Patents by Inventor Xiao DING

Xiao DING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250214990
    Abstract: Described herein are DGKalpha inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with DGKalpha.
    Type: Application
    Filed: March 1, 2023
    Publication date: July 3, 2025
    Inventors: Hongfu LU, Huaxing YU, Xiao DING, Feng REN
  • Publication number: 20250214967
    Abstract: Provided herein are FAK degraders, e.g., a compound of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a disorder, disease, or condition mediated by an FAK.
    Type: Application
    Filed: March 29, 2023
    Publication date: July 3, 2025
    Inventors: Xiao Ding, Jinxin Liu, Liena Qin, Feng Ren
  • Publication number: 20250197405
    Abstract: Providing compounds of Formula (A) or pharmaceutically acceptable salts, solvate, stereoisomer, or isotopic variant thereof useful as PKMYT1 inhibitors, pharmaceutical compositions comprising the same, and use thereof in the manufacture of medicaments for treating PKMYT1-associated diseases or conditions such as advanced solid tumor, and etc.
    Type: Application
    Filed: March 15, 2023
    Publication date: June 19, 2025
    Applicant: INSILICO MEDICINE IP LIMITED
    Inventors: Yazhou Wang, Xiao Ding, Min Zheng, Feng Ren
  • Patent number: 12334109
    Abstract: The present invention discloses a video processing circuit, which is coupled to a memory chip and includes an image processing circuit. The image processing circuit includes a first channel, a second channel and a compression circuit. The two channels process first image data and second image data to generate first processed image data and second processed image data, respectively. The compression circuit compresses the first processed image data and the second processed image data to generate first compressed image data and second compressed image data, respectively. A memory block in the memory chip is configured as a ring buffer shared by the first channel and the second channel so as to store the first compressed image data and the second compressed image data.
    Type: Grant
    Filed: March 13, 2023
    Date of Patent: June 17, 2025
    Assignee: SIGMASTAR TECHNOLOGY LTD.
    Inventor: Xiao-Ding Zhu
  • Publication number: 20250188094
    Abstract: Described herein are PKMYT1 (Myt1) inhibitors and pharmaceutical compositions comprising said inhibitors. The compounds and compositions are useful for the treatment of a disease or disorder associated with PKMYT1.
    Type: Application
    Filed: March 17, 2023
    Publication date: June 12, 2025
    Inventors: Xiao DING, Feng REN, Yazhou WANG, Min ZHENG
  • Patent number: 12321193
    Abstract: Aspects of the present disclosure include system, methods, and software for buffer insertions. In one example, a method includes receiving a clock signal network layout, the clock signal network layout comprising a clock source electrically coupled to a plurality of clock sinks via a plurality of net segments, a first hierarchy that bounds a first region of the clock signal network layout, and a second hierarchy that bounds a second region of the clock signal network layout. The method additionally includes creating a graph representative of the clock signal network layout, the graph comprising a plurality of logical edges, and identifying a to-be-inserted buffer location comprising a location on a net segment of the plurality of net segments to insert a buffer. The method further includes selecting a selected logical edge to insert the buffer based on the to-be-inserted buffer location, the first hierarchy, the second hierarchy, or a combination thereof.
    Type: Grant
    Filed: July 5, 2023
    Date of Patent: June 3, 2025
    Assignee: Cadence Design Systems, Inc.
    Inventors: Yi-Xiao Ding, Sheng-En David Lin, Natarajan Viswanathan, Charles Jay Alpert
  • Publication number: 20250162241
    Abstract: A 3D printing system and method for mitigating the force needed to separate a transparent printing membrane from a most-recently photocured layer of resin on a sample secured to a platform. The membrane is coupled to an actuator and a pivot joint adapted to rotate the membrane into the resin, and the platform is coupled to a vertical stage adapted to translate the platform downward. Through simultaneous activation of the actuator and the vertical stage, the membrane is progressively peeled away from the sample. The system and method are suitable for various membrane-based 3D printing technologies including large-area projection micro stereolithography (P?SL).
    Type: Application
    Filed: February 22, 2023
    Publication date: May 22, 2025
    Applicant: BMF Nano Material Technology Co., Ltd.
    Inventors: Liangkang Fu, Chen Yang, Xiao Ding, Chunguang Xia
  • Publication number: 20250163077
    Abstract: Described herein are PKMYT1 (Myt1) inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with PKMYT1.
    Type: Application
    Filed: February 17, 2023
    Publication date: May 22, 2025
    Inventors: Xiao DING, Feng REN, Yazhou WANG, Min ZHENG
  • Publication number: 20250145632
    Abstract: The present invention discloses a pyrimidine heterocyclic compound, and a preparation method and medical use thereof. Specifically, the present invention discloses a pyrimidine heterocyclic compound with a structure shown in Formula (A) or a pharmaceutically acceptable salt thereof (groups are each defined in the specification), a pharmaceutical composition comprising the compound, and use of the compound in treatment of cell proliferative diseases (such as cancers).
    Type: Application
    Filed: December 21, 2022
    Publication date: May 8, 2025
    Inventors: Hongfu LU, Jingjing PENG, Xiao DING, Jinxin LIU, Yingtao LIU, Feng REN, Fusheng ZHOU, Tao JIANG, Tao LIANG, Jiong LAN, Qiang LU
  • Publication number: 20250145624
    Abstract: Described herein are PKMYT1 (Myt1) inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with PKMYT1.
