Patents by Inventor Pierre Jean

Pierre Jean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Turbojet bearing support produced by additive manufacturing
    Patent number: 11585236
    Abstract: A bearing support designed to be secured to a stationary turbojet element for supporting a journal, including a cone which widens from a central portion for supporting the journal to a portion for securing to the stationary element, a cylindrical body extending the portion for securing to the stationary element while surrounding the cone, an upstream skirt carried by the cone for defining an upstream enclosure for the central portion, and at least one downstream revolution element carried by the cone for defining a downstream enclosure for the central portion. The bearing support can be made as a single part produced by additive manufacturing.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: February 21, 2023
    Assignee: SAFRAN AIRCRAFT ENGINES
    Inventors: Dimitri Daniel Gabriel Marquie, Adrien Jacques Philippe Fabre, Frédéric Patard, Pierre Jean-Baptiste Metge
  • BICYCLIC COMPOUNDS
    Publication number: 20230051483
    Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 15, 2022
    Publication date: February 16, 2023
    Inventors: Sandrine Vendeville, Pierre Jean-Marie Bernard Raboisson, David McGowan, Yannick Debing
  • Synthetic speech processing
    Patent number: 11574624
    Abstract: A speech-processing system receives input data representing text. An input encoder processes the input data to determine first embedding data representing the text. A local attention encoder processes a subset of the first embedding data in accordance with a predicted size to determine second embedding data. An attention encoder processes the second embedding data to determine third embedding data. A decoder processes the third embedding data to determine audio data corresponding to the text.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: February 7, 2023
    Assignee: Amazon Technologies, Inc.
    Inventors: Arnaud Vincent Pierre Yves Joly, Panagiota Karanasou, Alexis Pierre Jean-Baptiste Moinet, Thomas Renaud Drugman, Sri Vishnu Kumar Karlapati, Syed Ammar Abbas, Simon Slangen
  • METHODS AND COMPOSITIONS FOR TARGETING PD-L1
    Publication number: 20230031213
    Abstract: The present disclosure related to compounds that can be useful as inhibitors of PD-1, PD-L1 or the PD-1/PD-L1 interaction. Also disclosed herein are pharmaceutical compositions of that can include a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and uses of or methods of using a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for the treatment of PD-L1 related diseases including but not limited to liver diseases, cancer, hepatocellular carcinoma, viral diseases, or hepatitis B.
    Type: Application
    Filed: June 15, 2022
    Publication date: February 2, 2023
    Inventors: Tongfei Wu, Pierre Jean-Marie Bernard Raboisson, Francois Gonzalvez, Antitsa Dimitrova Stoycheva, Cheng Liu, Jerome Deval, David McGowan
  • Method for identifying by mass spectrometry an unknown microorganism subgroup from a set of reference subgroups
    Patent number: 11562165
    Abstract: A method for identifying by mass spectrometry an unknown microorganism subgroup among a set of reference subgroups, including a step of constructing one knowledgebase and one classifying model per associated subgroup on the basis of the acquisition of at least one set of learning spectra of microorganisms identified as belonging to the subgroups of a group and including: constructing an adjusting model allowing mass-to-charge offsets of the acquired spectra to be corrected on the basis of reference masses-to-charges that are common to the various subgroups; adjusting the masses-to-charges of all of the lists of peaks of the learning spectra and constructing one classifying model per subgroup and the associated knowledgebase on the basis of the adjusted learning spectra.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: January 24, 2023
    Assignee: BIOMERIEUX
    Inventors: Maud Arsac, Pierre-Jean Cotte-Pattat, Victoria Girard, Valérie Monnin
  • Antibacterial Compounds
    Publication number: 20230014173
    Abstract: The present invention relates to the following compounds wherein the integers are as defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of tuberculosis.
    Type: Application
    Filed: September 17, 2021
    Publication date: January 19, 2023
    Applicant: Janssen Sciences Ireland UC
    Inventors: Jérôme Émile Georges Guillemont, Magali Madeleine Simone Motte, Pierre Jean-Marie Bernard Rabiosson, Abdellah Tahri
  • SOLUTION FOR MANUFACTURING A ONE-PIECE BLADED DISC
    Publication number: 20230017699
    Abstract: A method for manufacturing an integrally formed bladed disk of a turbomachine, includes manufacturing a plurality of blades, the blades including a root and a profiled portion; and spark plasma sintering the blades with a metal powder, the blades being angularly distributed over a contour of an annular spark plasma sintering mold, the root of the blades being embedded into the metal powder, the profiled portion of the blades protruding from the metal powder radially outwardly.
