Abstract: The present invention provides a fault prediction and condition-based repair method of an urban rail train bogie. An optimum service life distribution model of a framework, a spring device, a connecting device, a wheel set and axle box, a driving mechanism, and a basic brake device of a bogie is determined by adopting a method based on survival analysis; a reliability characteristic function of each subsystem is obtained; then, a failure rate of each subsystem of the bogie is calculated by adopting a neural network model optimized by an evolutionary algorithm; and finally, proportional risk modelling is conducted by taking the failure rate and safe operation days of each subsystem of the bogie as concomitant variables; and on the basis of cost optimization, thresholds and control limits for condition-based repair of a bogie system are obtained.

Abstract: A PET tracer for imaging tumors or neurological disorders that overexpress L-PGDS enzyme is provided. The present invention have prepared a glutathione conjugate of fluorine-18-labeled fluorobutyl ethacrynic amide using an acceptable amount of radioactivity that is capable of binding to L-PGDS and can be used for in vitro and in vivo imaging studies.

Abstract: Embodiments of the present invention provide methods, program products, and systems to increase efficiency in message oriented middleware. Embodiments of the present invention can, responsive to receiving from an application an open request for a queue alias of a queue manager, provide to the application target cache information which includes a target name and a change flag count associated with the queue alias. Embodiments of the present invention can, responsive to receiving a message from the application that includes respective target cache information including a target name and a change flag count, determine a target location, wherein if the change flag count of the received message matches a current change flag count of the queue alias, the determined target location is a target location associated with the received target name.

Abstract: A waterproof keyboard includes a lower housing, a circuit membrane disposed on the lower housing, a pressure plate disposed on the circuit membrane, an elastomer member, an upper housing disposed on the elastomer member and a plurality of key caps disposed on the upper housing. The pressure plate has a main body formed with a plurality of openings and ridges. The elastomer member has a plurality of switch domes disposed in the openings correspondingly, a base layer disposed on the main body, and a plurality of raised portions disposed on the ridges respectively. The ridges of the pressure plate presses tightly to the underside of the raised portions. The pressure plate is constructed to evenly support the elastomer member.

Abstract: The present invention provides a method of preparing [123I]Iodooctyl fenbufen amide with a radiochemical yield of 15%, a specific activity of 37 GBq/?mol and radiochemical purity of 95%. The present invention further provides a method of applying [123I]Iodooctyl fenbufen amide as tracer of single photon emission computer tomography (SPECT) to estimate the distribution of cyclooxygenase. By the binding characteristics of the iodine isotope-labeled compounds and the positive correlation of inflammation to tumor lesion, the present invention can estimate the tumor development and metastasis.

Abstract: The invention discloses a method for production of polyhydroxybutyrate-co-polyhydroxyvalerate (PHBV) by recombinant Escherichia coli harboring plasmid containing both phaCAB and prpE. Different percentage of hydroxyvalerate can be obtained from the recombinant E. coli when cultivated in the medium containing different concentrations of propionic acid. In this patent, we provide a method that integrated all of the genes (i.e. phaCAB, vgb and prpE) required for PHBV production into a single plasmid. The plasmids were then transformed into an E. coli host. Results showed that PHBV can be produced by this recombinant E. coli, and the ration of HV to HB in the co-polymers can be regulated by addition of different concentrations of propionic acid in the medium. The percentage of HV in the co-polymers can be adjusted from about 3% up to more than 35%.

Abstract: A tumor radiation probe of iodine-123 marker thymidine (FLT) analogue [123I]-IaraU is disclosed. Commercial available uridine is used as the raw material for the synthesis of the precursor. A radioactive iodine-123 is marked on an alkaline group of uridine to obtain [123I]-IaraU, which is distinguishable from [18F]-FLT marking 18F on a glycosyl group to obtain a novel tumor radiation probe. The marking procedures include mixing the marker precursor with Na [123I] solution, acetic acid and hydrogen peroxide solution, and the solution of chloroform and sodium hydroxide. The sonication time increases from 1 minute to 10 minutes, so that [123I]-IaraU has radiologically chemical purity of higher than 98% and radiological specific activity of not less than 0.196 GBq/umole, and the yield can increase from 8% to 40%. Its radioactive specific activity, yield and purity reach to the degree for the use in biological experiments, while reducing production cost.

Abstract: The present invention provides a method of preparing [123I]Iodooctyl fenbufen amide with a radiochemical yield of 15%, a specific activity of 37 GBq/?mol and radiochemical purity of 95%. The present invention further provides a method of applying [123I]Iodooctyl fenbufen amide as tracer of single photon emission computer tomography (SPECT) to estimate the distribution of cyclooxygenase. By the binding characteristics of the iodine isotope-labeled compounds and the positive correlation of inflammation to tumor lesion, the present invention can estimate the tumor development and metastasis.

Abstract: A tumor radiation probe of iodine-123 marker thymidine (FLT) analogue [123I]-IaraU is disclosed. Commercial available uridine is used as the raw material for the synthesis of the precursor. A radioactive iodine-123 is marked on an alkaline group of uridine to obtain [123I]-IaraU, which is distinguishable from [18F]-FLT marking 18F on a glycosyl group to obtain a novel tumor radiation probe. The marking procedures include mixing the marker precursor with Na [123I] solution, acetic acid and hydrogen peroxide solution, and the solution of chloroform and sodium hydroxide. The sonication time increases from 1 minute to 10 minutes, so that [123I]-IaraU has radiologically chemical purity of higher than 98% and radiological specific activity of not less than 0.196 GBq/umole, and the yield can increase from 8% to 40%. Its radioactive specific activity, yield and purity reach to the degree for the use in biological experiments, while reducing production cost.

