Abstract: There is described an optical phase modulator generally having a substrate; a waveguide mounted to the substrate and extending along a path of the substrate, the waveguide having a first series of phase shift units distributed along the waveguide, each phase shift unit having two Bragg gratings being spaced apart from one another along the path and a cavity between the two spaced-apart Bragg gratings; and a modulation circuit configured for driving a length of the series of phase shift units of the waveguide in accordance with a modulation signal thereby modulating a refractive index of the waveguide to induce a phase shift to an optical signal propagating along the waveguide.

Abstract: The wind-wave complementary energy integrated system based on fixed foundation and generation and transmission method thereof pertains to the field of ocean renewable energy utilization, solving the problem of combining the wind and wave energy in a support structure, including a wind turbine, a tower, a wave energy device and a single pile foundation, the wind turbine is connected to the tower, and the single pile foundation is at the bottom of the tower, the single pile foundation is connected to the seabed, and the wave energy device is mounted on the tower near the sea surface. The effect is the renewable energy utilization rate and the energy conversion rate are effectively improved, thus reducing the cost to a certain extent and having high utility.

Abstract: There is described a polarimeter generally having a substrate; a polarization splitter on the substrate polarization splitting an incoming light beam into light beams; an interferometry circuit on the substrate forming polarization components from the light beams, and output waveguides outputting the polarization components.

Abstract: A zeolite membrane and a preparation method thereof are provided. The method includes: adding an organic binder solution dropwise to zeolite, and thoroughly grinding and stirring; blade-coating a resulting mixture on a substrate at a given thickness; and drying to obtain the zeolite membrane. The preparation of a zeolite membrane does not require a complicated hydrothermal crystal growth process, and the membrane can be prepared directly from natural zeolite or artificial zeolite. A prepared zeolite membrane has the characteristics of simple preparation process, low cost, prominent water permeability, high contaminant rejection rate and high zeolite load. The zeolite membrane, when used for the rejection of contaminants in water, can not only remove macromolecular contaminants in water, but also efficiently remove ammonia nitrogen by way of ion exchange, which is suitable for advanced treatment of wastewater.

Abstract: Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.

Abstract: The present invention provides a detection device of dot immunoblotting detection, including a negative pressure suction device, a hole plate, a hose for connecting the hole plate with the negative pressure suction device, and a nitrocellulose membrane in tight fit with the upper end surface of the hole plate. The present invention further provides a detection method of dot immunoblotting detection, including preparation, sample injection, blocking, incubation of a primary antibody, incubation of a secondary antibody, development and analysis. The detection method performs negative pressure suction through the negative pressure suction device, which is favorable for concentrating samples during sample injection and avoiding the influence, caused by cross contamination after diffusion of the samples, on an experimental result, and the experimental result is more accurate.

Abstract: Provided is a compound of formula I or II, a stereoisomer, a tautomer, a geometrical isomer, a solvate, an active metabolite, a hydrate, a prodrug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and the medical uses thereof in treating diseases benefiting from the capsid protein assembly inhibitor, particularly diseases caused by hepatitis B virus infection.

Abstract: The present invention discloses a high-peak-power single-frequency narrow-linewidth nanosecond fiber laser based on a triangular pulse, wherein the laser includes: pulsed laser generated by the laser seed injecting into a first power pre-amplifier through a first isolator, and then injecting into a second pre-amplifier and then injecting into a power amplifier; wherein triangle-shaped pulsed laser with fast rising edge is obtained by using electro-optic and acousto-optic modulator to modulate continuous wave single-frequency laser or a single-frequency semiconductor laser directly modulated by radio frequency signal; single-frequency triangle-shaped pulsed laser is employed as the laser source according to the characteristics of narrow intrinsic linewidth and suppression of linewidth broadening caused by SPM, and the power of pulsed laser is amplified through the MOPA system.

Abstract: A DC-DC converter includes: a transformer; first and second switching circuits, each coupled to one of two sides of the transformer, respectively, and each including at least two switches; a first current detection module, coupled to one side of the transformer and detecting a current at the side; a first conversion module, coupled to an output of the first current detection module, and converting a signal of the current received from the output to a voltage signal; a first comparison module comparing the voltage signal received from the output with a reference voltage signal, and generating a first modulation signal based on the comparison result; and a first controller generating a first control signal which is used for at least one switch in the second switching circuit and based on the first modulation signal and a drive signal of at least one switch in the first switching circuit.

Abstract: An optical device may include a substrate including a conductive core, a first layer stack on a first surface of the conductive core, a conductor-filled trench extending through the first layer stack to the conductive core such that the conductor-filled trench is on the first surface of the conductive core, and a second layer stack on a second surface of the conductive core. The optical device may include a vertical-cavity surface-emitting laser (VCSEL) chip above the conductor-filled trench. The VCSEL chip may include an array of VCSELs. A size of the conductor-filled trench may match a size of the VCSEL chip, match a size of an emission region of the array of VCSELs, or be greater than the size of the emission region of the array of VCSELs and less than the size of the VCSEL chip.

