Abstract: A snack product includes legume, deactivated transglutaminase (TG), oil, moisture, and/or seasonings. The legume dough used to make the snack product includes transglutaminase (TG) to form a modified dough having improved sheetability characteristics as compared to a similar dough without TG. The legume dough may include from about 60 wt. % to about 100 wt. % legumes. An exemplary method of making the modified legume dough includes adding about 0.5 wt. % to about 5 wt. % TG, incubating the modified legume dough at about 100° F. to about 140° F. for between about 5 minutes to about 120 minutes.

Abstract: A snack product includes legume, deactivated transglutaminase (TG) oil, moisture, and/or seasonings. The legume dough used to make the snack product is modified to include transglutaminase (TG) to increase its sheetability. The legume dough may include from about 60 wt. % to about 100 wt. % legumes. An exemplary method of making the modified legume dough includes adding about 0.5 wt. % to about 5 wt. % TG, incubating the modified legume dough at about 100° F. to about 130° F. for between about 5 minutes to about 120 minutes.

Abstract: The application provides guidance and navigation control (GNC) proteins. In one embodiment, the GNC protein Comprises a T-cell binding moiety and a cancer-targeting moiety, wherein the T-cell binding moiety has a binding specificity to a T-cell receptor comprising CD3, CD28, PDL1, PD1, OX40, 4-1BB, GITR, TIGIT, TIM-3, LAG-3, CTLA4, CD40, VISTA, ICOS, BTLA, Light, NKp30, CD28H, CD27, CD226, CD96, CD112R, A2AR, CD160, CD244, CECAM1, CD200R, TNFRSF25 (DR3), or a combination thereof, and wherein the cancer targeting moiety has a binding specificity to a cancer cell receptor.

Abstract: A method for backup protection in an electrical switchgear. Electrical voltage and/or current values of the switchgear are used to check whether, in a first protective switching device of the switchgear, a switching arc burns for longer than a predetermined period of time. If this is the case, a second protective switching device, which is arranged upstream of the first protective switching device, is caused to trigger.

Abstract: An antibody targeting human Trop2 simultaneously is coupled to a camptothecin drug to form an antibody-drug conjugate with stable treatment and excellent uniformity, and the drug-to-antibody ratio (DAR) is 6.0-8.0. The antibody-drug conjugate has a structure shown in general formula I, wherein Ab refers to an antibody targeting Trop simultaneously, which is coupled to a linker-camptothecin drug. In addition, also disclosed are a preparation and purification method for the antibody-drug conjugate, and an application in tumor treatment. Further, also disclosed is a linker-drug compound that can be coupled to Ab to form an antibody-drug conjugate.

Abstract: A method protects against fault arcs in an electric power distribution system in which electric power from an electric feed point is distributed via a common superordinate main distribution line and from the common main distribution line via multiple subordinate output lines. The main distribution line can be interrupted by a main switch, and each of the output lines can be interrupted by a paired output switch. A fault arc current threshold which, when exceeded by a fault arc current of a fault arc, is a precondition for triggering the main switch is matched to the maximum forward current and/or the output trigger duration of the output switches such that a fault arc is quenched selectively either by one of the output switches or by the main switch before the energy released by the fault arc exceeds a specified energy threshold.

Abstract: A method for protecting against fault arcs in an electric power distribution system in which electric power from an electric power source is distributed via a common superordinate main distribution line and from the common main distribution line via multiple subordinate output lines. The main distribution line can be interrupted by a main switch, and each of the output lines can be interrupted by a paired output switch. When a fault arc is detected in the power distribution network based on electric voltage and/or current values in the main distribution line, a decision of whether to trigger a quenching process of the fault arc of the main switch or one of the output switches is made on the basis of voltage and/or current values in the output lines.

Abstract: A method includes the low-complexity ascertainment of process-related energy consumption information for a plurality of automated processes based on measurement data which have been recorded for all of the processes. The energy consumption profile of the plurality of processes is matched to sequence information of the individual processes and changes in the energy consumption of the plurality of processes are assigned to the individual processes based on the sequence information thereof. Energy consumption information for the individual processes is then determined based on changes in the energy consumption of the plurality of processes assigned to the respective processes. A device, a system, a computer program and a computer program product are also provided.

Abstract: This document relates to methods and materials for assessing and/or using one or more senotherapeutic agents. In some cases, methods and materials for determining the efficacy of an anti-senescence treatment in a mammal (e.g., a human) are provided. For example, a level of one or more ?-Klotho polypeptides in a sample (e.g., a urine sample) from a mammal (e.g., a human) can be used to determine the efficacy of the one or more senotherapeutic agents. In some cases, methods and materials for treating a mammal (e.g., a human) having a disease or disorder characterized by a reduced level of an ?-Klotho polypeptide are provided. For example, one or more senotherapeutic agents and/or one or more inhibitors of a senescence-associated secretory phenotype (SASP) polypeptide can be administered to a mammal (e.g., a human) to increase a level of ?-Klotho polypeptides within the mammal.

Abstract: A redundant power supply is provided having a first power supply, which is connectable to a busbar by a first tie switch and is disconnectably connected to a first load by a first line system, and having a second power supply, which is connectable to the busbar by a second tie switch and is disconnectably connected to the first load by a second line system, and having a third power supply, which is connectable to the busbar by a third tie switch and is disconnectably connected to a second load by a third line system, and having a fourth power supply, which is connectable to the busbar by a fourth tie switch and is disconnectably connected to the second load by a fourth line system. All of the tie switches are open during trouble-free operation.

