Abstract: Provided are novel linker compounds and ligand-drug conjugates, and more specifically to linker compounds comprising a short polypeptide and use thereof in preparation of ligand-drug conjugates, ligand-drug conjugates comprising the linker, and preparation and use thereof. The novel linker compounds improve the coupling efficiency of the ligand-drug conjugates as well as the homogeneity and overall stability of the conjugates, further improving the efficacy and safety of the ligand-drug conjugates.

Abstract: A solar cell and a photovoltaic module are provided. The solar cell includes a substrate provided with a first face and a second face, at least one of which is a side of the substrate. On shared prismatic edges and/or shared corners where the first surface and the second surface are adjacent, the substrate is also provided with a multiple-pyramid shared body having a shared face. When viewed in the direction towards the first surface, the multiple-pyramid shared body includes a first pyramid structure formed by enclosing several first triangular surfaces and several third triangular surfaces. When viewed in the direction towards the second surface, the multiple-pyramid shared body includes a second pyramid structure formed by enclosing several second triangular surfaces and several third triangular surfaces.

Abstract: An electronic device package comprises a substrate with a first side and a second side opposite the first side; a first conductive feature on the first side and having a first surface; a first dielectric material in contact with the first surface, wherein the first dielectric material has a first composition comprising silicon and nitrogen; a second conductive feature on the second side of the substrate and having a second surface; and a second dielectric material in contact with the second surface, wherein the second dielectric material has a second composition different than the first composition, and wherein a surface roughness of the second surface is greater than a surface roughness of the first surface.

Abstract: An electronic device is provided. The electronic device includes an ultra-wideband (UWB) communication circuit including at least one antenna for acquiring signals from an external electronic device, a processor operatively connected with the UWB communications circuit, and memory operatively connected with the processor. The memory may store one or more instructions which, when executed, cause the processor to obtain at least one signal from the at least one antenna, determine a phase-difference-of-arrival of the at least one signal, obtain information related to the state of the electronic device, obtain a calibration value corresponding to the obtained state information of the electronic device from the memory, and determine the angle-of-arrival of the at least one signal based on the phase-difference-of-arrival of the at least one signal and the calibration value.

Abstract: The present application belongs to battery materials, and in particular, to a lithium-containing multi-phosphate cathode material and a preparation method therefor, and a secondary battery. The lithium-containing multi-phosphate cathode material includes a single-core multi-shell lithium manganese iron phosphate composite material, the composite material includes a core of lithium iron phosphate or lithium manganese iron phosphate, N lithium manganese iron phosphate coating layers coated on an outer surface of the core, and a carbon coating layer coated on an outermost layer of the composite material; N is an integer greater than or equal to 1; a manganese content in the N lithium manganese iron phosphate coating layers successively increases in a radially outward direction, and a particle size of the lithium manganese iron phosphate particles in the N lithium manganese iron phosphate coating layers successively decreases in the radially outward direction.

Abstract: Valves, systems, articles, and methods for controlling fluid flow are generally described. According to some aspects, valves that can move between an open configuration and a closed configuration in response to a change in magnetic field and/or voltage potential are provided. According to certain aspects, valves comprising elastic diaphragms comprising magnetic materials (e.g., an elastic composite material including magnetic nanoparticles or other magnetic materials dispersed in a matrix) and/or electroactive polymers are provided. In some aspects, magnetically actuated systems and/or voltage potential actuated systems comprising elastomeric valves are described. In some embodiments, valves and systems described herein are useful for liquid handling, dosing, and regulation of fluid flow, though embodiments in which the disclosed valves are used in different applications are also contemplated.

Abstract: An electronic device according to an embodiment of the disclosure may include: a communication circuit, and at least one processor, comprising processing circuitry, electrically coupled to the communication circuit.

Abstract: A method, device and medium for step size calibration of a two-dimensional scanning module in a scanning light field imaging system are provided. The method includes: collecting the two-dimensional raw scanning light field data at the initial scanning step size, and rearranging into four-dimensional phase space data to obtain multi-view rearranged images; selecting the middle views of all views in the multi-view rearranged images to obtain non-scanned central view sub-images; calculating the sub-pixel displacement matrix of all non-scanned central view sub-images relative to the first non-scanned central view sub-image; calculating the average displacement quantity according to the sub-pixel displacement matrix, and calculating the step size adjustment coefficient according to the average displacement quantity; and updating the correct scanning step size according to the step size adjustment coefficient.

Abstract: Devices and systems with diamond substrates bonded to integrated circuits, and methods of forming the same, are disclosed herein. In one example, a microelectronic assembly includes a semiconductor substrate, a diamond substrate, a first dielectric layer on the semiconductor substrate, and a second dielectric layer on the diamond substrate, where the second dielectric layer is bonded to the first dielectric layer.

Abstract: A field-of-view leveling method for an ultra-large field-of-view microscope including an electric cylinder, a lens and a microscope stage, is provided. The microscope stage includes an X-axis and a Y-axis for controlling deflection of the stage around the X- and Y-axes. The method includes: S1: performing microscopic image acquisition on a to-be-photographed sample at an initial angle through the lens to obtain an initial microscopic image; S2: performing microscopic image acquisition at several angles within a set deflection angle range on the X-axis to obtain several deflected microscopic images; S3: after each angle deflection, performing microscopic image registration and cropping on the deflected microscopic image according to the initial microscopic image; S4: calculating clarity of the microscopic images at the initial angle and several angles; and S5: with the X-axis optimal angle used as a reference, repeating S2 to S4 to adjust and obtain the Y-axis optimal angle.

