Patents by Inventor Ming-Cheng Chang

Ming-Cheng Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250135046
    Abstract: Disclosed herein is a drug complex having a synthetic peptide, which has an amino acid sequence of SEQ ID: NO.1; a metal chelator coupled to the synthetic peptide; and a peptide chain disposed between the synthetic peptide and the metal chelator, wherein the peptide chain is composed of plural glutamate molecules.
    Type: Application
    Filed: October 27, 2023
    Publication date: May 1, 2025
    Inventors: MING-CHENG CHANG, CHUN-TANG CHEN, PING-FANG CHIANG, CHENG-LIANG PENG
  • Publication number: 20240342627
    Abstract: A waterproof heating module for a smoke generator comprises a heat exchanger (45) including an ejection portion (115) configured to eject smoke. The heat exchanger (45) is received in an inner side of an outer casing (135). The ejection portion (115) extends through a through-hole (139) of the outer casing (135) to an outer side of the outer casing (135). A closure plate (155) includes a closure face (157) and a coupling hole (159) extending through the closure face (157). The coupling hole (159) of the closure plate (155) has an inner periphery (160) in waterproof coupling with an outer periphery of the ejection portion (115). The ejection portion (115) extends out of the closure plate (155) via the coupling hole (159). The closure face (157) of the closure plate (155) is in waterproof coupling with the through-hole (139) of the outer casing (135).
    Type: Application
    Filed: September 25, 2023
    Publication date: October 17, 2024
    Inventor: Ming-Cheng Chang
  • Publication number: 20240228663
    Abstract: Disclosed herein an isolated neutralizing antibody, which is capable of specifically binding to chitinase-3-like protein-1 (YKL-40) and uses thereof. The neutralizing antibody can further conjugate with a metal chelator to form an antibody complex. Further, labeling the antibody complex with a radioactive metal nuclide results in formation of a radioactive antibody complex, which can be used as a contrast agent and treatment for YKL-40 over-expression-related diseases. The radioactive antibody complex can specifically bind to YKL-40, and can be used for diagnosis and the preparation of the use of the treatment for cancers related to YKL-40 over-expression.
    Type: Application
    Filed: April 19, 2023
    Publication date: July 11, 2024
    Inventors: Ming-Cheng Chang, Ping-Fang Chiang, Yu-Jen Kuo
  • Publication number: 20240219094
    Abstract: A snowflake machine (10) comprises a blower (84) and an outlet device (72) is connected to the blower (84). The outlet device (72) includes a primary passageway (80) and a secondary passageway (82) around the primary passageway (80). The blower (84) operates to generate air currents which drives bubbles to pass through the primary passageway (80), thereby pushing the bubbles into the air. Air currents passing through the secondary passageway (82) to push the bubbles farther away from the outlet device (72).
    Type: Application
    Filed: November 14, 2023
    Publication date: July 4, 2024
    Inventor: Ming-Cheng Chang
  • Publication number: 20240132621
    Abstract: Disclosed herein an isolated neutralizing antibody, which is capable of specifically binding to chitinase-3-like protein-1 (YKL-40) and uses thereof. The neutralizing antibody can further conjugate with a metal chelator to form an antibody complex. Further, labeling the antibody complex with a radioactive metal nuclide results in formation of a radioactive antibody complex, which can be used as a contrast agent and treatment for YKL-40 over-expression-related diseases. The radioactive antibody complex can specifically bind to YKL-40, and can be used for diagnosis and the preparation of the use of the treatment for cancers related to YKL-40 over-expression.
    Type: Application
    Filed: April 18, 2023
    Publication date: April 25, 2024
    Inventors: Ming-Cheng Chang, Ping-Fang Chiang, Yu-Jen Kuo
  • Patent number: 11952320
    Abstract: An aqueous solution (20) containing carbohydrate for generating smoke consists of 91.9-98.95 wt % of pure water, 1-8 wt % of carbohydrate, and 0.05-0.1 wt % of a water soluble aromatic substance of orange flavor. A method for generating smoke includes preparing an aqueous solution (20) including 91.9-98.95 wt % of pure water, 1-8 wt % of carbohydrate, and 0.05-0.1 wt % of a water soluble aromatic substance of orange flavor; and vibrating the aqueous solution (20) at a high frequency, causing gradual atomization from a surface of the aqueous solution (20) to form droplets containing the carbohydrate and having a diameter in a range of 6-20 ?m.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: April 9, 2024
    Assignee: NOVACORP INC.
    Inventor: Ming-Cheng Chang
  • Patent number: 11779856
    Abstract: A smoke generator includes a casing having a first chamber receiving dry ice, a second chamber receiving water, and a third chamber. The casing includes an outer side having a smoke outlet intercommunicating with the second chamber. The first chamber includes a smoke discharge port intercommunicating with the second chamber. A water pump device in the third compartment includes a water inlet located in the second chamber and a water spraying end located in the first chamber. The water pump device delivers water in the second chamber to the first chamber. The dry ice contacts with the water and gasifies into smoke that enters the second chamber via the smoke discharge port and is then ejected out via the smoke outlet. Water in the first chamber is flowable back to the second chamber. A heater is disposed in the second chamber and can increase the temperature of the water.
