Patents by Inventor Robert G. Matheny

Robert G. Matheny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Extracellular matrix constructs for treating damaged biological tissue
    Patent number: 9642692
    Abstract: Extracellular matrix (ECM) constructs having a biodegradable support scaffold and an anchoring mechanism, which includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein. In a preferred embodiment, the support scaffold and anchoring mechanism comprise an ECM material. In some embodiments, the microneedles are also capable of administering a biologically active agent and/or a pharmacological composition to the engaged tissue.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: May 9, 2017
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Extracellular matrix encasement structures and methods
    Patent number: 9636437
    Abstract: A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: May 2, 2017
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100522
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G. Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100514
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100517
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G. Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100523
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G. Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100516
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G. Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100518
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100513
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100512
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G. Matheny
  • Cardiovascular Prostheses
    Publication number: 20170100515
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from acellular extracellular matrix (ECM). The cardiovascular prostheses comprise various compositions, such as ECM based compositions, and structures, such as particulate structures, mesh constructs, encasement structures, coated structures and multi-sheet laminate structures.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventor: Robert G. Matheny
  • Extracellular matrix constructs for treating damaged biological tissue
    Patent number: 9610149
    Abstract: Extracellular matrix (ECM) constructs having a biodegradable support scaffold and an anchoring mechanism, which includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein. In a preferred embodiment, the support scaffold and anchoring mechanism comprise an ECM material. In some embodiments, the microneedles are also capable of administering a biologically active agent and/or a pharmacological composition to the engaged tissue.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: April 4, 2017
    Assignee: CORMATRIC CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Reinforced vascular prostheses
    Patent number: 9533072
    Abstract: Vascular grafts for treating, reconstructing and replacing damaged or diseased cardiovascular vessels that are formed from decellularized extracellular matrix (ECM). The vascular grafts include outer or outer and inner coatings that provide structural reinforcement.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: January 3, 2017
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Reinforced vascular protheses
    Patent number: 9498559
    Abstract: Vascular grafts for treating, reconstructing and replacing damaged or diseased cardiovascular vessels that are formed from decellularized extracellular matrix (ECM). The vascular grafts include outer or outer and inner coatings that provide structural reinforcement.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: November 22, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Prosthetic Tissue Valves
    Publication number: 20160317300
    Abstract: A prosthetic valve comprising a conical shaped sheet member comprising an extracellular matrix (ECM) composition and an internal multi-link support stent structure, the sheet member having a plurality of open slit regions that are disposed uniformly on linear planes that are parallel to the sheet member longitudinal axis, and a proximal annulus engagement end diameter and length ratio in the range of 5:1 to 2:1.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Robert G Matheny, Minh X Vo, Carlos C Chang, Selvamuthu k Natarajan
  • Prosthetic Tissue Valves
    Publication number: 20160317292
    Abstract: A prosthetic valve comprising a conical shaped sheet member comprising an extracellular matrix (ECM) composition, the sheet member having a plurality of open slit regions that are disposed uniformly on linear planes that are parallel to the sheet member longitudinal axis, and a proximal annulus engagement end diameter and length ratio in the range of 5:1 to 2:1.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Robert G. Matheny, Minh X. Vo, Carlos C. Chang, Selvamuthu K. Natarajan
  • Prosthetic Tissue Valves
    Publication number: 20160317293
    Abstract: A prosthetic valve comprising a conical shaped sheet member comprising an extracellular matrix (ECM) composition, the sheet member having a plurality of ribbons projecting the sheet member proximal end, the distal ends of the ribbons being positioned proximate each other, wherein the sheet member comprises a conical shape.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Robert G. Matheny, Minh X. Vo, Carlos C. Chang, Selvamuthu K. Natarajan
  • Prosthetic Tissue Valves
    Publication number: 20160317294
    Abstract: A prosthetic valve comprising a conical shaped sheet member comprising an extracellular matrix (ECM) composition, the sheet member having a plurality of open slit regions that are disposed uniformly on linear planes that are parallel to the sheet member longitudinal axis, a proximal annulus engagement end diameter and length ratio in the range of 5:1 to 2:1 and at least one valve leaflet.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Robert G. Matheny, Minh X. Vo, Carlos C. Chang, Selvamuthu K. Natarajan
  • Prosthetic Tissue Valves
    Publication number: 20160317296
    Abstract: A prosthetic valve comprising a plurality of ribbons comprising an extracellular matrix (ECM) composition, the proximal ends of the plurality of ribbons being positioned circumferentially and proximate each other, the distal ends of the plurality of ribbons also being positioned proximate each other, wherein a conical shaped valve member is formed.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Robert G Matheny, Minh X Vo, Carlos C Chang, Selvamuthu k Natarajan
  • Sterilized and decellularized extracellular matrix for treating cardiac arrhythmia
    Patent number: 9446078
    Abstract: Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: September 20, 2016
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny