Patents by Inventor Pei Pei

Pei Pei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10570121
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: February 25, 2020
    Assignee: Pfizer Inc.
    Inventors: Michael Raymond Collins, Robert Steven Kania, Robert Arnold Kumpf, Pei-Pei Kung, Daniel Tyler Richter, Scott Channing Sutton, Martin James Wythes
  • Patent number: 10519500
    Abstract: A method of preparing a crystalline copper-based coordination polymer comprises preparing a mixture of copper ions and a first quaternized carboxylate pyridyl ligand; adding a second polypyridyl ligand; and forming crystals of a copper-based coordination polymer therefrom. The crystalline copper-based coordination polymer is suitable for providing a sensing platform for detecting the presence of one or more target nucleic acid sequences such as viral RNA, in particular Dengue virus and/or Zika virus RNA with high selectivity and high specificity. A method of detecting at least a first target nucleic acid sequence, in particular from a viral RNA, in particular it is Flavivirus RNA, in a sample is also provided. Further provided is a kit including the crystalline copper-based coordination polymer and an oligonucleotide probe.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: December 31, 2019
    Assignees: MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY, SOUTHERN MEDICAL UNIVERSITY
    Inventors: Jin-Xiang Chen, Bao-Ping Xie, Gui-Hua Qiu, Pei-Pei Hu, Zhen Liang, Ye-Mei Liang, Bin Sun, Li-Ping Bai, Zhi-Hong Jiang
  • Publication number: 20190270737
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Application
    Filed: May 20, 2019
    Publication date: September 5, 2019
    Applicant: Pfizer Inc.
    Inventors: Aaron Craig Burns, Michael Raymond Collins, Samantha Elizabeth Greasley, Robert Louis Hoffman, Peter Qinhua Huang, Robert Steven Kania, Pei-Pei Kung, Maria Angelica Linton, Lakshmi Sourirajan Narasimhan, Paul Francis Richardson, Daniel Tyler Richter, Graham Smith
  • Patent number: 10296624
    Abstract: A method for curating documents, executed by a computer, includes detecting one or more themes in a document, identifying one or more user interests for a user, presenting a ranked list of the one or more themes to the user, and dynamically updating the ranked list based on user feedback. The ranked list may be ranked according to the one or more user interests. A computer program product and computer system corresponding to the above method are also disclosed herein.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: May 21, 2019
    Assignee: International Business Machines Corporation
    Inventors: Shuo Li, Yue Li, Zhao Wei Li, Pei Pei Liang, Jun Liu, Yun Ting Wang, Xin Ying Yang, Guang Ming Zhang, Zhi Hui Zhu
  • Patent number: 10296623
    Abstract: A method for curating documents, executed by a computer, includes detecting one or more themes in a document, identifying one or more user interests for a user, presenting a ranked list of the one or more themes to the user, and dynamically updating the ranked list based on user feedback. The ranked list may be ranked according to the one or more user interests. A computer program product and computer system corresponding to the above method are also disclosed herein.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: May 21, 2019
    Assignee: International Business Machines Corporation
    Inventors: Shuo Li, Yue Li, Zhao Wei Li, Pei Pei Liang, Jun Liu, Yun Ting Wang, Xin Ying Yang, Guang Ming Zhang, Zhi Hui Zhu
  • Patent number: 10246433
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, U, V, L, M, R5, m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: April 2, 2019
    Assignee: Pfizer Inc.
    Inventors: Martin Paul Edwards, Robert Arnold Kumpf, Pei-Pei Kung, Indrawan James McAlpine, Sacha Ninkovic, Eugene Yuanjin Rui, Scott Channing Sutton, John Howard Tatlock, Martin James Wythes, Luke Raymond Zehnder
  • Publication number: 20190040055
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Application
    Filed: October 11, 2018
    Publication date: February 7, 2019
    Applicant: Pfizer Inc.
    Inventors: Aaron Craig Burns, Michael Raymond Collins, Samantha Elizabeth Greasley, Robert Louis Hoffman, Peter Qinhua Huang, Robert Steven Kania, Pei-Pei Kung, Maria Angelica Linton, Lakshmi Sourirajan Narasimhan, Paul Francis Richardson, Daniel Tyler Richter, Graham Smith
  • Publication number: 20190040047
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Application
    Filed: October 10, 2018
    Publication date: February 7, 2019
    Applicant: Pfizer Inc.
    Inventors: Michael Raymond Collins, Robert Steven Kania, Robert Arnold Kumpf, Pei-Pei Kung, Daniel Tyler Richter, Scott Channing Sutton, Martin James Wythes
  • Publication number: 20180334713
    Abstract: A method of preparing a crystalline copper-based coordination polymer comprises preparing a mixture of copper ions and a first quaternized carboxylate pyridyl ligand; adding a second polypyridyl ligand; and forming crystals of a copper-based coordination polymer therefrom. The crystalline copper-based coordination polymer is suitable for providing a sensing platform for detecting the presence of one or more target nucleic acid sequences such as viral RNA, in particular Dengue virus and/or Zika virus RNA with high selectivity and high specificity. A method of detecting at least a first target nucleic acid sequence, in particular from a viral RNA, in particular it is Flavivirus RNA, in a sample is also provided. Further provided is a kit including the crystalline copper-based coordination polymer and an oligonucleotide probe.
    Type: Application
    Filed: May 22, 2017
    Publication date: November 22, 2018
    Inventors: Jin-Xiang Chen, Bao-Ping Xie, Gui-Hua Qiu, Pei-Pei Hu, Zhen Liang, Ye-Mei Liang, Bin Sun, Li-Ping Bai, Zhi-Hong Jiang
  • Patent number: 10125130
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: November 13, 2018
    Assignee: Pfizer Inc.