    Type: Grant
    Filed: August 25, 2020
    Date of Patent: October 10, 2023
    Assignee: NOVACORP INC.
    Inventor: Ming-Cheng Chang
  • Publication number: 20230264221
    Abstract: An atomization device includes an atomization machine and an atomization bottle which can be disposed after use. The atomization bottle receives a liquid to be atomized to form a mist. The atomization bottle includes an atomization bottle cork to prevent leakage of the liquid. The atomization bottle cork includes an atomizer fee of power and any control module. A power supply and a control module are disposed on a machine body of the atomization machine. When the atomization bottle is coupled with the atomization machine, the atomizer can be activated by the control module to generate a mist. After the liquid in the atomization bottle is used up, the atomization bottle can be replaced by a new atomization bottle.
    Type: Application
    Filed: December 21, 2022
    Publication date: August 24, 2023
    Inventor: Ming-Cheng Chang
  • Patent number: 11541324
    Abstract: A smoke generator includes an oil tank receiving an oil to be pumped by an oil pump to a vaporization tube where the oil vaporized into smoke after heating by a heater. A pre-pressurization oil supply device is disposed between the vaporization tube and the oil pump. When the pre-pressurization oil supply device is in a non-supply state not intercommunicating with the vaporization tube, the pre-pressurization oil supply device maintains its internal pressure, and the oil in the pre-pressurization oil supply device is not delivered to the vaporization tube. When the pre-pressurization oil supply device is in an oil supply state, the pre-pressurization oil supply device intercommunicates with the vaporization tube, and the oil in the pre-pressurization oil supply device is rapidly delivered to the vaporization tube.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: January 3, 2023
    Assignee: NOVACORP INC.
    Inventor: Ming-Cheng Chang
  • Publication number: 20220062783
    Abstract: A smoke generator includes a casing having a first chamber receiving dry ice, a second chamber receiving water, and a third chamber. The casing includes an outer side having a smoke outlet intercommunicating with the second chamber. The first chamber includes a smoke discharge port intercommunicating with the second chamber. A water pump device in the third compartment includes a water inlet located in the second chamber and a water spraying end located in the first chamber. The water pump device delivers water in the second chamber to the first chamber. The dry ice contacts with the water and gasifies into smoke that enters the second chamber via the smoke discharge port and is then ejected out via the smoke outlet. Water in the first chamber is flowable back to the second chamber. A heater is disposed in the second chamber and can increase the temperature of the water.
    Type: Application
    Filed: August 25, 2020
    Publication date: March 3, 2022
    Inventor: Ming-Cheng Chang
  • Patent number: 11191718
    Abstract: The present invention provides an ophthalmic gel and a preparation method thereof. The ophthalmic gel comprises: an antibiotic; a nanocarrier, wherein the nanocarrier is used to load the antibiotic; and a biodegradable matrix, wherein the biodegradable matrix is compatible with the nanocarrier to carry the nanocarrier. When the ophthalmic gel of the present invention is applied to the surface of the cornea and conjunctiva of the eyes, the biodegradable matrix is automatically degraded and the nanocarrier carried by the biodegradable matrix will slowly release the antibiotic, loaded in the nanocarrier, at an appropriate rate to overcome the high-frequency use of general ophthalmic drugs and easily caused blurred vision; the present invention further comprises an ophthalmic gel preparation method.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: December 7, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Ming-Cheng Chang, Tsai-Yueh Luo, Cheng-Liang Peng, Kuan-Yin Chen
  • Patent number: 11127860
    Abstract: Structures for an extended-drain field-effect transistor and methods of forming an extended-drain field-effect transistor. A source region is coupled to a semiconductor layer, a drain region is coupled to the semiconductor layer, and a first gate structure is positioned over a channel region of the semiconductor layer. An extended drain region is positioned between the channel region and the drain region. The extended drain region includes a portion of the semiconductor layer between the first gate structure and the drain region. A second gate structure is arranged over the portion of the semiconductor layer.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: September 21, 2021
    Assignee: GLOBALFOUNDRIES U.S. INC.
    Inventors: Ming-Cheng Chang, Nigel Chan
  • Publication number: 20210253493
    Abstract: An aqueous solution (20) containing carbohydrate for generating smoke includes 91.9-98.95 wt % of pure water, 1-8 wt % of carbohydrate, and 0.05-0.1 wt % of a water soluble aromatic substance of orange flavor. A method for generating smoke includes preparing an aqueous solution (20) containing carbohydrate comprising 91.9-98.95 wt % of pure water, 1-8 wt % of carbohydrate, and 0.05-0.1 wt % of a water soluble aromatic substance of orange flavor; and vibrating the aqueous solution (20) at a high frequency, causing gradual atomization from a surface of the aqueous solution (20) to form droplets containing the carbohydrate and having a diameter in a range of 6-20 ?m.