Abstract: A fruit sorting apparatus and method are provided. The fruit sorting apparatus includes: a control unit, a conveying assembly, a detection assembly, fruit cups, a plurality of fixing assemblies and a plurality of detection units, wherein the control unit is configured to receive a plurality of pieces of detection information, and match detection information corresponding to a fruit cup of the in-place signal according to a running speed of the conveying assembly, a starting point time of an in-place signal, the distance between the detection unit and the detection assembly and time information of the detection information.

Abstract: A bispecific antibody simultaneously targeting two different epitopes or targets is coupled with a camptothecin drug to form a bispecific antibody-toxin conjugate that is stable in treatment and excellent in uniformity, and a drug-to-antibody ratio (DAR) thereof is 6.0-8.0. The antibody-toxin conjugate has a structure as represented by general formula (I), wherein Ab represents the bispecific antibody simultaneously targeting two different epitopes or targets, which is coupled with a linker-camptothecin drug. In addition, the present invention further relates to a preparation and purification method for the antibody-toxin conjugate, and an application thereof in tumor treatment. Furthermore, the present invention further relates to a linker-drug compound capable of being coupled with Ab to form the antibody-toxin conjugate.

Abstract: Disclosed is a non-natural amatoxin-type antibody conjugate, said conjugate similar to the natural amatoxin is linked to a biopharmaceutically acceptable salt with a target biomolecule so as to obtain stability in blood plasma, and efficiently kill tumor cells in cells.

Abstract: An electrical network is equipped with feed-in devices, loads, a distribution grid arranged therebetween, at least one semiconductor switch, and at least one electromechanical switch for separating a feed-in device or a load in the event of a fault. The feed-in devices and loads are arranged in groups which are connected together by a busbar and paired semiconductor switches. Each feed-in device and load can be separated from the grid by an electromechanical switch in the event of a fault, and the individual groups of feed-in devices and loads can be separated from one another by the semiconductor switches in the event of a fault in order to prevent cross currents on the busbar.

Abstract: A computer-implemented method in a processing device of an Optical Critical Dimension (OCD) metrology system includes receiving grating parameters as input to a neural network. The neural network generates an output including a predicted optical response of a grating based on the grating parameters. Responsive to determining that a difference between the predicted optical response and a measured optical response of the grating is within a specified threshold, the grating parameters are output as a predicted structure of the grating. Responsive to determining that the difference is greater than the specified threshold, the grating parameters received as input to the neural network are iteratively updated until the predicted optical response and the measured optical response converge.

Abstract: Embodiments of the present disclosure disclose a three-dimensional path display method, device, computer-readable storage medium, electronic apparatus and computer program product. Therein the method comprises: determining, from a target three-dimensional space, a first sampling-point set comprising points; based on the first sampling-point set, generating a curve indicating the three-dimensional path to be generated; based on the curve, generating the three-dimensional path comprising a path region set, wherein the three-dimensional path passes through the points of the first sampling-point set; determining a mapping relationship between vertices of respective path regions in the path region set and pixels in a preset two-dimensional picture; according to the mapping relationship, inserting corresponding pixels into path regions in the path region set; and displaying the three-dimensional path after the pixels are inserted.

Abstract: A fruit and vegetable sorting and conveying device includes a roller assembly, a support bracket and a base. The roller assembly is positioned on the support bracket. The support bracket is movably connected to the base. The support bracket and the roller assembly are cooperatively configured to carry fruit and vegetable. The roller assembly is also configured to make the fruit and vegetable rotate. The support bracket includes a support portion and two mounting arms. Two ends of the support portion are connected to the two mounting arms respectively. The roller assembly is positioned between the two mounting arms. Each mounting arm includes an avoidance step. The avoidance step is configured to allow a strip brush to extend thereinto to reduce a relative distance between an end of the strip brush and an axis of the roller assembly.

Abstract: Systems and methods for generating a remodeling plan for a property are disclosed. An exemplary system includes a communication interface configured to receive a floor plan of the property and a remodeling preference. The system further includes at least one processor configured to obtain structural data of the property based on the floor plan and obtain a neural network model based on the remodeling preference. The neural network model is trained using sample floor plans and sample remodeling data for the remodeling preference. The at least one processor is further configured to learn structural remodeling information based on the floor plan and the structural data using the neural network model. The at least one processor is also configured to generate the remodeling plan for the property based on the structural remodeling information. The remodeling plan identifies one or more structures in the floor plan for remodeling.

Abstract: Disclosed are systems and methods for determining a concentration of a plant ingredient in a developed food product before or while making the food product. A method may include: receiving, by a computing system, protein data for the plant ingredient, retrieving at least one model trained to generate output indicating a desired concentration of the plant ingredient to be used in developing the food product, the model including at least one of a pH, temperature, and protein-content model, providing the received protein data as input to the model, receiving the output from the model, and generating instructions for developing the food product including the desired concentration range of the plant ingredient.

Abstract: In a method for coordinating a distribution grid of different levels of electromechanical switches and automatically electrically closable apparatuses in a DC circuit, the distribution grid is arranged between feed-in devices and loads and includes at least one busbar. Each of the apparatuses includes an electrical switch to open or close the DC circuit, a fault current detection device, a tripping unit, and a pre-charging apparatus.