Abstract: The present invention is to provide a method for producing duplex stainless steel seamless pipe in which a duplex stainless steel billet can be inhibited from generating an oxide scale on the surface thereof during heating and the generation of outer surface flaw can also be prevented. The billet is heated in the a heating furnace for 1.5 hours or more and 4.0 hours or less at a heating temperature of 1250° C. or more and 1320° C. or less while regulating the average concentration of sulfur dioxide (SO2) gas in the atmosphere within the furnace to 0.01 volume % or less.

Abstract: A method for manufacturing an Ni base alloy pipe stock comprises piercing and rolling a billet by use of Mannesmann piercing and rolling mill. The pipe stock has controlled amounts of C, Si, Mn, P, S, Cr, Ni, Mo, W, Cu, Al, N, with the balance being Fe. With the method, the following equations are satisfied, wherein values of TGBm, Psr and P? represented by the following equations (1) to (3) being not more than 1300, not more than 200 and not less than 0, respectively TGBm=1380?5000P?100S?4400C ??(1), PsrNi+10(Mo+0.5W)+100N ??(2), P?=(Ni?50)+10(N?0.1)?2(Cr?25)?5(Mo+0.5W?6)+12 ??(3), wherein each element symbol in the equations represents mass % of the element concerned.

Abstract: By using a piercing mill that includes a pusher on the entrance side, a plug on the exit side along a pass line, and a plurality of angled rolls as being provided around the plug so as face to each other, in the case where the maximum diameter of an unsound region consisting of center segregation and porosity in a cross section of a billet is d [mm], piercing-rolling is performed under the condition that the plug nose rolling reduction ratio (TDF) expressed by Formula (1) satisfies Formula (2). TDF=(Bd?D1)/Bd??(1) TDF??0.50×(d/Bd)+0.06??(6) In Formulae (1) and (2), Bd is the billet diameter [mm], and D1 is the opening [mm] between the angled rolls at the plug nose position. Thereby, when piercing-rolling is performed, the occurrence of an inner surface flaw attributable to the center segregation and porosity in the billet can be prevented reliably.

Abstract: A plug includes a front edge portion having a convex curvature; a cylindrical portion having a truly or nearly cylindrical shape; a trunk portion having an outer diameter gradually increasing toward a rear edge thereof; a mandrel joint provided in a rear edge portion of the plug; a lubricant ejection hole running through the trunk portion from the mandrel joint that opens on the surface of the cylindrical portion; and a coating comprising oxides and Fe that is formed on the base metal surface of each of the front edge portion as well as the trunk portion by arc spraying using an iron wire. In this way, the plug can prevent inner surface flaws from occurring in a hollow blank that is deformed by piercing-rolling, and can extend its life without requiring a long time for making it.

Abstract: A compound represented by the following general formula (II) or a salt thereof is used as an activator of PPAR?. wherein Ga is O, CH2 or the like; Aa is thiazole, oxazole, or thiophene, which can have a substituent such as C1-8 alkyl, C1-8 alkoxy, halogen, C1-8 alkyl substituted with halogen or the like; Ba is a C1-8 alkylene or C2-8 alkenylene chain; and each of R1a and R2a independently is hydrogen, C1-8 alkyl, C1-8 alkoxy, halogen, C1-8 alkyl substituted with halogen or the like.

Abstract: There is provided an antioxidant agent excellent in anti-dripping property and anti-peeling property. The antioxidant agent in accordance with the present invention contains a plurality of glass frits having different softening points, potter's clay, and bentonite and/or sepiolite. On account of the potter's clay, the antioxidant agent applied to the surface of a metallic starting material is less liable to drip down. Further, on account of the bentonite and/or sepiolite, the antioxidant agent is less liable to peel off the surface of the metallic starting material.

Abstract: Provided is a method for producing a seamless tube, in which after a starting material to be extruded has been heated to a heating temperature T [° C.] satisfying the relationship of Formula (1) or Formula (2) depending on the outside diameter d0 [mm] thereof, the starting material is hot extruded by providing a solid lubricating glass between the starting material to be extruded and a die, whereby a transverse flaw on the outer surface in the top portion of tube can be prevented when hot extrusion is performed by using a starting material for extrusion having low deformability at high temperatures. When d0<200, T?1250+1.1487×A?7.838×ln(t0/t)?10.135×ln(d0/d) . . . (1); when d0?200, T?1219+1.1487×A?7.838×ln(t0/t)?10.135×ln(d0/d) . . . (2), where A=L/Vav×1000 [msec.].

Abstract: There is provided an antioxidant agent capable of preventing scale from being produced on the surface of a heated metallic starting material more effectively than the conventional antioxidant agent. The antioxidant agent according to the present invention contains a plurality of glass frits having different softening points and an inorganic compound having a melting point not higher than 600° C. The inorganic compound mainly softens in the low-temperature range of about 600° C. The plurality of glass frits mainly soften in the low-temperature range of about 600 to 1300° C. Therefore, the antioxidant agent covers the surface of metallic starting material in a broad temperature range, oxidizes the surface of metallic starting material, and prevents the production of scale.

Abstract: A compound represented by the following general formula (II) or a salt thereof is used as an activator of PPAR?. wherein Ga is O, CH2 or the like; Aa is thiazole, oxazole, or thiophene, which can have a substituent such as C1-8 alkyl, C1-8 alkoxy, halogen, C1-8 alkyl substituted with halogen or the like; Ba is a C1-8 alkylene or C2-8 alkenylene chain; and each of R1a and R2a independently is hydrogen, C1-8 alkyl, C1-8 alkoxy, halogen, C1-8 alkyl substituted with halogen or the like.

Abstract: A plug 2 used for a piercer according to the invention includes a tip end portion 23, a cylindrical portion 24, a barrel portion 25, a mandrel coupling portion 22, and an injection hole 21. The injection hole 21 penetrates from the surface of the cylindrical portion 24 to the surface of the mandrel coupling portion 22 and an externally supplied lubricant is injected from the hole. A clearance forms between the pierced material and the cylindrical portion 24. The injection hole 21 is formed at the cylindrical portion 24, and therefore the material in the process of piercing does not contact the injection hole 21. Therefore, an inner surface defect attributable to the contact between the material and the injection hole 21 can be prevented from being generated.

Abstract: When a hollow billet is inserted into a container, and hot expanding piercing is downwardly performed by using a plug, hot piercing is performed by using a formed glass complex comprising a ring-shaped formed glass part and a ring-shaped projecting part. The ring-shaped formed glass part assumes a disc shape having a circular opening for allowing a plug to be inserted at the center thereof. The ring-shaped projecting part is attached to the opening of the ring-shaped formed glass part, and assumes a ring shape projecting perpendicularly to the ring-shaped formed glass part. Thereby, the piercing work can be done safely, and defects can be prevented from occurring on the inner surface of the billet.

Abstract: A method for straightening a tube by using an asymmetric roll, which has different diameters D1 (exit side), D2 (entry side) at relative maximum diameter portions, left and right roll shoulder portions, as a straightening roll of a straightener, wherein the roll shoulder having a smaller diameter is disposed to be located on the tube entry side. The straightening roll used therefor comprises roll shoulders 3a and 3b and a roll barrel portion 4, in which D1>D2 and 0.004?(D1?D2)/d?0.2 (d: outer diameter of tube to be straightened) are satisfied. Further, an aspect of the invention may define radii of curvatures of entry-side and exit-side shoulder potions in a section of the roll cut along a plane including the roll central axis, or a curve representing an outer surface of the roll barrel portion.

Abstract: An agent comprising, as an active ingredient, a xanthine oxidase inhibitor such as 2-[3-cyano-4-(4-fluorophenoxy)phenyl]-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-[3-cyano-4-(4-fluorophenoxy)phenyl]thiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-(3-cyano-4-phenoxyphenyl)thiazolo[5,4-d]pyrimidine, TMX-67, and FYX-051, which can be used as an agent for overcoming anti-cancer agent resistance.

