Abstract: In one aspect there is provided a method. The method may include: determining that an executable implements a sub-execution environment, the sub-execution environment being configured to receive an input, and the input triggering at least one event at the sub-execution environment; intercepting the event at the sub-execution environment; and applying a security policy to the intercepted event, the applying of the policy comprises blocking the event, when the event is determined to be a prohibited event. Systems and articles of manufacture, including computer program products, are also provided.

Abstract: In some implementations there may be provided a system. The system may include a processor and a memory. The memory may include program code which causes operations when executed by the processor. The operations may include analyzing a series of events contained in received data. The series of events may include events that occur during the execution of a data object. The series of events may be analyzed to at least extract, from the series of events, subsequences of events. A machine learning model may determine a classification for the received data. The machine learning model may classify the received data based at least on whether the subsequences of events are malicious. The classification indicative of whether the received data is malicious may be provided. Related methods and articles of manufacture, including computer program products, are also disclosed.

Abstract: A hotspot correction method is provided. The layout patterns in the hotspot regions are accurately corrected by using an ILT method. Then the layout patterns in the extension regions are corrected by using an OPC method. As a result, the layout patterns in the hotspot regions can be accurately corrected while pattern distortion of the extension regions generated due to the regional ILT correction can be prevented. Moreover, high demanding of calculation capability and long calculation time of global ILT correction can be avoided.

Abstract: An activating agent for the treatment of radioactive wastewater. The activating agent is prepared by dissolving a mixture of inorganic salts including Ca2+, Na+, Sr2+, Zn2+, Mg2+, Fe2+ and K+ in pure water having an electrical resistivity greater than 0.5 M?·cm to yield a solution. A method of radioactive wastewater treatment using the activating agent includes: 1) preparing the activating agent; 2) adding the activating agent to radioactive wastewater having an electrical resistivity greater than 0.5 M?·cm; uniformly mixing the activating agent and the radioactive wastewater; 3) further treating the radioactive wastewater including the activating agent using an electro-deionization device; and 4) collecting two liquid flows obtained in 3), one being purified water, the other being concentrated water returning to 2) for further purification.

Abstract: A PEG linker as represented by formula (I), wherein n and m are respectively an integer from 1 to 7, providing the PEG linker with 1 to 49 linking sites. A ligand drug conjugate as represented by formula (II). The conjugate uses the PEG linker to increase a drug loading capacity and drug loading diversity, thereby improving pharmaceutical efficacy.

Abstract: A hotspot correction method is provided. The layout patterns in the hotspot regions are accurately corrected by using an ILT method. Then the layout patterns in the extension regions are corrected by using an OPC method. As a result, the layout patterns in the hotspot regions can be accurately corrected while pattern distortion of the extension regions generated due to the regional ILT correction can be prevented. Moreover, high demanding of calculation capability and long calculation time of global ILT correction can be avoided.

Abstract: Provided are a polyol glyceryl ether, and a multi-armed polyethylene glycol and the multi-armed polyethylene glycol active derivative prepared using the same. The multi-armed polyethylene glycol is formed by polymerizing ethylene oxide with the polyol glyceryl ether as an initiator, and has the structure of general formula II, wherein B is a polyol group, n is an integer between 3 and 22, PEG is the same or not the same —(OCH2CH2)m—, and the average value of m is an integer between 3 and 250. The multi-armed polyethylene glycol has a relatively low poly-dispersity and a relatively high determined molecular weight. Also provided is a conjugate of the multi-armed polyethylene glycol active derivative and pharmaceutical molecules, a pharmaceutical composition comprising the conjugate, and a gel formed by the multi-armed polyethylene glycol active derivative. The gel can be used to prepare a sustained-release drug for prolonging the time of the drug action.

Abstract: Disclosed is a Y-type discrete polyethylene glycol derivative as shown by Formula (I). The Y-type discrete polyethylene glycol derivative has the advantages of a determined molecular weight and number of segments in the chain, and can avoid the defects where the polyethylene glycol derivative itself is a mixture and the molecular weight is not homogeneous. The Y-type polyethylene glycol of the present invention can solve the problem of insufficient water solubility caused by an increase in the loading capacity when the discrete polyethylene glycol modifies an insoluble drug while increasing the drug loading capacity.

Abstract: A method to segment images that contain multiple objects in a nested structure including acquiring an image; defining the multiple objects by layers, each layer corresponding to one region, where a region contains an innermost object and all the objects nested within the innermost object; stacking the layers in an order of the nested structure of the multiple objects, the stack of layers having at least a top layer and a bottom layer; extending each layer with padded nodes; connecting the top layer to a sink and the bottom layer to a source, wherein each intermediate layer between the top layer and the bottom layer are connected only to the adjacent layer by undirected links; and measuring a boundary length for each layer.

Abstract: Differing from the fact that the amount of register units and adder units arranged in conventional moving average filter must be increased for processing more number of reference input signals, the present invention particularly discloses a moving average low-pass filtering device. The moving average low-pass filtering device comprises a register unit and a filtering and processing unit, and is able to use identical circuit architecture to successfully treat reference input signals with a filtering process even if the number of the reference input signals is alternatively increased. Moreover, after finishing a verification experiment by a simulator, simulation results have proved that, this novel moving average low-pass filtering device still can use identical circuit architecture to complete the filtering process under nearly the same calculation efficiency even though the number of the reference input signals is alternatively increased.

