Patents by Inventor Thomas Müller

Thomas Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OXATHIAZIN COMPOUNDS FOR INHIBITING GAPDH
    Publication number: 20220313702
    Abstract: A method of inhibiting GAPDH with certain oxathiazin-like compounds and/or related compounds.
    Type: Application
    Filed: May 21, 2020
    Publication date: October 6, 2022
    Applicant: Geistlich Pharma AG
    Inventors: Hanns Moehler, James C. Costin, Thomas Mueller
  • Method for monitoring, evaluating, and controlling a cyclic chromatographic purification process
    Patent number: 11460454
    Abstract: A method for monitoring, evaluating and controlling a cyclic chromatographic purification process that involves at least two adsorbers. According to the method, one step is monitoring of the chromatogram, including the measurement of at least one current concentration-proportional signal in the liquid. Another step is conducting an evaluation of the chromatogram, including a comparison of at least one of the current concentration-proportional signals measured in the monitoring step with a threshold value thereof. A further step is controlling the chromatographic purification process by adapting the termination of the currently running phase as a function of the comparison of the evaluation step and initiating the next phase. Finally, according to the method, the sequence of steps is carried out in given order at least twice.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: October 4, 2022
    Assignee: ChromaCon AG
    Inventors: Lars Aumann, Thomas Müller-Späth, Michael Bavand
  • SYSTEMS AND METHODS FOR TRAINING LANGUAGE MODELS TO REASON OVER TABLES
    Publication number: 20220309087
    Abstract: Systems and methods for pre-training and fine-tuning of neural-network-based language models to reason directly over tables without generating logical forms. In some examples, a language model can be pre-trained using masked-language modeling tasks synthetically generated from tables pulled from a knowledge corpus. In some examples, the language model may be further pre-trained using pairs of counterfactual statements generated from those tables, and/or one or more statements that compare selected data from those tables. The language model may then be fine-tuned using examples that include only a question, an answer, and a table, allowing fine-tuning examples to be harvested directly from existing benchmark datasets or synthetically generated.
    Type: Application
    Filed: March 29, 2021
    Publication date: September 29, 2022
    Inventors: Thomas Müller, Jonathan Herzig, Pawel Nowak, Julian Eisenschlos, Francesco Piccinno, Syrine Krichene
  • Mixer device
    Patent number: 11441461
    Abstract: A mixer device for an exhaust system of an internal combustion engine includes a tubular carrier (30) enclosing a mixer longitudinal axis (A) in a ring shape configuration and a mixer insert (28) carried at the carrier (30). The mixer insert (28) has a plurality of connection attachments (52, 54, 56) located at spaced locations from one another in relation to the mixer longitudinal axis (A) radially on the outside. The carrier (30) has a plurality of connection recesses (60, 62) for the permanent connection of the mixer insert (28) to the carrier (30).
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: September 13, 2022
    Assignee: Purem GmbH
    Inventors: Benjamin Röhr, Herve Tchamgoue, Frank Berkemer, Ruben Hass, Benjamin Deuscher, Thomas Müller
  • REAL-TIME NEURAL NETWORK RADIANCE CACHING FOR PATH TRACING
    Publication number: 20220284657
    Abstract: A real-time neural radiance caching technique for path-traced global illumination is implemented using a neural network for caching scattered radiance components of global illumination. The neural (network) radiance cache handles fully dynamic scenes, and makes no assumptions about the camera, lighting, geometry, and materials. In contrast with conventional caching, the data-driven approach sidesteps many difficulties of caching algorithms, such as locating, interpolating, and updating cache points. The neural radiance cache is trained via online learning during rendering. Advantages of the neural radiance cache are noise reduction and real-time performance. Importantly, the runtime overhead and memory footprint of the neural radiance cache are stable and independent of scene complexity.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 8, 2022
    Inventors: Thomas Müller, Fabrice Pierre Armand Rousselle, Jan Novák, Alexander Georg Keller
  • FULLY-FUSED NEURAL NETWORK EXECUTION
    Publication number: 20220284658
    Abstract: A fully-connected neural network may be configured for execution by a processor as a fully-fused neural network by limiting slow global memory accesses to reading and writing inputs to and outputs from the fully-connected neural network. The computational cost of fully-connected neural networks scale quadratically with its width, whereas its memory traffic scales linearly. Modern graphics processing units typically have much greater computational throughput compared with memory bandwidth, so that for narrow, fully-connected neural networks, the linear memory traffic is the bottleneck. The key to improving performance of the fully-connected neural network is to minimize traffic to slow “global” memory (off-chip memory and high-level caches) and to fully utilize fast on-chip memory (low-level caches, “shared” memory, and registers), which is achieved by the fully-fused approach.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 8, 2022
    Inventors: Thomas Müller, Nikolaus Binder, Fabrice Pierre Armand Rousselle, Jan Novák, Alexander Georg Keller
  • Methods of using c-Met modulators
    Patent number: 11433064
    Abstract: Methods of treating cancer by administering a compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments are described, wherein R1 is halo; R2 is halo; and Q is CH or N.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: September 6, 2022
    Assignee: Exelixis, Inc.