    Type: Application
    Filed: January 15, 2021
    Publication date: August 19, 2021
    Inventor: Ming-Cheng Chang
  • Patent number: 11077383
    Abstract: A nozzle includes an expansion portion and a coupling portion having an inner end, an outer end, and an air hole extending from the inner end through the outer end. A connecting portion is connected between the expansion portion and the inner end and includes an opening intercommunicating with the air hole. The nozzle is coupled with a neck of a balloon. The expansion portion spreads the neck. The opening is received in the neck. The air hole intercommunicates with an inflation space defined in the balloon when a gas with a sufficient pressure is filled into the air hole. The air hole does not intercommunicate with the inflation space when no gas with the sufficient pressure is filled into the air hole.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: August 3, 2021
    Assignee: NOVACORP INC.
    Inventor: Ming-Cheng Chang
  • Publication number: 20210083095
    Abstract: Structures for an extended-drain field-effect transistor and methods of forming an extended-drain field-effect transistor. A source region is coupled to a semiconductor layer, a drain region is coupled to the semiconductor layer, and a first gate structure is positioned over a channel region of the semiconductor layer. An extended drain region is positioned between the channel region and the drain region. The extended drain region includes a portion of the semiconductor layer between the first gate structure and the drain region. A second gate structure is arranged over the portion of the semiconductor layer.
    Type: Application
    Filed: September 12, 2019
    Publication date: March 18, 2021
    Inventors: Ming-Cheng Chang, Nigel Chan
  • Publication number: 20200345631
    Abstract: The present invention provides an ophthalmic gel and a preparation method thereof. The ophthalmic gel comprises: an antibiotic; a nanocarrier, wherein the nanocarrier is used to load the antibiotic; and a biodegradable matrix, wherein the biodegradable matrix is compatible with the nanocarrier to carry the nanocarrier. When the ophthalmic gel of the present invention is applied to the surface of the cornea and conjunctiva of the eyes, the biodegradable matrix is automatically degraded and the nanocarrier carried by the biodegradable matrix will slowly release the antibiotic, loaded in the nanocarrier, at an appropriate rate to overcome the high-frequency use of general ophthalmic drugs and easily caused blurred vision; the present invention further comprises an ophthalmic gel preparation method.
    Type: Application
    Filed: August 13, 2019
    Publication date: November 5, 2020
    Inventors: Ming-Cheng Chang, Tsai-Yueh Luo, Cheng-Liang Peng, Kuan-Yin Chen
  • Publication number: 20200324217
    Abstract: A nozzle includes an expansion portion and a coupling portion having an inner end, an outer end, and an air hole extending from the inner end through the outer end. A connecting portion is connected between the expansion portion and the inner end and includes an opening intercommunicating with the air hole. The nozzle is coupled with a neck of a balloon. The expansion portion spreads the neck. The opening is received in the neck. The air hole intercommunicates with an inflation space defined in the balloon when a gas with a sufficient pressure is filled into the air hole. The air hole does not intercommunicate with the inflation space when no gas with the sufficient pressure is filled into the air hole.
    Type: Application
    Filed: March 9, 2020
    Publication date: October 15, 2020
    Inventor: Ming-Cheng Chang
  • Publication number: 20200230515
    Abstract: A smoke generator includes an oil tank (20) receiving an oil to be pumped by an oil pump (42) to a vaporization tube (157) where the oil vaporized into smoke after heating by a heater (159). A pre-pressurization oil supply device (72) is disposed between the vaporization tube (157) and the oil pump (42). When the pre-pressurization oil supply device (72) is in a non-supply state not intercommunicating with the vaporization tube (157), the pre-pressurization oil supply device (72) maintains its internal pressure, and the oil in the pre-pressurization oil supply device (72) is not delivered to the vaporization tube (157). When the pre-pressurization oil supply device (72) is in an oil supply state, the pre-pressurization oil supply device (72) intercommunicates with the vaporization tube (157), and the oil in the pre-pressurization oil supply device (72) is rapidly delivered to the vaporization tube (157).
    Type: Application
    Filed: November 29, 2019
    Publication date: July 23, 2020
    Inventor: Ming-Cheng Chang
  • Patent number: 10593674
    Abstract: Structures for field-effect transistors and methods for fabricating a structure for field-effect transistors. A logic cell includes first and second field-effect transistors and a well defining a back gate that is arranged beneath the first and second field-effect transistors. A dielectric layer is arranged between the well and the logic cell. A plurality of deep trench isolation regions extend through the dielectric layer and are arranged to surround the first and second field-effect transistors and the well. The back gate is shared by the first and second field-effect transistors.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: March 17, 2020
    Assignee: GLOBALFOUNDRIES INC.
    Inventors: Ming-Cheng Chang, Nigel Chan, Elliot John Smith
  • Patent number: D932119
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: September 28, 2021
    Assignees: Excelsior Medical Co., Ltd., Hung Hsing Electric Co., Ltd.
    Inventor: Ming-Cheng Chang