Abstract: Complex concentrated alloys include five or more elements, at least one of which is ruthenium. Example complex concentrated alloys can include nickel and chromium, iron, ruthenium, molybdenum, and/or tungsten. Example complex concentrated alloys have single phase microstructure of face centered cubic (FCC) and can be homogenous. Example complex concentrated alloys can exhibit improved corrosion resistance.

Abstract: The disclosure is directed to an ex vivo cell culture system and methods of using the cell culture system to identify potential therapeutic agents for the treatment of leukemia or lymphoma, such as chronic lymphocytic leukemia (CLL). The ex vivo culture system comprises (a) a first cell culture comprising bone marrow stromal cells (BMSC) which express one or more exogenous cell signaling molecules; (b) a second cell culture comprising leukemia or lymphoma cells isolated from a human; and optionally (c) one or more soluble cell signaling molecules.

Abstract: An online system receives an advertisement (“ad”) request identifying an application, one or more items for use within the application, ad content, and a prompt for purchasing one or more of the items. The prompt for purchasing an item comprises text or image data describing the purchasing and instructions that, when executed by a client device, request payment information from a user accessing the prompt. When the ad content is presented to a user, the prompt is also presented. When the user interacts with the prompt, payment information is requested and communicated to a third party system associated with the application. The ad content and prompt may be presented to the user within a feed of content items provided to the user by the online system.

Abstract: Complex concentrated alloys include five or more elements, at least one of which is ruthenium. Example complex concentrated alloys can include nickel and chromium, iron, ruthenium, molybdenum, and/or tungsten. Example complex concentrated alloys have single phase microstructure of face centered cubic (FCC) and can be homogenous. Example complex concentrated alloys can exhibit improved corrosion resistance.

Abstract: An online system receives an advertisement (“ad”) request identifying an application, one or more items for use within the application, ad content, and a prompt for purchasing one or more of the items. The prompt for purchasing an item comprises text or image data describing the purchasing and instructions that, when executed by a client device, request payment information from a user accessing the prompt. When the ad content is presented to a user, the prompt is also presented. When the user interacts with the prompt, payment information is requested and communicated to a third party system associated with the application. The ad content and prompt may be presented to the user within a feed of content items provided to the user by the online system.

Abstract: Activity level of memory pages is classified in virtual machine environment, so that processes such as live VM migration and checkpointing, among others, can be carried out more efficiently. The method includes the steps of scanning page table entries of hypervisor-managed page tables continuously over repeating scan periods to determine whether memory pages have been accessed or not, and for each memory page, determining an activity level of the memory page based on whether the memory page has been accessed or not since a prior scan and storing the activity level of the memory page. The activity level of the memory page may be represented by one or more bits of its page table entry and may be classified as having at least two states ranging from hot to cold.

Abstract: The present disclosure relates to a laminate for making a molded article comprising at least one fiber reinforcement impregnated with a resin matrix as a first layer and a foam as a second layer. The foam can be laminated to the first layer using a nanocomposite adhesive. The laminates can be easily molded using bagging mold techniques. The resulting molded devices have uses in biomedical, health care and sport protective devices. Due to the improved strength of material, it is possible to drill holes into the device shell allowing for improved ventilation.

Abstract: Multiple search indexes can be served from a common set of resources. Instead of requiring a processor to be dedicated to serving a single search index, a processor can provide responsive documents for search queries that are based on different ranking algorithms and/or different sets of documents.

Abstract: Activity level of memory pages is repeatedly classified in a virtual machine environment, so that live VM migration can be carried out more efficiently. The time intervals upon which the activity level of the memory pages are repeatedly classified can be dynamically adjusted to better align its performance with the live VM migration process.

Abstract: Embodiments of a vending machine are disclosed that can comprise one or more horizontally oriented shelves for supporting products to be vended, a plurality of vertically oriented dividers coupled to the shelves, a plurality of location markers located on the dividers and/or on the shelves, and an optical recognition module configured to optically recognize the location markers and to determine positions of the location markers and products relative to the shelves. In some embodiments, the optical recognition module can recognize the products by comparing images of the products to stored product images.

Abstract: Embodiments of a vending machine are disclosed that can comprise one or more horizontally oriented shelves for supporting products to be vended, a plurality of vertically oriented dividers coupled to the shelves, a plurality of location markers located on the dividers and/or on the shelves, and an optical recognition module configured to optically recognize the location markers and to determine positions of the location markers and products relative to the shelves. In some embodiments, the optical recognition module can recognize the products by comparing images of the products to stored product images.

Abstract: Multiple search indexes can be served from a common set of resources. Instead of requiring a processor to be dedicated to serving a single search index, a processor can provide responsive documents for search queries that are based on different ranking algorithms and/or different sets of documents.

Abstract: A provisioning system is described for dynamically and automatically allocating index server resources to different respective uses. For example, the provisioning system can allocate index server resources among different search-related production uses, different analysis-related uses, different testing-related uses, and so on. In one case, the provisioning system includes an allocation manager module that receives information that has a bearing on the allocation of index server resources. Based on this information, the allocation manager module determines an allocation of index server resources and sends instructions to an indexing system to carry out the allocation. In one case, the indexing system respond to the instructions by allocating rows of index server resources to different partner entities which have requested index server resources. Each row can also implement custom index information and/or custom processing functionality for use by particular partner entities.

Abstract: Activity level of memory pages is classified in virtual machine environment, so that processes such as live VM migration and checkpointing, among others, can be carried out more efficiently. The method includes the steps of scanning page table entries of hypervisor-managed page tables continuously over repeating scan periods to determine whether memory pages have been accessed or not, and for each memory page, determining an activity level of the memory page based on whether the memory page has been accessed or not since a prior scan and storing the activity level of the memory page. The activity level of the memory page may be represented by one or more bits of its page table entry and may be classified as having at least two states ranging from hot to cold.

Abstract: The present invention is directed to polynucleotides encoding polypeptides associated with the development of rheumatoid arthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of rheumatoid arthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.

Abstract: The present invention is directed to polynucleotides encoding polypeptides associated with the development of rheumatoid arthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of rheumatoid arthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.

Abstract: The present invention is directed to polynucleotides encoding polypeptides associated with the development of rheumatoid arthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of rheumatoid arthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.

Abstract: The present invention is directed to polynucleotides encoding polypeptides associated with the development of rheumatoid arthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of rheumatoid arthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.

Abstract: The present invention is directed to polynucleotides encoding polypeptides associated with the development of osteoarthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of osteoarthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.

Abstract: The present invention is directed to polynucleotides encoding polypeptides associated with the development of rheumatoid arthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of rheumatoid arthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.