    Inventors: Dana T. Aftab, Thomas Mueller, Aaron Weitzman, Jaymes Holland
  • SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE
    Publication number: 20220259228
    Abstract: The present application relates to novel (imidazo[1,2-a]pyridin-3-yl)methyl-substituted diazaheterobicyclic compounds, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory disorders including sleep-related respiratory disorders such as obstructive sleep apnoea and central sleep apnoea and snoring. The present application further relates to a method of discovering a compound having TASK-1- and/or TASK-3-blocking properties.
    Type: Application
    Filed: September 15, 2021
    Publication date: August 18, 2022
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Martina DELBECK, Michael Hahn, Thomas Müller, Klemens Lustig, Johanna Anlahr, Udo Albus, Doris Gehring, Björn Rosenstein, Karl Collins, Niels Lindner, Janine Nicolai, Moritz Beck-Broichsitter
  • MEDIA-RESISTANT PRESSURE SENSOR FOR LARGE PRESSURE RANGES
    Publication number: 20220244122
    Abstract: A pressure sensor comprises a housing, a flexible membrane which, together with the housing, forms a hermetically closed cavity, a sensor element arranged in the cavity, and a gaseous medium in the cavity.
    Type: Application
    Filed: January 10, 2022
    Publication date: August 4, 2022
    Inventors: Rainer Markus SCHALLER, Thomas MUELLER, Bernhard WINKLER
  • 1-PHENYL-5-AZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR USE FOR CONTROLLING UNWANTED PLANT GROWTH
    Publication number: 20220235036
    Abstract: What are described are compounds of the general formula (I) and agrochemically acceptable salts thereof and their preparation and their use in the crop protection sector.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 28, 2022
    Inventors: Michael Gerhard HOFFMANN, Estella BUSCATO ARSEQUELL, Harald JAKOBI, Thomas MUELLER, Erin Nicole SMITH, Elisabeth ASMUS, Anu Bheemaiah MACHETTIRA, Elmar GATZWEILER, Christopher Hugh ROSINGER, Dirk SCHMUTZLER
  • METHOD AND MOUNTING FRAME FOR MANUFACTURING A VAPORIZER UNIT FOR AN INHALER
    Publication number: 20220225686
    Abstract: A method for manufacturing a vaporizer assembly for an inhaler comprises the steps of providing a plurality of connection stations and performing at least one assembly step at each connection station to produce a vaporizer assembly at each connection station.
    Type: Application
    Filed: June 16, 2020
    Publication date: July 21, 2022
    Inventors: NIKLAS ROMMING, LASSE CORNILS, JAN JAKLIN, THOMAS MÜLLER
  • Fiber cement material formulations and compositions thereof
    Patent number: 11370708
    Abstract: A fiber cement material formulation comprising a cementitious binder, a siliceous material, fiber, alumina trihydrate and a bifunctional low density additive wherein the bifunctional low density additive comprises any one or more of diatomaceous earth, recycled autoclave fiber cement dust or cellulose dust. The fiber cement material formulation optionally further comprises a secondary low density additive which may be perlite. In some embodiments, a fiber cement article manufactured from the fiber cement material formulation comprises a density of approximately 1.1 g/cm3 or below.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: June 28, 2022
    Assignee: James Hardie Technology Limited
    Inventors: Xiangyuan Liu, Huagang Zhang, Jongmin Keum, Yongjun Chen, Yan Li, Weiling Peng, Thinh Pham, Farshad J. Motamedi, Lijun Mao, Thomas Mueller
  • SYSTEMS AND METHODS USING GENERIC DATABASE SEARCH MODELS
    Publication number: 20220188284
    Abstract: A computer system includes one or more database search models configured to search data contained in a plurality of database tables. The one or more database search models can include a plurality of structural containers and one or more search enabling containers. The plurality of structural containers can represent objects having a structural relationship and contain property data of the objects. The property data of the objects can be obtained from the plurality of database tables. The plurality of structural containers can be shared by the one or more database search models. The one or more search enabling containers can correspond to the one or more database search models and specify a scope for searching data and a format for presenting search results.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 16, 2022
    Applicant: SAP SE
    Inventor: Thomas Mueller
  • IMPROVEMENTS IN OR RELATING TO A METHOD OF SEPARATING AND ANALYSING A COMPONENT
    Publication number: 20220187242
    Abstract: A method of separating and analysing a plurality of components in a heterogeneous sample is provided. The method comprising the steps of: introducing a separation fluid into a separation channel that is elongate in a first direction; introducing the heterogeneous sample into said channel; separating, in the first direction, the components in the sample; introducing an auxiliary fluid into said channel; creating a lateral distribution of the components in a second direction substantially perpendicular to the first direction; and determining, sequentially, a property of each of the components based on the regimen by which the lateral distribution was created. An apparatus for separating and analysing a plurality of components in a heterogeneous sample is also provided.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 16, 2022
    Applicant: Fluidic Analytics Limited
    Inventors: Thomas Mueller, Philipp Hahn, Sean Devenish, Ashish Asthana, Tuomas Pertti Jonathan Knowles
  • EVAPORATOR DEVICE FOR AN INHALER, CONSUMPTION UNIT, INHALER, AND PRODUCTION METHOD
    Publication number: 20220151295
    Abstract: A vaporizer device for an inhaler comprises at least one electric vaporizer for vaporizing liquid fed to the vaporizer, wherein the liquid is transported by capillary forces from an inlet side through at least one liquid channel to an outlet side, where vaporized liquid can be added to an air stream, a carrier retaining the vaporizer, and at least one electrical line electrically contacting the vaporizer. The electrical line comprises a planar contact area, and the vaporizer and the planar contact area of the electrical line are materially and electrically conductively bonded to each other.
