Abstract: A customizable multi-stage fluid treatment assembly typically includes a connector, a plurality of cartridges, and a cap. The plurality of cartridges have a treatment medium spaced within an interior volume of the individual cartridges, between the ends thereof. The ends of the plurality of cartridges are configured to receive a fluid, bring the fluid into operative contact with the treatment medium, and dispense the fluid from the opposing end of the cartridge. The connector is coupled with one end of the plurality of cartridges and has an inlet and an outlet for receiving and dispensing the fluid to and from an appliance. The cap is coupled with the other end of the plurality of cartridges, enclosing the fluid treatment assembly, which is configured to be received in a cavity of an appliance. The cartridges of the plurality of cartridges may be individually replaced with cartridges to meet customized needs.

Abstract: A breathing assistance unit for providing pressurized heated humidified air to a user is configured to increase user compliance. The breathing assistance unit comprises means for generating positive emotional and cognitive states of a user about the therapy.

Abstract: Systems and methods to identify candidates for targeted advertising in an online social gaming environment are disclosed. Example methods include generating a network graph representative of relationships between users associated with an online social gaming environment, the relationships based on connections between the users. Example methods also include collecting first social gaming data corresponding to participation by a first user and a second user in the online social gaming environment during a first period of time. The example methods further include calculating a first degree of influence of the first user of the online social gaming environment on the second user of the online social gaming environment, the first degree of influence based on the first social gaming data.

Abstract: The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: wherein the variables are as defined herein.

Abstract: The technology provides an optical system for converting a source of projected light to uniform light for a liquid crystal on silicon microdisplay in a confined space, such as in a near-eye display device. The optical system may include a first microlens array, a second microlens array, and a polarizer device disposed between the first microlens array and the second microlens array. The near-eye display device having first and second microlens arrays may be positioned by a support structure in a head-mounted display or head-up display.

Abstract: The present invention relates to a container for a beverage having an inner coating layer containing resveratrol, a process for preparing such a container, the use of said container for the storage of a beverage and the use of resveratrol as an additive to coating layers of such containers.

Abstract: The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: An elbow assembly for a mask assembly includes an anti-asphyxia valve (AAV) assembly that may take the form of a box-like frame work, a drop-in arrangement, or a slot-in arrangement. In each case, the AAV assembly may include a flap element which is movable so as to either direct ambient gas/air to the elbow assembly and thus the patient using the mask assembly, or to allow the passage of pressurized gas to the patient.

Abstract: In embodiments of eyebox adjustment for interpupillary distance, a first optical lens receives light of an image at a projected orientation of the light, and deviates the light by a deviation angle from the projected orientation of the light. A second optical lens receives the deviated light of the image from the first optical lens at the deviation angle, and alters the deviated light back to the projected orientation of the light for viewing the image. Left and right eyeboxes align with respective left and right eyes that view the image, and a distance between the left and right eyeboxes approximately correlates to an interpupillary distance between the left and right eyes. The light of the image can be laterally shifted to increase or decrease the distance between the left and right eyeboxes.

Abstract: A crystal puller for growing a crystal ingot includes a housing, insulation, a crucible assembly, a heat shield, and a dust barrier. The housing encloses a growth chamber, and has an upper wall with an inner surface and an aperture. The insulation separates an inside of the housing into an upper area and a lower area, and has a central opening. The crucible assembly is within the lower area to contain the melt. The heat shield is adjacent the central opening of the insulation, and forms a labyrinth gas path with the crucible assembly. The dust barrier extends from the inner surface of the upper wall to one of the insulation and the heat shield, and forms a seal with the upper wall around the aperture to inhibit particles from entering the growth chamber through the upper area of the housing.

Abstract: The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: The technology provides a waveguide display having a compact projection light engine and a diffractive waveguide. The diffractive waveguide includes input diffraction gratings with rolled k-vectors. The projection light engine provides collimating light to a projected exit pupil external to the diffractive waveguide. The projection light engine components may include a light (or illuminating) source, microdisplay, lenticular screen, doublet, polarizing beam splitter (PBS), clean-up polarizer, fold mirror, curved reflector and quarter waveplate. A method of manufacturing a diffractive waveguide includes providing input gratings with rolled k-vectors. Rays of light are diffracted by, and passed through, a master hologram to form input diffraction gratings of a copy substrate. A second copy substrate may likewise be formed with a different master hologram.

Abstract: A breathing arrangement for use between a patient and a structure to deliver a breathable gas to the patient includes a patient interface including a mouth covering assembly including a cushion structured to sealingly engage around an exterior of a patient's mouth in use, a nozzle assembly including a pair of nozzles structured to sealingly engage within nasal passages of a patient's nose in use without forming a seal on a nasal bridge region of a patient's face, each of the nozzles including a dual wall construction including an inner wall and an outer wall that surrounds the inner wall, and a flexible element connecting the mouth covering assembly and the nozzle assembly.

Abstract: The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length of 5 atoms extending between R1 and NR2R3 and a maximum chain length of 4 atoms extending between E and NR2R3, wherein one of the carbon atoms in the linker group may optionally be replaced by an oxygen or nitrogen atom; and wherein the carbon atoms of the linker group A may optionally bear one or more substituents selected from oxo, fluorine and hydroxy, provided that the hydroxy group when present is not located at a carbon atom ? with respect to the NR2R3 group and provided that the oxo group when present is located at a carbon atom ? with respect to the NR2R3 group; E is a monocyclic or bicyclic carbocyclic or heterocyclic group; R1 is an aryl or heteroaryl group; and R2, R3, R4 and R5 are as defined in the claims.

Abstract: Disclosed herein is a system and method for optimizing a developer's ability to find and navigate relevant documents, relationships, and other information related to an identifier in the code they are developing. An inline viewport is presented to the user in response to the user selecting an identifier in the code whereby the user is able to see relevant information related to the identifier in a spatially consistent location with the code they are investigating. Further, the developer has the ability to make changes to the code in the viewport without leaving the current editor.

Abstract: A beverage dispensing apparatus which includes a tank, a liquid inlet and a fluid dispensing system which includes a dispensing fluid conduit having a helical portion at least substantially vertically oriented within the interior volume of the tank. The beverage dispensing apparatus also includes a fluid circulating system that includes at least one fluid circulation conduit having an inlet portion positioned proximate the bottom portion of the tank and at least one outlet. A fluid cycling device is also included in the beverage dispensing apparatus and is configured to move fluid from the bottom portion of the tank to the fluid circulation conduit. The at least one outlet is configured to produce a fluid flow tangential to the orientation of the dispensing fluid conduit configuration. Evaporator coils extend around a perimeter of the tank's exterior sidewall surface and are configured to chill the fluid within the tank.

Abstract: The technology provides decoupling an aspheric optical element from a birdbath optical element in a near-eye display (NED) device. One or more aspheric lens are used with a spherical birdbath reflective mirror in a projection light engine of a NED device. A projection light engine provides image light (or other information), by way of the spherical birdbath reflective mirror and at least one aspheric lens, to a near-eye display of the NED device. The spherical birdbath reflective mirror collimates and reflects the image light to an exit pupil external to the projection light engine. Decoupling the aspheric optical element from the spherical birdbath reflective mirror may enable high modulation transfer function (MTF) and improved manufacturability of the projection light engine. The NED device having aspheric optical elements decoupled from a birdbath optical element may be positioned by a support structure in a head-mounted display (HMD) or head-up display (HUD).

Abstract: The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: Embodiments herein provide device isolation in a complimentary metal-oxide fin field effect transistor. Specifically, a semiconductor device is formed with a retrograde doped layer over a substrate to minimize a source to drain punch-through leakage. A set of high mobility channel fins is formed over the retrograde doped layer, each of the set of high mobility channel fins comprising a high mobility channel material (e.g., silicon or silicon-germanium). The retrograde doped layer may be formed using an in situ doping process or a counter dopant retrograde implant. The device may further include a carbon liner positioned between the retrograde doped layer and the set of high mobility channel fins to prevent carrier spill-out to the high mobility channel fins.

Abstract: An appliance that includes a cabinet having an exterior surface; a refrigeration compartment located within the cabinet; and a hydrophilic structure disposed on the exterior surface. The hydrophilic structure is configured to spread condensation. The appliance further includes a wicking structure located in proximity to the hydrophilic structure, and the wicking structure is configured to receive the condensation.