    Inventors: Aaron Craig Burns, Michael Raymond Collins, Samantha Elizabeth Greasley, Robert Louis Hoffman, Peter Qinhua Huang, Robert Steven Kania, Pei-Pei Kung, Maria Angelica Linton, Lakshmi Sourirajan Narasimhan, Paul Francis Richardson, Daniel Tyler Richter, Graham Smith
  • Publication number: 20180148441
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Application
    Filed: November 29, 2017
    Publication date: May 31, 2018
    Applicant: PFIZER INC.
    Inventors: Aaron Craig BURNS, Michael Raymond COLLINS, Samantha Elizabeth GREASLEY, Robert Louis Hoffman, Peter Qinhua HUANG, Robert Steven Kania, Pei-Pei KUNG, Maria Angelica LINTON, Lakshmi Sourirajan NARASIMHAN, Paul Francis RICHARDSON, Daniel Tyler RICHTER, Graham SMITH
  • Publication number: 20170298048
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Applicant: Pfizer Inc.
    Inventors: Michael Raymond Collins, Robert Steven Kania, Robert Arnold Kumpf, Pei-Pei Kung, Daniel Tyler Richter, Scott Channing Sutton, Martin James Wythes
  • Publication number: 20170277695
    Abstract: A method for curating documents, executed by a computer, includes detecting one or more themes in a document, identifying one or more user interests for a user, presenting a ranked list of the one or more themes to the user, and dynamically updating the ranked list based on user feedback. The ranked list may be ranked according to the one or more user interests. A computer program product and computer system corresponding to the above method are also disclosed herein.
    Type: Application
    Filed: June 12, 2017
    Publication date: September 28, 2017
    Inventors: Shuo Li, Yue Li, Zhao Wei Li, Pei Pei Liang, Jun Liu, Yun Ting Wang, Xin Ying Yang, Guang Ming Zhang, Zhi Hui Zhu
  • Publication number: 20170262129
    Abstract: According to an embodiment of the present disclosure, an electrical device may include a substrate, an electrical element, a first barrier structure and a gas barrier layer. The substrate includes an active region and a periphery region surrounding the active region. The electrical element is disposed in the active region. The first barrier structure is disposed in the periphery region and surrounds the electrical element, wherein the first barrier structure includes a first conductive layer. The gas barrier layer covers the electrical element and the first barrier structure.
    Type: Application
    Filed: August 12, 2016
    Publication date: September 14, 2017
    Applicant: Industrial Technology Research Institute
    Inventors: Wei-Yuan Cheng, Chih-Chia Chang, Ruo-Lan Chang, Pei-Pei Cheng, Chao-Wen Chen
  • Publication number: 20170233368
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, U, V, L, M, R5, m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Application
    Filed: May 3, 2017
    Publication date: August 17, 2017
    Applicant: Pfizer Inc.
    Inventors: Martin Paul EDWARDS, Robert Arnold KUMPF, Pei-Pei KUNG, lndrawan James MCALPINE, Sacha NINKOVIC, Eugene Yuanjin RUI, Scott Channing SUTTON, John Howard TATLOCK, Martin James WYTHES, Luke Raymond ZEHNDER
  • Publication number: 20170152239
    Abstract: This invention relates to compounds of general formula in which R1, R2, R6, U, V, W, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and salts, and to methods of using such compounds, salts and compositions.
    Type: Application
    Filed: February 6, 2017
    Publication date: June 1, 2017
    Applicant: Pfizer Inc.
    Inventors: Martin Paul EDWARDS, Robert Arnold KUMPF, Pei-Pei KUNG, Indrawan James MCALPINE, Eugene Yuanjin RUI, Scott Channing SUTTON, John Howard TATLOCK, Martin James WYTHES
  • Publication number: 20170124083
    Abstract: A method for curating documents, executed by a computer, includes detecting one or more themes in a document, identifying one or more user interests for a user, presenting a ranked list of the one or more themes to the user, and dynamically updating the ranked list based on user feedback. The ranked list may be ranked according to the one or more user interests. A computer program product and computer system corresponding to the above method are also disclosed herein.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 4, 2017
    Inventors: Shuo Li, Yue Li, Zhao Wei Li, Pei Pei Liang, Jun Liu, Yun Ting Wang, Xin Ying Yang, Guang Ming Zhang, Zhi Hui Zhu
  • Publication number: 20170050958
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Application
    Filed: April 17, 2015
    Publication date: February 23, 2017
    Applicant: PFIZER INC.
    Inventors: Aaron Craig BURNS, Michael Raymond COLLINS, Samantha Elizabeth GREASLEY, Robert Louis Hoffman, Peter Qinhua HUANG, Robert Steven Kania, Pei-Pei KUNG, Maria Angelica LINTON, Lakshmi Sourirajan NARASIMHAN, Paul Francis RICHARDSON, Daniel Tyler RICHTER, Graham SMITH
  • Publication number: 20160376254
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Application
    Filed: September 12, 2016
    Publication date: December 29, 2016
    Applicant: Pfizer Inc.
    Inventors: Michael Raymond COLLINS, Robert Steven Kania, Robert Arnold Kumpf, Pei-Pei Kung, Daniel Tyler Richter, Scott Channing Sutton, Martin James Wythes
  • Patent number: 9481666
    Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: November 1, 2016
    Assignee: PFIZER INC.
    Inventors: Robert Steven Kania, Robert Arnold Kumpf, Pei-Pei Kung, Scott Channing Sutton, Martin James Wythes