Abstract: The present invention relates to a nucleic acid construct comprising a UTR and use thereof. Specifically, the UTR can significantly improve the expression efficiency of a target gene in the nucleic acid construct. The nucleic acid construct may comprise a nucleic acid sequence expressing, for example, a human hepatocyte growth factor (hHGF), and can be used in a gene therapy for serious lower limb ischemia, diabetic foot, and other diseases.

Abstract: The present disclosure provides a VEGF-binding molecule and a pharmaceutical use thereof. In particular, the present disclosure relates to a VEGF-binding molecule, a nucleic acid encoding the VEGF-binding molecule, a vector comprising the nucleic acid, and a pharmaceutical use.

Abstract: Provided are an aromatic L-amino acid decarboxylase (AADC)/glial cell line-derived neurotrophic factor (GDNF) polynucleotide, and a use thereof in treating Parkinson's disease. Specifically, provided are a method for and a use in treating neurodegenerative diseases (such as Parkinson's disease) by delivering AADC and a GDNF to specific areas of the brain by a gene delivery system using AAV as a vector.

Abstract: Disclosed are a V-N microalloyed steel and a method for producing a V-N microalloyed and surface-crack-free continuous casting blank. The V-N microalloyed steel is composed of the following chemical components by mass percentage: 0.09%-0.13% of C, 0.1%-0.4% of Si, 1.0%-3.0% of Mn, less than or equal to 0.05% of P, less than or equal to 0.05% of S, 0.1%-0.4% of V, 0.011%-0.2% of N and the balance of Fe and unavoidable impurity elements. A continuous casting blank is subjected to component control according to the chemical components of the V-N microalloyed steel; and the production method therefor comprises converter smelting, LF refining and continuous casting steps in sequence.

Abstract: Provided are a recombinant adeno-associated virus (rAAV) having a variant capsid, and an application thereof. Specifically, provided are a variant AAV capsid protein, an rAAV viral particle comprising the variant AAV capsid protein, and an application thereof in delivering a gene product to a cell (e.g., a retinal cell).

Abstract: A backlight and a display device are provided herein, which is related to the field of display technology and intends to improve visual effect of the image displayed by the display device. The backlight may include a back plate, a light guide plate and a light source. The back plate includes an accommodation groove, and the light guide plate includes a holding groove at a first side surface of the light guide plate. The light source includes at least one light emitting element. The holding groove is configured to hold at least a portion of the at least one light emitting element, and the accommodation groove is configured to accommodate the light guide plate and the light source.

Abstract: An ultra-high phosphorus molten iron low-cost smelting method for polar steel includes successively deoxidizing and tapping alloying raw materials including molten iron; performing slag adjusting and refining on the molten steel obtained in the converter smelting step to obtain a refined molten steel; vacuum degassing the refined molten steel; and performing continuous casting on the molten steel obtained after the RH degassing step to obtain a cast billet.

Abstract: A steel board for polar marine engineering and a preparation method therefor. According to weight percentage, the components of the steel board are: C: 0.06-0.09%, Si: 0.20-0.35%, Mn: 1.48-1.63%, Nb: 0.020%-0.035%, Ti: 0.010%-0.020%, V: 0.020%-0.035%, Ni: 0.08%-0.17%, Als: 0.015%-0.040%, P: ?0.013% and S: ?0.005%. The preparation method for the steel board comprises: pre-refining, refining and casting to obtain a cast billet, and the slowly cooling down same. The slowly cooled billet is heated and then rolled out to obtain the steel board; and the steel board is cooled down and ready. The steel has an excellent comprehensive performance in terms of having high strength and low temperature resistance, being easy to weld and corrosion proof, and the steel has good low-temperature aging impact toughness.

Abstract: A backlight and a display device are provided herein, which is related to the field of display technology and intends to improve visual effect of the image displayed by the display device. The backlight may include a back plate, a light guide plate and a light source. The back plate includes an accommodation groove, and the light guide plate includes a holding groove at a first side surface of the light guide plate. The light source includes at least one light emitting element. The holding groove is configured to hold at least a portion of the at least one light emitting element, and the accommodation groove is configured to accommodate the light guide plate and the light source.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.

