Abstract: A touch panel has a substrate having a display region and a peripheral region, a touch sensing electrode disposed in the display region of the substrate, and a peripheral circuit disposed in the peripheral region of the substrate. The touch sensing electrode is electrically connected to the peripheral circuit, and the touch sensing electrode layer includes a first portion of a patterned metal nanowire layer. The peripheral circuit includes a patterned conductive layer and a second portion of the metal nanowire layer. At least a non-conductive material of the conductive layer is between the peripheral circuit and a second peripheral circuit.

Abstract: The present application relates to methods for detecting a tandem repeat in a nucleic acid sequence under isothermal conditions using primers.

Abstract: The invention relates to pharmaceutical compositions comprising a conjugate of a porphyrin (e.g., PpIX) and a recombinant protein. The pharmaceutical compositions of the invention may be used in photodynamic therapy. The invention also relates to methods of producing such pharmaceutical compositions and to methods of using such pharmaceutical compositions in the treatment of diseases, such as cancer.

Abstract: An information processing method based on contextual signals and a prefrontal cortex-like network includes: selecting a feature vector extractor based on obtained information to perform feature extraction to obtain an information feature vector; inputting the information feature vector into the prefrontal cortex-like network, and performing dimensional matching between the information feature vector and each contextual signal in an input contextual signal set to obtain contextual feature vectors to constitute a contextual feature vector set; and classifying each feature vector in the contextual feature vector set by a feature vector classifier to obtain classification information of the each feature vector to constitute a classification information set. An information processing system based on contextual signals and a prefrontal cortex-like network includes an acquisition module, a feature extraction module, a dimensional matching module, a classification module and an output module.

Abstract: Provided is a method for reducing fat accumulation in and oxidative damage to liver cells by using a green mango extract. Also provided is a method for reducing fat accumulation in liver cells by using compounds of hydrolyzable tannins isolated from the green mango extract.

Abstract: An information processing method based on contextual signals and a prefrontal cortex-like network includes: selecting a feature vector extractor based on obtained information to perform feature extraction to obtain an information feature vector; inputting the information feature vector into the prefrontal cortex-like network, and performing dimensional matching between the information feature vector and each contextual signal in an input contextual signal set to obtain contextual feature vectors to constitute a contextual feature vector set; and classifying each feature vector in the contextual feature vector set by a feature vector classifier to obtain classification information of the each feature vector to constitute a classification information set. An information processing system based on contextual signals and a prefrontal cortex-like network includes an acquisition module, a feature extraction module, a dimensional matching module, a classification module and an output module.

Abstract: A method for at least one of increasing the synthesis of melatonin and promoting the secretion of melatonin is provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I): A method for at least one of treating diseases related to neurometabolic disorder, preventing diseases related to neurometabolic disorder, regulating appetite, regulating mood, regulating vasoconstriction, regulating hemostatic function and regulating immune response is also provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I) as described above.

Abstract: A touch panel includes a substrate having a display area and a peripheral area. A peripheral circuit is disposed in the peripheral area. The peripheral circuit comprises at least one bonding pad made of a metal layer. A plurality of touch sensing electrodes is disposed in the display area. The plurality of touch sensing electrodes is made of a metal nanowire layer, a film layer disposed on the metal nanowire layer, and a negative-type photosensitive layer disposed on the film layer. The plurality of touch sensing electrodes is electrically connected to the peripheral circuit.

Abstract: Automated devices send messages of a first batch sequence individually to a target queue of a receiving node of a cluster of server nodes, the messages having a different sequence number indicative of their relative positions within the batch sequence, and each is associated with a first logic unit of work identifier. In response to determining that a message counter meets a threshold, a force commit packet is generated to include the sequence number of the last batch message sent to the target queue. If the force commit packet sequence number is not the last position number within the batch sequence, a second logic unit of work identifier is associated with a subset sequence of the batch of messages having sequence numbers spanning from the first number to the force commit packet sequence number, and the subset sequence messages are committed to the receiving node target queue.

Abstract: The direct patterning method includes: providing a substrate having a display area and a peripheral area, which a peripheral circuit having a bonding pad is disposed on the peripheral area; sequentially disposing a metal nanowire layer, a pre-cured film layer and a negative-type photosensitive layer thereon; performing a photolithography step; and curing the pre-cured film layer. The photolithography step includes exposing the negative-type photosensitive layer to define a removal region and a reserved region; and removing the negative-type photosensitive layer, the pre-cured film layer and the metal nanowire layer in the removal region by using a developer, such that a touch sensing electrode is fabricated in the display area and the bonding pad is exposed.

Abstract: The present disclosure relates to recombinant hemoglobins with improved oxygen carrying capacity and methods of preparation and use thereof. The present disclosure also relates to a pharmaceutical composition including the recombinant hemoglobin useful for treating oxygen deficiency related diseases or conditions, such as stroke, hemorrhagic shock, peripheral arterial disease (PAD), acute mountain sickness (AMS), cancer, and Parkinson's disease (PD).

Abstract: The present disclosure relates to recombinant hemoglobins with improved oxygen carrying capacity and methods of preparation and use thereof. The present disclosure also relates to a pharmaceutical composition including the recombinant hemoglobin useful for treating oxygen deficiency related diseases or conditions, such as stroke, hemorrhagic shock, peripheral arterial disease (PAD), acute mountain sickness (AMS), cancer, and Parkinson's disease (PD).

Abstract: A method for at least one of increasing the synthesis of melatonin and promoting the secretion of melatonin is provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I): A method for at least one of treating diseases related to neurometabolic disorder, preventing diseases related to neurometabolic disorder, regulating appetite, regulating mood, regulating vasoconstriction, regulating hemostatic function and regulating immune response is also provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I) as described above.

Abstract: A method for at least one of increasing the synthesis of melatonin and promoting the secretion of melatonin is provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I): A method for at least one of treating diseases related to neurometabolic disorder, preventing diseases related to neurometabolic disorder, regulating appetite, regulating mood, regulating vasoconstriction, regulating hemostatic function and regulating immune response is also provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I) as described above.

Abstract: A method for at least one of increasing the synthesis of melatonin and promoting the secretion of melatonin is provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I): A method for at least one of treating diseases related to neurometabolic disorder, preventing diseases related to neurometabolic disorder, regulating appetite, regulating mood, regulating vasoconstriction, regulating hemostatic function and regulating immune response is also provided, wherein the method comprises administering to a subject in need an effective amount of a compound of formula (I) as described above.

Abstract: A two-layer gradient coating article is provided that is operable to cause selective adhesion and directional migration of endothelial cells. The first layer includes cell-resisting polymers that repels cells, the second layer includes one layer of peptides that has affinity to and binds specifically to endothelial cells. Furthermore, the peptides are distributed in a gradient in which attached ECs migrate towards the direction of increased concentration, thus enriching the ECs to a desired locus. The combination of a cell-repelling layer and a graded affinity peptide produces a unique result of selective adhesion, directional migration, thus local enrichment of endothelial cells. A method for using such gradient coating article and its potential use in treating cardiovascular diseases are also provided. The invention provides an inexpensive, stable and effective means for attracting ECs to desirable locations.

Abstract: The invention is directed to methods of converting a carboxylic acid group in a compound, via a redox active ester, to a corresponding boronic ester by treatment with bis(pinacolato)diboron-alkyllithium complex in the presence of a ligand, a Ni(11) salt or a copper salt, and an Mg(11) salt, in the presence of an alkyllithium or a lithium hydroxide or alkoxide salt. The product pinacolato boronate ester can be cleaved to provide a boronic acid. The invention is also directed to methods of preparing various compounds of medical value comprising boronic acid groups, and to novel boronic-acid containing compounds of medicinal value, including an atorvastatin boronic acid analog, a vancomycin aglycone boronic acid analog, and boronic acid containing elastase inhibitors mCBK319, mCBK320, mCBK323, and RPX-7009.

Abstract: A touch panel includes a substrate, a photosensitive layer, a metal nanowire layer and a photosensitive conductive layer. The metal nanowire layer and the photosensitive layer are formed on a display area and a peripheral area of the substrate. The photosensitive conductive layer is formed on the metal nanowire layer on the peripheral area. A removal region and a reserved region of both the photosensitive conductive layer and the photosensitive layer are defined by an exposure process. At the display area, the photosensitive layer and the metal nanowire layer in the removal region are removed by a developer to form a touch sensing electrode. At the peripheral area, the photosensitive conductive layer, the photosensitive layer and the metal nanowire layer in the removal region are removed by a developer to form a peripheral conductive trace. The touch sensing electrode is electrically connected to the peripheral conductive trace.

Abstract: Provided is a method for reducing fat accumulation in and oxidative damage to liver cells by using a green mango extract. Also provided is a method for reducing fat accumulation in liver cells by using compounds of hydrolyzable tannins isolated from the green mango extract.

Abstract: The present disclosure provides an inhibitor for inhibiting or disrupting biofilm and use thereof. Specifically, the present disclosure an application of a PsIG protein and a coding sequence thereof in inhibiting or disrupting a biofilm of a microorganism. The present disclosure also provides a composition and a preparation containing the PsIG protein to inhibit or disrupt a biofilm of a microorganism. The experiment shows that PsIG can effectively inhibit or disrupt a biofilm of Pseudomonas species, suggesting the great potential of PsIG in clinical and environmental fields.