Abstract: The present invention pertains to a method for automatic sea lice monitoring in fish aquaculture, the method comprising submerging a camera (4) in a sea pen (300) comprising fish, using the camera to make an image of at least one of said fish, analysing the image to differentiate between individual sea lice present on the fish and the fish itself and assessing the number of sea lice present on the fish, wherein the camera is attached to a device (1, 10, 100) for guiding the salmon along an imaging track (5), the camera being directed to the track.

Abstract: The invention relates to a method for preparing a coupling product having the sequence Pq-Wv-His-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Y-Glu-Phe-Ile-Ala-Trp-Leu-Val-Z-Gly-Arg-Gly.

Abstract: A method for synthesizing a peptide having the sequence His-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Y-Glu-Phe-Ile-Ala-Trp-Leu-Val-Z-Gly-Arg-Gly is disclosed. The method includes enzymatically coupling: (a) a peptide C-terminal ester or thioester having a first peptide fragment with the sequence His-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-(thio)ester; and (b) a peptide nucleophile having an N-terminally unprotected amine having a second peptide fragment with the sequence H-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Y-Glu-Phe-Ile-Ala-Trp-Leu-Val-Z-Gly-Arg-Gly; wherein: X is Ala or an ?-amino-isobutyric acid (Aib) residue; Y is Lys, which Lys has a free side-chain ?-amino group or of which Lys the side-chain ?-amino group is protected with a protective group or of which Lys the side-chain ?-amino group is functionalized with an amino acid or another functional group; and Z is Arg or Lys.

Abstract: A closure assembly with a spout having a body with a seal portion and a tubular neck, and, a rotational plastic cap having a top wall, a downward depending skirt and opposite wing parts, extending in a vertical plane from the skirt over a wing part length. The top portion of the wing parts has a top protrusion extending from the base portion. The top protrusion extends substantially in and/or opposed to the opening direction of the cap such that the top portion of the wing parts extends along the wing part length over/outside the base portion thereof in a direction corresponding or opposed to the opening direction, such that, for a cross-section in a vertical plane of the opening direction, the surface area of the at least one top protrusion contributes at least equally to the inertial moment as the surface area of the base portion.

Abstract: Migration of formation solids in a wellbore is restrained by feeding a slurry, comprising water, a viscosifier, and a concentration of cement clinker particles, into the wellbore, and hydrating the clinker particles in the wellbore. The clinker particles are kept in suspension during the hydrating, and upon completion of the hydrating the hydrated clinker particles form a hardened cement consisting of a permeable structure of interconnected hydrated clinker particles. A layer of degradable lost circulation material (LCM) may be employed to separate the slurry with clinker particles from the formation surrounding the wellbore during hydrating of the clinker particles.

Abstract: The invention further relates to a process for the enzymatic synthesis of an (oligo)peptide. The invention relates to a method for designing an enzymatic synthesis process of an (oligo)peptide, comprising identifying two or more (oligo)peptide fragments of an (oligo)peptide, which fragments are (oligo)peptides suitable for preparing the (oligo)peptide by enzymatic condensation of the two or more peptide fragments using a ligase. The invention relates to a method for designing an enzymatic synthesis process of a cyclic (oligo)peptide, comprising identifying a non-cyclic (oligo)peptide from which the cyclic (oligo)peptide can be prepared by cyclisation, catalysed by a cyclase. The invention further relates to a process for the enzymatic synthesis of an (oligo)peptide.

Abstract: The invention relates to a method for preparing a coupling product having the sequence Pq-Wv-His-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Y-Glu-Phe-Ile-Ala-Trp-Leu-Val-Z-Gly-Arg-Gly.

Abstract: The present invention relates to a centrifugal fan comprising a fan housing with a radial outlet opening arranged in a radial peripheral wall thereof, a rotor arranged rotatably in the fan housing and provided close to an axial rotation axis thereof with a rotor inflow opening, wherein the fan housing is provided close to the rotation axis of the rotor with an axial inlet opening, and a tube part which extends in the fan housing from the radial outlet opening arranged in the radial peripheral wall and inward along the radial peripheral wall. The invention further relates to a heating device comprising a burner with a fuel mixture infeed opening, a centrifugal fan according to the invention, and wherein a fluid connection is provided between the fuel mixture infeed opening of the burner and the outlet opening of the centrifugal fan.

Abstract: In a closure assembly the cap is a quarter-turn cap and the bottom end of the skirt has a pair of diametrically opposed static cover portions separated from one another by a pair of diametrically opposed and open bottomed notches in the skirt. In each notch an indicator segment of the tamper-evident structure is located that is integrally molded to an upper notch rim by a non-frangible hinge, preferably a film hinge, and to each of the leading rim and the trailing rim via at least one respective frangible bridge.

Abstract: A closure assembly with a spout having a body with a seal portion and a tubular neck, and, a rotational plastic cap having a top wall, a downward depending skirt and opposite wing parts, extending in a vertical plane from the skirt over a wing part length. The top portion of the wing parts has a top protrusion extending from the base portion. The top protrusion extends substantially in and/or opposed to the opening direction of the cap such that the top portion of the wing parts extends along the wing part length over/outside the base portion thereof in a direction corresponding or opposed to the opening direction, such that, for a cross-section in a vertical plane of the opening direction, the surface area of the at least one top protrusion contributes at least equally to the inertial moment as the surface area of the base portion.

Abstract: A closure assembly with a spout having a body with a seal portion and a tubular neck, and, a rotational plastic cap having a top wall, a downward depending skirt and opposite wing parts, extending in a vertical plane from the skirt over a wing part length. The top portion of the wing parts has a top protrusion extending from the base portion. The top protrusion extends substantially in and/or opposed to the opening direction of the cap such that the top portion of the wing parts extends along the wing part length over/outside the base portion thereof in a direction corresponding or opposed to the opening direction, such that, for a cross-section in a vertical plane of the opening direction, the surface area of the at least one top protrusion contributes at least equally to the inertial moment as the surface area of the base portion.

Abstract: A manipulator system having a positioner having a primary rail, a first coupling linkage, and a second coupling linkage. The first coupling linkage couples the primary rail to a base and positions the primary rail along a first plane. The system has another positioner having a secondary rail, a third coupling linkage, and a fourth coupling linkage. The third coupling linkage couples the secondary rail to the base and positions the secondary rail along a second plane which is parallel to the first plane. A common link couples to the primary and secondary rails via linkages. Each of the second and fourth coupling linkages includes a joint for linear motion along the respective rail, and a revolute joint for relative pivoting between the respective rail and the common link. A position and orientation of the common link are adjustable by the joints and revolute joints.

Abstract: A device for mixing combustible gas and combustion air, hot water installation, and corresponding thermal mass flow sensor and method. The device includes an air line, a gas line with a control valve, a first measuring line connecting the air and gas lines, and a second measuring line connecting the first measuring line to the gas and/or air line, forming a three-way intersection. A thermal mass flow sensor includes first and second temperature sensors in the first measuring line, positioned respectively in a gas flow between the three-way intersection and the air line and in a gas flow between the three-way intersection and the gas line. A controller controls the control valve based on a difference, measured by the flow sensor, between mass flow rate of gas between the three-way intersection and the air line and mass flow rate of gas between the three-way intersection and the gas line.

Abstract: A method for synthesizing a peptide having the sequence His-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Y-Glu-Phe-Ile-Ala-Trp-Leu-Val-Z-Gly-Arg-Gly is disclosed. The method includes enzymatically coupling: (a) a peptide C-terminal ester or thioester having a first peptide fragment with the sequence His-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-(thio)ester; and (b) a peptide nucleophile having an N-terminally unprotected amine having a second peptide fragment with the sequence H-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Y-Glu-Phe-Ile-Ala-Trp-Leu-Val-Z-Gly-Arg-Gly; wherein: X is Ala or an ?-amino-isobutyric acid (Aib) residue; Y is Lys, which Lys has a free side-chain ?-amino group or of which Lys the side-chain ?-amino group is protected with a protective group or of which Lys the side-chain ?-amino group is functionalized with an amino acid or another functional group; and Z is Arg or Lys.

Abstract: The invention relates to a method and a device for determining in a heating appliance whether ignition of the mixture of fluid fuel and air has taken place, comprising the following steps of: applying an electrical ignition signal to a measuring circuit; filtering a combustion signal from the ignition signal; comparing the detected combustion signal to a predetermined pattern; and establishing that the anticipated combustion signal took place during a predetermined period of time.

Abstract: A domestic appliance has an operating element, the operating element comprising a carrier, at least one pressure sensor configured for detection of an operation of the operating element, and at least one light source. A control is configured to switch the light source on or off subject to a sensor signal coming from the pressure sensor. At least one light conductor is arranged close to the light source and is configured to conduct light from the light source to at least a side of the light conductor remote from the carrier. Provided on or close to the side of the light conductor remote from the carrier is a screen comprising at least one opaque part and at least one translucent part, which together form a symbol.

Abstract: The invention relates to a heat exchanger, comprising a hollow central body which is received in a housing and defines an inner channel for a first medium, wherein a space surrounding the central body in the housing defines at least one outer channel for a second medium, wherein the central body has on either side parts which protrude from a main plane thereof and are connected to mutually opposite parts of the housing and which bound the outer channel such that the outer channel has a meandering form substantially parallel to the main plane of the central body. The invention further relates to a method for forming such a heat exchanger, and to a method for use thereof.

Abstract: A method of monitoring a bone fracture in an individual. The method comprises the steps of: measuring a first parameter indicative of the load on said bone fracture; measuring a second parameter indicative of the activity level of said individual; obtaining a plurality of values for said first and second parameters; correlating said values to determine a measure of bone fracture condition; monitoring a change in said correlation over time; and determining a measure of the change in bone fracture condition over time. A bone fixation system implements this method of monitoring a bone fracture in an individual. The method and system provide a more accurate and reliable measure of bone fracture condition and of the progression of healing of the bone fracture.

Abstract: The invention relates to a subtilisin BPN? variant or homolog thereof, having the following mutations compared to subtilisin BPN? represented by SEQUENCE ID NO: 2 or a homolog sequence thereof:—a deletion of the amino acids corresponding to positions 75-83;—a mutation at the amino acid position corresponding to S221, the mutation corresponding to S221C or S221 selenocysteine, preferably S221C;—at least one further mutation selected from the group consisting of amino acid positions corresponding to F189W, F189Y, S33D, S33T, N218D, N218T, N218E, N62D, N62S, N62W, and N62Y; preferably a mutation at the amino acid position corresponding to P225; wherein the amino acid positions are defined according to the sequence of subtilisin BPN? represented by SEQUENCE ID NO: 2. The invention further relates to enzymatically synthesizing a peptide.

Abstract: In a closure assembly the cap (20) is a quarter-turn cap and the bottom end of the skirt has a pair of diametrically opposed static cover portions (23, 24) separated from one another by a pair of diametrically opposed and open bottomed notches (33, 34) in said skirt. In each notch an indicator segment (41, 42) of the tamper-evident structure is located that is integrally molded to an upper notch rim by a non-frangible hinge (43, 44), preferably a film hinge, and to each of said leading rim and said trailing rim via at least one respective frangible bridge (45, 46, 47, 48).