Abstract: The present invention discloses a number of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

Abstract: Methods for depositing a dielectric oxide layer atop one or more substrates disposed in or processed through a PVD chamber are provided herein. In some embodiments, such a method includes: sputtering source material from a target assembly onto a first substrate while the source material is at a first erosion state and while providing a first amount of RF power to the target assembly to deposit a dielectric oxide layer onto a first substrate having a desired resistance-area; and subsequently sputtering source material from the target assembly onto a second substrate while the source material is at a second erosion state and while providing a second amount of RF power to the target assembly, wherein the second amount of RF power is lower than the first amount of RF power by a predetermined amount calculated to maintain the desired resistance-area.

Abstract: Aminopyrimidine containing compounds that inhibit both Mer tyrosine kinase (MerTK) activity and Tyro3 kinase activity are disclosed herein. Additionally disclosed are methods of synthesis and use of the aminopyrimidine containing compounds as anti-cancer agents, immunostimulatory and immunomodulatory agents, anti-platelet agents, anti-infective agents, and as adjunctive agents.

Abstract: The present invention provides a genus of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

Abstract: To generate training data based on normal content and anomalous content generated from the normal content. A training data generation method for generating training data used for generating a learned model for determining whether there is an anomaly in an inspection target, the training data generation method including: receiving normal content regarding the inspection target and anomalous content generated from the normal content; and generating training data based on a set of the normal content and one or more pieces of the anomalous content.

Abstract: This application disclosures a method and system for detecting a centerline of a vessel. The method may include obtaining image data, wherein the image data may include vessel data; selecting two endpoints of the vessel based on the vessel data; transforming the image data to generate a transformed image based on at least one image transformation function; and determining a path of the centerline of the vessel connecting the first endpoint of the vessel and the second endpoint of the vessel to obtain the centerline of the vessel based on the transformed image. The two endpoints of the vessel may include a first endpoint of the vessel and a second endpoint of the vessel.

Abstract: Embodiments of the disclosure provide systems and methods for providing random access to segmented and encrypted or compressed data stored in a repository. Retrieving at least a portion of a file stored in a repository can comprise storing a plurality of files in the repository. A request to retrieve at least a portion of one of the plurality of files can be received and object metadata for the requested one of the plurality of files can be obtained. A determination can be made based on the obtained metadata as to whether the requested one of the plurality of files is a multipart file. In response to determining the requested one of the plurality of files is not a multipart file, a single file retrieval process performing and in response to determining the requested one or the plurality of files is a multipart file, a multipart retrieval process can be performed.

Abstract: Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds.

Abstract: An aluminum alloy based on a total weight of the aluminum alloy, in percentages by weight, includes 9.12% of Si, 8-11% of Zn, 0.5-1.5% of Mg, 0.2-0.8% of Cu, 0-0.6% of Fe, 0.08-0.25% of Mn, 0-0.10% of Sr, 0-0.05% of Sc, 0-0.5% of Er, and 73.2-82.22% of Al.

Abstract: A method of forming a tunnel layer of a magnetoresistive random-access memory (MRAM) structure includes forming a first magnesium oxide (MgO) layer by sputtering an MgO target using radio frequency (RF) power, exposing the first MgO layer to oxygen for approximately 5 seconds to approximately 20 seconds at a flow rate of approximately 10 sccm to approximately 15 sccm, and forming a second MgO layer on the first MgO layer by sputtering the MgO target using RF power. The method may be performed after periodic maintenance of a process chamber to increase the tunnel magnetoresistance (TMR) of the tunnel layer.

Abstract: An array substrate, a method for manufacturing an array substrate, and a display device are provided. The array substrate includes a first substrate, a first common electrode layer, a second common electrode layer, a frame sealing adhesive and a conductive adhesive. The first common electrode layer is disposed at an edge of the first substrate and is in a grid shape; the second common electrode layer is disposed at an inner side the first common electrode layer, and includes a light-transmitting portion provided in a grid shape, and a gate insulating layer is provided on the light-transmitting portion. The frame sealing adhesive is disposed on the first common electrode layer. The conductive adhesive is disposed in the frame sealing adhesive and partially extends onto the gate insulating layer corresponding to the light-transmitting portion. The conductive adhesive is configured to electrically connect with a common electrode of a color filter substrate.

