Patents by Inventor Shinji Takeoka

Shinji Takeoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040162261
    Abstract: Provided is a zwitterionic lipid compound represented by formula (I) given below: 1
    Type: Application
    Filed: February 23, 2004
    Publication date: August 19, 2004
    Applicant: OXYGENIX CO., LTD.
    Inventors: Eishun Tsuchida, Shinji Takeoka, Keitaro Sou, Katsura Mori
  • Publication number: 20040057988
    Abstract: A method for preparing a vesicle dispersion wherein a water-soluble substance is encupsulated in the vesicle, which comprises successively performing: a step of dispersing at least one lipid in an aqueous medium to pre-construct a vesicle dispersion, a step of drying the pre-constructed vesicles to obtain dried vesicle, a step of re-dispersing the dried vesicles in an aqueous solution of the water-soluble substance, and a step of passing the resultant vesicle dispersion through a filter. The method enables the efficient and simple preparation of safe vesicles with a useful substance in high concentration encupsulated therein, with a narrow size distribution, in high yield.
    Type: Application
    Filed: July 2, 2003
    Publication date: March 25, 2004
    Inventors: Eishun Tsuchida, Shinji Takeoka, Keitaro Sou, Taro Endo, Yoshiyasu Naito
  • Publication number: 20040028638
    Abstract: As a negatively charged lipid that can stably add negative charges to the surface of vesicles without side effects, the carboxyl acid-type lipid of the following general formula [1] 1
    Type: Application
    Filed: July 2, 2003
    Publication date: February 12, 2004
    Inventors: Eishun Tsuchida, Shinji Takeoka, Keitaro Sou, Haruki Ohkawa, Katsura Mori
  • Publication number: 20020137221
    Abstract: There is provided a method for preserving an oxygen infusion comprising a suspension containing hemoglobin or a heme derivative contained in molecular assemblies suspended in a aqueous medium, comprising modifying the molecular assemblies with polyoxyethylene, and making the hemoglobin or the heme derivative to a deoxy-type by removing oxygen from the suspension.
    Type: Application
    Filed: March 7, 2002
    Publication date: September 26, 2002
    Applicant: Japan Science and Technology Corporation
    Inventors: Eishun Tsuchida, Hiromi Sakai, Kenichi Tomiyama, Shinji Takeoka, Keitaro Sou
  • Publication number: 20020120096
    Abstract: An amphiphilic compound having a dendritic branch structure represented by general formula (I): 1
    Type: Application
    Filed: February 27, 2002
    Publication date: August 29, 2002
    Applicant: Japan Science and Technology Corporation
    Inventors: Eishun Tsuchida, Shinji Takeoka, Keitaro Sou, Haruki Ohkawa
  • Publication number: 20020095108
    Abstract: Disclosed is a method and apparatus for regenerating an oxygen-binding ability by reducing the methemoglobin contained in hemoglobin-vesicle by light irradiation. This method comprises adding electron donors such as amino acids, saccharides, alcohols, and/or flavin derivatives in appropriate amounts to the inner aqueous phase of the hemoglobin-vesicle, applying light to the vesicle when the content of methemoglobin increases as a result of oxidation of hemoglobin, thereby reducing the metohemoglobin. In this manner, the oxygen-binding ability is recovered, thereby maintaining the function of the hemoglobin-vesicle.
    Type: Application
    Filed: February 12, 2002
    Publication date: July 18, 2002
    Applicant: Japan Science and Technology Corporation
    Inventors: Eishun Tsuchida, Hiromi Sakai, Hiroto Onuma, Shinji Takeoka
  • Patent number: 5986046
    Abstract: An oxidant solution for synthesizing a heat-resistant electroconductive polymer, composed of a solution of a non-protonic organic solvent and an oxidant of the organic compound iron salt expressed by the following formula:Fe.sup.3+O [(X)L--(M)m--(Y.sup.-)n]pH.sup.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: November 16, 1999
    Assignee: NEC Corporation
    Inventors: Toshihiko Nishiyama, Takashi Fukaumi, Atushi Kobayashi, Masashi Ohi, Yoshihiko Saiki, Kazuaki Fukushima, Tomitaro Hara, Shinji Takeoka, Kimihisa Yamamoto, Eishun Tuchida
  • Patent number: 5951840
    Abstract: The solid electrolytic capacitor comprises a sealed capacitor element having, as a solid electrolyte layer, a heat resistant conductive layer formed on a dielectric oxide film. The heat resistant conducting polymer layer contains water, and the capacitor element inside is substantially oxygen-free. A cathode conductive layer is provided on the capacitor element and then both an external cathode lead and an external anode lead are mounted on the capacitor element. Water is supplied to the conducting polymer layer of the capacitor element such that the conducting polymer layer inside contains water. The capacitor element is then sealed such that water is held within the heat resistant conducting polymer layer and that the capacitor element inside is substantially oxygen-free. The step of supplying water is carried out by dipping the heat resistant conducting polymer layer in water or heavy water or exposed to water-containing inert gas.
    Type: Grant
    Filed: December 28, 1995
    Date of Patent: September 14, 1999
    Assignee: NEC Corporation
    Inventors: Takashi Fukaumi, Toshihiko Nishiyama, Atsushi Kobayashi, Masashi Ohi, Eishun Tsuchida, Kumihisa Yamamoto, Shinji Takeoka, Yoshitaka Fujishima
  • Patent number: 5472951
    Abstract: An oligosaccharide lipid is provided which has 2 to 20 saccharide units, and has a hydrophobic group linked by an ether linkage to an anomer carbon on a reducing end group. A stabilizer for a phospholipid vesicle is also provided which comprises an oligosaccharide derivative having 2 to 20 saccharide units, and having a hydrophobic group linked by an amide linkage or an ether linkage to an anomer carbon on a reducing end group constituted of an aldose.
    Type: Grant
    Filed: March 9, 1993
    Date of Patent: December 5, 1995
    Assignee: Chiba Flour Milling Co., Ltd.
    Inventors: Akihisa Saitoh, Kiyoshi Yoshimura, Takanao Suzuki, Mikimasa Takisada, Shinji Takeoka, Hiromi Sakai, Eishun Tsuchida
  • Patent number: 5160740
    Abstract: The present invention relates to a micromolecular endoplasmic reticulum which comprises a polymer obtained by polymerization of a mixture containing one or more polymerizable phospholipids, cholesterol and one or more polymerizable fatty acid. The macromolecular endoplasmic reticulum in which surface charge is fixed to negative can be used as a carrier of medicine, enzyme, hemoglobin, etc. in industrial fields or medical fields.
    Type: Grant
    Filed: April 27, 1990
    Date of Patent: November 3, 1992
    Assignee: Nippon Oil & Fats Co., Ltd.
    Inventors: Etsuo Hasegawa, Shinji Takeoka, Hiroyuki Ohno, Hiroyuki Nishide, Eishun Tsuchida
  • Patent number: 5135618
    Abstract: A process for manufacturing a solid state electrolytic capacitor having on an anode a dielectric coating layer and a solid state electrolytic layer, comprises the steps of forming a conductive polymer compound layer as the solid state electrolytic layer, and subsequently forming the dielectric coating layer by anodizing.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: August 4, 1992
    Assignee: NEC Corporation
    Inventors: Yoshihiko Saiki, Eishun Tsuchida, Kimihisa Yamamoto, Shinji Takeoka