Abstract: A system includes a matrix transpose component, a matrix processing component, a data modification component, and a data reduction component. The matrix transpose component is configured to transpose a stored matrix to an output matrix. The matrix processing component is configured to multiply the output matrix with a mask vector to determine a result vector. The data modification component is configured to modify at least a portion of the result vector to determine a modified vector. The data reduction component is configured to sum at least a portion of elements included in the modified vector.

Abstract: An interface assembly comprises a nasal mask that includes a seal having a rolling portion. The rolling portion of the seal rolls over a portion of a clip that secures the seal to a frame. The frame has a ball and socket connection to a connector. The connector comprises an elbow having integrally formed exhaust holes and a swivel.

Abstract: A patient interface can have a frame supporting a sealing member. Various features of the sealing member can improve comfort and sealing performance in the context of forming seals with the nares of a user, as well as contact with other facial surfaces. The sealing member can include convex portions, concave portions and thickness variations for providing various sealing, comfort, and deformability effects.

Abstract: An attachment for a haircare appliance, the attachment including an air inlet, an air outlet for emitting the airflow. The attachment has a curved surface adjacent to and downstream of the air outlet, and a flat surface adjacent to and extending rearwardly from the air outlet. A haircare appliance having an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet. The haircare appliance has a curved surface adjacent to and downstream of the air outlet, and a flat surface adjacent to and extending rearwardly from the air outlet.

Abstract: A haircare appliance having an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet and an attachment for a haircare appliance, the attachment including an air inlet, an air outlet. A curved surface adjacent to and downstream of the air outlet. The haircare appliance or the attachment has a curved surface adjacent to and downstream of the air outlet. The haircare appliance or the attachment is configured such that airflow exiting the air outlet generates a first force to attract hair toward the curved surface, and a second force to push hair away from the curved surface.

Abstract: An oxygen scavenging dressing includes a patient interface layer, an absorbent layer, a foam layer, an oxygen scavenging layer, and a film layer. The film layer is configured to seal with a patient's skin and define an inner volume within which the patient interface layer, the absorbent layer, the foam layer, and the oxygen scavenging layer are positioned.

Abstract: A polymer comprising a repeating structure of formula (I) wherein Ar in each occurrence is an arylene or heteroarylene group; p is at least 2; one of Y1 and Y2 is CR1 wherein R1 is H or a substituent; and the other of Y1 and Y2 is N. The polymer may be formed by reaction of monomers containing reactive groups which react to form an imine. The polymer may be used as a thermally conductive polymer, e.g. a thermally conductive layer of an electronic device.

Abstract: An arrangement for a drug delivery device includes a housing with a proximal end and a distal end, a needle shield remover configured to be rotationally locked to a needle shield covering a needle, and a guiding interface. The needle shield remover is releasably connectable to the housing. The guiding interface is configured such that, when the needle shield remover rotates with respect to the housing from a state in which the needle shield remover is connected to the housing, the guiding interface guides a movement of the needle shield remover relative to the housing in a direction away from the proximal end of the housing to disconnect the needle shield remover from the housing. Movement of the needle shield remover relative to the housing to disconnect the needle shield remover includes an axial movement and a rotational movement of the needle shield remover relative to the housing.

Abstract: The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.

Abstract: The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in patients with insufficient glycemic control despite a therapy with an oral and/or a non-oral antidiabetic drug.

Abstract: According to one aspect, embodiments herein provide a furnace for debinding and sintering additively manufactured parts comprising a unitarily formed retort having at least one open side, a heater for heating a sintering volume within the retort to a debinding temperature and to a sintering temperature, an end cap sealing the at least one open side, a forming gas line penetrating the end cap for supplying forming gas at a flowrate, and a heat exchanger within the retort, outside the sintering volume, and adjacent a heated wall of the retort, the heat exchanger having an inlet connected to the forming gas line and an outlet to the sintering volume, wherein the heat exchanger includes a heat exchange tube length sufficient to heat the forming gas to within 20 degrees Celsius of the sintering temperature before the forming gas exits the outlet.

