Abstract: Embodiments of a system and method for endoscope cleaning and inspection are disclosed. In an example, an endoscope cleaning and inspection unit includes cleaning and testing capabilities operated via control equipment and a display screen, to operate leak testing equipment, flush control equipment, and optical inspection equipment for leak testing, flushing, rinsing, and inspection of an endoscope interior chamber (lumen) and exterior surfaces. In a further example, the endoscope cleaning and inspection unit may further operate and receive information from a borescope imaging device or a magnification imaging device, using an imaging sensor to capture images of an endoscope lumen or surface respectively, as captured or output on the display screen. Further embodiments provide for control, monitoring, data collection, data input, and data output with such imaging devices via the endoscope cleaning and inspection unit.

Abstract: Embodiments of a system and method for endoscope cleaning and inspection are disclosed. In an example, an endoscope cleaning and inspection unit includes cleaning and testing capabilities operated via control equipment and a display screen, to operate leak testing equipment, flush control equipment, and optical inspection equipment for leak testing, flushing, rinsing, and inspection of an endoscope interior chamber (lumen) and exterior surfaces. In a further example, the endoscope cleaning and inspection unit may further operate and receive information from a borescope imaging device or a magnification imaging device, using an imaging sensor to capture images of an endoscope lumen or surface respectively, as captured or output on the display screen. Further embodiments provide for control, monitoring, data collection, data input, and data output with such imaging devices via the endoscope cleaning and inspection unit.

Abstract: A method and compression unit for compressing a block of image data to satisfy a target level of compression, wherein the block of image data comprises a plurality of image element values, each image element value comprising one or more data values relating to a respective channel. For each of the channels: (i) an origin value for the channel for the block is determined, (ii) difference values are determined representing differences between the data values and the determined origin value for the channel for the block, and (iii) a first number of bits for losslessly representing a maximum difference value of the difference values for the channel for the block is determined.

Abstract: The invention relates to a compound of formula (I) or formula (II) or pharmaceutically acceptable salts, solvates, tautomers, stereoisomers or mixtures thereof; which are useful as medicaments, in particular as anti-proliferative agents and for use as a drug in an antibody-drug conjugate and in the treatment of proliferative diseases.

Abstract: A liner for an endoscope storage tray is provided. The liner has an interior comprising a flexibly deformable material substantially impermeable to fluids and an absorbent material disposed within or attached to at least a portion of the flexibly deformable material. The liner is configured to temporarily line at least an interior of the endoscope storage tray. Systems and methods are also provided.

Abstract: An endoscope tray is provided. The tray comprises an interior for storage of an endoscope. The interior has an upstanding element having a top surface, and a plurality of apertures disposed on at least a portion of the top surface of the upstanding element to facilitate drainage of fluids. Systems and methods are also provided.

Abstract: A cart for storage of an endoscope is provided. The cart comprises a housing having a slot configured to slidably receive a tray. The tray is configured to store an endoscope, and a timer is coupled to the housing, slot and/or tray. The timer is configured to display increments of time that the endoscope is stored in the tray. Systems and methods are also provided.

Abstract: A method and compression unit for compressing a block of image data to satisfy a target level of compression, wherein the block of image data comprises a plurality of image element values, each image element value comprising one or more data values relating to a respective channel. For each of the channels: (i) an origin value for the channel for the block is determined, (ii) difference values are determined representing differences between the data values and the determined origin value for the channel for the block, and (iii) a first number of bits for losslessly representing a maximum difference value of the difference values for the channel for the block is determined.

Abstract: A decompression method determines image element values from compressed data representing a block of image element values relating to a respective one or more channels. For each of the channels, an indication of a first number of bits representing difference values between the data values and an origin value for the channel is read from the compressed data. For each of the channels, a second number of bits is obtained, wherein representations of the difference values for each of the channels are included in the compressed data using the second number of bits for that channel. The obtained second numbers of bits for the respective channels are used to read the representations of the difference values for the image element values being decompressed. Based on the representations of the difference values, a difference value is determined in accordance with the first number of bits for the channel.

Abstract: Various methods, apparatuses/systems, and media for implementing a data discovery module are disclosed. A repository includes one or more memories that stores application code for each application among a plurality of applications. A processor is operatively connected to the repository via a communication network.

Abstract: A cover for an endoscope storage tray is provided. The cover comprises a flexibly deformable material substantially impermeable to fluids. The flexibly deformable material is configured to be temporarily secured to the tray so as to cover an endoscope storage compartment of the tray. A one-way valve is attached to the cover that is configured to release air flowing from the endoscope storage compartment of the tray to the cover. Systems and methods are also provided.