    Type: Application
    Filed: December 10, 2020
    Publication date: January 19, 2023
    Inventor: Pierre Jean SALLOT
  • MACROCYCLIC FLU ENDONUCLEASE INHIBITORS
    Publication number: 20230002409
    Abstract: The present invention relates to macrocyclic pyridotriazine derivatives and the prodrugs thereof, and the pharmaceutically acceptable salts, solvates or polymorph thereof, and the use of such compounds as a medicament, in particular in the prevention and/or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, and to the compositions or preparations for use as a medicament, more preferably for the prevention or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family.
    Type: Application
    Filed: March 15, 2022
    Publication date: January 5, 2023
    Inventors: Robert Than HENDRICKS, Antitsa Dimitrova STOYCHEVA, Jean-François BONFANTI, Pierre Jean-Marie Bernard RABOISSON, Jérôme Michel Claude FORTIN, Guillaume Jean Maurice MERCEY
  • METHODS AND COMPOSITIONS FOR TARGETING PD-L1
    Publication number: 20230002413
    Abstract: The present disclosure related to compounds that can be useful as inhibitors of PD-1, PD-L1 or the PD-1/PD-L1 interaction. Also disclosed herein are pharmaceutical compositions of that can include a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and uses of or methods of using a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for the treatment of PD-L1 related diseases including but not limited to liver diseases, cancer, hepatocellular carcinoma, viral diseases, or hepatitis B.
    Type: Application
    Filed: May 19, 2021
    Publication date: January 5, 2023
    Inventors: Tongfei Wu, Pierre Jean-Marie Bernard Raboisson, Antitsa Dimitrova Stoycheva, Francois Gonzalvez, Jerome Deval, Cheng Liu
  • METHOD FOR MANUFACTURING A COMPOSITE TURBOMACHINE BLADED DISK (BLISK) WITH CERAMIC REINFORCEMENT
    Publication number: 20230001480
    Abstract: A method for manufacturing a metal bladed wheel of a turbomachine reinforced by an insert made of metal matrix composite material, includes winding the ceramic fibers around a mandrel in order to form the insert, the ceramic fibers being surrounded by a material constituting the matrix; and spark plasma sintering the insert with a powder of metal constituting the bladed wheel to be manufactured.
    Type: Application
    Filed: December 10, 2020
    Publication date: January 5, 2023
    Inventors: Pierre Jean SALLOT, Jean-Michel Patrick Maurice FRANCHET
  • Pyrimidine derivatives for the treatment of viral infections
    Patent number: 11541050
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: January 3, 2023
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: David Mc Gowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrechts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jaromir Vlach
  • ELEMENT FOR DISTRIBUTING A COOLING FLUID AND ASSOCIATED TURBINE RING ASSEMBLY
    Publication number: 20220412226
    Abstract: A distribution element intended to be fixed to a support structure for supplying cooling fluid to a wall to be cooled facing the distribution element, the distribution element including a body defining a cooling fluid distribution internal volume and a multi-perforated plate which delimits the internal volume and includes a plurality of outlet through-perforations which put the cooling fluid distribution internal volume into communication with the wall to be cooled, the distribution element including an inlet orifice opening into the cooling fluid distribution internal volume, wherein for directing the cooling fluid from the inlet orifice to the plurality of outlet through-perforations the cooling fluid distribution internal volume includes directional fins.
    Type: Application
    Filed: May 5, 2022
    Publication date: December 29, 2022
    Inventors: Pierre Jean-Baptiste METGE, Sébastien Serge Francis CONGRATEL, Lucien Henri Jacques QUENNEHEN
  • METHOD FOR HOLDING A PART BLANK BY FLUID EXPANSION IN AN ADDITIVELY MANUFACTURED HOLDING PORTION
    Publication number: 20220395907
    Abstract: A method for holding a part blank inside a holding assembly. The holding assembly includes a first holding portion. The first holding portion includes an inner cavity containing a fluid. The part blank and the first holding portion are at least partially manufactured by additive manufacturing. The holding method includes a heating of the holding assembly and the part blank to deform the first holding portion by fluid expansion in the inner cavity and to reduce a gap between the part blank and the holding assembly by expansion of the first holding portion in relation to the part blank.
    Type: Application
    Filed: October 20, 2020
    Publication date: December 15, 2022
    Inventors: Guilhem Kevin COMBES, Sébastien Vincent François DREANO, Pierre Jean-Baptiste METGE
  • DIRECTING APPARATUS FOR ORIENTING AN ARC OF AN ARC WELDING DEVICE FOR ARC WELDING USING A MAGNETICALLY MOVED ARC, AND USE OF THE DIRECTING APPARATUS
    Publication number: 20220388085
    Abstract: A directing apparatus for orienting an arc of an arc welding device for arc welding, in particular for TIG welding, using a magnetically moved arc, comprising: a retaining device having an opening for receiving a welding head of the arc welding device; one or more solenoid coils for forming a magnetic field for deflecting an arc generated by a welding device in the opening; and at least two bent pole shoes comprising at least two legs for focusing the magnetic field, a first of the legs of each pole shoe being affixed to the retaining device and/or to the solenoid coil and a second of the legs being oriented at an angle of less than 130° to the first leg.
