Abstract: A switching device for shower system includes a housing; a valve core main body, wherein the valve core main body includes a first valve core and a second valve core, a first end of the first valve core is provided with a plurality of water passing holes in different positions, and a second end of the first valve core is slidably connected to the second valve core; a push rod, wherein the push rod is located inside the valve core main body, and an end of the push rod is inserted into the second valve core; and a switching assembly, wherein a first end of the switching assembly is slidably connected to the housing and a second end of the switching assembly is connected to the second valve core, when the switching assembly is pressed, the push rod is pushed to switch the water passing holes in different positions.

Abstract: Disclosed in the invention is a lithium battery production process, which comprises: through sequentially implemented processes of pre-compounding, winding for lamination, cutting, reclaiming material, continuously processing and assembling finished products, each electrode and separator are laminated, processed and formed, and finally assembled into a battery prefabricated product. The lithium battery production process is simple and efficient to implement, and it may realize continuous production of lithium battery products, thereby greatly improving battery production efficiency, and correspondingly simplifying the entire process flow to reduce the labor intensity of the staff. Also disclosed is a lithium battery production equipment for the above lithium battery production process.

Abstract: A method of estimating a speed of an object in real-time includes acquiring from an acceleration sensor mounted on the object a first original acceleration signal indicative of an acceleration of the object in a direction parallel to a travelling direction of the object, filtering the first original acceleration signal to remove noise to produce a first filtered acceleration signal, down-sampling the first filtered acceleration signal to obtain a first optimized acceleration signal, and calculating an estimated speed value of the object along the direction parallel to the travelling direction of the object based on the first optimized acceleration signal.

Abstract: The present invention relates to novel linkers containing a 2,3-disubstituted succinic group, or 2-monosubstituted, or 2,3-disubstituted fumaric or maleic (trans (E)- or cis (Z)-butenedioic), or acetylenedicarboxyl group for conjugation of a cytotoxic agent, and/or one or more different functional molecules per linker to a cell-binding molecule, through bridge linking pairs of thiols on the cell-binding molecule specifically. The invention also relates to methods of making such linkers, and of using such linkers in making homogeneous conjugates, as well as of application of the conjugates in treatment of cancers, infections and autoimmune disorders.

Abstract: The present disclosure provides a structure for aligning handle and mounting base of faucet and a widespread faucet including same. The structure for aligning handle and mounting base of a faucet includes: a water access main body, a cartridge, a mounting base, a handle, a first connecting element, and a second connecting element. A water inlet end of the cartridge is mounted in the water access main body. The mounting base is arranged around the water access main body and is provided with a first mounting hole. The handle is mounted on the cartridge and is provided with a second mounting hole. The first connecting element is inserted in the second mounting hole to fix the handle with a top end of the cartridge. The second connecting element is inserted in the first mounting hole to fix the mounting base with the water access main body.

Abstract: A semiconductor device includes a semiconductor body having a base region incorporating a field stop zone where the base region and the field stop zone are both formed using an epitaxial process. Furthermore, the epitaxial layer field stop zone is formed with an enhanced doping profile to realize improved soft-switching performance for the semiconductor device. In some embodiments, the enhanced doping profile includes multiple doped regions with peak doping levels where a first doped region adjacent to a first side of the field stop zone has a first peak doping level that is not higher than a last peak doping level of a last doped region adjacent to the base region. The epitaxial layer field stop zone of the present invention enables complex field stop zone doping profiles to be used to obtain the desired soft-switching characteristics in the semiconductor device.

Abstract: Transistor device and method of making thereof comprising a substrate heavily doped with a first conductivity type and an epitaxial layer lightly doped with the first conductivity type on top of the substrate. A body region doped with a second conductivity type is formed in the epitaxial layer wherein the second conductivity type is opposite the first conductivity type and a source region doped with the first conductivity type is formed in the body region of the epitaxial layer. An integrated planar-trench gate having a planar gate portion is formed on the surface of the epitaxial layer that is contiguous with a gate trench portion formed in the epitaxial layer.

