Abstract: The present invention provides methods for screening and diagnosing prostate cancer based on a correlation between cancer cell growth, cancer lethality or recurrence and the expression level of ZFP36 or NEDD9 and PTEN in conjunction with ZFP36. The disclosure also provides methods for screening and diagnosing prostate cancer based on a correlation between cancer lethality and the genotype of rs1910301 SNP. Also provided are methods for treating prostate cancer comprising providing a treatment or monitoring based on the expression level of ZFP36, the expression level of NEDD9, and the expression level of ZFP36 in conjunction with PTEN levels or the genotype of rs1910301 SNP.

Abstract: This invention in one aspect relates to a mixed-kernel heterojunction transistor, comprising a monolayer film formed of an atomically thin material, and a network of carbon nanotubes (CNTs) vertically stacked over the monolayer film to define an overlap region of the CNT network with the monolayer film, and non-overlap regions of the monolayer film and the CNT network, wherein the overlap region is a mixed-kernel van der Waals heterojunction.

Abstract: The present invention relates to a compound of formula (I) capable of inhibiting plasmin activity and having blood coagulation and hemostasis activity, and a pharmaceutically acceptable salt, hydrate, isomer, prodrug and mixture thereof, wherein R1 to R3 are as defined in the description.

Abstract: A method for regulating an unmanned aerial vehicle (UAV) includes receiving a UAV identifier and one or more types of contextual information broadcasted by the UAV. The UAV identifier uniquely identifies the UAV from other UAVs. The one or more types of contextual information includes at least geographical information of the UAV. The method further includes authenticating, via an authentication device, an identity of the UAV based on the UAV identifier to determine whether the UAV is authorized for operation, and transmitting a signal to a remote device in response to determining whether the UAV is authorized for operation.

Abstract: A continuously variable transmission with both equal-difference output and equal-ratio output includes an input mechanism, a hydraulic transmission mechanism, a planetary-gear-set convergence mechanism, an equal-difference output mechanism, an equal-ratio output mechanism, a clutch assembly, and a brake. The clutch assembly connects an output end of the input mechanism to an input end of the hydraulic transmission mechanism and the planetary-gear-set convergence mechanism and connects an output end of the hydraulic transmission mechanism to the planetary-gear-set convergence mechanism. The clutch assembly connects the planetary-gear-set convergence mechanism to the equal-difference output mechanism and the equal-ratio output mechanism. The clutch assembly connects the equal-ratio output mechanism to the equal-difference output mechanism.

Abstract: A continuously variable transmission with both equal-difference output and equal-ratio output includes an input mechanism, a hydraulic transmission mechanism, a planetary-gear-set convergence mechanism, an equal-difference output mechanism, an equal-ratio output mechanism, a clutch assembly, and a brake. The clutch assembly connects an output end of the input mechanism to an input end of the hydraulic transmission mechanism and the planetary-gear-set convergence mechanism and connects an output end of the hydraulic transmission mechanism to the planetary-gear-set convergence mechanism. The clutch assembly connects the planetary-gear-set convergence mechanism to the equal-difference output mechanism and the equal-ratio output mechanism. The clutch assembly connects the equal-ratio output mechanism to the equal-difference output mechanism.

Abstract: A method for removing stale context in a service instance, comprising: generating a user message according to UID and request instruction of received request data; routing the user message to first service instance; if target context corresponding to the user ID is saved in a global cache of a database, loading the target context from the global cache: when the loaded target context does not belong to the first service instance, setting the loaded target context to belong to the first service instance, wherein the set target context is saved into a first local cache and the global cache; and instructing to remove one or more invalid target contexts corresponding to the user ID from one or more other service instances, wherein the invalid target contexts are target contexts which do not belong to the first service instance, such that stale contexts which are the invalid target context are removed.

Abstract: Methods and apparatus for processing a substrate are provided herein. For example, a physical vapor deposition processing chamber comprises a chamber body defining a processing volume, a substrate support disposed within the processing volume and comprising a substrate support surface configured to support a substrate, a power supply configured to energize a target for sputtering material toward the substrate, an electromagnet operably coupled to the chamber body and positioned to form electromagnetic filed lines through a sheath above the substrate during sputtering for directing sputtered material toward the substrate, and a controller operably coupled to the physical vapor deposition processing chamber for controlling the electromagnet based on a recipe comprising a pulsing schedule for pulsing the electromagnet during operation to control directionality of ions relative to a feature on the substrate.

