Abstract: The invention relates to the use of an Engrailed protein as a medicament for increasing dopamine synthesis by dopaminergic neurons, in particular in the management of conditions associated with a decrease of dopamine levels without loss of dopaminergic neurons.

Abstract: The invention relates to the use of a reverse-transcriptase inhibitor in the prevention or treatment of a degenerative disease.

Abstract: Publisher-side content based filtering methods and systems are provided to select which subscribers shall receive each data-message sent by a publisher using an Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol. Methods and systems are provided for writer-side content based filtering and data distribution from a publisher to a plurality of subscribers using an Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol. Methods and systems are provided for performing scalable content-based filtering and distribution from a publisher to a plurality of subscribers using to the Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol.

Abstract: Publisher-side content based filtering methods and systems are provided to select which subscribers shall receive each data-message sent by a publisher using an Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol. Methods and systems are provided for writer-side content based filtering and data distribution from a publisher to a plurality of subscribers using an Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol. Methods and systems are provided for performing scalable content-based filtering and distribution from a publisher to a plurality of subscribers using the Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol.

Abstract: Publisher-side content based filtering methods and systems are provided to select which subscribers shall receive each data-message sent by a publisher using an Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol. Methods and systems are provided for writer-side content based filtering and data distribution from a publisher to a plurality of subscribers using an Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol. Methods and systems are provided for performing scalable content-based filtering and distribution from a publisher to a plurality of subscribers using the Object Management Group (OMG) Real-Time Publish-Subscribe (RTPS) protocol.

Abstract: The invention relates to the use of an Engrailed protein as a medicament for increasing dopamine synthesis by dopaminergic neurons, in particular in the management of conditions associated with a decrease of dopamine levels without loss of dopaminergic neurons

Abstract: A method of providing transports for a data distribution middleware over a plurality of transport networks is provided. A data distribution middleware with a pluggable transport layer is provided. A plurality of transport plugins in the transport layer are provided. Aliases are assigned to each of the transport plugins of the plurality of transport plugins, wherein at least one of the transport plugins of the plurality of transport plugins has a plurality of aliases.

Abstract: Techniques for execution of multiple threads in a multithreaded computing programming environment are disclosed. The techniques are especially well suited for environments that use multilayered programming architecture where a higher layer can build on the functions provided by a lower layer where the delay time is an important consideration. In one aspect, the conceptual notion of a “Worker” effectively serves to represent the thread-specific execution context for a thread of execution (“thread”) in a multithreaded computing environment. Another aspect, provides the notion of an Exclusion Area (EA) as logical lock that serves to protect shared resources in a multithreaded environment. The combination of the worker and EA are used to provide a powerful framework that, among other things, allows minimizing of the delay time.

Abstract: Aspects of the advancement provide for information to be synchronized in an asynchronous manner among two or more computing devices.

Abstract: Aspects of the invention provide for information to be synchronized in an asynchronous manner among two or more computing devices.

Abstract: Techniques for execution of multiple threads in a multithreaded computing programming environment are disclosed. The techniques are especially well suited for environments that use multilayered programming architecture where a higher layer can build on the functions provided by a lower layer where the delay time is an important consideration. In one aspect, the conceptual notion of a “Worker” effectively serves to represent the thread-specific execution context for a thread of execution (“thread”) in a multithreaded computing environment. Another aspect, provides the notion of an Exclusion Area (EA) as logical lock that serves to protect shared resources in a multithreaded environment. The combination of the worker and EA are used to provide a powerful framework that, among other things, allows minimizing of the delay time.

Abstract: Aspects of the invention provide for information to be synchronized in an asynchronous manner among two or more computing devices.

Abstract: A method of operating real-time middleware associated with at least one node of a data distribution system is provided. At least one pool of a plurality of fixed block size units of memory of the node is allocated (e.g., via an operating system call). Based on loan requests for dynamic memory elements on behalf of a user application executing on the node, an indication of at least one of the allocated fixed block size units to be lent is provided. A list of which allocated fixed block size units are being lent from the pool is maintained, including maintaining the list based on return requests, on behalf of the user application executing on the node, of fixed block size units of the pool. Substantially all of the dynamic memory elements of the real-time middleware associated with the node are provided from the at least one pool of allocated fixed block size units based on the loan requests on behalf of the user application.