Abstract: The invention discloses a method for production of polyhydroxybutyrate-co-polyhydroxyvalerate (PHBV) by recombinant Escherichia coli harboring plasmid containing both phaCAB and prpE. Different percentage of hydroxyvalerate can be obtained from the recombinant E. coli when cultivated in the medium containing different concentrations of propionic acid. In this patent, we provide a method that integrated all of the genes (i.e. phaCAB, vgb and prpE) required for PHBV production into a single plasmid. The plasmids were then transformed into an E. coli host. Results showed that PHBV can be produced by this recombinant E. coli, and the ration of HV to HB in the co-polymers can be regulated by addition of different concentrations of propionic acid in the medium. The percentage of HV in the co-polymers can be adjusted from about 3% up to more than 35%.

Abstract: A waterproof keyboard includes a lower housing, a circuit membrane disposed on the lower housing, a pressure plate disposed on the circuit membrane, an elastomer member, an upper housing disposed on the elastomer member and a plurality of key caps disposed on the upper housing. The pressure plate has a main body formed with a plurality of openings and ridges. The elastomer member has a plurality of switch domes disposed in the openings correspondingly, a base layer disposed on the main body, and a plurality of raised portions disposed on the ridges respectively. The key caps abut to the switch domes respectively. The raised portions of the elastomer member are fixed to the bottom surface of the upper housing, while the ridges of the pressure plate presses tightly to the underside of the raised portions. The pressure plate is constructed to evenly support the elastomer member.

Abstract: The present invention provides a compound selected from compound of formula (I), pharmaceutically acceptable salts of compound of formula (I), and pharmaceutically acceptable prodrugs of compound of formula (I), and a composition comprising the compound of the above and a pharmaceutically acceptable excipient. The present invention also provides a method for preparing a compound that activates natural killer T cells.

Abstract: A testing device suitable for a testing apparatus with light inspection of a display panel is provided, in which the testing device includes a main part and two contact parts. The testing device is fixed to the testing apparatus with light inspection by the main part. Two contact parts are respectively extended from two ends of the main part along a first direction, and each of the contact parts has a plurality of tips. The tips of each contact part have different heights. Besides, a testing apparatus is also provided. Therefore, the abovementioned testing device and the testing apparatus are able to drastically extend the user lifetime, improve the inspection accuracy and save cost.

Abstract: A satellite antenna package is provided. The satellite antenna package includes a receiving structure, an antenna device and a cable. A recess and a groove are formed on the receiving structure, and the recess communicates with the groove. The antenna device is disposed in the recess. The cable connects to the antenna device, wherein the cable is connected with the antenna device and partially disposed in the groove, travels along an edge of the receiving structure, and surrounds the antenna device.

Abstract: A method includes receiving a data unit, determining whether a current state, associated with a deterministic finite automata (DFA) that includes a portion of states in a bitmap and a remaining portion of states in a DFA table, is a bitmap state or not, and determining whether a value corresponding to the data unit is greater than a threshold value, when it is determined that the current state is not a bitmap state. The method further includes determining whether the current state is insensitive, when it is determined that the value corresponding to the data unit is greater than the threshold value, where insensitive means that each next state is a same state for the current state, and selecting a default state, as a next state for the current, when it is determined that the current state is insensitive.

Abstract: A port detection and protection circuit utilizes a voltage detection circuits to output a detection signal according to a voltage difference between the tip signal and the ring signal and utilizes a ring detection circuit to output another detection signal according to a voltage difference between a Subscriber Line Interface Circuit (SLIC) tip signal and a SLIC ring signal signaling an incoming call. In addition, the port detection and protection circuit utilizes at least one logic component to output logic signals according to the detection signals. The port detection and protection circuit further switches a loop of a tip wire, a ring wire and the SLIC on or/and off based on logic signals, and issues an alarm according to the logic signals.

Abstract: A testing device suitable for a testing apparatus with light inspection of a display panel is provided, in which the testing device includes a main part and two contact parts. The testing device is fixed to the testing apparatus with light inspection by the main part. Two contact parts are respectively extended from two ends of the main part along a first direction, and each of the contact parts has a plurality of tips. The tips of each contact part have different heights. Besides, a testing apparatus is also provided. Therefore, the abovementioned testing device and the testing apparatus are able to drastically extend the user lifetime, improve the inspection accuracy and save cost.

Abstract: A testing device suitable for a testing apparatus with light inspection of a display panel is provided, in which the testing device includes a main part and two contact parts. The testing device is fixed to the testing apparatus with light inspection by the main part. Two contact parts are respectively extended from two ends of the main part along a first direction, and each of the contact parts has a plurality of tips. The tips of each contact part have different heights. Besides, a testing apparatus is also provided. Therefore, the abovementioned testing device and the testing apparatus are able to drastically extend the user lifetime, improve the inspection accuracy and save cost.

Abstract: The present invention discloses a pharmaceutical composition for inhibiting increase of immunoglobulin A (IgA) comprising ?-glucan and a pharmaceutical acceptable carrier. The ?-glucan is extracted from Saccharomyces Cerevisiae, and the effective dose of the ?-glucan is 300-450 mg/70 kg of body weights/per day, preferably, 350-400 mg/70 kg of body weights/day.

Abstract: A process for synthesizing and screening solution phase derived libraries of fenbufen and ethacrynic acid is provided in the present invention. Compounds in the present invention having cytotoxicities are useful for a variety of therapeutic applications.