Abstract: Sorbent for filtering a coolant in immersion cooling systems, such as those used to cool electronic components. Sorbent may comprise activated carbon sorbent materials that have a bulk oxygen content of about 1 wt. % to about 5 wt. %, a moisture level of at most about 1.5 wt. %, and a molasses number of at least about 150. Sorbents may be contained within an enclosure to convey coolant therethrough to remove conductive contaminants from the coolant.

Abstract: An integrated circuit for use in a first vehicle may include: an interface circuit that communicates with a second integrated circuit in a second vehicle; and a processing circuit. During operation, the processing circuit may determine that the second vehicle has better situational awareness for a portion of a road or an environment proximate to the road than the first vehicle, where the second vehicle is proximate to the first vehicle. Then, the processing circuit may dynamically establish, with the second integrated circuit, a communication pairing with the second vehicle. Moreover, the integrated circuit may exchange, via the pairing, information with the second integrated circuit. For example, the exchanged information may include or may specify: measurement data, one or more detected objects, one or more object identifiers, seed information for a detection technique (such as a priori information), and/or a priority or urgency of the exchanged information.

Abstract: Some embodiments provide a non-transitory machine-readable medium that stores a program. The program receives a request for questions associated with a location and a category. The program also identifies a matrix, a hierarchy of locations associated with the matrix, and a hierarchy of categories associated with the matrix. The program further determines an aggregate collection of questions from a plurality of sets of questions based on the matrix, the hierarchy of locations, and the hierarchy of categories. The program also generates the aggregate collection of questions.

Abstract: An indicator system for a surgical robotic system for indicating a state of at least a portion of patient anatomy, the surgical robotic system comprising a robot having abase and an arm extending from the base, the arm holding an endoscope at an end of the arm distal from the base, the endoscope being configured for insertion into a body cavity of the patient for observing a surgical site internal to a body of the patient, the indicator system comprising: a receiver configured to receive video data of at least a portion of patient anatomy at the surgical site from the endoscope; and a processor configured to:detect a spatio-temporal change in a pixel region of the received video data; identify, in response to the detected spatio-temporal change, a parameter of the patient anatomy; generate a health indicator indicative of the identified parameter or indicative of a profile of the identified parameter; and output the generated health indicator.

Abstract: An optoacoustic probe for optoacoustic imaging of a tissue is provided. The probe has a distal end operable to contact the tissue and a proximal end. A transducer assembly is configured to receive optoacoustic return signals. An optical window is configured to carry light along a light path to the tissue. The housing comprises a distal portion that has a probe face that includes an acoustic opening into which the transducer assembly is disposed and an optical opening into which the optical window is disposed. The transducer assembly and the optical window extend proximally from the probe face. A gasket is disposed within the optical opening at the probe face and extends at least partially around the optical window. The gasket is configured to form an optoacoustic barrier to at least partially optically and acoustically isolate at least a portion of the optical window from the housing of the probe.

Abstract: A method of manufacturing a composite structure includes accessing design data for the composite structure that is manufactured according to a process including forming a layup of plies of fibers using a machine tool. The method includes applying the design data to an ANN classifier to classify a localized inconsistency of a type of inconsistency on the composite structure, the localized inconsistency spatially referenced to a location on the composite structure. The method includes performing a root cause analysis to identify one or more of process parameters as a potential cause of the type of inconsistency, and modifying one or more of the geometric model, the layup design, or values of the one or more of the process parameters to address the potential cause.

Abstract: The present disclosure provides industrially scalable methods of making (Z)-endoxifen or a salt thereof, crystalline forms of endoxifin, and compositions comprising them. The present disclosure also provides methods for treating hormone-dependent breast and hormone-dependent reproductive tract disorders.

Abstract: The techniques disclosed herein provide a synchronization engine that operates in conjunction with a service worker to dynamically store and update a working set of user data and single page application (SPA) resources from a network server to a user device. The working set can be hosted across several domains and identified by association with a user account. Accordingly, the synchronization engine retrieves the working set from the network server to enable offline execution of the single page applications. As such, subsequent requests for interacting with a single page application are then serviced by the synchronization engine using the working set retrieved from the network server. For instance, the service worker can bind user data to the application resources to enable progressive rendering through an application controller using locally available resources. In this way, the disclosed system provides a consistent user experience irrespective of network connectivity.

Abstract: Certain embodiments provide a vitrectomy probe including a housing, an actuator disposed inside the housing, a cutter coupled to the actuator and extending from the housing and an air turbine disposed inside the housing. The air turbine includes a rotor and a plurality of turbine blades coupled to the rotor. The vitrectomy probe includes a valve body interfacing with the rotor. During rotation of the air turbine, air is selectively routed to and from the actuator according to a rotational position of the rotor in relation to the valve body, thereby reciprocating the cutter.

Abstract: Multi-specific binding proteins that bind to and kill human cancer cells expressing epidermal growth factor receptor 2 (HER2 or ErbB2), but does not kill non-cancerous healthy human cells expressing HER2 are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of HER2 expressing cancer. The invention also relates to multi-specific binding proteins that trigger CD8+ T cell killing of tumor cells.

Abstract: Methods and systems are provided for an electric axle in a vehicle. An electric axle comprises an electric motor having a stator and a rotor, a coolant manifold mounted to an end plate of the rotor, wherein the coolant manifold is configured to flow coolant to rotor coolant lines extending axially through the rotor, and a first spray ring arranged adjacent to the coolant manifold and a second spray ring arranged distally to the coolant manifold, wherein the first spray ring receives coolant from the coolant manifold via an interior passage and the second spray ring receives coolant from the coolant manifold via an outer passage.

Abstract: The invention provides a generic operating system for coordinating, controlling and/or influencing the activities of a device. The invention is implemented using a blockchain platform with which the operating system is arranged to interact. The blockchain may be the Bitcoin blockchain. In a preferred embodiment, the device is an Internet of Things (TOT) device. The invention provides a computer-implemented control system and corresponding method for controlling a device, the system comprising a device configured for wireless communication with a network and having an IP address and a public-private key cryptographic key pair associated with the device; a software-implemented control component arranged to monitor the state of a blockchain network and/or transmit blockchain Transactions to the blockchain network; and a set of instructions arranged for execution by the control component to control the functionality of the device.

Abstract: A system, method, and computer-program product includes commencing a parent computer process based on receiving a request to perform an analytical operation on one or more datasets, commencing at least one child computer process that is launched by the parent computer process when the parent computer process initiates an execution of the analytical operation on the one or more datasets, transmitting, by the at least one child computer process, a request to the parent computer process to retrieve the one or more datasets, writing, by the parent computer process, the one or more datasets to a cross-process queue based on the parent computer process receiving the requests, reading, by the at least one child computer process, the one or more datasets from the cross-process queue, and executing, using an analytical application executing on the least one child computer process, the analytical operation based on the one or more datasets.

Abstract: An irrigated ablation electrode assembly comprises a distal member, a first manifold, and a second manifold. The distal member includes an outer surface; an inner surface; and at least one radially extending passageway that extends from the inner surface of the distal member to the outer surface of the distal member. The first manifold includes an outer surface, an inner cavity, and at least one radially extending passageway that extends from the inner cavity to the outer surface of the first manifold. The second manifold includes an outer surface, an inner surface, and at least one radially extending passageway that extends from the inner surface of the second manifold to the outer surface of the second manifold. Other irrigated ablation electrode assemblies are also presented.

Abstract: According to some embodiments, a longitudinal door system comprising one or more longitudinal doors for a railcar and a longitudinal operating beam coupled to the one or more longitudinal doors via one or more struts. A translation of the longitudinal operating beam is coupled to an opening and closing of the one or more longitudinal doors. The door system further comprising a gearbox coupled to the longitudinal operating beam and a first capstan receptacle. The gearbox is operable to translate a rotational movement of the first capstan receptacle to a linear movement of the longitudinal operating beam.

Abstract: A connector referred to herein as a knife plate, and the structural connections formed using the knife plate. The knife plate may have a first portion configured to affix to a first structural member, such as a vertical column. The knife plate may have a second portion configured to fit within a slot formed in a second structural member, such as a horizontal beam. The second structural member may be pinned to the knife plate using one or more dowels fit through the second structural member and the knife plate.

Abstract: The present disclosure relates to high dexterity robotic manipulation systems for ophthalmic microsurgical procedures. In certain embodiments, a robotic surgical system includes a master apparatus controllably coupled to a slave apparatus. The slave apparatus mounts to a patient's head and includes a dual tripod structure having two pluralities of linear actuator links pivotally supporting a surgical tool. The motions of the actuator links are controlled by direct drive actuators to provide at least 6-DOF for the surgical tool. A passive articulating arm having a SCARA mechanism and four-bar parallelogram mechanism attaches to the slave apparatus and counterbalances the weight thereof when mounted on a patient. The surgical system also includes sensors communicatively coupled to the slave apparatus and master apparatus to enable force feedback and force control.

Abstract: A method and system for generating adaptive explanations for associated recommendations is disclosed. The adaptive explanations comprise a syntactical structure and associated phrases that are selected in accordance with usage behaviors and/or inferences associated with usage behaviors. The phrases included in an adaptive explanation may be selected through application of a non-deterministic process. The adaptive explanations may be beneficially applied to recommendations that are associated with content, products, and people, including recommendations that comprise advertisements.