Patents by Inventor Mark Andrew

Mark Andrew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6178075
    Abstract: An electronic module comprising a power supply conductor coupled to one or more electromechanical actuators to supply operable power to the electromechanical actuators. The electronic module also includes a moisture sensor positioned to sense moisture intrusion into the module. Further, the electronic module comprises a first transistor responsively coupled to the moisture sensor, the first transistor coupled to draw current from the power supply conductor when the first transistor is in a conductive state. In addition, the electronic module includes a second transistor responsively coupled to the first transistor and in turn controllingly coupled to the first transistor.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: January 23, 2001
    Assignee: Visteon Global Technologies, Inc.
    Inventors: Mark Andrew Glinka Endicott, Vincent Colarossi, Viren Babubhai Merchant
  • Patent number: 6169053
    Abstract: This invention concerns a silylated porous microcomposite comprising a perfluorinated ion-exchange polymer entrapped within and highly dispersed throughout a network of inorganic oxide wherein the network and optionally the polymer have been modified with a silylating agent. These silylated microcomposites can be used in heterogeneous catalyst compositions for various chemical processes, such as in esterifications and acylations.
    Type: Grant
    Filed: September 21, 1999
    Date of Patent: January 2, 2001
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Andrew Harmer, Qun Sun
  • Patent number: 6162823
    Abstract: The present invention provides compounds having the of the formula I: ##STR1## and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: December 19, 2000
    Assignee: G.D. Searle & Co.
    Inventors: Thomas Dale Penning, Stella Siu-tzyy Yu, James Malecha, Chi-Dean Liang, Mark Andrew Russell
  • Patent number: 6159395
    Abstract: The present invention provides a process for the production of a synthesis gas mixture containing carbon oxides and hydrogen from a hydrocarbon feedstock material comprising: providing a reforming zone having a plurality of chambers charged with a catalyst effective for catalysis of at least one reforming reaction; supplying to the chambers of the reforming zone a vaporous mixture of the hydrocarbon feedstock and a reforming reagent; maintaining the reforming zone under suitable reforming conditions for reforming of the hydrocarbon feedstock and reforming reagent to form the synthesis gas mixture by supplying to the reforming zone a fuel for heating the chambers by combustion and by supplying to the steam reforming zone a vaporous steam comprising combustion oxygen in which the fuel may be combusted; humidifying the vaporous steam comprising combustion oxygen; exchanging heat between the humidified vaporous steam comprising combustion oxygen entering the reforming zone and the synthesis gas mixture exiting th
    Type: Grant
    Filed: August 7, 1998
    Date of Patent: December 12, 2000
    Assignee: Kvaerner Process Technology Limited
    Inventors: Simon Robert Early, Timothy Douglas Gamlin, Mark Andrew Linthwaite
  • Patent number: 6160190
    Abstract: Porous microcomposites have been prepared from perfluorinated ion-exchange polymer and metal oxides such as silica using the sol-gel process. Such microcomposites possess high surface area and exhibit extremely high catalytic activity. The microcomposites catalyze, among others, the reaction between organic aromatic compounds and olefins.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: December 12, 2000
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Andrew Harmer, Qun Sun
  • Patent number: 6144489
    Abstract: A confocal microscope comprises a light source, a focusing arrangement, a detector and an encoded mask (17). The light source illuminates the mast (17) and the encoded light is then focused on a specimen. Light from the specimen is then decoded, by either the same or a separate complementary mask, before being detected, for example by a camera. The mask (17) is encoded with a pattern which generates a combined confocal and non-confocal image and the confocal image is subsequently extracted from the combined image. This means that confocal images of different regions of the specimen can be produced simultaneously, which in turn enables real-time confocal imaging of the specimen. In addition, as the microscope is no longer restricted to delta correlated images, an improvement in the light budget can also be achieved.