Abstract: In some implementations there may be provided a system. The system may include a processor and a memory. The memory may include program code which causes operations when executed by the processor. The operations may include analyzing a series of events contained in received data. The series of events may include events that occur during the execution of a data object. The series of events may be analyzed to at least extract, from the series of events, subsequences of events. A machine learning model may determine a classification for the received data. The machine learning model may classify the received data based at least on whether the subsequences of events are malicious. The classification indicative of whether the received data is malicious may be provided. Related methods and articles of manufacture, including computer program products, are also disclosed.

Abstract: The present disclosure discloses an actuator, comprising a first torsion spring body and a second torsion spring body, each of the first torsion spring body and the second torsion spring body comprising: an inner ring; an outer ring; and a plurality of elastic units, connected in parallel between the inner ring and the outer ring. An outer ring of the first torsion spring body and an outer ring of the second torsion spring body are rigidly connected, and an inner ring of the first torsion spring body and an inner ring of the second torsion spring body are aligned with each other. The actuator further includes a motor element and a braking element. The motor element is for providing an output torque, and is connected with the inner ring of the first torsion spring body. The braking element is for providing a braking torque, and is connected with the inner ring of the second torsion spring body.

Abstract: Under one aspect, a method is provided for protecting a device from a malicious file. The method can be implemented by one or more data processors forming part of at least one computing device and can include extracting from the file, by at least one data processor, sequential data comprising discrete tokens. The method also can include generating, by at least one data processor, n-grams of the discrete tokens. The method also can include generating, by at least one data processor, a vector of weights based on respective frequencies of the n-grams. The method also can include determining, by at least one data processor and based on a statistical analysis of the vector of weights, that the file is likely to be malicious. The method also can include initiating, by at least one data processor and responsive to determining that the file is likely to be malicious, a corrective action.

Abstract: The present invention provides compounds represented by formula (I) and pharmaceutical acceptable salts thereof, preparation method therefor and pharmaceutical composition containing the compounds represented by formula (I) and pharmaceutical acceptable salts thereof. In the compounds of the present invention, each terminal group of polyethylene glycol molecule can bond with a plurality of rapamycin molecules by cactus oligopeptide, with the loading rate of the pharmaceutical being increased. The compounds can be used to induce immunosuppression and treat graft rejection, autoimmune disease, solid tumors, fungal infection, and cardiovascular and cerebrovascular disease.

Abstract: Provided are polyethylene glycol drug conjugates of general formula (I), (II) or (III) and pharmaceutical compositions and a use thereof. The conjugates are formed by combining low molecular weight polyethylene glycol with 2-4 drug molecules. The conjugates can interact with receptor dimers or polymers, thereby improving the in vivo distribution of the drug, changing the oil and water distribution coefficient, enhancing the pharmacological activity, reducing the blood-brain barrier permeability of the drug, and improving the bioavailability of the drug.

Abstract: Provided are polyethylene glycol drug conjugates of general formula (I), (II) or (III) and pharmaceutical compositions and a use thereof. The conjugates are formed by combining low molecular weight polyethylene glycol with 2-4 drug molecules. The conjugates can interact with receptor dimers or polymers, thereby improving the in vivo distribution of the drug, changing the oil and water distribution coefficient, enhancing the pharmacological activity, reducing the blood-brain barrier permeability of the drug, and improving the bioavailability of the drug.

Abstract: A method of treatment of radioactive wastewater. The method includes: allowing radioactive wastewater to undergo reverse osmosis treatment and continuous electrodeionization treatment in sequence. The continuous electrodeionization treatment is carried out in a continuous electrodeionization unit including a continuous electrodeionization membrane stack including a dilute chamber and a concentrate chamber. The dilute chamber is filled with between 30 and 60 vol. % of a first strong-acid cation exchange resin, between 40 and 60 vol. % of a first strong-base anion exchange resin, and between 0 and 30 vol. % of a weak-base anion exchange resin. The concentrate chamber is filled with between 20 and 50 vol. % of a second strong-acid cation exchange resin, and the rest is a second strong-base anion exchange resin.

Abstract: Provided is a multi-arm polyethylene glycol-azido derivative of general formula I, wherein R is a central molecule, which is selected from a polyhydroxy structure, a polyamino structure or a polycarboxyl structure; n is the number of branches or arms, n?3; PEG is the same or different —(CH2CH2O)m—, the average value of m being an integer from 3 to 250; X is a linking group of a azido end group; k is the number of the branches having the azido end group; F is selected from the group consisting of amino, carboxyl, sulfhydryl, ester group, maleic imide group and acrylic group; and Y is a linking group of an end group F.

Abstract: Provided are polyethylene glycol drug conjugates of general formula (I), (II) or (III) and pharmaceutical compositions and a use thereof. The conjugates are formed by combining low molecular weight polyethylene glycol with 2-4 drug molecules. The conjugates can interact with receptor dimers or polymers, thereby improving the in vivo distribution of the drug, changing the oil and water distribution coefficient, enhancing the pharmacological activity, reducing the blood-brain barrier permeability of the drug, and improving the bioavailability of the drug.

Abstract: Provided are polyethylene glycol drug conjugates of general formula (I), (II) or (III) and pharmaceutical compositions and a use thereof. The conjugates are formed by combining low molecular weight polyethylene glycol with 2-4 drug molecules. The conjugates can interact with receptor dimers or polymers, thereby improving the in vivo distribution of the drug, changing the oil and water distribution coefficient, enhancing the pharmacological activity, reducing the blood-brain barrier permeability of the drug, and improving the bioavailability of the drug.