Abstract: The present disclosure provides raw material re-feeding apparatus for manufacturing a monocrystal and monocrystal manufacturing apparatus including the same. The raw material re-feeding apparatus is provided outside a monocrystal furnace and includes a storage and a feeder in communication with the storage. A discharging end of the feeder is located in the monocrystal furnace and movable relative to the monocrystal furnace, so that the discharging end of the feeder is immersed in a silicon melt when the material re-feeding is performed, and thus the material is melted and re-fed.

Abstract: The present disclosure relates to methods and apparatuses for groupcast connection establishment and transmission. According to an embodiment of the present disclosure, a method can include: transmitting, from a first user equipment, first information for a groupcast connection establishment; receiving, at the first user equipment, second information for the groupcast connection establishment from a second user equipment, wherein the second information comprises identity information of the second user equipment; and transmitting, from the first user equipment, third information for the groupcast connection establishment to the second user equipment, wherein the third information indicates whether the groupcast connection establishment is successful. Embodiments of the present disclosure propose a novel groupcast connection establishment procedure, which can meet the advanced V2X service requirements.

Abstract: The present invention relates to a bispecific antibody-drug conjugate comprising a bispecific antibody, a toxin, and a linker, and to a pharmaceutical composition comprising the bispecific antibody-drug conjugate, and a use of the bispecific antibody-drug conjugate and the pharmaceutical composition thereof in the preparation of medicaments for preventing and/or treating cancer. The bispecific antibody comprises a first paratope capable of recognizing and/or binding to domain II of HER2, and a second paratope capable of recognizing and/or binding to domain IV of HER2; the toxin is selected from the group consisting of maytansines, hemiasterlins, amanitins, auristatins, calicheamicins and duocarmycins; the linker is a cleavable linker or a non-cleavable linker; alternatively, one or more hydrogen atoms in the toxin and/or linker are optionally deuterated.

Abstract: A hygienic assembly and a hygienic robot. The hygienic assembly includes a housing adapted to be connected to a reduction box of a joint of the robot, an opening, and a flange having a first end for connecting to an output member of the reduction box and a second end for connecting to an end effector. The assembly also includes a seal member which includes an outer ring fixed to an inner circumferential surface of the opening and a seal lip slidably contacting an outer circumferential surface of the flange.

Abstract: A gear-hydraulic-rhombic pyramid integrated multi-mode hybrid transmission device includes an input assembly, a hydraulic transmission mechanism, a front planetary gear mechanism, a rhombic pyramid-type continuously variable transmission mechanism, a rear planetary gear mechanism, an output assembly, a clutch assembly, and a brake assembly. The clutch assembly connects an output end of the input assembly to an input end of the hydraulic transmission mechanism and an input end of the front planetary gear mechanism. The clutch assembly connects an output end of the hydraulic transmission mechanism to the front planetary gear mechanism and the rear planetary gear mechanism. The clutch assembly connects the front planetary gear mechanism, the rhombic pyramid-type continuously variable transmission mechanism, the rear planetary gear mechanism, and the output assembly in sequence. The clutch assembly and the brake assembly provide a continuous transmission ratio between the input assembly and the output assembly.

Abstract: A two-gear and dual-motor driven hybrid power transmission device and a transmission method therefore are provided, belonging to the technical field of transmissions. An input end of an input shaft is connected to an engine power system, and an output end of the input shaft is connected to a front-end motor by means of a front-row planetary gear train. The front-row planetary gear train is connected to one end of a first clutch, another end of the first clutch is connected to an input end of an output shaft, and an output end of the output shaft is connected to a rear axle of a vehicle. The output shaft is connected to a rear-end motor by means of a rear-row planetary gear train, and the rear-row planetary gear train is connected to a second clutch and a third clutch.

Abstract: Some embodiments of the present disclosure provide methods and systems for determining a hemodynamic parameter. The method may include: obtaining image data of a subject being acquired in a rest state; obtaining a trained machine learning model; and determining, based on the trained machine learning model, at least one target hemodynamic parameter of the subject. The trained machine learning model may be obtained based on multiple sets of sample image data. Each set of the multiple sets of sample image data may include a first image data and at least one of a second image data or a third image data. The first image data may be acquired in a rest state of a first sample subject, the second image data may be acquired in a hyperemic state of the first sample subject, and the third image data may be acquired in a hyperemic state of a second sample subject including the first sample subject.

Abstract: Embodiments of the present disclosure provide a collapsible wheelchair, including: a movable chassis; a chair; a chair backrest; at least one first folding mechanism, installed between the movable chassis and the chair; and at least one second folding mechanism, connected between the chair and the chair backrest; where, the at least one first folding mechanism and the at least one second folding mechanism are connected in series and both have a four-rod linkage structure, and when the collapsible wheelchair is switched from a folded state to an open state or from the open state to the folded state, the at least one first folding mechanism and the at least one second folding mechanism are configured to move simultaneously. The collapsible wheelchair provided by the present disclosure is convenient in terms of the operation and easy to operate.