Abstract: The invention provides use of epalrestat in preparation of pancreatic cancer drugs. The pancreatic cancer drugs are used for inhibiting secretion of exosomes from pancreatic cancer cells. The invention also provides a method for verifying the inhibition effect of epalrestat on secretion of exosomes from pancreatic cancer cells. The method includes steps of: extracting cell supernatant exosomes by using a low-temperature ultracentrifugation method; lysing the collected exosomes, then using a BCA kit to quantify the resulting exosomal protein, and using the measured amount of the protein to reflect the amount of the exosomes; using a transmission electron microscope to verify a double-layer lipid membrane wrapped cup-shaped structure of the exosomes; and detecting exosome protein concentration by protein polyacrylamide gel electrophoresis with Coomassie brilliant blue. The invention provides a novel use of epalrestat, namely the inhibition of exosome secretion.

Abstract: A dimming glass includes: a first base substrate and a second base substrate that are oppositely disposed, a dye liquid crystal layer disposed between the first base substrate and the second base substrate, and at least one temperature sensor disposed between the first base substrate and the second base substrate. The at least one temperature sensor is configured to detect a temperature of the dye liquid crystal layer.

Abstract: An array of surface-emitting lasers is provided. The array outputs high brightness in a unipolar way. The array comprises a stress-adjustment unit and a plurality of epitaxial device units. The stress-adjustment unit is used to adjust stress. The stress from a substrate is used to select a laser mode for an aperture unit. The selection of the laser mode is enhanced for the aperture unit without sacrificing driving current. Low current operation is achieved in a single mode for effectively reducing volume and further minimizing the size of the whole array to achieve high-quality laser output. An object can be scanned by the outputted laser to obtain a clear image with a high resolution. Hence, the present invention is applicable for face recognition with high recognition and high security.

Abstract: A fingerprint recognition detection circuit includes an operational amplifier, an integrating capacitor and a first switch connected in series, and a second switch. A non-inverting input terminal of the operational amplifier is coupled to a reference voltage terminal, and an inverting input terminal of the operational amplifier is coupled to a fingerprint sensing capacitor. The integrating capacitor and the first switch are coupled between the inverting input terminal of the operational amplifier and an output terminal of the operational amplifier. The second switch is coupled between the inverting input terminal of the operational amplifier and the output terminal of the operational amplifier, and the second switch is connected in parallel with the integrating capacitor and the first switch connected in series.

Abstract: Provided is use of IL-15 protein complex joint PD-L1 antibody for treating tumor diseases.

Abstract: Itraconazole, a widely used antifungal drug, has been found to possess potent anti-angiogenic and anti-hedgehog activities, exhibiting promising antitumor activity in several human clinical studies. The wider use of itraconazole in the treatment of cancer, however, has been limited by its potent inhibition of the drug metabolic enzyme CYP3A4 which causes drug-drug interactions. In an effort to eliminate the CYP3A4 inhibition of itraconazole while retaining its anti-angiogenic activity, we synthesized a series of itraconazole derivatives. The newly synthesized analogs of itraconazole were evaluated for their cytotoxicity against human umbilical vein endothelial cells (HUVEC) and their inhibitory activity against CYP3A4 enzyme.

Abstract: A device control method is disclosed. When a first device and a second device are required to perform actions, a first instruction is sent to the first device, and a second instruction is sent to the second device after a first time interval; and when the first device, the second device, and a third device are required to perform actions, the first instruction is sent to the first device, the second instruction is sent to the second device after the first time interval, and a third instruction is sent to the third device after a second time interval, where the second time interval is greater than the first time interval, so that the third device performs a third action after a delay.

Abstract: In some implementations, a housing for an electro-optical device comprises a molded dielectric structural component, an electromagnetic interference (EMI) shield, and a plurality of conductive traces. The molded dielectric structural component may be configured to separate the EMI shield and the plurality of conductive traces.

Abstract: Technical solutions are described to implement a scalable write ahead log using a distributed file system. A general aspect includes a method for providing consistency among metadata replicas and content in an enterprise content management cluster. The method includes recording a transaction log entry in response to receiving a content modification request, the transaction log entry including a version identifier set to a first version value. The method also includes updating the transaction log entry to a second version value in response to successfully modifying content and one of a plurality of metadata replicas containing metadata corresponding to the request. The method also includes updating the transaction log entry to a third version value in response to successfully modifying each of the metadata replicas. The present document further describes examples of other aspects such as methods, computer products.

Abstract: A method for fabricating a semiconductor device includes providing a to-be-etched layer, including alternately arranged first regions and second regions along a first direction; forming a first mask layer on the to-be-etched layer; and forming a top mask layer on the first region and extending to the second region along the first direction. The projection pattern of the top mask layer divides the first mask layer formed on the first region into portions arranged in a second direction that is perpendicular to the first direction. The method further includes removing a portion of the first mask layer formed on the first region on both sides of the top mask layer to form a first trench. The first mask layer on the first region under the top mask layer forms a separation mask layer which divides the first trench into portions arranged in the second direction.