Patents by Inventor Robert G. Matheny

Robert G. Matheny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artificial skeletal material and constructs formed therefrom
    Patent number: 9381218
    Abstract: A bioresorbable skeletal construct member formed from an osteoinductive composition comprising autogenic bone and an extracellular matrix (ECM) material, the construct member being configured to induce osteoanagenesis and angiogenesis when implanted proximate endogenous bone and tissue.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: July 5, 2016
    Assignee: CerMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Biocompatable Annular Prostheses and Methods for Forming Same
    Publication number: 20160166730
    Abstract: Annular prostheses comprising an elongated tubular member formed from an extracellular matrix (ECM) composition comprising ECM from a mammalian tissue source, which, when disposed proximate damaged cardiovascular tissue, induces modulated healing, including modulation of inflammation and bioremodeling. The ECM can also be augmented with a supplemental biologically active agent, such as a growth factor, to enhance modulation of inflammation and bioremodeling.
    Type: Application
    Filed: November 30, 2015
    Publication date: June 16, 2016
    Inventor: Robert G. Matheny
  • Vascular casted prostheses and methods of forming same for treating biological tissue
    Publication number: 20160157984
    Abstract: Bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition.
    Type: Application
    Filed: March 23, 2015
    Publication date: June 9, 2016
    Inventors: Robert G. Matheny, Craig N Ferrante
  • Vascular casted prostheses and methods of forming same for treating biological tissue
    Publication number: 20160157982
    Abstract: Bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition.
    Type: Application
    Filed: March 23, 2015
    Publication date: June 9, 2016
    Inventors: Robert G. Matheny, Craig N. Ferrante
  • Vascular casted prostheses and methods of forming same for treating biological tissue
    Publication number: 20160157983
    Abstract: Methods of treating biological tissue with bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition.
    Type: Application
    Filed: March 23, 2015
    Publication date: June 9, 2016
    Inventors: Robert G. Matheny, Craig N. Ferrante
  • Anisotropic Constructs and Methods for Forming and Using Same for Treating Damaged Biological Tissue
    Publication number: 20160158414
    Abstract: Anisotropic constructs having a base member with a defined surface that includes a plurality of substantially parallel equidistant linear channels that are configured to modulate the polarity and proliferation of cells through spatial and biomechanical cues. The constructs are also capable of administering a biologically active agent and/or a pharmacological composition to tissue.
    Type: Application
    Filed: November 30, 2015
    Publication date: June 9, 2016
    Inventor: Robert G. Matheny
  • Tissue prostheses for repairing, reconstructing and replacing damaged or diseased biological structures and associated tissue
    Patent number: 9352070
    Abstract: Non-antigenic, resilient, bioremodelable, biocompatible tissue prostheses that can be engineered into a variety of shapes and used to repair, augment, reconstruct or replace damaged or diseased biological structures and associated tissue.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: May 31, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Mesh Fiber Members and Methods for Forming and Using Same for Treating Damaged Biological Tissue
    Publication number: 20160144076
    Abstract: A mesh fiber member having a plurality of biodegradable fibers, the mesh fiber member being configured to induce modulated healing of damaged biological tissue when deployed proximate thereto. The strands comprise an extracellular matrix (ECM) composition or an ECM-mimicking biomaterial composition, such as poly(glycerol sebacate) (PGS), and can include a biodegradable ECM, polymeric or ECM-mimicking biomaterial composition coating.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 26, 2016
    Inventors: Robert G. Matheny, Derek S. Francis
  • Biological Constructs for Treating Damaged Organs and Tissue
    Publication number: 20160144073
    Abstract: Biological constructs that can be engineered into a variety of shapes and employed to treat, augment and/or support damaged or diseased mammalian organs and/or tissue related thereto. The shapes include jackets and bands that are configured to encase a preselected region of a mammalian organ.
    Type: Application
    Filed: December 3, 2015
    Publication date: May 26, 2016
    Inventor: Robert G. Matheny
  • Biological Constructs for Treating Damaged Organs and Tissue
    Publication number: 20160143738
    Abstract: Biological constructs that can be engineered into a variety of shapes and employed to treat, augment and/or support damaged or diseased mammalian organs and/or tissue related thereto. The shapes include jackets and bands that are configured to encase a preselected region of a mammalian organ.
