Abstract: Composite particles of the present invention include alumina particles and an inorganic coating disposed on a surface of the alumina particles, the alumina particles containing molybdenum (Mo), the inorganic coating including a composite metal oxide.

Abstract: A cross reality system enables any of multiple devices to efficiently access previously stored maps. Both stored maps and tracking maps used by portable devices may have any of multiple types of location metadata associated with them. The location metadata may be used to select a set of candidate maps for operations, such as localization or map merge, that involve finding a match between a location defined by location information from a portable device and any of a number of previously stored maps. The types of location metadata may prioritized for use in selecting the subset. To aid in selection of candidate maps, a universe of stored maps may be indexed based on geo-location information. A cross reality platform may update that index as it interacts with devices that supply geo-location information in connection with location information and may propagate that geo-location information to devices that do not supply it.

Abstract: The invention relates to a CTC3.0-based locomotive decoupling and coupling plan automatic generation and execution method. According to the method, by upgrading a track occupancy display terminal and a data platform in a CTC3.0 system, automatic generation of a locomotive decoupling or coupling plan is triggered when the route display terminal receives a train plan, so as to complete a locomotive decoupling or coupling task. The method has the advantages of high automation degree and high transportation efficiency.

Abstract: Provided are a search method and apparatus, and an electronic device and a storage medium. The method comprises: receiving a generic query search request, the generic query search request carrying a generic query term; acquiring at least one multimedia content card corresponding to the generic query term, wherein each multimedia content card corresponds to an extension tag corresponding to the generic query search request, each multimedia content card comprises information of a plurality of multimedia content sets; and presenting information of the plurality of multimedia content sets comprised in each multimedia content card of the at least one multimedia content card. Search results related to a generic query term can be clustered from various dimensions and presented, such that a user can directly find content related to a search intention of the user, thereby improving the search efficiency and shortening a search path.

Abstract: A laser wireless power transmission device and method based on power acquisition on power line. The device includes a power transmitter and a power receiver both installed on a power transmission line. The power transmitter includes an online induction power acquisition module, a semiconductor laser, a communication module, a two-dimensional pan-tilt, a beam shaping module, a control unit, a video image module, and an IMU module. The power receiver includes a four-quadrant photovoltaic panel, a DCDC module, a wireless monitoring module, and a battery.

Abstract: The disclosure discloses a linker compound, a polyethylene glycol-linker conjugate and a derivative thereof, and a polyethylene glycol-linker-drug conjugate. The linker compound as well as the conjugate thereof with the polyethylene glycol and the derivative thereof may be used for modifying a drug, and a modification reaction is simple and easy to carry out. Moreover, a reaction yield is high, and an application range of the modified drug is wide. The modified drugs gradually degrade from a chain of the conjugate in vivo, and may stay in a lesion (such as a cancer site) for a longer period of time, achieving purposes of sustained and controlled release, reducing an administration frequency, and greatly improving a bioavailability of the drug and a patient compliance.

Abstract: An antitumor pharmaceutical composition and an application thereof. Active ingredients of the antitumor pharmaceutical composition contain a polyethylene glycol-modified camptothecin derivative (in particular, polyethylene glycol-modified irinotecan) and temozolomide. It is proved by means of animal experiments that the administration of polyethylene glycol-modified camptothecin derivative (in particular, polyethylene glycol-modified irinotecan) and temozolomide in combination has an extremely strong treatment effect on tumors (such as neuroblastoma), and the tumor inhibition rate can reach 98% and is significantly superior to that of a monotherapy group; thus, the provided antitumor pharmaceutical composition has better application prospects for treatment of tumors.

Abstract: The present invention provides a composition of a polyethylene glycol maleimide derivative and a polymerization inhibitor. In particular, the present invention provides a composition of an 8-arm polyethylene glycol maleimide derivative and a phenolic polymerization inhibitor. The ingredient and content of the polymerization inhibitor in the composition are reasonably chosen, thereby significantly increasing stability of the polyethylene glycol maleimide derivative, effectively avoiding the undesirable effect of gel solidifying due to polymerization during storage and transportation, and extending a pot life and shelf life of a product thereof.

Abstract: The invention discloses a humic acid type adsorption material as well as a preparation method and application thereof. The humic acid type adsorption material is prepared by taking carboxymethyl cellulose or salts thereof, humate and montmorillonite as raw materials and adding a monomer, a cross-linking agent and an initiator through aqueous solution polymerization. The synthesized porous material is great in specific surface area, can quickly get close to water molecules in water to form hydrogen bonds, and finally achieves the purpose of removing organic dye pollutants through electrostatic attraction effect with dye molecules. The humic acid type adsorption material is low in raw material price, is simple in synthesis process, and is green and environmentally friendly.

Abstract: A cross reality system enables any of multiple devices to efficiently access previously stored maps. Both stored maps and tracking maps used by portable devices may have any of multiple types of location metadata associated with them. The location metadata may be used to select a set of candidate maps for operations, such as localization or map merge, that involve finding a match between a location defined by location information from a portable device and any of a number of previously stored maps. The types of location metadata may prioritized for use in selecting the subset. To aid in selection of candidate maps, a universe of stored maps may be indexed based on geo-location information. A cross reality platform may update that index as it interacts with devices that supply geo-location information in connection with location information and may propagate that geo-location information to devices that do not supply it.

Abstract: Provided are an interfering RNA for inhibiting gene expression of an epidermal growth factor receptor (EGFR for short) and an application of the interfering RNA. The interfering RNA is siRNA, comprises nucleotide sequences of GCAACAUGUCGAUGGACUU and/or AAGUCCAUCGACAUGUUGC, can effectively inhibit the gene expression of the EGFR, and provides a new choice for preventing or treating EGFR-related diseases (particularly EGFR-related cancers).

Abstract: A system is provided for classifying an instruction sequence with a machine learning model. The system may include at least one processor and at least one memory. The memory may include program code that provides operations when executed by the at least one processor. The operations may include: processing an instruction sequence with a trained machine learning model configured to detect one or more interdependencies amongst a plurality of tokens in the instruction sequence and determine a classification for the instruction sequence based on the one or more interdependencies amongst the plurality of tokens; and providing, as an output, the classification of the instruction sequence. Related methods and articles of manufacture, including computer program products, are also provided.

Abstract: The disclosure provides a multi-arm multi-claw polyethylene glycol derivative suitable for click chemistry reactions of general formula I, wherein R is a polyethylene glycol residue having a linear-chain structure, a Y-type structure or a multi-branched structure, R1, R2 and R3 are linking groups, P is an terminal group of non-azido non-alkynyl group, D is —N3 or —C?CH, l is selected from an integer of 1 to 20, and m is selected from an integer of 0 to 19.

Abstract: A PEG linker as represented by formula (I), wherein n and m are respectively an integer from 1 to 7, providing the PEG linker with 1 to 49 linking sites. A ligand drug conjugate as represented by formula (II). The conjugate uses the PEG linker to increase a drug loading capacity and drug loading diversity, thereby improving pharmaceutical efficacy.

Abstract: An apparatus configured to be worn on a head of a user, includes: a screen configured to present graphics to the user; a camera system configured to view an environment in which the user is located; and a processing unit configured to determine a map based at least in part on output(s) from the camera system, wherein the map is configured for use by the processing unit to localize the user with respect to the environment; wherein the processing unit of the apparatus is also configured to obtain a metric indicating a likelihood of success to localize the user using the map, and wherein the processing unit is configured to obtain the metric by computing the metric or by receiving the metric.

Abstract: An electronic apparatus and a method for reducing the number of commands are provided. The electronic apparatus includes a central processor and a co-processor. The central processor generates a plurality of original register setting commands to set at least one bit of at least one register of the co-processor. The original register setting commands include a plurality of first original register setting commands, and a plurality of setting targets of the first original register setting commands have address continuity. The central processor merges the first original register setting commands to generate at least one merged register setting command. The central processor transmits the at least one merged register setting command to the co-processor.

Abstract: An electronic apparatus and a method for reducing the number of commands are provided. The electronic apparatus includes a central processor and a co-processor. The central processor generates a plurality of original register setting commands to set at least one bit of at least one register of the co-processor. The original register setting commands include a plurality of first original register setting commands, and a plurality of setting targets of the first original register setting commands have address continuity. The central processor merges the first original register setting commands to generate at least one merged register setting command. The central processor transmits the at least one merged register setting command to the co-processor.

Abstract: An apparatus configured to be worn on a head of a user, includes: a screen configured to present graphics to the user; a camera system configured to view an environment in which the user is located; and a processing unit configured to determine a map based at least in part on output(s) from the camera system, wherein the map is configured for use by the processing unit to localize the user with respect to the environment; wherein the processing unit of the apparatus is also configured to obtain a metric indicating a likelihood of success to localize the user using the map, and wherein the processing unit is configured to obtain the metric by computing the metric or by receiving the metric.

Abstract: A method of training a reinforcement machine learning computer system. The method comprises providing a machine-learning computer programming language including a pre-defined plurality of reinforcement machine learning criterion statements, and receiving a training specification authored in the machine-learning computer programming language. The training specification defines a plurality of training sub-goals with a corresponding plurality of the reinforcement machine learning criterion statements supported by the machine-learning computer programming language. The method further comprises computer translating the plurality of training sub-goals from the training specification into a shaped reward function configured to score a reinforcement machine learning model configuration with regard to the plurality of training sub-goals.

Abstract: The invention discloses use of a conjugate of polyethylene glycol and a local anesthetic in non-anesthetic analgesia. A local anesthetic is prepared into a prodrug or a sustained release preparation, wherein a high molecular polymer such as polyethylene glycol in the prodrug is covalently bonded with a local anesthetic, and auxiliary materials with a sustained release effect in the sustained release preparation are non-covalently bonded to the local anesthetic. After administration, there is no anesthesia and analgesic effect before the release of the free local anesthetic. After the free local anesthetic is released, an analgesic effect is achieved.