Patents by Inventor Richard A. Young

Richard A. Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cutting tool and method of operating same
    Patent number: 9186804
    Abstract: A cutting tool and method of operating cutting tool. The tool includes a support having a first side and a second side. The tool further includes a handle coupled to at least one of the first side and the second side. The handle includes a blade, wherein the handle is configured to move the blade between a first position and a second position. An alignment guide is coupled to the support. The alignment guide includes a channel configured to receive the blade positioned in the second position.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: November 17, 2015
    Assignee: The Boeing Company
    Inventors: David Scott Wright, Christine Mary Anderson, Curt Backman, Donald Wayne Coffland, Aaron Robert Ayers, Donald Richard Young
  • Super-enhancers and methods of use thereof
    Patent number: 9181580
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: November 10, 2015
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Richard A. Young, Warren Whyte, Denes Hnisz, Jakob Loven, Heather Hoke, David Orlando, Charles Y. Lin, Tony Lee
  • Insertable Filter Unit
    Publication number: 20150313278
    Abstract: An insertable filter unit for insertion into a smoking article filter having a recess, wherein the insertable filter unit comprises an outer casing defining a cavity for storing a smoke modifying agent, and wherein the insertable filter unit is arranged to be inserted into the recess of the smoking article filter by a user.
    Type: Application
    Filed: December 19, 2013
    Publication date: November 5, 2015
    Applicant: British American Tobacco (Investments) Limited
    Inventors: Aaron BROOKBANK, Richard YOUNG
  • RHO KINASE INHIBITORS
    Publication number: 20150297581
    Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.
    Type: Application
    Filed: June 30, 2015
    Publication date: October 22, 2015
    Inventors: Todd Bosanac, John David Ginn, Eugene Richard Hickey, Thomas Martin Kirrane, Jr., Weimin Liu, Anthony S. Prokopowicz, Sabine K. Schlyer, Cheng-Kon Shih, Roger John Snow, Michael Robert Turner, Frank Wu, Erick Richard Young
  • PYRROL-1-YL BENZOIC ACID DERIVATIVES USEFUL AS MYC INHIBITORS
    Publication number: 20150291521
    Abstract: The present invention provides compounds of Formula (I-A), (I-B), and (I-C), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting Myc (e.g., c-Myc) activity. The present invention further provides methods of using the compounds described herein for treating Myc-mediated disorders (e.g., cancer and other proliferative diseases). The present invention also provides assays for identifying Myc inhibitors.
    Type: Application
    Filed: November 1, 2013
    Publication date: October 15, 2015
    Inventors: James E. Bradner, Michael R. McKeown, Peter B. Rahl, Richard A. Young, Jason J. Marineau
  • Combination methods for treatment of disease
    Patent number: 9155724
    Abstract: In some aspects, the invention provides compositions and methods of use for treating a variety of diseases. In some aspect, the compositions and methods involve combined modulation of transcriptional modulators.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: October 13, 2015
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Peter B. Rahl, Richard A. Young
  • WNT pathway stimulation in reprogramming somatic cells with nuclear reprogramming factors
    Patent number: 9102919
    Abstract: The invention provides compositions and methods of use in reprogramming somatic cells. Compositions and methods of the invention are of use, e.g., for generating or modulating (e.g., enhancing) generation of induced pluripotent stem cells by reprogramming somatic cells. The reprogrammed somatic cells are useful for a number of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a pluripotent state and/or enhances the speed and/or efficiency of reprogramming. Certain of the compositions and methods relate to modulating the Wnt pathway.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: August 11, 2015
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Brett Chevalier, Alexander Marson, Richard A. Young, Ruth Foreman, Rudolf Jaenisch
  • SLEEVE
    Publication number: 20150189914
    Abstract: A sleeve (1) for holding a plurality of elongate elements (9) positioned in end-to-end relationship is disclosed. The sleeve has an elongate body (2) with opposite ends (10,11) and a space (3) defined therebetween to receive the elongate elements (9). The elongate body has an opening (4) between the ends (10,11) that is configured to enable a user to contact elongate elements (9) received in the sleeve (1) through the opening (4) and push them along, and out of one end of the sleeve (1).