    Type: Grant
    Filed: August 21, 1998
    Date of Patent: November 7, 2000
    Assignee: Isis Innovation Limited
    Inventors: Tony Wilson, Mark Andrew Aquilla Neil, Rimvydas Juskaitis
  • Patent number: 6134825
    Abstract: A container for fishing lures, the fishing lures having pointed fishhooks, the container consisting of a styrofoam fishhook point receiving block having an axis of rotation; a cylinder having an outer surface, an interior space, a wall, the wall having a fishing lure insertion and retrieval aperture therethrough, and a pair of ends; a pair of end covering plates fixedly attached to the cylinder, the end covering plates covering the ends of the cylinder; a drive axle rotatably mounting the styrofoam fishhook point receiving block within the interior space of the cylinder, the drive axle positioning such block therein so that its axis of rotation extends through the pair of end covering plates; a slide plate; and a pair of slide channels fixedly attached to the cylinder, the slide channels slidably mounting the slide plate upon the cylinder so that the slide plate may alternately slidably move between a first position wherein the slide plate covers the fishing lure insertion and retrieval aperture, and a second
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: October 24, 2000
    Inventors: Loren Paul Moffett, deceased, by Dora Mae Moffett, legal representative, by Paul Michael Moffett, legal representative, by David Wayne Moffett, legal representative, by Mark Andrew Moffett, legal representative
  • Patent number: 6131614
    Abstract: A convoluted flexible protective sleeve comprises a wall made of heat-resistant plastics material and a layer of infra-red radiation-reflecting metal vacuum deposited on the outer surface of said wall. The layer is between 0.05 and 5 micrometers in thickness.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: October 17, 2000
    Assignee: T&N Technology Limited
    Inventors: David Raymond Eastham, Mark Andrew Poole, Anthony Salvatore Laskey
  • Patent number: 6133493
    Abstract: This invention concerns a modified porous microcomposite comprising a perfluorinated ion-exchange polymer entrapped within and highly dispersed throughout a network of inorganic oxide wherein the network and optionally the pendant groups of the polymer have been modified with a Lewis acid. These modified microcomposites can be used in catalyst compositions for various chemical processes, such as in the alkylation or acylation of aromatics.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: October 17, 2000
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Andrew Harmer, Qun Sun
  • Patent number: 6128582
    Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of IMPDH. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to IMPDH or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of IMPDH or close structural homologues of the active site binding pockets. This invention also relates to compounds and pharmaceutical compositions which are inhibitors of IMPDH.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: October 3, 2000
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Keith P. Wilson, Michael D. Sintchak, Mark Andrew Fleming, David M. Armistead
  • Patent number: 6127372
    Abstract: This invention provides a novel class of sulfonamide compounds of formula I which are aspartyl protease inhibitors: ##STR1## This invention also provides pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also provides methods for inhibition aspartyl protease activity and methods for treating viral infections using the compounds and compositions of this invention.
    Type: Grant
    Filed: April 1, 1996
    Date of Patent: October 3, 2000
    Assignee: Vertex Pharmaceuticals, Incorporated
    Inventors: Roger Dennis Tung, Francesco Gerald Salituro, David D. Deininger, Mark Andrew Murcko, Perry Michael Novak, Govinda Rao Bhisetti
  • Patent number: 6117417
    Abstract: Mouthwash compositions are described comprising cetylpyridinium chloride and amidobetaine amphoteric surfactants of formula (I): RC(O)NH(CH.sub.2).sub.a N.sup.+ (R.sup.1)(R.sup.2)(CH.sub.2).sub.b CO.sub.2.sup.-, wherein R is C.sub.10-20 alkyl; R.sup.1 and R.sup.2 are independently C.sub.1-4 alkyl; a is an integer from 1 to 4; and b is an integer from 1 to 4.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: September 12, 2000
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Mark Andrew Wicks, Peter Scott McConville, Paula Walsh
  • Patent number: 6113394
    Abstract: A system (11) for presenting textual and/or graphical information for reading. The system includes a visual display unit (15) for displaying the textual and/or graphical information within a general layout screen, a microcomputer including processing means (13) to receive the textual and/or graphical information in an electronically encoded form and process the same for presentation on the visual display unit (15). A computer program (19) is provided for controlling the presentation of the textual and/or graphical information on the visual display unit (15) in a prescribed manner. A keyboard and mouse input (17) is included for inputting control signals to operate the processing means (13) and the computer program (19) or for altering control parameters of same.