Abstract: This invention relates to conjugates of camptothecin analogs with a cell-binding molecule of formula (I), wherein R1, R2, R3, R4, R5, X, L, n, m, T and ----- are defined herein. It also provides methods of making the conjugates of camptothecin analogs to a cell-binding agent, as well as methods of using the conjugates in targeted treatment of cancer, infection, and immunological disorders.

Abstract: An anode piece for a lithium battery having both high safety and high capacity, and a preparation method and a use therefor, the anode piece being mixed with a lithium-rich compound, the lithium-rich compound being at least one selected from lithium-rich manganese-based solid solution, a lithium-rich solid electrolyte or a lithium-separated silicon oxide. Li ions can be pulled away from the lithium-rich compound in extreme conditions such as overcharging, internal short circuiting, external short circuiting, thermal abuse, piercing, compressing or overheating, thereby filling in lithium vacancies in the anode material, stabilizing the crystal lattice structure of the anode material, improving safety performance in a battery manufactured by using the material, and allowing the anode piece to maintain excellent cycle performance at higher area capacities.

Abstract: The invention relates to a positive plate for a lithium battery, preparation method thereof and use in semi-solid state battery. The positive plate for a lithium battery comprises a current collector and an active material layer arranged on a surface of the current collector; and the active material layer comprises a positive electrode active material, a conductive agent, a binder, an oxide solid-state electrolyte and a polymer obtained by in-situ polymerization. The oxide solid-state electrolyte and polymer are evenly distributed in the active material layer; wherein the oxide solid-state electrolyte can effectively improve the safety performance of the positive plate; and the polymer obtained by in situ polymerization can effectively improve the contact between the oxide solid-state electrolyte and the material in the positive plate, thereby reducing the impedance of the positive plate and improving the electrochemical performance of the positive plate.

Abstract: The present disclosure provides a luminous water outlet device, which includes a hydroelectric power generation module, a waterway separation body, a waterway switching module, a water outlet panel, and a light board. The hydroelectric power generation module is arranged at a water inlet, the waterway separation body has two waterways, the waterway switching module is used to switch a flow of water in the two waterways, and the water outlet panel is correspondingly arranged below the two waterways, the light board is electrically connected with the hydroelectric power generation module. Compared with the prior art, the hydroelectric power generation module is arranged in the water inlet to ensure that the light board works no matter which waterway is opened and allows water to flow through. Further, the present disclosure has simpler installation, smaller volume, and simpler waterway structure.

Abstract: Described is a conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. Also described are a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.

Abstract: Described is a conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. Also described are a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.

Abstract: The present disclosure provides methods for determining adsorption isotherms for complex mixtures. In at least one embodiment, a method for obtaining adsorption isotherms for liquid mixtures includes providing a column comprising an adsorbent. The method includes delivering a composition to the column, the composition comprising a multi-component feed and a solvent. The method includes collecting a sample from the column and introducing the sample to a two dimensional gas chromatograph to determine a time-series concentration of one or more components of the sample. The method includes integrating the time-series concentration of at least one of the one or more components to determine an isotherm of the at least one component. The method includes obtaining quantitative information of the at least one component, based on the isotherm of the at least one component.

Abstract: Described is a conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. Also described are a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.

Abstract: An integrated wall-mounted base includes a wall-mounted base body which is provided with a water inlet connection part, a water outlet connection part, a upright column installation part, press-button switches, and a shower holder installation part. The water inlet connection part is connected to one water inlet pipe, the water outlet connection part is respectively connected to two water outlet pipes, the water inlet connection part is communicated with the water outlet connection part, and the press-button switches control opening and closing of flow passages of the two water outlet pipes. The upright column installation part is internally configured with a upright column for connecting and supporting a top shower, and an adjusting component is configured to fasten or release the upright column, as so to freely adjust a height of the upright column. The shower holder installation part is provided with a rotatable shower holder.