Abstract: In one aspect the present subject matter is directed to a system for cooling a turbine engine. The system includes a cooling medium source, a stator vane having an internal flow passage that is in fluid communication with the cooling medium source and a turbine shroud assembly having an internal flow passage that is in fluid communication with the internal flow passage of the stator vane. The system allows for reduced peak thermal gradients between a cooling medium provided by the cooling medium source and various turbine hardware components such as the turbine shroud assembly.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.

Abstract: Exciter circuitry includes a controller that receives a first signal requesting that a generator coupled to the exciter circuitry stop providing real power to an electrical grid. The controller also sends a second signal to a turbine control system of a turbine coupled to the generator to close at least one fuel nozzle, at least one inlet guide vane, or at least one variable stator vane in response to receiving the first signal. The controller further instructs the exciter circuitry to provide direct current (DC) voltage and DC current to a rotor of the generator, wherein the DC voltage and the DC current causes the generator to operate synchronously with the electrical grid.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.

Abstract: Embodiments of the present application relate to a method for recommending search phrases, a system for recommending search phrases, and a computer program product for recommending search phrases. A method for recommending search phrases is provided. The method includes obtaining subject terms and descriptive terms relating to the subject terms from title information, combining s subject term with a descriptive term to form a set of search phrases, calculating a first appraisal value for each search phrase, the calculating of the first appraisal value comprising multiplying term frequency of the search phrase with an inverse document frequency of the search phrase, determining a second appraisal value of each search phrase, combining the first appraisal value and the second appraisal value of each search phrase to obtain a publisher recommendation appraisal value for each search phrase, and selecting a recommended phrase.

Abstract: In one aspect the present subject matter is directed to a system for cooling a turbine engine. The system includes a cooling medium source, a stator vane having an internal flow passage that is in fluid communication with the cooling medium source and a turbine shroud assembly having an internal flow passage that is in fluid communication with the internal flow passage of the stator vane. The system allows for reduced peak thermal gradients between a cooling medium provided by the cooling medium source and various turbine hardware components such as the turbine shroud assembly.

Abstract: Content recommendation includes: determining a plurality of user behavior categories pertaining to a plurality of user behaviors by a plurality of users within a period of time, and a plurality of user behavior frequencies corresponding to the plurality of user behavior categories; determining whether the number of user behavior categories exceeds a preset category threshold; in the event that the number of user behavior categories exceeds the preset threshold, excluding one or more user behavior categories such that the number of remaining user behavior categories does not exceed the preset threshold; determining, based at least on the remaining user behavior categories and corresponding user behavior frequencies, user preference data comprising frequency distribution information of a plurality of pieces of content information targeted by user behaviors in the remaining user behavior categories; and recommending content information to a user based on the user preference data.

Abstract: A water delivery system for a gas turbine compressor having a plurality of blade stages positioned about a rotating shaft is provided. The plurality of blade stages are configured to compress an airflow. The water delivery system includes a nozzle system to inject water between at least one pair of the plurality of blade stages; and a controller controlling whether the water injected by the nozzle system is injected at a first pressure that augments power output during an operation mode of the plurality of blade stages and a second, lower pressure that washes at least some of blades of the plurality of blade stages during a wash mode of the plurality of blade stages.

Abstract: An injector, comprising, an injector body comprising, an inner wall that defines an injector cavity for fluid, at least one inlet channel into the injector cavity, and at least one outlet channel from the injector cavity, a plunger that defines at least one passageway between the injector cavity and the at least one outlet channel, the plunger being movable longitudinally in the injector cavity between at least: a first open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a first position, and a second open arrangement in which the at least one passageway is positioned to direct fluid into the at least one outlet channel at a second position different from the first position.

Abstract: Content recommendation includes: determining a plurality of user behavior categories pertaining to a plurality of user behaviors by a plurality of users within a period of time, and a plurality of user behavior frequencies corresponding to the plurality of user behavior categories; determining whether the number of user behavior categories exceeds a preset category threshold; in the event that the number of user behavior categories exceeds the preset threshold, excluding one or more user behavior categories such that the number of remaining user behavior categories does not exceed the preset threshold; determining, based at least on the remaining user behavior categories and corresponding user behavior frequencies, user preference data comprising frequency distribution information of a plurality of pieces of content information targeted by user behaviors in the remaining user behavior categories; and recommending content information to a user based on the user preference data.