Abstract: A sound control mat includes a waterproof separation layer, an entangled monofilament structure, and a meltblown nonwoven. The sounds control mat provides improved sound control such as improved impact insulation.

Abstract: This invention relates to novel agents that are analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and their conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.

Abstract: The present invention relates to a thermally insulating batt comprising: (i) 10 to 70% by weight staple flash spun plexifilamentary fibers or staple melt spun fibrillated fibers; (ii) 10 to 70% by weight staple fibers; and (ii) 5 to 30% by weight binding agent that can also be used in a thermally insulating composite suitable for use in exterior portions of residential and commercial buildings.

Abstract: Examples described herein provide for generating a multicast consumer search request from a request node in the network. The request is then routed to the interconnected nodes and received at a target node having a directly-connected multicast consumer. Identification information associated with the directly-connected multicast consumer is forwarded from the target node back to the request node.

Abstract: A tool and method for forming a container from a construct. The tool comprising a cavity for receiving a construct, a core operatively associated with the cavity and being operable to move into the cavity, an injection cavity for receiving injection-molding material and directing injection-molding material around at least a portion of the perimeter of the construct, and a clamping feature. The clamping feature is operatively connected to at least one of the cavity and the core and is for clamping a peripheral portion of the construct as the core moves into the cavity to form the construct into the container.

Abstract: A non-woven web, comprising one or more polymeric fibers, wherein the number-average fiber diameter distribution of said one or more polymeric fibers conforms to a Johnson unbounded distribution. Non-woven webs comprising such polymeric fibers are rendered with mean-flow pore size and porosity desirable for specific filtration applications such as hepafiltration.

Abstract: A container or tray having various features. The container or tray comprises at least one sidewall having a top edge, the top edge of the at least one sidewall corresponding to a top surface of the tray and a bottom surface adjacent to the sidewall. A flange extends laterally outward from the top edge and is foldably connected to the sidewall at the top edge. The flange comprises at least a portion of the top surface of the tray. An injection-molded feature at least partially encapsulates the flange. The injection-molded feature comprising resin and has a first region in contact with the sidewall and at least a portion of the flange, and a second region adjacent the first region and extending laterally outward from the first region to a free edge of the injection-molded feature. The first region has a greater cross-sectional area than the second region.

Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.

Abstract: A tool for creating a container or tray having various features. The tool comprises a cavity operable to receive a blank. The cavity has at least one sidewall for forming at least one sidewall of the container. A core is operatively connected to the cavity. The core is operable to enter the cavity to least partially form the blank into the container. An injection cavity is for receiving liquid resin and directing liquid resin around at least a portion of the perimeter of the blank. The injection cavity comprises an advanced-flow section and a delayed-flow section. The advanced-flow section has a greater cross-sectional area than the delayed-flow section, and the advanced-flow section is located adjacent the at least one sidewall of the cavity.

Abstract: This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.

Abstract: A non-woven web, comprising one or more polymeric fibers, wherein the number-average fiber diameter distribution of said one or more polymeric fibers conforms to a Johnson unbounded distribution. Non-woven webs comprising such polymeric fibers are rendered with mean-flow pore size and porosity desirable for specific filtration applications such as hepafiltration.

Abstract: The present invention relates to a liquid filtration medium comprising at least one nonwoven sheet wherein the nonwoven sheet has a water flow rate of at least 10 ml/min/cm2/KPa and a tortuosity filter factor of at least 3.0. The liquid filtration medium can be used in a filter system with an optional pre-filter layer or microfiltration membrane.

Abstract: A container or tray having various features. Also, the invention is generally directed to a method of forming the container or tray and a tool or apparatus for forming the container or tray.

Abstract: A fast hardening clear coating composition for repairing a clear coat/color coat finish or a pigmented mono-coat of a vehicle comprising a film forming binder and an organic liquid carrier, where the binder contains a hydroxyl polymer component comprising (A) hydroxyl-containing acrylic polymer, (B) at least one hydroxyl-terminated component selected from the group consisting of (1) an organic diol having the formula where R1 and R2 are individually selected from the group of hydrogen and an alkyl group having 1, 3-5 carbon atoms and (2) a hydroxyl terminated reaction product of trimethylol propane and a lactone; (C) an organic polyisocyanate crosslinking component, at least portion of which comprises a trimer of isophorone diisocyanate or hexamethylene diisocyanate and the composition further contains, a curing catalyst, of a dialkyl tin aliphatic carboxylate, a tertiary aliphatic mono or diamine, an aliphatic carboxylic acid, and optionally, a zinc or calcium organic acid salt in an effective amount suc

Abstract: The present disclosure relates to an isocyanate terminated saturated hydrocarbon polymer that can be used as a crosslinking agent in a coating composition. The coating composition can provide a composition that adheres well to resinous substrates. Also provided are coating composition comprising the crosslinking agent and methods for producing the adherent coating composition.

Abstract: A tool for creating a container or tray having various features. The tool comprises a cavity operable to receive a blank. The cavity has at least one sidewall for forming at least one sidewall of the container. A core is operatively connected to the cavity. The core is operable to enter the cavity to least partially form the blank into the container. An injection cavity is for receiving liquid resin and directing liquid resin around at least a portion of the perimeter of the blank. The injection cavity comprises an advanced-flow section and a delayed-flow section. The advanced-flow section has a greater cross-sectional area than the delayed-flow section, and the advanced-flow section is located adjacent the at least one sidewall of the cavity.

Abstract: The present invention relates to an adhesion promoting cleaner solution for producing and adherent coating on a resinous substrate. The adhesion promoting cleaning solution comprises a telechelic diol in a carrier liquid such as an organic solvent. Also disclosed is a process of using the adhesion promoting cleaner solution to produce an adherent coating on a resinous substrate.

Abstract: This invention relates to compounds comprising one or more therapeutic and/or diagnostic moieties and one or more functional moieties linked together via one or more triazole-containing linkers and to their intermediates and methods of their preparation. The triazole-containing linker may optionally contain one or more conditionally-cleavable or conditionally-transformable moieties and one or more spacer systems in between said moiety/moieties and the one or more therapeutic and/or diagnostic moieties.

Abstract: A spreading apparatus for spreading material onto a target area is disclosed. The spreading apparatus includes a container for the material, a discharge unit which discharges the material, a deflector door disposed on a discharge port of the discharge unit, a positioning device which positions the deflector door and a controller configured to control the deflector door so that the deflector door is positioned between a first closed position and a second open position. The material is substantially prevented from exiting through the discharge port when the deflector door is in the first position. The deflector door may further be positioned at a position between the first closed position and second open position to control a distance of the material discharged from the discharge port.

Abstract: This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.