Abstract: A bone graft containment device includes a body formed via one or more helical structures extending about a longitudinal axis of the body from a first end to a second end to define a channel extending longitudinally therethrough. The channel is configured to receive a bone graft or bone graft substitute material therein, the one or more helical structures formed of a material permitting the body to be one of expanded, compressed and curved to fill a target space of a target bone.

Abstract: An apparatus for measuring body core temperature includes a light guide with an internally reflective tube. The light guide is coupled to an earpiece, and has a lens or an aperture positioned at one of its ends. A sensor is positioned at the other end of the light guide, and a processor is coupled to the sensor. The sensor senses infrared radiation from an infrared source at the end of the light guide, and the processor determines a temperature of the infrared source at the end of the light guide via a transfer function that correlates a measure of the infrared radiation observed by the sensor and an effect of radiation of the light guide.

Abstract: An anchor assembly can include at least one anchor member, such as a pair of anchor members that are configured to be implanted in a target anatomical location in a first configuration, and can subsequently be actuated to an expanded configuration that secures the anchor members in the target anatomy. The anchor assembly can further include a connector member that attaches the pair of anchor members together across a gap so as to approximate the anatomical defect.

Abstract: A pressure test method, device, and system of using the same are described herein. One method includes an inflatable with an internally mounted pressure sensor assembly, measuring pressure values, associating the sensor to an identification reader to receive the pressure values from the pressure sensor, and notifying a user of the measured pressure.

Abstract: A compression screw comprising a threaded shaft and a head associated with the proximal end of the shaft. The head has a plurality of outwardly extending projections spaced from one another so as to define a plurality of recesses there between for receiving a screw drive in such a way that rotational force may be transferred from the screw drive to the screw. The projections of the head may be provided with suture fixation holes or a suture coupling may be positioned over the shaft so as to extend between the projections of the head.

Abstract: A guide assembly for facilitating placement of a fixation member within a medullary canal of a radius is provided. According to one embodiment, a guide assembly includes a guide fastener configured to attach to a fixation member and a guide member configured to receive the guide fastener such that the guide member is secured to the fixation member. The guide assembly also includes an interchangeable distal guide member configured to engage and be disengaged from the guide member. The distal guide member defines a plurality of fastener guide openings for guiding respective fasteners through a plurality of fastener openings defined in the fixation member.

Abstract: A device for measuring body core temperature includes a light guide. The light guide is coupled to an earpiece. A first sensor is positioned at a first end of the light guide, and a second sensor is positioned at a second end of the light guide. A processor is coupled to the first sensor and the second sensor. The first sensor senses infrared radiation from an infrared source at the second end of the light guide, and the second sensor measures a temperature of the light guide at the second end of the light guide. The processor determines a temperature of the infrared source at the second end of the light guide by compensating for infrared radiation due to a thermal gradient of the light guide via a regression analysis across a range of ambient temperatures of the light guide.

Abstract: An apparatus for measuring body core temperature includes a light guide. The light guide can be coupled to an earpiece, or it can be a standalone device. The apparatus also includes a sensor positioned at one end of the light guide, and a processor coupled to the sensor. The sensor is operable to sense infrared radiation from an infrared source at the opposite end of the light guide. The processor is operable to determine a temperature of the infrared source at the opposite end of the light guide via a transfer function that correlates a measurement of the infrared radiation observed by the sensor and an effect of radiation of the light guide.

Abstract: A flame detector includes an infrared detector and a first window covering the infrared detector. A second window is positioned in front of the first window. The flame detector is adapted to reject light having a wavelength below approximately 2 ?m and to reject light having a wavelength above approximately 6 ?m, allowing detection of flame from multiple sources. In variations, the windows in combination with the infrared detector may provide the rejection or a band pass filter provides the rejection. Still further variations utilize notch filters or a band reject filter to provide notches of light to the infrared detector corresponding to the wavelength of different flame sources to be detected.

Abstract: An insertion instrument is configured to eject a pair of anchor bodies across an anatomical gap so as to approximate the gap. The insertion instrument can include a single cannula that retains the pair of anchor bodies in a stacked relationship, or a pair of adjacent cannulas that each retain respective anchor bodies. The insertion instrument can be actuated so as to eject the anchor bodies into respective target anatomical locations.