    Type: Application
    Filed: May 24, 2013
    Publication date: July 9, 2015
    Applicant: British American Tobacco (Investments) Limited
    Inventors: Michael Simpson, Richard Young, John Richardson
  • Genome-wide Method of Assessing Interactions Between Chemical Entities And Their Target Molecules
    Publication number: 20150167062
    Abstract: The invention is directed to a method of mapping, across a genome, interaction of a drug with one or more factors that associate with the genome.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 18, 2015
    Inventors: Richard A. Young, James E. Bradner, Peter B. Rahl, Lars Anders, Jason J. Marineau, Jun Qi, Matthew G. Guenther
  • SUPER-ENHANCERS AND METHODS OF USE THEREOF
    Publication number: 20150111761
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Application
    Filed: October 24, 2014
    Publication date: April 23, 2015
    Inventors: Richard A. Young, Warren Whyte, Denes Hnisz, Jakob Loven, Heather Hoke, David Orlando, Charles Y. Lin, Tony Lee
  • Wireless devices including printed integrated circuitry and methods for manufacturing and using the same
    Patent number: 9004366
    Abstract: Printed integrated circuitry and attached antenna and/or inductor for sensors, electronic article surveillance (EAS), radio frequency (RF) and/or RF identification (RFID) tags and devices, and methods for its manufacture. The tag generally includes printed integrated circuitry on one carrier and an antenna and/or inductor on another carrier, the integrated circuitry being electrically coupled to the antenna and/or inductor. The method of manufacture generally includes of printing an integrated circuit having a plurality of first pads on a carrier, forming an antenna and/or inductor having a plurality of second pads on a substrate, and attaching at least two of the first pads of the printed integrated circuit to corresponding second pads of the antenna and/or inductor.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: April 14, 2015
    Assignee: Thin Film Electronics ASA
    Inventors: Patrick Smith, Criswell Choi, Vikram Pavate, James Montague Cleeves, Vivek Subramanian, Richard Young, Vince Biviano
  • Devices and methods for shielding displays from electrostatic discharge
    Patent number: 9001280
    Abstract: Methods and devices for shielding displays from electrostatic discharge (ESD) are provided. In one example, a display of an electronic device may include a high resistivity shielding layer configured to protect electrical components from static charges. The display may also include a conductive layer electrically coupled to the high resistivity shielding layer and configured to decrease a discharge time of static charges from the high resistivity shielding layer. The display may include a grounding layer and a conductor electrically coupled between the conductive layer and the grounding layer to direct static charges from the conductive layer to the grounding layer.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: April 7, 2015
    Assignee: Apple Inc.
    Inventors: Ming Xu, Zhibing Ge, Cheng-Ho Yu, Cheng Chen, Abbas Jamshidi-Roudbari, Lynn Richard Youngs
  • Pack for Smoking Articles
    Publication number: 20140374291
    Abstract: The invention relates to a pack (1) for smoking articles. The pack (1) comprises a plurality of panels (4, 5, 6, 7) and a plurality of pack edges (16, 17, 18, 19) where the panels meet. At least one of the pack edges comprises a plurality of incisions (22) extending entirely through the material of the pack and configured such that the edge is uneven along at least part of its length.
    Type: Application
    Filed: December 31, 2012
    Publication date: December 25, 2014
    Inventor: Richard Young
  • Drill motor enhancement providing improved sealing performance and longevity
    Patent number: 8915312
    Abstract: Enhancements to a drill motor include a bearing pack assembly, a balancing piston, a recording transducer package (RTP), and a latch rod assembly for a drill motor to improve performance and reliability of a drill motor. The bearing pack assembly includes a bearing housing coupled to an end cap and a drive shaft extending into the end cap and the bearing housing. The bearing pack assembly also includes a thrust bearing disposed within the bearing housing, wherein the thrust bearing separates the drive shaft and the bearing housing, and a bearing sleeve disposed within the bearing housing, wherein a radial bearing is placed between the bearing sleeve and the drive shaft. The balancing piston includes a first and second hydrodynamic seal. The recording transducer package is self powered and gathers data from a plurality of sensors in the downhole tool.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: December 23, 2014
    Assignee: Multishot LLC
    Inventors: Gilbert Villarreal, Allen Richard Young
  • METHODS OF DOWNREGULATING TRANSLOCATED ONCOGENE EXPRESSION USING BROMODOMAIN INHIBITORS
    Publication number: 20140371157
    Abstract: Disclosed herein are novel methods and compositions useful for inhibiting interaction between a bromodomain protein and an immunoglobulin (Ig) regulatory element. The methods and compositions are particularly useful for downregulating expression of an oncogene translocated with an Ig locus, as well as for treating a cancer (e.g., hematological malignancy) characterized by increased expression of an oncogene which is translocated with an Ig locus.
