Patents by Inventor Robert G. Matheny

Robert G. Matheny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and System for Treatment of Damaged Biological Tissue
    Publication number: 20160082153
    Abstract: Biomaterial compositions and articles comprising mesothelial tissue and a glycosaminoglycan (GAG), for treating damaged biological tissue; particularly, damaged cardiovascular tissue. The biomaterial compositions and articles can also include additional biologically active agents, such as growth factors. The biomaterial compositions and articles induce modulated healing, including modulation of inflammation and induced neovascularization when administered to damaged biological tissue.
    Type: Application
    Filed: December 5, 2015
    Publication date: March 24, 2016
    Inventor: Robert G Matheny
  • Method and System for Treatment of Damaged Biological Tissue
    Publication number: 20160082154
    Abstract: Biomaterial compositions and articles comprising mesothelial tissue and a growth factor, for treating damaged biological tissue; particularly, damaged cardiovascular tissue. The biomaterial compositions and articles induce modulated healing, including modulation of inflammation and induced neovascularization, when administered to damaged biological tissue.
    Type: Application
    Filed: December 5, 2015
    Publication date: March 24, 2016
    Inventor: Robert G Matheny
  • Compositions for regenerating defective or absent myocardium
    Patent number: 9289532
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: March 22, 2016
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Extracellular matrix encasement structures and methods
    Patent number: 9283302
    Abstract: A remodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region and at least one lead conduit, the internal region being configured to receive a device therein, the lead conduit being configures to receive at least one device lead therein, the bioremodelable material comprising an extracellular matrix (ECM) composition that includes an ECM component derived from a mammalian source.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: March 15, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Method and system for treatment of cardiovascular disorders
    Patent number: 9265799
    Abstract: Methods for treating a cardiovascular disorder comprising administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue associated with the cardiovascular disorder, and provision of ventricular assistance.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: February 23, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Method and system for treatment of cardiovascular disorders
    Patent number: 9265798
    Abstract: Methods for treating a cardiovascular disorder comprising administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue associated with the cardiovascular disorder, and provision of ventricular assistance.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: February 23, 2016
    Assignee: CORMATRIX CARDIOVASCULAR, INC
    Inventor: Robert G Matheny
  • Compositions for Regenerating Defective or Absent Myocardium
    Publication number: 20160038644
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Application
    Filed: May 5, 2014
    Publication date: February 11, 2016
    Inventor: Robert G. Matheny
  • Prosthetic Vascular Conduits for Cardiovascular Structures
    Publication number: 20160022407
    Abstract: Vascular grafts for reconstructing and/or replacing damaged or diseased cardiovascular vessels that are formed from decellularized fetal small intestine.
    Type: Application
    Filed: July 22, 2014
    Publication date: January 28, 2016
    Inventor: Robert G. Matheny
  • Tissue Prostheses for Repairing, Reconstructing and Replacing Damaged or Diseased Biological Structures and Associated Tissue
    Publication number: 20160022868
    Abstract: Non-antigenic, resilient, bioremodelable, biocompatible tissue prostheses that can be engineered into a variety of shapes and used to repair, augment, reconstruct or replace damaged or diseased biological structures and associated tissue.
    Type: Application
    Filed: March 2, 2015
    Publication date: January 28, 2016
    Inventor: Robert G. Matheny
  • Extracellular matrix material valve conduit and methods of making thereof
    Patent number: 9241789
    Abstract: Methods for forming extracellular matrix valve conduits are disclosed. Extracellular matrix valve conduits produced using the disclosed methods are also disclosed. Methods of sterilizing and decellularizing extracellular matrix materials are also disclosed.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: January 26, 2016
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventors: Robert G Matheny, Christian L Gilbert
  • Extracellular matrix material conduits and methods of making and using same
    Patent number: 9226821
    Abstract: Extracellular matrix (ECM) valve conduits are disclosed. Methods for regenerating atrioventricular valves to replace defective atrioventricular valves within a heart of a subject using the ECM valve conduits are also disclosed. Methods of sterilizing and decellularizing an ECM material are also disclosed.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: January 5, 2016
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G. Matheny
  • Extracellular Matrix Encasement Structures and Methods
    Publication number: 20150359937
    Abstract: A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.
    Type: Application
    Filed: August 24, 2015
    Publication date: December 17, 2015
    Inventor: Robert G. Matheny
  • Extracellular Matrix Encasement Structures and Methods
    Publication number: 20150359935
    Abstract: A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.
    Type: Application
    Filed: August 24, 2015
    Publication date: December 17, 2015
    Inventor: Robert G. Matheny
  • Extracellular Matrix Constructs for Treating Damaged Biological Tissue
    Publication number: 20150359933
    Abstract: Extracellular matrix (ECM) constructs having a biodegradable support scaffold and an anchoring mechanism, which includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein. In a preferred embodiment, the support scaffold and anchoring mechanism comprise an ECM material. In some embodiments, the microneedles are also capable of administering a biologically active agent and/or a pharmacological composition to the engaged tissue.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Inventor: Robert G. Matheny
  • Extracellular Matrix Constructs for Treating Damaged Biological Tissue
    Publication number: 20150359932
    Abstract: Extracellular matrix (ECM) constructs having a biodegradable support scaffold and an anchoring mechanism, which includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein. In a preferred embodiment, the support scaffold and anchoring mechanism comprise an ECM material. In some embodiments, the microneedles are also capable of administering a biologically active agent and/or a pharmacological composition to the engaged tissue.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Inventor: Robert G Matheny
  • Extracellular Matrix (ECM) Structures for Tissue Regeneration
    Publication number: 20150359942
    Abstract: A multi-sheet extracellular matrix (ECM) structure for tissue regeneration, the ECM structure having joined first and second ECM sheet members and an agent dispersal network disposed between the sheets, the dispersal network being configured to receive and transfer a bioactive agent through the network and, when the ECM structure is attached to tissue, administer the bioactive agent to the tissue.
    Type: Application
    Filed: August 6, 2014
    Publication date: December 17, 2015
    Inventors: Robert G. Matheny, Craig N. Ferrante
  • Extracellular Matrix Encasement Structures and Methods
    Publication number: 20150359939
    Abstract: A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.
    Type: Application
    Filed: August 24, 2015
    Publication date: December 17, 2015
    Inventor: Robert G. Matheny
  • Extracellular Matrix Encasement Structures and Methods
    Publication number: 20150359938
    Abstract: A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.
    Type: Application
    Filed: August 24, 2015
    Publication date: December 17, 2015
    Inventor: Robert G. Matheny
  • Extracellular Matrix Constructs for Treating Damaged Biological Tissue
    Publication number: 20150359622
    Abstract: Extracellular matrix (ECM) constructs having a biodegradable support scaffold and an anchoring mechanism, which includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein. In a preferred embodiment, the support scaffold and anchoring mechanism comprise an ECM material. In some embodiments, the microneedles are also capable of administering a biologically active agent and/or a pharmacological composition to the engaged tissue.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Inventor: Robert G. Matheny
  • Articles for Tissue Regeneration with Biodegradable Polymer
    Publication number: 20150359934
    Abstract: The invention is also directed to particulate articles comprising extracellular matrix components that are encased in a biodegradable polymer composition. Methods of for treating damaged tissue and regenerating new tissue at sites of the damaged tissue by placing a particulate article in mammals are claimed.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Inventor: Robert G Matheny