    Type: Application
    Filed: November 9, 2020
    Publication date: December 8, 2022
    Inventors: Lüder Bosse, Simon Mariager, Pierre-Jean Ober, Werner Wohlgemuth
  • TURBOMACHINE ROTARY FAN BLADE, FAN, AND TURBOMACHINE PROVIDED THEREWITH
    Publication number: 20220381148
    Abstract: The invention relates to a turbomachine rotary-fan blade having a predetermined breaking zone, which extends from the upstream edge along a given length and from the blade-tip edge over a given height. According to the invention, the body is made of a composite material comprising a fibre reinforcement obtained by three-dimensional weaving of warp and weft strands, and a resin matrix in which the fibre reinforcement is embedded, and has, in or in the vicinity of the zone, a discontinuity of at least some of the strands, configured such that the zone partially detaches when there is tangential friction in the thickness direction against the blade-tip edge, the height being less than 3% of the aerodynamic stream height of the blade.
    Type: Application
    Filed: November 18, 2020
    Publication date: December 1, 2022
    Applicant: SAFRAN AIRCRAFT ENGINES
    Inventors: Guillaume Pascal Jean-Charles GONDRE, Thomas Alain DE GAILLARD, Pierre Jean FAIVRE D'ARCIER
  • Cycloalkyl substituted pyrazolopyrimidines having activity against RSV
    Patent number: 11491157
    Abstract: The invention concerns compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection. (Formula I).
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: November 8, 2022
    Assignee: Janssen Sciences Ireland Unlimited Company Co Cork, IE
    Inventors: David Francis Alain Lançois, Jérôme Émile Georges Guillemont, Pierre Jean-Marie Bernard Raboisson, Dirk André Emmy Roymans, Peter Rigaux, Antoine Benjamin Michaut
  • FUSED HETEROCYCLIC DERIVATIVES
    Publication number: 20220348592
    Abstract: The application describes fused heterocycle derivative compounds, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases associated with HBV infection.
    Type: Application
    Filed: May 27, 2020
    Publication date: November 3, 2022
    Inventors: Sandrine Celine GROSSE, Scott D. KUDUK, Lindsey Graham DERATT, Koen VANDYCK, Pierre Jean-Marien Bernard RABOISSON, Serge Maria Aloysius PIETERS, Bart Rudolf Romanie KESTELEYN, Wim Gaston VERSCHUEREN, Jan Martin BERKE, Morgan Charles R. LECOMTE, Carolina MARTINEZ LAMENCA, Tim Hugo Maria JONCKERS, Gang DENG, Yimin JIANG, Yanping XU, Zhangling CHENG, Lili HU
  • SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS
    Publication number: 20220340522
    Abstract: The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 27, 2022
    Applicants: Janssen Pharmaceuticals, Inc., Katholieke Universiteit Leuven
    Inventors: Jean-François Bonfanti, Bart Rudolf Romanie Kesteleyn, Dorothée Alice Marie-Eve Bardiot, Arnaud Didier M Marchand, Erwin Coesemans, Jérôme Michel Claude Fortin, Guillaume Jean Maurice Mercey, Pierre Jean-Marie Bernard Raboisson
  • COATED PART COMPRISING A PROTECTIVE COATING BASED ON MAX PHASES
    Publication number: 20220325417
    Abstract: A coated part includes a metallic substrate, a thermal barrier comprising a ceramic material and covering the metallic substrate, wherein the coated part further includes a protective coating covering the thermal barrier, the protective coating including, in a first region, a first MAX phase, denoted PZ2, of formula (ZrxTi1-x,)2AlC or a first MAX phase, denoted PC2, of formula (CrxTi1-x,)2AlC with x non-zero and less than or equal to 1 in the MAX phases PZ2 and PC2, and the protective coating includes, in a second region covering the first region, a second MAX phase of formula Ti2AlC.
    Type: Application
    Filed: August 28, 2020
    Publication date: October 13, 2022
    Inventors: Aurélien JOULIA, Pierre Jean SALLOT
  • Heterocyclic compounds
    Patent number: 11464783
    Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating diseases and/or conditions with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: October 11, 2022
    Assignee: Aligos Therapeutics, Inc.
    Inventors: Sandrine Vendeville, Pierre Jean-Marie Bernard Raboisson