Abstract: LIDAR measurement systems employing a multiple channel, GaN based illumination driver integrated circuit (IC) are described herein. In one aspect, the multiple channel, GaN based illumination driver IC selectively couples each illumination source associated with each measurement channel to a source of electrical power to generate a measurement pulse of illumination light. In one aspect, each pulse trigger signal associated with each measurement channel is received on a separate node of the IC. In another aspect, additional control signals are received on separate nodes of the IC and communicated to all of the measurement channels. In another aspect, the multiple channel, GaN based illumination driver IC includes a power regulation module that supplies regulated voltage to various elements of each measurement channel only when any pulse trigger signal is in a state that triggers the firing of an illumination pulse.

Abstract: A single-ended receiver is coupled to an input-output (I/O) pin of a command and address (CA) bus. The receiver is configurable with dual-mode I/O support to operate the CA bus in a low-swing mode and a high-swing mode. The receiver is configurable to receive a first command on the I/O pin while in the high-swing mode, initiate calibration of the slave device to operate in the low-swing mode in response to the first command, switch the slave device to operate in the low-swing mode while the CA bus remains active, and to receive a second command on the I/O pin while in the low-swing mode.

Abstract: The present disclosure relates generally to systems and methods for configuring architectures for a sensor, and more particularly for light detection and ranging (hereinafter, “LIDAR”) systems based on ASIC sensor architectures supporting autonomous navigation systems. Effective ASIC sensor architecture can enable an improved correlation between sensor data as well as configurability and responsiveness of the system to its surrounding environment and avoid any unnecessary delay within the decision-making process that may result in a failure of the autonomous driving system. It may be essential to integrated multiple functions within an electronic module and implement the functionality with one or more ASICs.

Abstract: A pharmaceutical composition containing cinacalcet or pharmaceutically acceptable salts thereof and one or more pharmaceutically acceptable excipients. A pharmaceutical composition containing cinacalcet or pharmaceutically acceptable salts thereof having a particle size distribution D90 equal to or less than 20 ?m, D50 equal to or less than 10 ?m, and D10 equal to or less than 5 ?m and one or more and binders in an amount of 0.9% w/w or less, relative to the total weight of composition, where the composition is not free of binder and that the total amount of binder does not exceed 0.9% w/w relative to the total weight of the composition.

Abstract: A first threshold corresponds to a data change at which a backup is triggered. A second threshold corresponds to a time interval at which the backup is triggered. A client is polled to obtain a first value indicating an amount of data changed since a last backup. A second value is tracked indicating an amount of time elapsed since the last backup. A determination is made as to whether to trigger the backup based on at least one of the first value exceeding the first threshold or the second value exceeding the second threshold. When the backup is not triggered because neither the first value exceeds the first threshold nor the second value exceeds the second threshold, the backup is triggered regardless based on a degree to which the first threshold has been reached, a degree to which the second threshold has been reached, and current usage of resources.

Abstract: The invention relates to vortioxetine hydrobromide having particle size distribution of D98 100-200?, D50 35-90? and D5 7-30? as well as to a stable, reproducible and bioequivalent pharmaceutical composition comprising vortioxetine hydrobromide having particle size distribution of D98 100-200?, D50 35-90? and D5 7-30? and one or more pharmaceutically acceptable excipient. It is produced by wet granulation techniques.

Abstract: Images of an eye are captured at respective time instances by a camera of a head-mounted device. For each time instance, a position of a center of corneal curvature is estimated using an image captured at that time instance, a position of a pupil center is estimated using an image captured at that time instance, and a line is determined through the estimated corneal curvature center position and the estimated pupil center position. A first estimated position of a center of the eye is computed based on the lines determined for time instances in a first time period. A second estimated position of the center of the eye is computed based on the lines determined for time instances in a second time period. Relocation of the head-mounted device relative to a user's head is detected based on the first and second estimated positions of the eye center.

Abstract: Images of an eye are captured by a camera. For each of the images, gaze data is obtained and a position of a pupil center is estimated in the image. The gaze data indicates a gaze point and/or gaze direction of the eye when the image was captured. A mapping is calibrated using the obtained gaze data and the estimated positions of the pupil center. The mapping maps positions of the pupil center in images captured by the camera to gaze points at a surface, or to gaze directions. A further image of the eye is captured by the camera. A position of the pupil center is estimated in the further image. Gaze tracking is performed using the calibrated mapping and the estimated position of the pupil center in the further image. These steps may for example be performed at a HMD.

Abstract: A remote agent for performing a backup of a virtual machine includes a persistent storage that stores backup policies and a backup manager that obtains a backup generation request for the virtual machine and, in response to the backup generation request, performs a component validation analysis of a production host that hosts the virtual machine to identify a backup state of the production host; makes a first determination, based on the backup state of the production host, that the production host is in a backup-enabled state; and, in response to the first determination, generates a backup of the virtual machine, using the backup policies, for storage in a backup storage; and validates that the backup of the virtual machine is stored in the backup storage based on a reduced size representation of the backup and a reduced size representation of a copy of the backup in the backup storage.

Abstract: Methods and systems for performing three dimensional LIDAR measurements with an integrated LIDAR measurement device are described herein. In one aspect, a return signal receiver generates a pulse trigger signal that triggers the generation of a pulse of illumination light and data acquisition of a return signal, and also triggers the time of flight calculation by time to digital conversion. In addition, the return signal receiver also estimates the width and peak amplitude of each return pulse, and samples each return pulse waveform individually over a sampling window that includes the peak amplitude of each return pulse waveform. In a further aspect, the time of flight associated with each return pulse is estimated based on a coarse timing estimate and a fine timing estimate. In another aspect, the time of flight is measured from the measured pulse due to internal optical crosstalk and a valid return pulse.