Abstract: A plug includes a front edge portion having a convex curvature; a cylindrical portion having a truly or nearly cylindrical shape; a trunk portion having an outer diameter gradually increasing toward a rear edge thereof; a mandrel joint provided in a rear edge portion of the plug; a lubricant ejection hole running through the trunk portion from the mandrel joint that opens on the surface of the cylindrical portion; and a coating comprising oxides and Fe that is formed on the base metal surface of each of the front edge portion as well as the trunk portion by arc spraying using an iron wire. In this way, the plug can prevent inner surface flaws from occurring in a hollow blank that is deformed by piercing-rolling, and can extend its life without requiring a long time for making it.

Abstract: A starting material to be extruded made of a high alloy comprising, in mass %, Cr: 20 to 30% and Ni: more than 22% and 60% or less is heated to a temperature predetermined according to the contents of Mo and W and is subjected to a hot-extrusion process, the heating temperature T (° C.) satisfying a relationship of Formula (1), (2), or (3), which is expressed in terms of the average cross-sectional area A (mm2) of the starting material to be extruded, the extrusion ratio EL (?), and the extrusion speed V (mm/s). As a result, a high-alloy seamless tube can be produced without generating cracking and/or seam flaws. When 0%?Mo+0.5W<4%: T?1343?0.001322×A?1.059×EL?0.129×V??(1) When 4%?Mo+0.5W<7%: T?1316?0.001322×A?1.059×EL?0.129×V??(2) When 7%?Mo+0.5W: T?1289?0.001322×A?1.059×EL?0.

Abstract: A compound having the following formula (II) or its pharmacologically acceptable salt is used as a P2X4 receptor antagonist: in which R11 represents hydrogen or an alkyl group having 1-8 carbon atoms; R21 represents an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkyl group having 1-8 carbon atoms and having 1-3 halogen substituents, or hydroxyl; and R31 is hydrogen or a halogen atom.

Abstract: The invention relates to purification of (2S,3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid [hereinafter, referred to as the carboxylic acid] using the salt of the carboxylic acid with an organic amine selected from the group consisting of piperazine, adamantane amines and others. The invention also relates to providing crystalline sodium salt of the carboxylic acid. The sodium salt is usable as a material for preparing medicaments and improved in storage stability, and has the following characteristics: DSC: exothermic peak observed at a temperature in the range of 170 to 175° C. with weight decrease; and characteristic absorption bands of infrared absorption spectrum (KBr tablet): 3255, 2950, 2860, 1670, 1630, 1550, 1460, 1435, 1395, 1365, 1310, 1260, 1110, 890 cm?1.

Abstract: Provided is a method for producing a seamless tube, in which after a starting material to be extruded has been heated to a heating temperature T [° C.] satisfying the relationship of Formula (1) or Formula (2) depending on the outside diameter d0 [mm] thereof, the starting material is hot extruded by providing a solid lubricating glass between the starting material to be extruded and a die, whereby a transverse flaw on the outer surface in the top portion of tube can be prevented when hot extrusion is performed by using a starting material for extrusion having low deformability at high temperatures. When d0<200, T?1250+1.1487×A?7.838×ln(t0/t)?10.135×ln(d0/d) . . . (1); when d0?200, T?1219+1.1487×A?7.838×ln(t0/t)?10.135×ln(d0/d) . . . (2), where A=L/Vav×1000 [insect.

Abstract: A piercing mill includes a plurality of inclined rolls, a plug, a pusher, and an undriven guide roll. The pusher pushes a round billet from the rear end at least until the round billet advances for a prescribed distance after contacting the inclined rolls. The guide roll is between the inclined rolls and the pusher and includes a roll shaft and a roll surface, with the roll shaft arranged obliquely with respect to a pass line PL. The sectional shape of the roll surface is a concave arch shape. The round billet is rotated by the guide roll and the friction force generated when the round billet contacts the inclined rolls is reduced. Consequently, the wear of the inclined rolls can be restrained if the round billet is pierced and rolled while it is pushed in between the inclined rolls using the pusher.

Abstract: An agent comprising, as an active ingredient, a xanthine oxidase inhibitor such as 2-[3-cyano-4-(4-fluorophenoxy)phenyl]-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-[3-cyano-4-(4-fluorophenoxy)phenyl]thiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-(3-cyano-4-phenoxyphenyl)thiazolo[5,4-d]pyrimidine, TMX-67, and FYX-051, which can be used as an agent for overcoming anti-cancer agent resistance.