Abstract: The present invention relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein Ring A, Ring B, R1—R16, n and p are defined herein. The novel nitrogen-linked benzisoxazole sulfonamide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in patients. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth, such as cancer, in patients.

Abstract: The present disclosure relates to the treatment of cancer and/or cancer-associated disease. Certain aspects relate to the treatment of an individual having cancer or cancer-associated disease by administering to the individual a combination therapy of a first therapeutic agent that is an EZH2 inhibitor, a second therapeutic agent that is a CDK inhibitor, and a third therapeutic agent that is a selective estrogen receptor degrader.

Abstract: A method includes the following operations: identifying a layer of a first layout based on a first violation generated on the layer; generating a metal density value associated with the layer; when the metal density value is larger than or equal to a preset value, classifying the first violation into a first class corresponding to routing congestions of the first layout; when the first violation is classified into the first class, assigning, to the first violation, a first operation of a plurality of first pre-stored operations corresponding to the first class; and performing the first operation to the first layout to generate a second layout.

Abstract: A transport mechanism of a server rack including a carrier plate, a server rack disposed and fixed onto a top surface of the carrier plate, and multiple supporting assemblies respectively stacked onto a bottom surface of the carrier plate is provided. Each of the supporting assemblies has at least one cushion member. The cushion member has at least one hollow portion, and an opening of the hollow portion is exposed to an environment. The stiffness of the cushion member is smaller than the stiffness of the carrier plate. A pallet structure is also provided.

Abstract: A computer-implemented method, system and computer program product for recommending join operations of relational data among different tables. Relationships between one or more pairs of columns of relational data for one or more pairs of tables are identified by determining the semantic similarity between each pair of columns of relational data. The data content join converge for each of the identified relationships in connection with joining the tables involved in such identified relationships is determined. Furthermore, a join strength (indication of the degree that the relational data in the paired columns match) is calculated for each of the identified relationships based on the semantic similarity and the data content join coverage for such identified relationships. Based on the calculated join strength as well as other factors, a combination optimization algorithm identifies the best join combinations of relational data of the tables among a set of tables.

Abstract: A fuel cell system includes: an anode gas intake path that is linked to a hydrogen circulation path to feed anode gas to an anode of a fuel cell; an anode gas discharge path linked to the anode; a cathode gas intake path for feeding cathode gas to a cathode of the fuel cell; a cathode gas discharge path linked to the cathode; a bypass flow path that links the hydrogen circulation path to the cathode gas intake path and/or the cathode gas discharge path; a circulating pump on the hydrogen circulation path; on-off valves on the anode gas intake path, the anode gas discharge path, and the bypass flow path; and a control device configured to control the on-off valves and the circulating pump. The control device is configured to cause the circulating pump to rotate in a normal or reverse direction selectively to discharge water or water vapor.

Abstract: A computer-implemented method, system and computer program product for recommending join operations of relational data among different tables. Relationships between one or more pairs of columns of relational data for one or more pairs of tables are identified by determining the semantic similarity between each pair of columns of relational data. The data content join converge for each of the identified relationships in connection with joining the tables involved in such identified relationships is determined. Furthermore, a join strength (indication of the degree that the relational data in the paired columns match) is calculated for each of the identified relationships based on the semantic similarity and the data content join coverage for such identified relationships. Based on the calculated join strength as well as other factors, a combination optimization algorithm identifies the best join combinations of relational data of the tables among a set of tables.

Abstract: A state determination device for a fuel cell stack includes: a fuel cell stack including at least one cell; and a control device that performs a state determination of the fuel cell stack by applying a measurement load waveform to the cell. The control device: generates a learning waveform; generates a measurement load waveform to be used this time by using, as reference values, membrane resistance, charge transfer resistance, and diffusion resistance in a relationship between a measurement frequency and an impedance that are generated based on the learning waveform; applies, to the cell, a waveform with an amplitude and frequencies that are calculated based on the measurement load waveform; and performs the state determination by measuring an alternating-current impedance by discharging, from the cell, a current or a voltage corresponding to a frequency of the measurement load waveform.

Abstract: Various embodiments include a data acquisition method including: generating a list of data points to be acquired from a field device; and performing the following separately for each data point. Parsing an address, and determining values of a region type, a DB offset, a byte offset and a bit offset in the address; using a first rule to calculate a sorting indicator of the data point according to the values determined; using a second predetermined rule to calculate a grouping indicator of the data point according to the determined values; sorting all of the data points according to the sorting indicators; dividing all of the sorted data points into multiple groups on the basis of the grouping indicator and a byte length of each data point and the length of a protocol data unit of the field device; and sending a data request for each group to the field device.