Abstract: The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library.

Abstract: Described herein are systems and methods that can adjust the performance of a transimpedance amplifier (TIA) in order to compensate for changing environmental and/or manufacturing conditions. In some embodiments, the changing environmental and/or manufacturing conditions may cause a reduction in beta of a bipolar junction transistor (BJT) in the TIA. A low beta may result in a high base current for the BJT causing the output voltage of the TIA to be formatted as an unusable signal output. To compensate for the low beta, the TIA generates an intermediate signal voltage, based on the base current and beta that is compared with the PN junction bias voltage on another BJT. Based on the comparison, the state of a digital state machine may be incremented, and a threshold base current is determined. This threshold base current may decide whether to compensate the operation of the TIA, or discard the chip.

Abstract: Described herein are systems and methods that create a capacitive link based on a rotating cylinder capacitor. A cylindrical rotor rotates around a shaft and maintains an air gap between the cylindrical rotor and the shaft and to create one or more air gap capacitors. A first subsystem, comprising a light detection and ranging components, is coupled to the rotor. A second sub-subsystem, comprising data analysis functions, is coupled to the shaft. The first subsystem and the second subsystem are coupled via capacitive links created by the air gap capacitors. The communication signaling utilized on the capacitive links may be bi-directional and differential signaling. The first subsystem and the second subsystem may comprise a LIDAR light detection and ranging system. The second subsystem may power the first subsystem via inductive coupling.

Abstract: Disclosed is a method for detecting a shadow in an image of an eye region of a user wearing a Head Mounted Device, HMD. The method comprises obtaining, from a camera of the HMD, an image of the eye region of the user wearing a HMD and determining an area of interest in the image, the area of interest comprising a plurality of subareas. The method further comprises determining a first brightness level for a first subarea of the plurality of subareas and determining a second brightness level for a second subarea of the plurality of subareas. The method further comprises comparing the first brightness level with the second brightness level, and, based on the comparing, selectively generating a signal indicating a shadow.

Abstract: A remote agent for performing a backup of a virtual machine includes a persistent storage that stores backup policies and a backup manager that obtains a backup generation request for the virtual machine and, in response to the backup generation request, performs a component validation analysis of a production host that hosts the virtual machine to identify a backup state of the production host; makes a first determination, based on the backup state of the production host, that the production host is in a backup-enabled state; and, in response to the first determination, generates a backup of the virtual machine, using the backup policies, for storage in a backup storage; and validates that the backup of the virtual machine is stored in the backup storage based on a reduced size representation of the backup and a reduced size representation of a copy of the backup in the backup storage.

Abstract: A receiver includes a decision circuit, a circuit to adjust an input signal of the decision circuit, a correction circuit and a control circuit. The decision circuit makes a data decision based on an input signal of the decision circuit. The circuit to adjust the input signal of the decision circuit adjusts the input signal of the decision circuit based on an input correction signal. The correction circuit combines a plurality of signals corresponding to different input correction parameters into a preliminary input correction signal. An input of the correction circuit is coupled to an output of the decision circuit. The control circuit maps the preliminary input correction signal into the input correction signal using a nonlinear code mapping.

Abstract: LIDAR measurement systems employing a multiple channel, GaN based illumination driver integrated circuit (IC) are described herein. In one aspect, the multiple channel, GaN based illumination driver IC selectively couples each illumination source associated with each measurement channel to a source of electrical power to generate a measurement pulse of illumination light. In one aspect, each pulse trigger signal associated with each measurement channel is received on a separate node of the IC. In another aspect, additional control signals are received on separate nodes of the IC and communicated to all of the measurement channels. In another aspect, the multiple channel, GaN based illumination driver IC includes a power regulation module that supplies regulated voltage to various elements of each measurement channel only when any pulse trigger signal is in a state that triggers the firing of an illumination pulse.

Abstract: Described herein are systems and methods that detect an electromagnetic signal in a constant interference environment. In one embodiment, the electromagnetic signal is a light signal. A constant interference detector may detect false signal “hits” generated by constant interference, such as bright light saturation, from valid signals. The constant interference detector determines if there is constant interference for a time period that is greater than a time period of the valid signal. In one embodiment, if a received signal exceeds a programmable threshold value for a programmable period of time, when compared to previously stored ambient light, a control signal is generated to inform the next higher network layer of a sudden change in ambient light. This control signal can be used to either discard the present return or process the signal in a different way. A constant interference detector may be a component of a LIDAR system.

Abstract: A first threshold corresponds to a data change at which a backup is triggered. A second threshold corresponds to a time interval at which the backup is triggered. A client is polled to obtain a first value indicating an amount of data changed since a last backup. A second value is tracked indicating an amount of time elapsed since the last backup. A determination is made as to whether to trigger the backup based on at least one of the first value exceeding the first threshold or the second value exceeding the second threshold. When the backup is not triggered because neither the first value exceeds the first threshold nor the second value exceeds the second threshold, the backup is triggered regardless based on a degree to which the first threshold has been reached, a degree to which the second threshold has been reached, and current usage of resources.

Abstract: Methods and systems for performing three dimensional LIDAR measurements with an integrated LIDAR measurement device are described herein. In one aspect, a return signal receiver generates a pulse trigger signal that triggers the generation of a pulse of illumination light and data acquisition of a return signal, and also triggers the time of flight calculation by time to digital conversion. In addition, the return signal receiver also estimates the width and peak amplitude of each return pulse, and samples each return pulse waveform individually over a sampling window that includes the peak amplitude of each return pulse waveform. In a further aspect, the time of flight associated with each return pulse is estimated based on a coarse timing estimate and a fine timing estimate. In another aspect, the time of flight is measured from the measured pulse due to internal optical crosstalk and a valid return pulse.