Abstract: The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.

Abstract: The present disclosure relates to systems and methods for image processing. The methods may include determining structure data associated with the tissue based on at least one original image of a tissue. The methods may further include determining at least one stenosis region of the tissue based on the structure data associated with the tissue. At least one of the structure data and/or the at least one stenosis region of the tissue may be configured to be displayed on a display device.

Abstract: The present disclosure discloses to a method for determining optimum preservation temperature of a sulfur autotrophic denitrifying bacteria biofilm, and belongs to the technical field of environment engineering. The method of the present disclosure comprises: determining the cell activity state of a sulfur autotrophic denitrifying bacteria biofilm preserved at different temperatures by flow cytometry, and determining the preservation temperature of the cell activity state closest to the cell activity state of the sulfur autotrophic denitrifying bacteria in pilot operation as the optimum preservation temperature. The cell activity state and performance effect are verified to be reliable after activity recovery by the test data.

Abstract: A tungsten-base alloy material and a preparation method therefor. The preparation method comprises: 1) evenly grinding composite powder containing tungsten and zirconium oxide, and then performing annealing treatment at 700-1000° C. to obtain powder A; and 2) grinding and then compression moulding the powder A, and then performing liquid-phase sintering to obtain a tungsten-base alloy blank so as to obtain the tungsten-base alloy material.

Abstract: A method for regulating an unmanned aerial vehicle (UAV) includes receiving a UAV identifier and one or more types of contextual information broadcasted by the UAV. The UAV identifier uniquely identifies the UAV from other UAVs. The one or more types of contextual information includes at least geographical information of the UAV. The method further includes authenticating, via an authentication device, an identity of the UAV based on the UAV identifier to determine whether the UAV is authorized for operation, and transmitting a signal to a remote device in response to determining whether the UAV is authorized for operation.

Abstract: The disclosure provides an oil tubing installation assembly and a scroll compressor adopting the same. The oil tubing installation assembly is adapted to be installed into a shell in a vertical direction and includes: a housing on which a vertical oil tubing installation surface and an oil hole located in the oil tubing installation surface are provided; a clip adapted to be installed on the oil tubing installation surface and into the shell along with the housing; and an oil tubing assembly adapted to be installed into the clip in a vertical direction after the housing and the clip have been installed into the shell. The oil tubing assembly includes an oil tubing body and a cuboid-shaped installation block. A through hole is provided in the installation block and the through hole is configured to have a first orifice on the front surface of the installation block and a second orifice on the rear surface of the installation block. The upper end of the oil tubing body is connected to the first orifice.

Abstract: Embodiments of a tantalum (Ta) target pasting process for deposition chambers using RF powered processes include pasting at least a portion of the inner surfaces of the process chamber with Ta after using RF sputtering to deposit dielectric material on a wafer. Pressure levels within the process chamber are adjusted to maximize coverage of the Ta pasting layer. The Ta pasting encapsulates the dielectric material that has been inadvertently sputtered on the process chamber inner surfaces such as the shield. Oxygen is then flowed into the process chamber to form a tantalum oxide layer on the Ta pasting layer to further reduce contamination and particle generation.

Abstract: A biological nitrogen removal method based on multistage feeding and anoxic/aerobic chambers for adopting a constant flow operation mode, enabling wastewater subjected to primary treatment to enter a first-stage and a second-stage A/O reaction units from two position points; lifting and refluxing an effluent to an influent end of the first-stage units; lifting and refluxing an effluent to an influent end of the second-stage units; and clarifying, separating and discharging an effluent from an outlet end of a third-stage A/O reaction unit. The wastewater treatment mode combines a process based on two-stage wastewater feeding and three-stage anoxic/aerobic chambers with biofilms in different reaction zones, =optimizing and controlling a reflux ratio of each segment according to an amount of organic matters available for denitrification in influent, reducing the impact of hydraulic loading at the cross section in the reactors while removing organic matters and nitrogen-containing pollutants at a low temperature.

Abstract: An embodiment of a semiconductor package apparatus may include technology to pre-process an image to simplify a background of the image, and perform object detection on the pre-processed image with the simplified background. For example, an embodiment of a semiconductor package may include technology to pre-process an image to subtract the background from the image and perform object detection on the pre-processed image with the background subtracted. Other embodiments are disclosed and claimed.