Abstract: A device for containing bone graft material includes a mesh outer sleeve extending longitudinally from a proximal end to a distal end and sized and shaped to correspond to a profile of an outer surface of a target bone. The outer sleeve includes a longitudinal slot extending along a length thereof. The device also includes a mesh inner sleeve connected to an interior surface of the outer sleeve via at least one strut so that a bone graft collecting space is defined therebetween. The inner sleeve is sized and shaped to correspond to a profile of a medullary canal of the target bone. In addition, the device includes an interstitial mesh extending radially away from an exterior surface of the inner sleeve toward an interior surface of the outer sleeve to hold graft material in the bone graft collecting space.

Abstract: A device for containing a graft material includes an outer member formed via an outer mesh sheet biased toward a coiled configuration in which the outer mesh sheet is coiled about a longitudinal axis thereof so that, when the outer member is positioned about separated portions of a target bone in an operative position, the outer member reverts to the coiled configuration and contracts about and engages the separated portions. The device also includes an inner member formed via an inner mesh sheet coiled about a longitudinal axis thereof. The inner member is movable between a first biased coiled configuration and a second coiled configuration. A diameter of the inner member in the first coiled configuration is larger than a diameter of the inner member in the second coiled configuration.

Abstract: An insertion instrument is configured to eject a pair of anchor bodies across an anatomical gap so as to approximate the gap. The insertion instrument can include a single cannula that retains the pair of anchor bodies in a stacked relationship, or a pair of adjacent cannulas that each retain respective anchor bodies. The insertion instrument can be actuated so as to eject the anchor bodies into respective target anatomical locations.

Abstract: Provided herein is technology relating to deuterated amlexanox and particularly, but not exclusively, to compositions comprising deuterated amlexanox, methods of producing deuterated amlexanox, and uses of deuterated amlexanox.

Abstract: Provided herein is technology relating to deuterated amiexanox and particularly, but not exclusively, to compositions comprising deuterated amiexanox, methods of producing deuterated amiexanox, and uses of deuterated amiexanox. Provided herein are deuteratecl amiexanox compounds for the treatment of obesity, insulin resistance, diabetes, and steatosis. In addition, the deuterated compounds are anti-inflammatory antiallergic immunomodulators. e.g., for the treatment of diseases associated with inflammation. The deuterium kinetic isotope effect associated with placing deuterium at the site of metabolic derivatization slows metabolic derivatization and thus increases the lifetime of the active drug in vivo.

Abstract: Embodiments relate generally to systems and methods for determining end of service life for a respirator cartridge by comparing the gas levels sensed at two or more sample points within the cartridge. Sample streams may run from the sample points to a gas sensor, wherein a valve may control the flow between the sample streams and the gas sensor.

Abstract: Provided herein is technology relating to deuterated amiexanox and particularly, but not exclusively, to compositions comprising deuterated amiexanox, methods of producing deuterated amiexanox, and uses of deuterated amiexanox. Provided herein are deuteratecl amiexanox compounds for the treatment of obesity, insulin resistance, diabetes, and steatosis. In addition, the deuterated compounds are anti-inflammatory antiallergic immunomodulators. e.g., for the treatment of diseases associated with inflammation. The deuterium kinetic isotope effect associated with placing deuterium at the site of metabolic derivatization slows metabolic derivatization and thus increases the lifetime of the active drug in vivo.

Abstract: An anchor assembly can include at least one anchor member, such as a pair of anchor members that are configured to be implanted in a target anatomical location in a first configuration, and can subsequently be actuated to an expanded configuration that secures the anchor members in the target anatomy. The anchor assembly can further include a connector member that attaches the pair of anchor members together across a gap so as to approximate the anatomical defect.

Abstract: Embodiments may comprise personal protective equipment with integrated physiological monitoring. Some embodiments may relate specifically to in-ear devices (such as hearing protection and/or communication devices) having one or more physiological sensors for early monitoring for heat related illnesses. Several embodiments may incorporate a temperature sensor and a speaker into such in-ear device.

Abstract: An anchor assembly can include at least one anchor member, such as a pair of anchor members that are configured to be implanted in a target anatomical location in a first configuration, and can subsequently be actuated to an expanded configuration that secures the anchor members in the target anatomy. The anchor assembly can further include a connector member that attaches the pair of anchor members together across a gap so as to approximate the anatomical defect.