Abstract: The disclosure concerns a milking installation including milking positions configured to milk one animal at a time, a first common milk line connected to a first milk receiver, a second common milk line connected to a second milk receiver, a control arrangement, and at least one robot arm. Each milking position includes at least one teat cup and a flow directing arrangement, the flow directing arrangement including an inlet arrangement connected to the teat cup, a first outlet arrangement connected to the first milk line, and a second outlet arrangement connected to the second milk line. The control arrangement is configured to control the flow directing arrangement to fluidly connect the teat cup via the inlet arrangement with either the first outlet arrangement or the second outlet arrangement.

Abstract: A hearing device adapted for being worn at or in an ear of a user, comprises a) an input unit comprising at last two input transducers each for converting sound around said hearing device to an electric input signal representing said sound, thereby providing at least two electric input signals; b) a beamformer filter comprising a minimum processing beamformer defined by optimized beamformer weights, the beamformer filter being configured to provide a filtered signal in dependence of said at least two electric input signals and said optimized beamformer weights; c) a reference signal representing sound around said hearing device; d) a performance criterion for said minimum processing beamformer. The minimum processing beamformer is a beamformer that provides the filtered signal with as little modification as possible in terms of a selected distance measure compared to said reference signal, while still fulfilling said performance criterion.

Abstract: A monitoring system for a mobile liquid storage tank includes a plurality of independently operable sensor elements each configured to measure a liquid level inside the mobile liquid storage tank and a processor which iteratively receives a liquid level measurement from the sensor elements, determines a single liquid level output measurement that is robust to measurement variation by one or more of the plurality of independently operable sensor elements, and determines at least one liquid level usage analytic. A display is also provided which visually presents the at least one liquid level usage analytic.

Abstract: Liquid level detection systems and methods include a sensor having one or more radar transmitters, a plurality of radar receivers, and an antenna associated with each of the radar receivers at a respectively unique location relative to a liquid storage tank. A processor is configured to determine, based on radar returns from combinations of the one or more radar transmitters and the plurality of receivers, a single liquid level output for the storage tank in order to reduce an influence of possibly inaccurate radar returns due to localized effects from tank imperfections and/or solid/liquid buildup in the storage tank.

Abstract: Liquid level sensor systems and methods include a plurality of radar transmitter/receiver combinations each configured to provide a radar return from a respectively different location relative to the liquid storage tank. One or more processors are configured to determine, based on the respective radar returns from the plurality of radar transmitter/receiver combinations, a single liquid level output for the liquid storage tank in order to reduce an influence of possibly inaccurate radar returns due to localized effects from tank imperfections and/or solid/liquid buildup in the liquid storage tank.

Abstract: Liquid level sensor systems and methods include a sensor having a plurality of radar transmitters, one or more radar receivers, and antennas associated with each of the plurality of radar transmitters at respectively unique locations relative to the liquid storage tank. A processor is configured to determine, in view of the respective radar returns from combinations of the plurality of radar transmitters and one or more radar receivers, a single liquid level output for the liquid storage tank in order to reduce an influence of possibly inaccurate radar returns due to localized effects from tank imperfections and/or solid/liquid buildup.

Abstract: The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulations comprising said prodrug. It furthermore relates to their use as medicaments for the treatment of diseases which can be treated with growth hormone and to methods of treatment. It also relates to methods of application of such polymeric human growth hormone prodrug or pharmaceutical formulation.

Abstract: A hearing device comprises an input transducer comprising a microphone for providing an electric input signal representative of sound in the environment of the hearing device, a pre-processor for processing electric input signal and providing a multitude of feature vectors, each being representative of a time segment thereof, a neural network processor adapted to implement a neural network for implementing a detector configured to provide an output indicative of a characteristic property of the at least one electric input signal, the neural network being configured to receive said multitude of feature vectors as input vectors and to provide corresponding output vectors representative of said output of said detector in dependence of said input vectors.

Abstract: A coordinate measuring machine for measuring a number of measuring points on a surface, the coordinate measuring machine comprising a base, a probe head with an optical probe, a machine structure for linking the probe head to the base, at least one drive mechanism for providing movability of the probe head relative to the base, at least one encoding unit, an optical overview sensor unit arranged at the machine structure and a controlling and processing unit adapted at least for controlling the drive mechanism. The optical probe comprises an optical detection unit, in particular a sensor, a variable focal length lens capable of modifying its focal length and an actuating unit configured and arranged relative to the variable focal length lens so that the actuating unit provides setting and varying the focal length as a function of a controlling signal.

Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.

Abstract: The present invention is directed to compounds of formula IIa These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.

Abstract: A triangulation device for measuring a measurement object by a projection of a structured light pattern onto the measurement object. The triangulation device includes a projector projecting the structured light pattern decomposable into different spatial frequencies onto the measurement object. The projector comprises a matrix of pixel elements and a lens system which determines a wavefront with a wavefront aberration from a reference wavefront, and a camera including a lens system and an imaging sensor, the camera being configured to receive the structured light pattern projected by the projector onto the measurement object, and a processing unit configured to provide distance information by evaluating imaging information provided by the camera. The wavefront aberration comprises a primary spherical aberration coefficient Z9, wherein the primary spherical aberration coefficient Z9 is larger than 0.5?, wherein ? is a wavelength of the projected structured light pattern.

Abstract: A measuring system for measuring an object, the measuring system comprising a measuring device and a controlling and processing unit. The measuring device comprises at least one camera, a first optical sensor and a second optical sensor, the first optical sensor provides a first field of view and is configured for collecting first measuring data representing a first part of the object, the second optical sensor provides a second field of view and is configured for collecting second measuring data representing a second part of the object. The second optical sensor comprises at least three light sources configured for illuminating the object from at least three different poses. The controlling and processing unit comprises a second capturing mode.

Abstract: The present invention is directed to compounds of formula I The compounds are considered useful for the treatment of diseases associated with LRRK2 such as Parkinson's disease.

Abstract: A sensor device comprising a retro-reflecting element having a front boundary surface configured for entry of measuring light into the retro-reflecting element and a back boundary surface configured for reflecting a first part of the measuring light as reflected measuring light and configured for transmitting a second part of the measuring light as transmitted measuring light, wherein the front boundary surface and the back boundary surface are arranged on opposite sides of the retro-reflecting element, and a sensor unit configured and arranged so that the transmitted measuring light is detectable by the sensor unit. The front boundary surface and the back boundary surface are of curved shape.

Abstract: The present invention is directed to compounds of formula IIa These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.

Abstract: An optical detection unit comprising a retro-reflecting element which provides a reflection surface configured for retro-reflecting a first part of measuring light as reflected measuring light for providing determination of a position of the optical detection unit and a passage surface configured for transmitting a second part of the measuring light as transmitted measuring light, further comprising a sensor arrangement with a sensor configured and arranged behind of the retro-reflecting element so that the transmitted measuring light is detectable by the sensor. The optical detection unit comprises a referencing assembly with at least one illumination unit configured to emit reference illumination light. The at least one illumination unit is arranged with fixed positional relationship to the retro-reflecting element and/or the sensor arrangement and the referencing assembly is configured and arranged to direct the reference illumination light onto the sensor.

Abstract: A measuring device for acquiring a three-dimensional measuring point related to a target in a scene, the measuring device comprises a base unit, a support unit mounted on the base unit, a distance measuring unit comprising an emitting unit configured for emitting measuring radiation and a receiving unit configured for detecting at least a part of the measuring radiation reflected by the target and a directing unit mounted in the support unit configured for directing the measuring radiation towards the scene. The measuring device comprises a capturing unit, wherein the capturing unit is configured for capturing at least a scene image of at least part of the scene, the scene image is generated by the detection of visual-spectrum light, and a controlling and processing unit, wherein the controlling and processing unit is configured for aligning the directing unit.

Abstract: A measuring device for acquiring a three-dimensional measuring point related to a target in a scene, the measuring device comprises a distance measuring unit comprising an emitting unit configured for emitting collimated measuring radiation (T) and a receiving unit configured for detecting at least a part of the collimated measuring radiation reflected (R) by the target, a directing unit rotatable around an elevation axis and configured for directing the measuring radiation towards the scene, a capturing unit, wherein the capturing unit comprises an image sensor and is configured to capture at least a scene image of at least part of the scene, and a controlling and processing unit configured at least for aligning the directing unit.

Abstract: Disclosed herein are analogues of 6-(4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidin-1 -yl)-[1,2,4]triazolo[4,3-b]pyridazine of formula (Ib), which may be useful as positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.