Abstract: A transport mechanism of a server rack including a carrier plate, a server rack disposed and fixed onto a top surface of the carrier plate, and multiple supporting assemblies respectively stacked onto a bottom surface of the carrier plate is provided. Each of the supporting assemblies has at least one cushion member. The cushion member has at least one hollow portion, and an opening of the hollow portion is exposed to an environment. The stiffness of the cushion member is smaller than the stiffness of the carrier plate. A pallet structure is also provided.

Abstract: A multi-cylindrical structure supply pipe includes at least three concentric pipes that couple a stationary fuel cell system that is stationary and an in-vehicle fuel cell system mounted on a fuel cell vehicle. The at least three concentric pipes include a hydrogen supply pipe, a liquid circulation pipe, and an electric wire pipe. The hydrogen supply pipe is configured to allow hydrogen gas to flow through the hydrogen supply pipe. The liquid circulation pipe surrounds an outer periphery of the hydrogen supply pipe. The liquid circulation pipe is configured to allow liquid to flow through the liquid circulation pipe outside the hydrogen supply pipe. The electric wire pipe surrounds an outer periphery of the liquid circulation pipe. The electric wire pipe is provided with one or more electric wires outside the liquid circulation pipe.

Abstract: A method for generating hydrogen from a mixture of nitrogen containing borane compound and active metal borohydride reactants uses a catalyst-free water vapor driven hydrothermolysis process. The method involves mechanically mixing a selected ratio of nitrogen containing borane compound such as ammonia borane and an active metal borohydride such as sodium borohydride to produce a mixture, combining the mixture with a water vapor source, and heating the mixture and water vapor source to a temperature within a near ambient temperature range of 30° C. to 104° C., until a product gas comprising hydrogen is released. The heating can be at a constant temperature or at increasing temperatures. Water vapor and impurities are removed from the product gas to produce purified hydrogen gas.

Abstract: An approach is disclosed that determines an amount of time before a webpage is ready to use by a user by performing various actions. The approach captures a recording of the webpage from an invocation of the webpage for a period of time sufficient to load completely load the webpage with the capturing resulting in sequenced image frames. An AI system provides a loading point in the sequenced image frames based on an analysis of the frames input to the trained AI system. Image diversity and saturation measurements are calculated on consecutive image frames from the sequenced image frames resulting in an image change analysis. Native webpage events and times are detected from webpage characteristics gathered from the captured digital recording. The amount of time is then calculated based on the loading point from the AI system, the image change analysis; and the webpage events and their corresponding times.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ring A, R1-R8, and n are defined herein. The novel benzisoxazole sulfonamide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in patients. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in patients.

Abstract: The hydrogen storage product comprises one or more reduced-graphene oxide layers functionalized with a boron species and decorated with an alkali or alkaline earth metal. Each layer of the structure further comprises boron-oxygen functional groups comprising oxygen atoms bonded to boron atoms. The hydrogen storage product has a composition suitable for physisorption of hydrogen molecule, and operates to reversibly store hydrogen under operating conditions of low pressure and ambient temperature.

Abstract: An approach is disclosed that determines an amount of time before a webpage is ready to use by a user by performing various actions. The approach captures a recording of the webpage from an invocation of the webpage for a period of time sufficient to load completely load the webpage with the capturing resulting in sequenced image frames. An AI system provides a loading point in the sequenced image frames based on an analysis of the frames input to the trained AI system. Image diversity and saturation measurements are calculated on consecutive image frames from the sequenced image frames resulting in an image change analysis. Native webpage events and times are detected from webpage characteristics gathered from the captured digital recording. The amount of time is then calculated based on the loading point from the AI system, the image change analysis; and the webpage events and their corresponding times.

Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.

Abstract: A method includes the following operations: identifying a layer of a first layout based on a first violation generated on the layer; generating a metal density value associated with the layer; when the metal density value is larger than or equal to a preset value, classifying the first violation into a first class corresponding to routing congestions of the first layout; when the first violation is classified into the first class, assigning, to the first violation, a first operation of a plurality of first pre-stored operations corresponding to the first class; and performing the first operation to the first layout to generate a second layout.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ring A, R1-R8, and n are defined herein. The novel benzisoxazole sulfonamide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in patients. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in patients.

Abstract: A method includes the following operations: receiving design rule violations of a first layout; classifying, according to first chip features of the first layout, a first violation of the design rule violations into a first class of predefined classes; generating a first vector array for at least one of the first chip features of the first layout, that is associated with the first violation; selecting, according to the first vector array, first operations from pre-stored operations; generating a second layout based on the first layout and the first operations.