Abstract: A comprehensive energy supply system with a hydrogen production prediction and calculation function and integrated with hydrogen energy storage by residual flue gas of a gas engine is provided. When a total amount of discharged flue gas is larger than a first amount of flue gas required by a chiller/heater, remaining flue gas is introduced into the exhaust gas waste heat boiler for generating steam. A second amount of flue gas discharged from the hydrogenation reaction combustion furnace and entering the exhaust gas waste heat boiler is determined so as to calculate a total amount of intake flue gas into the exhaust gas waste heat boiler. A required amount of natural gas raw material is calculated according to the mass flow of steam and a total carbon flow in natural gas, and natural gas is introduced into the furnace according to the amount of natural gas raw material.

Abstract: A quaternary ammonium-functionalized poly(arylene ether sulfone) copolymer for moisture-swing CO2 capture, and a method for producing the same, is disclosed. The copolymer includes a polysulfone copolymer having a copolymerization unit based on diallyl bisphenal A (DABA) and has quaternary ammonium functionalities. The method for preparation of a quaternary ammonium-functionalized poly(arylene ether sulfone) copolymer includes reacting diallyl bisphenol A (DABA) with bisphenol A (BPA) and 4,4?-difluorodiphenyl sulfone (DFDPS) to form an allyl-modified poly(arylene ether sulfone) (PAES-co-APAES) copolymer, then modifying the PAES-co-APAES copolymer to convert the allyl functionalities to tertiary amines, forming tertiary amine-modified PAES (PAES-co-TAPAES) copolymer. The method also includes converting the tertiary amine of the PAES-co-TAPAES copolymer to quaternary ammonium, forming quaternary ammonium-modified PAES.

Abstract: Disclosed is a circuit board for a camera module including a circuit board body and at least two lateral connecting belts, wherein the lateral connecting belts are led out from the side surfaces of the circuit board body and bend upwards, and, after being bent, extend on the side surfaces of a camera module to form lateral connecting belt bodies, an outer surface of a hard plate of one of the lateral connecting belts is provided with a plurality of bonding pads, and the hard plate of the other lateral connecting belt has a plurality of conductive holes, so that the movement resistance of a circuit board body and a photosensitive chip can be reduced, while the yield and production efficiency are improved.

Abstract: A large-volume 3D image stitching method, device, computer equipment, and medium are provided. The method includes following steps: acquiring a to-be-stitched 3D image stack matrix Vstack, and extracting to-be-stitched boundaries of to-be-stitched sub-3D images; performing fusion calculation through a sigmoid function on adjacent to-be-stitched boundaries of all adjacent to-be-stitched sub-3D images to obtain smooth boundaries; performing boundary cropping, tensor reshaping and shape transformation on the to-be-stitched 3D image stack matrix Vstack according to the to-be-stitched boundaries to obtain a 3D matrix; and correspondingly applying all smooth boundaries to boundary junctions in the 3D matrix to obtain a seamlessly stitched 3D image.

Abstract: This application provides the structure of an x-ray tube that produces a sequence of linear x-ray sources. An x-ray tube includes a rotatable member having a rotation axis and a helical fin rigidly attached to the rotatable member. The helical fin is configured to rotate together with the rotatable member around the rotation axis. The x-ray tube further includes an electron beam generator configured to generate at least one electron beam. The at least one electron beam is directed to bombard the helical fin as the helical fin rotates, producing x-rays whose focal spot moves in space along a line defined by the at least one electron beam.

Abstract: Embodiments of the present disclosure pertain to methods of separating nucleic acids from a sample by applying the sample to a fiber-based electrophoresis medium and generating an electric field across the fiber-based electrophoresis medium, where the generated electric field induces migration and separation of the nucleic acids across the fiber-based electrophoresis medium. The methods of the present disclosure may also include a step of detecting one or more of the separated nucleic acids on the fiber-based electrophoresis medium, diagnosing a disease or condition based on the detecting, and implementing a treatment decision based on the diagnosis. Additional embodiments of the present disclosure pertain to nucleic acid separation systems for separating nucleic acids and methods of making them.

Abstract: A method for task processing, an electronic apparatus and a storage medium are provided. The method includes: determining a first computing density level for processing one task or a plurality of tasks; gradually increasing a computing density of a computing unit for processing the one task or the plurality of tasks to the first computing density level within a first time period before processing the one task or the plurality of tasks; processing the one task or the plurality of tasks by the computing unit; and gradually reducing the computing density of the computing unit to a second computing density level within a second time period after completion of processing the one task or the plurality of tasks.

Abstract: An electronic device may include an integrated circuit, for instance a semiconductor die. The electronic device may include a substrate having a first layer and a second layer. The first and second layers may include interconnects recessed below a surface of the substrate. The substrate may include a passivation layer directly coupled with portions of the interconnects. A solder resist material may at least partially cover portions of the passivation layer directly coupled with the first interconnect surface.

Abstract: The present invention is directed to genome editing systems, reagents and methods for the treatment of hemoglobinopathies.

Abstract: Wave power generation device and sea farm are provided. The wave power generation device includes a flexible mat, a transmission module and an energy conversion module. The flexible mat has at least three vertices, and can be spread by outward tensional forces applied on the vertices. At least one of the vertices is connected with the transmission module. The energy conversion module is connected to the transmission module, to partially convert mechanical energy of the flexible mat produced under an action of wave surge into electrical energy. The flexible mat and the transmission module are cooperated to enable the flexible mat to be sufficiently spread to absorb the wave energy under the action of wave undulation of various frequencies and directions.