    Type: Application
    Filed: February 17, 2023
    Publication date: May 8, 2025
    Inventors: Xiao DING, Fanye MENG, Feng REN, Yazhou WANG, Min ZHENG
  • Publication number: 20250136596
    Abstract: Described herein are PKMYT1 (Myt1) inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with PKMYT1.
    Type: Application
    Filed: February 17, 2023
    Publication date: May 1, 2025
    Inventors: Xiao DING, Yangguang LI, Yingtao LIU, Fanye MENG, Feng REN, Yazhou WANG, Min ZHENG
  • Publication number: 20250107063
    Abstract: Example three-dimensional (3D) memory devices, methods, and memory systems for connecting vertical transistors and capacitors using connect structures are disclosed. One example method includes forming a first structure that includes multiple vertical transistors. A connect layer is formed over the first structure. The connect layer is etched to form connect structures, where each of the connect structures is coupled to a corresponding one of the vertical transistors. Multiple capacitors are formed over the connect layer, where each of the plurality of capacitors is coupled to a respective connect structure.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 27, 2025
    Inventors: Hao ZHANG, Fandong LIU, Si QIAO, Yanhong WANG, Xiao DING, Wei LIU, Wenyu HUA
  • Publication number: 20250086460
    Abstract: Disclosed are a method and apparatus for compressing a topology recognition model, an electronic device, and a medium. The method includes: pruning a to-be-compressed model to obtain a pruned model, and training the pruned model to obtain a trained pruned model; quantifying a bit quantity of a weight parameter of each neural network layer in the trained pruned model from a first bit quantity to a second bit quantity to obtain a highly-quantified pruned model, and training the highly-quantified pruned model to obtain a trained highly-quantified pruned model; using the trained highly-quantified pruned model as the to-be-compressed model, continuously pruning and quantifying the to-be-compressed model until a compressed topology recognition model is obtained, and deploying the compressed topology recognition model on an Internet of Things in Power Systems (IOTIPS) terminal, to reduce a size of the topology recognition model while ensuring the topology recognition model meets an accuracy requirement.
    Type: Application
    Filed: August 9, 2023
    Publication date: March 13, 2025
    Inventors: Jianan Yuan, Chao Huo, Huifeng Bai, Ganghong Zhang, Jian Gao, Libin Zheng, Huadong Yu, Zhibin Yin, Anqin Luo, Fan Xie, Yifan Shen, Shuangshuang Yang, Xiao Ding
  • Patent number: 12221606
    Abstract: Compositions and methods for using nucleosome interacting protein domains to increase accessibility of programmable DNA modification proteins to target chromosomal sequences, thereby increasing efficiency of targeted genome/epigenetic modification in eukaryotic cells.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: February 11, 2025
    Assignee: Sigma-Aldrich Co. LLC
    Inventors: Fuqiang Chen, Xiao Ding, Yongmei Feng, Gregory Davis
  • Publication number: 20250042890
    Abstract: Described herein are MAT2A inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with MAT2A.
    Type: Application
    Filed: October 19, 2022
    Publication date: February 6, 2025
    Inventors: Chiachun CHEN, Xiao DING, Xiaosong LIU, Qinguan MENG, Feng REN, Hailong WANG
  • Publication number: 20250034132
    Abstract: Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of inflammatory bowel disease.
    Type: Application
    Filed: October 28, 2022
    Publication date: January 30, 2025
    Inventors: Xiao DING, Liena QIN, Feng REN, Jianyu XU
  • Patent number: 12209101
    Abstract: Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of anemia.
    Type: Grant
    Filed: August 31, 2023
    Date of Patent: January 28, 2025
    Assignee: INSILICO MEDICINE IP LIMITED
    Inventors: Xiao Ding, Liena Qin, Feng Ren, Jianyu Xu
  • Publication number: 20250011300
    Abstract: The present invention relates to compounds of formula (I), wherein R1, R2, R3, Y, Q1, Q2, Q3, Q4 and Q5 are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: October 24, 2022
    Publication date: January 9, 2025
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Fabian Dey, Xiao Ding, Houguang Shi, Xuefei Tan, Jun Wu, Jiamin Zheng, Mingwei Zhou
  • Patent number: 12185521
    Abstract: Embodiments of the disclosure provide a method for manufacturing a memory device, the method includes operations. At least one cell block is formed on a wafer, each of the at least one cell block includes multiple memory cells distributed in an array, each of the multiple memory cells includes a transistor and a storage capacitor connected to a source of the transistor. Bit lines are formed on the wafer, and each of the bit lines is connected to a drain of the transistor, here each of the bit lines and the storage capacitor are located on opposite surfaces of the wafer in a thickness direction respectively. A peripheral circuit is formed above the bit lines on the wafer along a perpendicular of the wafer, here the peripheral circuit includes at least a Sensing Amplifier (SA). An electrical connection is formed between the bit line and the SA.
    Type: Grant
    Filed: August 6, 2021
    Date of Patent: December 31, 2024
    Assignee: ICLEAGUE TECHNOLOGY CO., LTD.
    Inventors: Wenyu Hua, Fandong Liu, Xiao Ding
  • Publication number: 20240417387
    Abstract: The present invention relates to compounds of formula (I), wherein R1 to R3, A, Q1, Q2, W and X are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: December 20, 2021
    Publication date: December 19, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Kurt Amrein, Fabian Dey, Xiao Ding, Xinyi Huang, Christian Lerner, Houguang Shi, Xuefei Tan, Jun Wu, Jiamin Zheng, Mingwei Zhou