Abstract: The present invention discloses a vibration capsule, including: an enclosure, a vibration motor, a battery assembly, and a control assembly. The vibration motor, the battery assembly and the control assembly are disposed within the enclosure, the vibration motor and the battery assembly are electrically connected to the control assembly. The control assembly includes a first PCB and a second PCB, disposed at opposite ends of the battery assembly, a connecting structure that connects the first PCB and the second PCB, and a plurality of electronic devices disposed on one side of the first PCB away from the battery assembly, and/or on one side of the second PCB away from the battery assembly. The present invention achieves that there is no relative tilt between the control assembly and the battery assembly, ensuring coaxial alignment between the control assembly and the battery assembly.

Abstract: The present invention discloses a number of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

Abstract: Disclosed are a foldable screen and a display device. The foldable screen includes: a flexible display panel and a plurality of elastic portions, wherein each of the elastic portions includes each of elastic support members and two connecting rods fixedly connected to each of the elastic support members; wherein the two connecting rods are respectively connected to two flat portions of the flexible display panel, and the elastic support members are configured to supply a support force to the foldable portion in the case that a display surface of the foldable portion of the flexible display panel is coplanar with those of the flat portions.

Abstract: Disclosed herein are heterocyclic compounds, for example, according to the following formula and analogs thereof: that inhibit the activity of FLT3. Also described are specific covalent inhibitors of FLT3. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the FLT3 inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of proliferative diseases or conditions, including hematological malignancies and other diseases or conditions dependent on FLT3 activity.

Abstract: A conjugate compounds or pharmaceutically acceptable salt thereof, comprises a payload and two or more kinds of cell-interacting molecules. The cell-interacting molecules are ligands capable of specifically binding to a cell surface receptor. A method of treating diseases, comprises delivering a payload to a subject.

Abstract: The present disclosure provides an apparatus and a method for hydrate-based wastewater treatment and cold storage. The apparatus for hydrate-based wastewater treatment and cold storage includes a water chilling unit, a hydrate-based cold storage tank, an airflow disturbance device, a water layer positioning system, a spraying system, a suction filtration system, a heat exchange system, and a system monitoring device. The water chilling unit provides a secondary refrigerant at a low temperature. The secondary refrigerant flows through an evaporator coil in the hydrate-based cold storage tank for heat exchange. The airflow disturbance device induces hydrate nucleation. The water layer positioning system positions a contact surface between a water layer and a hydrate former after hydrate decomposition to facilitate drawing and separation of the treated upper water layer. The spraying system and the suction filtration system enhance the solid-liquid separation efficiency to improve the removal rate of pollutants.

Abstract: Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds.

Abstract: The present disclosure relates to an image processing method. The method may include: obtaining image data; reconstructing an image based on the image data, the image including one or more first edges; obtaining a model, the model including one or more second edges corresponding to the one or more first edges; matching the model and the image; and adjusting the one or more second edges of the model based on the one or more first edges.

Abstract: Provided are use of a rare earth amino acid complex, a polylactic acid composition and a preparation method thereof. The rare earth amino acid complex is formed by complexing a rare earth metal ion with an amino acid; a rare earth element corresponding to the rare earth metal ion is one or more selected from the group consisting of lanthanum, cerium and samarium; and the amino acid is at least one selected from the group consisting of proline, L-phenylalanine, tyrosine and tryptophan.

Abstract: Embodiments of the present disclosure relate to methods and apparatuses for a pre-emption check procedure for a sidelink transmission in 3 GPP (3rd Generation Partnership Project) 5G networks. According to an embodiment of the present disclosure, a method performed by a user equipment (UE) includes: receiving, from another UE, information associated with a pre-emption check procedure on another reserved resource of the abovementioned UE; and making an adjustment relating to a transmission on a reserved resource of the UE according to the information.

Abstract: Provided by a bandpass filter circuit and a multiplexer. The bandpass filter circuit includes at least one electromagnetic LC filter circuit and at least one acoustic wave resonance unit. The at least one acoustic wave resonance unit includes an input port, an output port, at least one circuit element and at least three resonators. The at least one electromagnetic LC filter circuit is electrically connected to the at least one acoustic wave resonance unit, and the at least three resonators include at least one first resonator and at least one second resonator. In a case where the at least one first resonator includes one first resonator, the first resonator is connected in series between the input port and the output port.