    Type: Application
    Filed: August 30, 2012
    Publication date: December 18, 2014
    Applicants: DANA-FARBER CANCER INSTITUTE, INC., WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Richard A. Young, Peter B. Rahl, James Bradner
  • Markers for and methods of targeting tumor stem cells
    Patent number: 8912156
    Abstract: The invention provides methods of targeting tumor stem cells that comprise inhibiting the level and/or activity of HDAC1, HDAC7 and phosphorylated HDAC7. The invention further provides methods for identifying tumor stem cells comprising detecting increased levels and/or activity of HDAC1, HDAC7 and phosphorylated HDAC7. Further provided are kits and articles of manufacture comprising inhibitors of the level and/or activity of HDAC1, HDAC7 and phosphorylated HDAC7. Methods for screening for inhibitors of the level and/or activity of HDAC1, HDAC7 and phosphorylated HDAC7 are also provided.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: December 16, 2014
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Tan A. Ince, Tong Ihn Lee, Richard A. Young
  • RHO KINASE INHIBITORS
    Publication number: 20140357652
    Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventors: Todd Bosanac, John David Ginn, Eugene Richard Hickey, Thomas Martin Kirrane, JR., Weimin Liu, Anthony S. Prokopowicz, Sabine K. Schlyer, Cheng-Kon Shih, Roger John Snow, Michael Robert Turner, Frank Wu, Erick Richard Young
  • Impact Protection Structures for Vehicles and Vehicles Incorporating the Same
    Publication number: 20140346813
    Abstract: Impact protection structures for vehicles are described. An impact protection structure includes a support structure of the vehicle, an interior rail coupled to the support structure, and an exterior rail coupled to the interior rail. The exterior rail has an inboard boundary wall positioned between an upper mounting region and a lower mounting region. The upper and the lower exterior mounting region of the exterior rail are coupled to an upper and a lower mounting region of the interior rail. At least a portion of the inboard boundary wall is spaced apart from an outboard wall of the interior rail such that when the exterior rail is impacted by a blunt-object barrier, the inboard boundary wall of the exterior rail deforms, thereby damping energy of the impact at the exterior rail and arresting crack propagation between the exterior rail and the interior rail.
    Type: Application
    Filed: August 13, 2014
    Publication date: November 27, 2014
    Inventors: Jonathan Richard Young, Donald James Robert Parr, Ernest Matthew Villanueva, Nathan Nelson, Paul Dewitt Frey
  • SMOKING ARTICLE FILTER AND INSERTABLE FILTER UNIT THEREFOR
    Publication number: 20140332014
    Abstract: A smoking article filter (20) comprises a recess (25) to receive a filter insert unit (30). The filter insert unit (30) is secured to the filter (20) once inserted. The filter (20) and the filter insert unit (30) may comprise additives such as flavourants, colourants or sorbents.
    Type: Application
    Filed: June 27, 2012
    Publication date: November 13, 2014
    Applicant: BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED
    Inventors: Graham Penrose, Michael Malthouse, David Wake, Gary Fulcher, Michael Simpson, Aaron Brookbank, Gordon Grierson, Jon Hindley, John Sampson, Rabya Khan-Dar, Karl Kaljura, Nelson Ong, John Richardson, John Major, Richard Young
  • Package for smoking articles with lid flap
    Patent number: 8875878
    Abstract: The present invention relates to a package for smoking articles comprising a container portion (2) and a lid (3). The lid is hingedly connected to the container 5 portion (2) to enclose a space defined by the container portion (2) when the lid (3) is closed. The lid (3) includes an end portion (16) and a wall (12) extending from the end portion (16) that overlaps a wall (6) of the container portion (2) when closed. A flap (26,93,107,120) extends from a face of one of said walls having a free end (29,96,109,125), and a cut-out (51,80,102) is formed in the other of said walls, 10 wherein one of the cut-out (51,80) or the free end (109,125) of the flap (107,120) has a first edge (54,65,73,87,115,127) and a second edge (55,56,66,74,88,90,116,128).
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: November 4, 2014
    Assignee: British American Tobacco (Investments) Limited
    Inventor: Richard Young