Abstract: The invention relates to an autoinjector comprising a housing (125) which is configured to receive a reservoir (120) with a fluid, a pump arrangement (100), which is configured to drive the fluid from the reservoir (120) towards and through an outlet (180) of the autoinjector in a dispensing operation.

Abstract: The invention relates to an autoinjector comprising —a housing (105) which is configured to receive an operating reservoir (120, 220) with a fluid, —a pump arrangement (100, 200), which is configured to drive the fluid from the operating reservoir (120, 220) towards and through an outlet (180) of the autoinjector in a dispensing operation.

Abstract: The invention relates to an autoinjector (100) comprising —a housing (170) which is gas-tight to the outside, —a fluid reservoir (110) with a fluid, wherein the fluid reservoir (110) comprises a flexible material, —a container (140) which comprises at least a first section which is configured to contain a first substance which comprises gas or which can be converted into gas, wherein ?the container (140) is configured to assume two different states, ?a first state in which the first section is sealed so that the at least first substance is contained in the first section, ?a second state in which the at least first substance is released from the first section into the housing (170) causing an increase of gas pressure within the housing (170) which acts on the fluid reservoir (110) causing the fluid inside the fluid reservoir (110) to move through the fluid reservoir (110) towards and through an outlet (230) of the autoinjector (100).

Abstract: A diffuser element for use over a vent opening of a breathing assistance apparatus. In some configurations, the diffuser element is formed by knitting or weaving one or more threads together into an interlocking pattern. In some configurations, the diffuser pad has a first surface and an opposing second surface and at least the first surface includes a surface texture. Arrangements for coupling the diffuser element to a structure that defines or carries the vent are also disclosed.

Abstract: A drug delivery device includes a housing element, a release member, a plunger rod, a transfer member arranged rotatably with respect to the housing element, an energy member, a displaceable element being displaceable between a first position and a second position, wherein the transfer member and the plunger rod are operatively coupled such that a rotation of the transfer member is converted into an axial movement of the plunger rod, the drug delivery device has a first locked state, wherein, in the first locked state, (i) a releasable first locking mechanism prevents a rotational movement of the transfer member, (ii) the release member is in an initial position and arranged to hold the displaceable element in the first position, and (iii) the transfer member is coupled to the displaceable element held in the first position via an axial-lock interface which prevents an axial movement of the transfer member.

Abstract: A drug delivery device includes a housing element, a release member, a plunger rod, an energy member, and a displaceable element. The drug delivery device has a first locked state in which the release member is in a distal position and arranged to hold the displaceable element in a first radial position to prevent a movement of the plunger rod in distal direction by the energy member. The drug delivery device is configured to be switched from the first locked state into a released state by moving the release member from the distal position into a proximal position. In the released state, the release member no longer holds the displaceable element in the first radial position, which enables a movement of the displaceable element from the first radial position into a second radial position to release the plunger rod such that the plunger rod moves in the distal direction.

Abstract: A drug delivery device includes a housing element, a protection member, a moveable member, a first stop feature, a second stop feature configured to interact with the first stop feature, wherein the drug delivery device is configured to perform a drug delivery operation, wherein the drug delivery device is configured to be switchable from an initial state into a released state, wherein in the released state (i) the protection member is in a proximal position, and (ii) the moveable member moves into a locking position, and wherein the drug delivery device is configured to be switchable from the released state into a post-released state by moving the protection member from the proximal position in a distal direction into a post-release position, wherein in the post-released state (i) the protection member is in the post-release position and (ii) the moveable member is in the locking position.

Abstract: A drug delivery device includes a housing element, a protection member, a movable member, wherein the drug delivery device has an initial state, in which (i) the protection member is in an extended position to cover the drug delivery element, (ii) the protection member is movable in a proximal direction from the extended position into a retracted position in order to expose the drug delivery element, and (iii) the protection member is coupled to the movable member in distal direction and proximal direction such that an axial movement of the protection member in both, the distal and proximal direction, results in an axial movement of the movable member in the same direction. The drug delivery device is configured such that, starting from the initial state, movement of the protection member in proximal direction initiates a rotation of the movable member relative to the protection member by a predetermined angle.