    Type: Application
    Filed: February 14, 2020
    Publication date: May 19, 2022
    Inventors: LASSE CORNILS, NIKLAS ROMMING, JAN JAKLIN, GUNNAR NIEBUHR, TIM ULLNER, THOMAS MUELLER
  • CONSUMPTION UNIT, INHALER AND MANUFACTURING METHOD
    Publication number: 20220134026
    Abstract: A consumption unit for an inhaler comprises a liquid reservoir, a vaporizer device arranged in the liquid reservoir, and a vent having a flow channel extending in the liquid reservoir to a flow connection of the flow channel to the environment. The liquid reservoir comprises a filling opening, which is closed by means of a first closure part.
    Type: Application
    Filed: February 13, 2020
    Publication date: May 5, 2022
    Inventors: GUNNAR NIEBUHR, LENNART KOCK, THOMAS MÜLLER, BENJAMIN JUNG, VOLKMAR VOIGTLÄNDER, MARKUS SCHMIDT, MATTHIAS GIESE, MICHAEL KLEINE WÄCHTER, MARC KESSLER
  • 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH
    Publication number: 20220135536
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and prophylaxis of diseases, in particular hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: August 20, 2021
    Publication date: May 5, 2022
    Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MÜLLER, Sherif El SHEIKH, David B. SYKES, Steven James FERRARA, Michael KRÖBER, Claudia MERZ, Michael NIEHUES, Martina SCHÄFER, Katja ZIMMERMANN, Carl Friedrich NISING
  • Use of a Communication Profile by a Plurality of Mobile Terminals
    Publication number: 20220141649
    Abstract: A mobile terminal includes a communication device to communicate with an external entity, a storage device to store an identifier, and a processing device. The processing device activates a communication profile, transmits a notification relating to the activation to an external entity, and stores an identifier of the activation in the storage device. The processing device further receives a deactivation request and an identifier from the external entity and deactivates the communication profile if the received identifier corresponds to the stored identifier. The identifier can be determined by the mobile terminal and transmitted from the mobile terminal to the external entity. The identifier can also be determined by the external entity and transmitted to the mobile terminal.
    Type: Application
    Filed: February 5, 2020
    Publication date: May 5, 2022
    Inventors: Thomas MUELLER, Michael NEUHAEUSER
  • DRIVER ASSISTANCE SYSTEM AND METHOD FOR AN ASSISTED OPERATION OF A MOTOR VEHICLE
    Publication number: 20220118993
    Abstract: The invention relates to a driver assistance system for a motor vehicle, comprising a surroundings sensor system, a controller, and an analysis module. The controller is equipped and designed so as to ascertain an assistance function control signal on the basis of surroundings data detected by the surroundings sensor system, said assistance function control signal being in a specified functional relationship with at least one assistance system parameter and the detected surroundings data, and to actuate the vehicle so as to provide an assistance function by means of the assistance function control signal. The analysis module is equipped and designed so as to ascertain a success value for the assistance function control signal using reference information and to initiate an optimization of the at least one assistance system parameter if the success value falls below a success threshold.
    Type: Application
    Filed: December 4, 2019
    Publication date: April 21, 2022
    Inventors: GEORG SCHNEIDER, THOMAS MUELLER
  • Stackable chair
    Patent number: D961952
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: August 30, 2022
    Assignee: VS Vereinigte Spezialmoebelfabriken GmbH & Co. KG
    Inventors: Martin Ballendat, Walter Richter, Jens Heller, Thomas Mueller