Abstract: The present invention provides a method for achieving high availability of stream control transport protocol (SCTP) connection in a microservice system. The microservice system comprises at least one access network and a core network. The access network includes at least one base station comprising at least one SCTP peer. The core network includes at least one non-SCTP-capable microservice instance acting as a SCTP service client, multiple SCTP-capable microservice instances, a service node manager and a service delegator.

Abstract: A biological nitrogen removal method based on multistage feeding and anoxic/aerobic chambers for adopting a constant flow operation mode, enabling wastewater subjected to primary treatment to enter a first-stage and a second-stage A/O reaction units from two position points; lifting and refluxing an effluent to an influent end of the first-stage units; lifting and refluxing an effluent to an influent end of the second-stage units; and clarifying, separating and discharging an effluent from an outlet end of a third-stage A/O reaction unit. The wastewater treatment mode combines a process based on two-stage wastewater feeding and three-stage anoxic/aerobic chambers with biofilms in different reaction zones, =optimizing and controlling a reflux ratio of each segment according to an amount of organic matters available for denitrification in influent, reducing the impact of hydraulic loading at the cross section in the reactors while removing organic matters and nitrogen-containing pollutants at a low temperature.

Abstract: An omni wheel, comprising a hub bracket (10) and roller components (20). Each roller component (20) comprises a first roller assembly (21) and a second roller assembly (22); the first roller assembly (21) comprises a roller bracket (211) and a first roller structure; the second roller assembly (22) comprises a second shaft (221) and a second roller structure, and the second shaft (221) comprises a second shaft body (2211) and a limiting portion (2212); and the second shaft body (2211) is connected and locked to a first connection structure (2111) to limit the second roller structure between the limiting portion (2212) and the first connection structure (2111). A moving device is further disclosed. The omni wheel can ensure that second rollers will not shake and oscillate during running of the omni wheel and thus reduce vibrations and noise of the omni wheel, improving the running stability.

Abstract: The present invention provides methods for screening and diagnosing prostate cancer based on a correlation between cancer cell growth, cancer lethality or recurrence and the expression level of ZFP36 or NEDD9 and PTEN in conjunction with ZFP36. The disclosure also provides methods for screening and diagnosing prostate cancer based on a correlation between cancer lethality and the genotype of rs1910301 SNP. Also provided are methods for treating prostate cancer comprising providing a treatment or monitoring based on the expression level of ZFP36, the expression level of NEDD9, and the expression level of ZFP36 in conjunction with PTEN levels or the genotype of rs1910301 SNP.

Abstract: A method for regulating an unmanned aerial vehicle (UAV) includes receiving a UAV identifier and one or more types of contextual information broadcasted by the UAV. The UAV identifier uniquely identifies the UAV from other UAVs. The one or more types of contextual information includes at least geographical information of the UAV. The method further includes authenticating, via an authentication device, an identity of the UAV based on the UAV identifier to determine whether the UAV is authorized for operation, and transmitting a signal to a remote device in response to determining whether the UAV is authorized for operation.

Abstract: A method for removing stale context in a service instance, comprising: generating a user message according to UID and request instruction of received request data; routing the user message to first service instance; if target context corresponding to the user ID is saved in a global cache of a database, loading the target context from the global cache: when the loaded target context does not belong to the first service instance, setting the loaded target context to belong to the first service instance, wherein the set target context is saved into a first local cache and the global cache; and instructing to remove one or more invalid target contexts corresponding to the user ID from one or more other service instances, wherein the invalid target contexts are target contexts which do not belong to the first service instance, such that stale contexts which are the invalid target context are removed.

Abstract: Methods and apparatus for processing a substrate are provided herein. For example, a physical vapor deposition processing chamber comprises a chamber body defining a processing volume, a substrate support disposed within the processing volume and comprising a substrate support surface configured to support a substrate, a power supply configured to energize a target for sputtering material toward the substrate, an electromagnet operably coupled to the chamber body and positioned to form electromagnetic filed lines through a sheath above the substrate during sputtering for directing sputtered material toward the substrate, and a controller operably coupled to the physical vapor deposition processing chamber for controlling the electromagnet based on a recipe comprising a pulsing schedule for pulsing the electromagnet during operation to control directionality of ions relative to a feature on the substrate.

Abstract: The present invention discloses a number of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

Abstract: Disclosed herein are heterocyclic compounds, for example, according to the following formula and analogs thereof: that inhibit the activity of FLT3. Also described are specific covalent inhibitors of FLT3. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the FLT3 inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of proliferative diseases or conditions, including hematological malignancies and other diseases or conditions dependent on FLT3 activity.

Abstract: Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds.