Abstract: A method for delivering an audio and/or video content using adaptive streaming to a terminal, the audio and/or video content being segmented into data segments available in various representations with respective audio and/or video qualities, the representations being time-aligned per segment, the segments being further divided into chunks, a controller selects, from a set of candidate caching platforms, the caching platform to be used to deliver the audio and/or video content to the terminal, as a function of a minimum burst transfer duration compared with the chunk duration as defined by an origin server providing the audio and/or video content. The controller redirects the terminal to the selected platform for further delivery of the audio and/or video content in the form bursts of chunks in response to requests for segments.

Abstract: The present invention relates to the following compounds wherein the integers are as defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of tuberculosis.

Abstract: Systems and methods for non-invasive blood pressure measurement are disclosed. In some embodiments, a system comprises a wearable member configured to generate first and second signals, and a blood pressure calculation system. The blood pressure calculation system a pre-processing module configured to filter noise from the signals, and a wave selection module configured to identify subsets of waves of the signals, a feature extraction module configured to generate sets of feature vectors form the subsets of waves, and a blood pressure processing module configured to calculate an arterial blood pressure value based on the sets of feature vectors and an empirical blood pressure calculation model, the empirical blood pressure calculation model configured to receive the sets of feature vectors as input values. The blood pressure calculation system further includes a communication module configured to provide a message including or being based on the arterial blood pressure value.

Abstract: A method for manufacturing an integrally formed bladed disk of a turbomachine, includes manufacturing a plurality of blades, the blades including a root and a profiled portion; and spark plasma sintering the blades with a metal powder, the blades being angularly distributed over a contour of an annular spark plasma sintering mold, the root of the blades being embedded into the metal powder, the profiled portion of the blades protruding from the metal powder radially outwardly.

Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: Aspects of the present invention relate to methods for characterizing a multi-layered tire tread. In one example, a method comprises providing a first rubber composition having a first refractive index and providing a second rubber composition having a second refractive index. The method further comprises determining a difference between the first refractive index and the second refractive index and comparing the difference to a threshold refractive index. In addition, the method comprises adding a refractive index modifier to the first rubber composition and/or second rubber composition in case the comparison provides that the difference is lower than the threshold refractive index, so that the difference is greater than, or equal to, the threshold refractive index.

Abstract: A method for obtaining a product made of titanium alloy or a titanium-aluminum intermetallic compound by plasma torch melting, the alloy having an oriented structure, the method including heating the molten alloy surface in a casting ring with a plasma torch; cooling a cold zone of the casting ring over a length L1, the cooling forming a semi-solid crown of alloy; heating a hot zone of the casting ring over a length L2, thereby forming a solidification front, the flatness of which relative to a plane perpendicular to a drawing direction is less than 10°; and drawing the solidified alloy at a speed of more than 10?4 m/s in the drawing direction. The present disclosure also relates to a plant having one or more devices for implementing the method.

Abstract: A battery module can include multiple battery cells, multiple cell tubes, and a first plate. The multiple cell tubes can accommodate the multiple battery cells within the plurality of cell tubes so that individual of the plurality of battery cells are positioned within individual of the plurality of cell tubes. Each battery cell can have a first electric pole and a second electric pole. The first plate can include a printed circuit board. The printed circuit board can include a first conductive layer and an isolating layer. The isolating layer can include at least one blind hole for wire-bonding the conductive layer to one of the battery cells.

Abstract: Aspects of the present invention relate to a tire tread production line and a method for manufacturing a tire tread. The production line comprises a coextruder, a THz sensor and a controller operatively connected to the coextruder and to the THz sensor. The THz sensor is configured to irradiate the multi-layer tire tread extrudate with THz electromagnetic radiation, and receive a response of the multi-layer tire tread extrudate to the THz electromagnetic radiation. The controller is configured to operate the coextruder based on the response of the multi-layer tire tread extrudate to the THz electromagnetic radiation.

Abstract: The invention relates to a turbomachine rotary-fan blade having a predetermined breaking zone, which extends from the upstream edge along a given length and from the blade-tip edge over a given height. According to the invention, the body is made of a composite material comprising a fibre reinforcement obtained by three-dimensional weaving of warp and weft strands, and a resin matrix in which the fibre reinforcement is embedded, and has, in or in the vicinity of the zone, a discontinuity of at least some of the strands, configured such that the zone partially detaches when there is tangential friction in the thickness direction against the blade-tip edge, the height being less than 3% of the aerodynamic stream height of the blade.

Abstract: Blower vane for an aircraft turbine engine, the vane comprising a blade connected to a root, the vane being made of a woven fibre-based composite material embedded in a polymeric resin, the vane further comprising a medium for identifying the vane, which is a radio-identification medium, the blower vane being characterised in that it comprises at least a first portion the fibres of which are only electrically conductive fibres, and at least a second portion the fibres of which are formed by a mixture of electrically conductive fibres and non-electrically conductive fibres, and in that the identification medium is located in or on the second portion.

Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to the following compounds wherein the integers are as defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of tuberculosis.

Abstract: Disclosed herein are compounds of Formula I: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.

Abstract: A casting ring having a first section made of a heat-conductive material and a second section made of a MAX phase alloy material, and a method for obtaining a product made of titanium alloy or a titanium-aluminum intermetallic compound by plasma torch melting, the alloy having an oriented structure, the method including heating the molten alloy surface in the casting ring with a plasma torch; cooling a cold zone of the casting ring over a length L1, the cooling forming a semi-solid crown of alloy; heating a hot zone of the casting ring over a length L2, thereby forming a solidification front, the flatness of which relative to a plane perpendicular to a drawing direction is less than 10°; and drawing the solidified alloy at a speed of more than 10?4 m/s in the drawing direction.

Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: A method for manufacturing a turbine engine vane a root connected to a blade extending in a longitudinal direction includes the steps of providing a root; and providing mold with a first cavity and a second cavity that together define a recess in which the vane is formed. The recess includes a first space in which the blade is formed and a second space in which the root (1), c) is formed. The method further includes the steps of providing aluminum strips; positioning a fibrous reinforcement; arranging the vane root in the second space; and injecting a foam comprising aluminum or injecting an aluminum alloy into the first space of the recess of the mold such that the foam impregnates the fibrous reinforcement.