configured to implement a method comprising receiving an interrupt message from a detector, determining a reason for the interrupt, and transmitting a dying gasp message comprising an indicator of the reason for the interrupt. A method comprising transmitting an alarm message comprising an optical network terminal (ONT) manual power off indicator that indicates the ONT is shutting down because a subscriber has turned off its power switch.

Abstract: A passive optical network (PON) component comprising a power switch, a detector configured to monitor the power switch, and a processor configured to receive an interrupt from the detector and transmit a message comprising a first indicator that the PON component has powered down, and a second indicator giving a reason for the power down. A passive optical network (PON) component comprising a processor configured to implement a method comprising receiving an interrupt message from a detector, determining a reason for the interrupt, and transmitting a dying gasp message comprising an indicator of the reason for the interrupt. A method comprising transmitting an alarm message comprising an optical network terminal (ONT) manual power off indicator that indicates the ONT is shutting down because a subscriber has turned off its power switch.

Abstract: Reactors for the pyrolysis of pyrolyzable matter, pyrolysis systems incorporating the reactors and methods of using the reactors are provided. Also provided are systems and methods for integrating the pyrolysis and hydrodeoxygenation of pyrolyzable matter. The pyrolysis reactors create a horizontally rotating, fluidized-bed to which pyrolyzable matter, such as biomass, may be converted via pyrolysis into liquid fuels and/or value-added chemicals.