    Type: Grant
    Filed: May 2, 1997
    Date of Patent: September 5, 2000
    Assignee: Charon Holdings Pty Ltd
    Inventor: Mark Andrew Edgar
  • Patent number: 6114493
    Abstract: This invention relates to methods for preparing novel, solid-phase transfer reagents, specifically phosgenated oxime resins and non-symmetrical ureas, that are useful as supports in combinatorial synthesis for the creation of libraries of compounds for lead identification.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: September 5, 2000
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Mark Andrew Scialdone
  • Patent number: 6110944
    Abstract: The present invention provides compounds having the structureAr.sub.1 --Q--Ar.sub.2 --O--(CH.sub.2).sub.n --Zand pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: August 29, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Barbara Baosheng Chen, Helen Chen, Mark Andrew Russell
  • Patent number: 6107233
    Abstract: A process for the preparation of at least one spherically shaped porous microcomposite is provided which microcomposite comprises a perfluorinated ion-exchange polymer containing pendant sulfonic and/or carboxylic acid groups entrapped within and highly dispersed throughout a network of inorganic oxide, wherein the weight percentage of the perfluorinated ion-exchange polymer in the microcomposite is from about 0.1 to about 90 percent, and wherein the size of the pores in the microcomposite is about 0.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: August 22, 2000
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Andrew Harmer, Qun Sun
  • Patent number: 6095897
    Abstract: A grinding machine for grinding the edge of a disc or wafer comprises a grooved grinding wheel 308, means for transporting the wafers before or after grinding, and a housing 332 in which wafers 340 are parked on a vacuum chuck 336 awaiting inspection. A jet 338 protrudes into the housing and directs water or air towards the face and edge of the wafer on the chuck. The transport means then transfers wafers to an inspection station.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: August 1, 2000
    Assignee: Unova U.K. Limited
    Inventors: Mark Andrew Stocker, Dermot Robert Falkner, Paul Martin Howard Morantz, Michael George Pierse
  • Patent number: 6096724
    Abstract: The present invention provides certain 6-hetarylalkyloxy pyrimidine derivatives of formula II ##STR1## wherein R is (i) a cyclic group having at least one 5- or 6-membered heterocyclic ring, optionally with a carbocyclic or heterocyclic ring fused thereto, the or each heterocyclic ring having at least one hetero atom chosen from O, N, or S, or a substituted derivative thereof; or (ii) phenyl or a substituted derivative thereof,R.sup.2 is selected from H, C.sub.1 -C.sub.5 alkyl, halogen or NH.sub.2,R.sup.4 and R.sup.5 which are the same or different are selected from H, NH.sub.2 or NO.sub.n where n=1 or 2, or R.sup.4 and R.sup.5 together with the pyrimidine ring form a 5- or 6-membered ring structure containing one or more heterocyclic atoms, and pharmaceutically acceptable salts thereof, exhibit the ability to deplete O.sup.6 -alkylguanine-DNA alkyltransferase (ATase) activity.
    Type: Grant
    Filed: June 2, 1998
    Date of Patent: August 1, 2000
    Assignee: Cancer Research Campaign Technology Limited
    Inventors: Thomas Brian Hamilton McMurry, Robert Stanley McElhinney, Joan Elizabeth McCormick, Dorothy Josephine Donnelly, Paul Murray, Christophe Carola, Rhoderick Hugh Elder, Jane Kelly, Geoffrey Paul Margison, Amanda Jean Watson, Joseph Anthony Rafferty, Mark Andrew Willington, Mark Ross Middleton
  • Patent number: 6091374
    Abstract: An ultra-wideband magnetic antenna includes a planar conductor having a first and a second slot about an axis. The slots are substantially leaf-shaped having a varying width along the axis. The slots are interconnected along the axis. A cross polarized antenna system is comprised of an ultra-wideband magnetic antenna and an ultra-wideband dipole antenna. The magnetic antenna and the dipole antenna are positioned substantially close to each other and they create a cross polarized field pattern. The present invention provides isolation between a transmitter and a receiver in an ultra-wideband system. Additionally, the present invention allows isolation among radiating elements in an array antenna system.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: July 18, 2000
    Assignee: Time Domain Corporation
    Inventor: Mark Andrew Barnes
  • Patent number: D427170
    Type: Grant
    Filed: March 17, 1999
    Date of Patent: June 27, 2000
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Mark Andrew Edwards, Alexander Ross, Robin WC Chu, Midori Yonezawa, Tadamasa Hayakawa