    Type: Application
    Filed: December 3, 2015
    Publication date: May 26, 2016
    Inventor: Robert G. Matheny
  • Regenerative Respiratory Tract Prostheses
    Publication number: 20160143729
    Abstract: A regenerative respiratory tract prosthesis comprising a tubular extracellular matrix (ECM) member having a lumen therethrough, at least first and second biodegradable polymeric anchors disposed on the tubular member exterior surface. The first and second anchors can include a microneedle tissue engagement member.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 26, 2016
    Inventor: Robert G. Matheny
  • Mesh Fiber Members and Methods for Forming and Using Same for Treating Damaged Biological Tissue
    Publication number: 20160144072
    Abstract: A mesh fiber member having a plurality of biodegradable fibers, the mesh fiber member being configured to induce modulated healing of damaged biological tissue when deployed proximate thereto. The strands comprise an extracellular matrix (ECM) composition or an ECM-mimicking biomaterial composition, such as poly(glycerol sebacate) (PGS), and can include a biodegradable ECM, polymeric or ECM-mimicking biomaterial composition coating.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 26, 2016
    Inventors: Robert G. Matheny, Derek S. Francis
  • Mesh Fiber Members and Methods for Forming and Using Same for Treating Damaged Biological Tissue
    Publication number: 20160143720
    Abstract: A mesh fiber member having a plurality of biodegradable fibers, the mesh fiber member being configured to induce modulated healing of damaged biological tissue when deployed proximate thereto. The strands comprise an extracellular matrix (ECM) composition or an ECM-mimicking biomaterial composition, such as poly(glycerol sebacate) (PGS), and can include a biodegradable ECM, polymeric or ECM-mimicking biomaterial composition coating.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 26, 2016
    Inventors: Robert G. Matheny, Derek S. Francis
  • Biological Constructs for Treating Damaged Organs and Tissue
    Publication number: 20160144074
    Abstract: Biological constructs that can be engineered into a variety of shapes and employed to treat, augment and/or support damaged or diseased mammalian organs and/or tissue related thereto. The shapes include jackets and bands that are configured to encase a preselected region of a mammalian organ.
    Type: Application
    Filed: December 3, 2015
    Publication date: May 26, 2016
    Inventor: Robert G Matheny
  • Extracellular matrix (ECM) structures for tissue regeneration
    Patent number: 9333277
    Abstract: An extracellular matrix (ECM) structure for tissue regeneration, the ECM structure having a a sheet member comprising small intestine submucosa (SIS), the SIS sheet member being folded and laminated proximate the sheet member edge, wherein a folded laminated ECM structure having a cavity therein is formed, the ECM structure further including an ECM composition that is disposed in the ECM structure cavity, the ECM composition including liver basement membrane, urinary bladder submucosa, a mesenchymal stem cell and a growth factor.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: May 10, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Method and system for treatment of cardiovascular disorders
    Patent number: 9327000
    Abstract: Methods for treating a cardiovascular disorder comprising administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue associated with the cardiovascular disorder, and provision of ventricular assistance.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: May 3, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Compositions for regenerating defective or absent myocardium
    Patent number: 9327055
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: May 3, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Compositions and methods for preventing cardiac arrhythmia
    Patent number: 9308225
    Abstract: Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: April 12, 2016
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Prosthetic tissue valves and methods for anchoring same to cardiovascular structures
    Patent number: 9308084
    Abstract: A prosthetic atrioventricular tissue valve comprising a continuous tubular member formed from a first biocompatible material, the tubular member having proximal and distal ends, and at least one valve leaflet formed therein, the distal end of the tubular member including cardiovascular structure engagement means for connecting the tubular member to a cardiovascular structure, the cardiovascular structure engagement means comprising a plurality of elongated members that extend distally from the distal end of the tubular member.
    Type: Grant
    Filed: March 29, 2014
    Date of Patent: April 12, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC
    Inventor: Robert G Matheny
  • Compositions for regenerating defective or absent myocardium
    Patent number: 9295758
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: March 29, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny