Abstract: A method of monitoring a bone fracture in an individual. The method comprises the steps of: measuring a first parameter indicative of the load on said bone fracture; measuring a second parameter indicative of the activity level of said individual; obtaining a plurality of values for said first and second parameters; correlating said values to determine a measure of bone fracture condition; monitoring a change in said correlation over time; and determining a measure of the change in bone fracture condition over time. A bone fixation system implements this method of monitoring a bone fracture in an individual. The method and system provide a more accurate and reliable measure of bone fracture condition and of the progression of healing of the bone fracture.

Abstract: The invention relates to a mixture supply system which is adapted for mounting in a hot water appliance and which is adapted to supply a combustible mixture to a burner of the hot water appliance, comprising a fuel feed for a fluid fuel, an oxidizer feed for a fluid oxidizer, a mixing chamber for mixing the fuel and the oxidizer in order to form the combustible mixture, a discharge for discharging the combustible mixture from the mixing chamber and a fan for urging the fuel and oxidizer from the respective feed to the mixing chamber, and urging the mixture therefrom to the discharge, wherein the fan is adapted to act directly on both the fuel and the oxidizer. The fan does not so much make use of an airflow with gas drawn in by a venturi, but gas is supplied separately to the fan.

Abstract: Methods and apparatus for providing a network attached storage system which does not require specialized hardware to operate. In one embodiment, a downloadable software package is provided via a web interface. After a user has downloaded and installed the software package, a sharable volume is created upon a host system. In one embodiment, the sharable volume is adapted to present the contents of one or more remote systems to the host system as a local file, drive, or directory. One or more processes resident in the host system are adapted to intercept a command interpretable by the host system and translate the command into one or more commands interpretable by at least one remote system. The one or more commands are then serviced by at least one remote system and a result set is generated. The result set may then be converted into a format interpretable by the host system and output accordingly.

Abstract: The present invention relates to a composition, such as a coating composition, comprising a peptide linked to a lubricant, wherein the peptide is cleavable by one or more proteinases present in tear fluid. The invention further relates to an ocular device comprising said composition, such as a preformed contact lens.

Abstract: The invention relates to a nucleic acid sequence encoding an itaconate transporting Major Facilitator Superfamily Transporter (MFST) gene sequence and the protein encoded thereby. Preferably said sequence is the nucleic acid that comprises the sequence of ATEG_09972.1 of Aspergillus terreus or homologues thereof. Overexpression of the protein enhances the production of itaconic acid in micro-organisms.

Abstract: A collapsible pouch (1) is provided with a closure assembly (10; 110; 210; 310; 410), which comprises a monolithic spout base and cap part (11; 111; 311) and a tubular inner part (30; 130; 230; 330; 430). The inner part comprises a fixation portion (31; 131; 331; 431) and a neck portion (32; 132; 232) and has been inserted into the spout base and cap part via the lower opening of the bore thereof in a pre-assembly operation prior to sealing of the pre-assembled closure assembly between the two walls (3, 4) of the pouch. The fixation portion is received and fixed in the bore of the spout base (12; 112; 212). The neck portion protrudes from the spout base into the cap cavity and extends to a mouth opening (34; 134) of the neck portion.

Abstract: Follow-up content items are determined for being played out when the current play-out of a content item has ended or is scheduled to end. The follow-up content items are determined, based on one or more bibliographic or semantic attributes of the item being played out and, on additional parameters such as the available bandwidth and the required data transfer rate. During the playing out of the content item, at least the first portions of the follow-up content items are retrieved and buffered in a buffer local to the equipment. Upon the playing-out of the content item being halted, the playing-out of the follow-up content items can be started right away from the buffer.

Abstract: The invention relates to a nucleic acid sequence encoding an Aspergillus mitochondrial tricarboxylic acid transporter that can be used in the production of itaconic acid in micro-organisms. Preferably said transporter protein is the protein encoded by the nucleic acid which is located on a chromosome segment of A. terreus that also harbors other genes involved in the itaconic acid biosynthesis and the lovastatin biosynthesis. Also, vectors, hosts and transformed micro-organisms are part of the invention.

Abstract: The invention relates to the use of a cytosolic citric acid synthase for the heterologous production of citrate outside the mitochondrion of a micro-organism or algae, wherein the protein is selected from A. niger An08g10920, An01g09940, An09g03570, or an ortholog of these genes. Such production is achieved by introducing the nucleic acid encoding such a protein into a suitable host cell. Preferably the protein is A. niger An08g10920, An01g09940, An09g03570 or an ortholog thereof, more particularly, wherein such an ortholog is chosen from the group of proteins listed in FIG. 9 and proteins having a percentage identity of 70%, more preferably 75%, more preferably 80%, more preferably 85%, more preferably 90%, more preferably 95%, more preferably 98%, more preferably 99% with An08g10920, An01g09940 or An09g03570.

Abstract: Methods to digest carbohydrates, especially lignocelluloses and hemicelluloses, using fungal proteins previously not recognized as having this activity are described.

Abstract: A method for detecting, in an audio signal including a stream of audio samples (y(n), (y?(n)), ticks in a noisy environment, comprises the steps of applying the signal to a coarse tick detection processor arranged to decide whether it is likely that the signal includes a tick and, only then, enabling a fine tick detection processor to decide, by more thorough processing the audio signal, whether the audio signal represents an audio tick.

Abstract: A method for providing pre-assembled and sterilized container closure assemblies that are each adapted to be secured onto a container including manufacturing pre-assembled container closure assemblies each adapted to be secured onto a container, injection molding a monolithic spout body of thermoplastic material, injection molding a manually removable rotational cap, securing the cap onto the neck of the spout body in a closed position of the cap, submerging each of the pre-assembled container closure assemblies in a bath of sterilizing liquid, and removing the container closure assemblies from the bath of sterilizing liquid, and allowing the sterilizing liquid to drain. A pre-assembled container closure assembly adapted to be secured onto a container is also disclosed.

Abstract: A pre-assembled container closure assembly (1) has a plastic spout body (2) with a tubular neck (4) delimiting a product passage (6) that extends to a mouth opening (8) of the neck. A rotational cap (30) is secured in closed position on the neck. The cap has a cap body including a top wall (31) and a skirt (32). The cap body further includes an annular inner sealing ring (40) depending from the top wall. The inside of the neck is provided with an inward tapering annular guide surface (15) that is contacted by the inner sealing ring when the cap is secured onto the spout body and then causes an elastic deformation of the inner sealing ring and/or the neck.

Abstract: Methods and systems for enabling content distribution from a first device to a second device are disclosed. A first device is configured to receive content and computer program script from a content source. The computer program script enables a content owner to define permissions that control the use and access of the content. The computer program script or a derivation thereof is provided from the first device to a second device, wherein said second device is communicably connected to the first device. On the basis of the computer program script, a template is generated by the second device for presenting the content. The second device transmits a request for the content and the content is retrieved from the first device in accordance with the permissions.

Abstract: A method is provided for producing a dehydrated biopolymer powder, said method comprising the successive steps of: a) providing a filter cake comprising biopolymer material and 30 to 60 wt. % of water; b) contacting said filter cake with a pressurized gas to extract water from the filter cake, said pressurized gas having a pressure and a temperature below the critical point of the gas; c) separating water-containing pressurized gas from the dehydrated filter cake; and d) collecting a dehydrated biopolymer powder wherein the pressurized gas has a pressure of at least 0.6 MPa (6 bar) and up to 6 MPa (60 bar), and a temperature of 10 to 40° C.

Abstract: A walking-trainer device for persons with a walking disorder to relearn walking has a movable tread surface and a display unit for displaying target indications of the corresponding and consecutive foot positions for movements made by a person walking on the tread surface. The target indications have the form of a number of consecutive patterns located above a target surface at the height of and in the longitudinal direction of the tread surface moving in the direction of the person, which visibly move from a distance of between 0.5 m and 0.5 m, preferably between 15 m and 5 m and more preferably between 0.7 m and 2.5 m, from the target surface in the direction of and over the tread surface up to the feet of the person. The speed of movement of the patterns is substantially equal to the speed of movement of the tread surface.

Abstract: Disclosed herein are a system, method, and computer program product for updating a scene model (230) used for object detection in a video sequence by defining a relationship between a pair of mode models relating to different visual elements of said scene model (230). The method includes the steps of: determining whether the pair of mode models have a temporal correlation with each other, dependent upon a predetermined criterion (745); determining a classification of each mode model in the pair of mode models (740); modifying the relationship between the pair of mode models, dependent upon the determination of the temporal correlation and the determination of the classification (760); and updating the scene model based upon the modified relationship (770).

Abstract: A pre-assembled container closure assembly (1) has a plastic spout body (2) with a tubular neck (4) delimiting a product passage (6) that extends to a mouth opening (8) of the neck. A rotational cap (30) is secured in closed position on the neck. The cap has a cap body including a top wall (31)and a skirt (32). The cap body further includes an annular inner sealing ring (40) depending from the top wall. The inside of the neck is provided with an inward tapering annular guide surface (15) that is contacted by the inner sealing ring when the cap is secured onto the spout body and then causes an elastic deformation of the inner sealing ring and/or the neck.

Abstract: Method for enzymatically synthesising an oligopeptide, comprising the coupling of an (optionally N-protected) protected oligopeptide ester with an (optionally C-protected) protected oligopeptide nucleophile in an organic solvent or an organic solvent mixture having a water content of 0.1 vol % or less, by a subtilisin in any possible form.

Abstract: A closure assembly comprises an article (1) forming a tubular neck (2) around a product passage (3) in said article. The neck forms a mouth at a top end of said product passage. The assembly further comprises a rotational cap (20) that is injection molded of plastic material and that is secured on or to be secured on said neck of the article. The cap seals the product passage in closed position of the cap on said neck, and the cap—for removal of the cap from the neck of the article by a user to open the product passage—is adapted to be manually rotated from the closed position in an opening direction.