Abstract: This document provides methods and materials related to treating cancer. For example, methods and materials for using particles (e.g., nanoparticles) containing (a) one or more molecules having the ability to bind to a cancer cell (e.g., a human breast cancer cell) and (b) one or more molecules having the ability to bind to an APC (e.g., a human macrophage) to treat cancer are provided.

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Abstract: Disclosed are compounds of Formula (I) to (VIII): (I) (II) (III) (IV) (V) (VI) (VII) (VIII) or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate or prodrug thereof, wherein R3 is a tricyclic heteroaryl group substituted with R3a and zero to 2 R3b; and R1, R2, R3a, R3b, R4, and n are defined herein. Also disclosed are methods of using such compounds as PAR4 inhibitors, and pharmaceutical compositions comprising such compounds. These compounds are useful in inhibiting or preventing platelet aggregation, and are useful for the treatment of a thromboembolic disorder or the primary prophylaxis of a thromboembolic disorder.

Abstract: A heat-dissipating device configured to cool the battery pack of an electric vehicle includes a coolant circulating pump and a tank. The coolant circulating pump is configured to engage with the one or more heat dissipation pipes of the electric vehicle and communicate with the one or more heat dissipation pipes. The tank is configured to contain coolant which includes phase change material. When cooling is required, for example during battery recharging, the coolant circulating pump is configured to inject the coolant in the tank into the one or more heat dissipation pipes via the coolant inlet, drive the coolant to flow in the one or more heat dissipation pipes, and take the coolant out from the one or more heat dissipation pipes via the coolant outlet to the exterior. A related electric vehicle and a related heat dissipation method are also provided.

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are biased agonists, or ?-Arrestin agonists of the angiotensin II receptor, which may be used as medicaments.

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Abstract: The present disclosure is generally related to transformed host cells and their use for the production of branched-chain acyl-ACPs, branched-chain acyl-ACP-derived chemicals and fuels, branched-chain fatty acids and producing branched-chain fatty acid-derived chemicals and fuels. More particularly, disclosed herein are transformed host cells and methods for producing branched-chain acyl-ACPs and branched-chain fatty acids in high titer and high percentages. Also disclosed are methods for producing specific branched-chain fatty acid species and producing branched-chain fatty acid-derived chemicals and fuels such as, for example, branched-chain alcohols and branched-chain fatty acid ethyl esters.

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Abstract: In an approach to determining a relative position for each computer of a group of computers within a wireless network to a computer within the wireless network, a computer receives a set of digital image files from each computer and aggregates the set of digital image files into a panoramic digital image file. The computer generates a network map depicting a position of each of the computers based on the panoramic digital image file. The computer determines a relative position map for at least one computer based on the network map and the panoramic digital image file, wherein the relative position map provides a location of each computer of the group of computers with respect to the at least one computer. The computer receives input from the at least one computer, the input using the relative position map to send data to one or more of the group of computers.

Abstract: A housing includes a housing body formed with an engaging groove and a carrier device disposed in the housing body. The carrier device includes a carrier frame and a latching assembly. The carrier frame is configured to carry an electronic component and includes a pivoting sidewall rotatably pivoted to the housing body. The carrier frame is rotatable between a first position, where the carrier frame is disposed in the housing body, and a second position, where the carrier frame is pivoted out of the housing body. The latching assembly is disposed on the pivoting sidewall and is releasably engaged to the engaging groove so as to position the carrier frame at the second position.

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Abstract: The present invention is related to a switching device having a contactor and an actuator. The contactor has at least a first contactor member and a second contactor member. The actuator is configured to actuate the contactor. At least one of the contactor members has a varying or variable thickness along its length such that the at least one of the contactor members has a relatively thick portion and a relatively thin portion.

Abstract: This document provides methods and materials related to treating cancer. For example, methods and materials for using particles (e.g., nanoparticles) containing (a) one or more molecules having the ability to bind to a cancer cell (e.g., a human breast cancer cell) and (b) one or more molecules having the ability to bind to an APC (e.g., a human macrophage) to treat cancer are provided.

Abstract: An approach to determine a relative position for each computer of a group of computers within a wireless network to a computer within the wireless network, the approach includes a computer receiving a set of digital image files from each computer of the group of computers. The approach includes a computer aggregating the set of digital image files into a panoramic digital image file. The approach includes a computer generating a network map depicting a position of each of the computers within the wireless network based, at least in part, on the panoramic digital image file. The method includes a computer determining a relative position map for at least one computer based, on the network map and the panoramic digital image file, wherein the relative position map provides a location of each computer of the group of computers within the wireless network with respect to the at least one computer.

Abstract: In an approach to determining a relative position for each computer of a group of computers within a wireless network to a computer within the wireless network, a computer receives a set of digital image files from each computer and aggregates the set of digital image files into a panoramic digital image file. The computer generates a network map depicting a position of each of the computers based on the panoramic digital image file. The computer determines a relative position map for at least one computer based on the network map and the panoramic digital image file, wherein the relative position map provides a location of each computer of the group of computers with respect to the at least one computer. The computer receives input from the at least one computer, the input using the relative position map to send data to one or more of the group of computers.

Abstract: In an approach to determining a relative position for each computer of a group of computers within a wireless network to a computer within the wireless network, a computer receives a set of digital image files from each computer and aggregates the set of digital image files into a panoramic digital image file. The computer generates a network map depicting a position of each of the computers based on the panoramic digital image file. The computer determines a relative position map for at least one computer based on the network map and the panoramic digital image file, wherein the relative position map provides a location of each computer of the group of computers with respect to the at least one computer. The computer receives input from the at least one computer, the input using the relative position map to send data to one or more of the group of computers.

Abstract: A housing includes a housing body formed with an engaging groove and a carrier device disposed in the housing body. The carrier device includes a carrier frame and a latching assembly. The carrier frame is configured to carry an electronic component and includes a pivoting sidewall rotatably pivoted to the housing body. The carrier frame is rotatable between a first position, where the carrier frame is disposed in the housing body, and a second position, where the carrier frame is pivoted out of the housing body. The latching assembly is disposed on the pivoting sidewall and is releasably engaged to the engaging groove so as to position the carrier frame at the second position.

Abstract: In an approach to determining a relative position for each computer of a group of computers within a wireless network to a computer within the wireless network, a computer receives a set of digital image files from each computer and aggregates the set of digital image files into a panoramic digital image file. The computer generates a network map depicting a position of each of the computers based on the panoramic digital image file. The computer determines a relative position map for at least one computer based on the network map and the panoramic digital image file, wherein the relative position map provides a location of each computer of the group of computers with respect to the at least one computer. The computer receives input from the at least one computer, the input using the relative position map to send data to one or more of the group of computers.

Abstract: A plugging device includes a supporting frame having two opposite side plates disposed between front and rear ends thereof, at least one slide member adapted to be connected to one side of an electronic component and connected slidably to an inner surface of one of the side plates, and an operating member having at least one lever that includes a fulcrum portion connected pivotally to one of the side plates. When the operating member is pivoted rearwardly about the fulcrum portion, the slide member together with the electronic component is driven to slide relative to the supporting frame in a forward direction for plugging a plug electrical connector of the electronic component into a socket electrical connector.