Abstract: Systems, methods, and computer-readable media are provided to assist users to locate content of interest based on viewer ratings. First information enabling unique identification of a first user may be processed. Indications of ratings of television programming may be processed, the indications being received from a first media device associated with the first user. Ratings information associated with the first user may be retained in repositories, the ratings information being based on the indications. The first user may be matched to a category that represents a classification of a set of viewers and/or of a set of content based on a set of attributes. Descriptive content indicative of the first user and/or content rated by the first user may be selected and may be transmitted via the network to a second media device associated with a second user.

Abstract: A method and decompression unit for performing decompression to determine image element values from compressed data representing a block of image element values each comprising one or more data values relating to a respective one or more channels. An indication of an origin value for each of the channels is read from the compressed data. For each of the channels, an indication of a first number of bits for representing difference values between the data values and the origin value for the channel is read from the compressed data. For each of the one or more channels, a second number of bits is obtained, wherein representations of the difference values for each of the channels are included in the compressed data using the second number of bits for that channel. The obtained second numbers of bits for the respective channels are used to read the representations of the difference values for the image element values being decompressed from the compressed data.

Abstract: An apparatus for use in a method of decontaminating a device including a tray. A membrane permeable by a decontaminating fluid is positioned over the top of the tray to form an enclosed space. A lid is secured to the tray and the membrane is positioned between the tray and the lid. A hub assembly is positioned within the tray.

Abstract: An endoscope cleansing accessory is described for use at the bedside, manual cleaning sink, or prior to decontamination of the endoscope with an automatic endoscope reprocessing (AER) apparatus. The cleansing accessory includes a cleansing pod or bulbous package filled with a cleaning composition, such as a foam, fluid or powder, and a blocking mechanism located at or near an opening of the cleansing pod. The blocking mechanism is configured to block a suction channel once the cleansing pod is tightly fitted over a distal end of the endoscope. External pressure applied to the outside of the cleansing pod in the form of repeated compression or squeezing drives the cleaning fluid through an elevator platform or forceps raiser bridge mechanism within the endoscope's distal end to loosen tissue and other particles, which can then be flushed out during manual cleaning or by the flowing cleansing fluid of an AER.

Abstract: Embodiments of a system and method for endoscope cleaning and inspection are disclosed. In an example, an endoscope cleaning and inspection unit includes cleaning and testing capabilities operated via control equipment and a display screen, to operate leak testing equipment, flush control equipment, and optical inspection equipment for leak testing, flushing, rinsing, and inspection of an endoscope interior chamber (lumen) and exterior surfaces. In a further example, the endoscope cleaning and inspection unit may further operate and receive information from a borescope imaging device or a magnification imaging device, using an imaging sensor to capture images of an endoscope lumen or surface respectively, as captured or output on the display screen. Further embodiments provide for control, monitoring, data collection, data input, and data output with such imaging devices via the endoscope cleaning and inspection unit.

Abstract: Embodiments of a system and method of use for endoscope fluorescence inspection are generally described herein. In an example embodiment, a fluorescence inspection device provides capabilities for internal inspection of an endoscope lumen through a handheld unit coupled to a light pipe that identifies fluorescence from residual biological material exposed to a fluorescing agent. In another example embodiment, a fluorescence inspection device provides capabilities for external inspection of an endoscope surface through a handheld unit which emits excitation light and identifies fluorescence of residual biological material exposed to the fluorescing agent. The embodiments may also include an output device to output an indication in response to a detection (or lack of detection) of the fluorescent light with the fluorescence inspection device. Additional use examples and device structures are also described.

Abstract: The invention relates to a compound of formula (I): or pharmaceutically acceptable salts, solvates, tautomers, stereoisomers or mixtures thereof; wherein the fused ring moiety is a non-alkylating moiety; and wherein the compounds are useful as medicaments, in particular for use as a drug in an antibody-drug conjugate and in the treatment of a proliferative disease, a bacterial infection, a malarial infection and inflammation.

Abstract: The present application relate to crystalline azide compound of formula (II) which is used as an intermediate for the preparation of halichondrin B analogues such as eribulin or pharmaceutically acceptable salts thereof. The present application also covers purification process of azide compound of formula (II) and its further conversion to eribulin or a pharmaceutically acceptable salts thereof.