Abstract: Aspects of the invention provide for information to be synchronized in an asynchronous manner among two or more computing devices.

Abstract: Aspects of the advancement provide for information to be synchronized in an asynchronous manner among two or more computing devices.

Abstract: A bridge to integrate representation of global data space in Data Distribution Service (DDS) and Data Management Systems (DBMS). The DDS concept of a keyed topic and a type is mapped to the DBMS notion of a keyed table and schema representing data-object instances. Rules are specified for translating between a DBMS table record and the DDS wire format representation. Four bridge components are possible: Bridge-DDS-DBMS-Publication to store outgoing published data; Bridge-DDSDBMS-Subscription to store incoming subscribed data; Bridge-DBMS-DDS-Publication to publish changes to a DBMS table; and Bridge-DBMS-DDS-Subscription to update a DBMS Table based on received data subscriptions from the network. Mechanisms are provided for preventing publication of data seen by DDS, and for preventing application of changes already made in a DBMS table.

Abstract: A channel 16 of a FinFET 10 has a channel core 24 and a channel envelope 32, each made from a semiconductor material defining a different lattice structure to exploit strained silicon properties. A gate is coupled to the channel envelope through a gate dielectric. Exemplary materials are Si and SiXGe1?x, wherein 78<x<92. The channel core 24 has a top surface 26 of width wc and an upstanding surface 28, 30 of height hc, preferably oriented 90° to one another. The channel envelope 32 is in contact with the top 26 and upstanding surfaces 28, 30 so that the area of interface is increased as compared to contact only along the top surface 26, improving electrical conductivity and gate 18 control over the channel 16. The height hc, can be tailored to enable a smaller scale FET 10 within a stabilized SRAM. Various methods of making the channel 16 are disclosed, including a mask and etch method, a handle wafer/carrier wafer method, and a shallow trench method.

Abstract: A method of fabricating a semiconductor device includes etching a substrate formed on a backside of a semiconductor wafer to form a recess in the substrate, and forming a sputter film in the recess, the sputter film including a first material having a coefficient of thermal expansion (CTE) which is at least substantially equal to a CTE of the substrate, and a second material having a thermal conductivity which is greater than a thermal conductivity of the substrate.

Abstract: A channel 16 of a FinFET 10 has a channel core 24 and a channel envelope 32, each made from a semiconductor material defining a different lattice structure to exploit strained silicon properties. A gate is coupled to the channel envelope through a gate dielectric. Exemplary materials are Si and SixGe1-x, wherein 78<x<92. The channel core 24 has a top surface 26 of width wc and an upstanding surface 28, 30 of height hc, preferably oriented 90° to one another. The channel envelope 32 is in contact with the top 26 and upstanding surfaces 28, 30 so that the area of interface is increased as compared to contact only along the top surface 26, improving electrical conductivity and gate 18 control over the channel 16. The height hc can be tailored to enable a smaller scale FET 10 within a stabilized SRAM. Various methods of making the channel 16 are disclosed, including a mask and etch method, a handle wafer/carrier wafer method, and a shallow trench method.

Abstract: A ring oscillator row circuit for evaluating memory cell performance provides for circuit delay and performance measurements in an actual memory circuit environment. A ring oscillator is implemented with a row of memory cells and has outputs connected to one or more bitlines along with other memory cells that are substantially identical to the ring oscillator cells. Logic may be included for providing a fully functional memory array, so that the cells other than the ring oscillator cells can be used for storage when the ring oscillator row wordlines are disabled. One or both power supply rails of individual cross-coupled inverter stages forming static memory cells used in the ring oscillator circuit may be isolated from each other in order to introduce a voltage asymmetry so that circuit asymmetry effects on delay can be evaluated.