Abstract: Compounds active on protein kinases are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: The present disclosure relates to the field of computer vision image dehazing and discloses a single image dehazing method based on detail recovery. The method includes step 1: constructing a training dataset; step 2: constructing a backbone dehazing network to achieve preliminary image dehazing: based on the U-Net network model, introduce a residual module based on pixel attention mechanism in the encoding region, and an feature enhancement module in the decoding area; step 3: constructing a detail recovery network for image detail recovery, and introducing residual shrinkage module and spatial attention mechanism; step 4: training an overall network model composed of the backbone dehazing network and the detail recovery network; step 5: Testing. The present disclosure can effectively remove fog while improving the problem of edge detail information loss, reducing the blurring of the edges of the dehazing image, and generating a higher-quality dehazing image.

Abstract: A display module is provided, including a display panel and a flexible printed circuit (FPC) bonded to the display panel; the display panel includes a display area and a non-display area disposed at the periphery of the display area, the non-display area includes a bonding area disposed on one side of the display area, and a driver integrated circuit (IC) is disposed in the bonding area; the FPC includes a main body part, an orthographic projection of the main body part onto the display panel is in the bonding area, and a first accommodating groove for accommodating the driver IC is provided in a first surface of the FPC close to the display panel; a heat dissipation structure extending from within the first accommodating groove to outside the FPC is further disposed between the FPC and the bonding area. A display device is further provided.

Abstract: The present invention pertains to the technical field of aeromagnetic survey, and specifically pertains to a storage device for a data analyzer for acrospace magnetic field measurement, which comprises a storage box body, a moving structure for facilitating movement is connected to the storage box body, a shielding structure for shielding sunlight is connected to the storage box body, an accommodating structure for accommodating an article is connected to the storage box body, a support structure for supporting is connected to the accommodating structure, and a placing structure for placing is connected to the storage box body.

Abstract: A method, system, and computer program product that are configured to: receive a Structured Query Language (SQL) statement including placeholders; generate sets of predicted values for the placeholders; generate candidate access paths in a database using the sets of predicted values; receive a query including the SQL statement with actual values instead of the placeholders; select one of the candidate access paths based on determining similarities of the actual values to ones of the sets of predicted values; in response to the selected one of the candidate access paths being acceptable, execute the query using the selected one of the candidate access paths; and in response to the selected one of the candidate access paths not being acceptable, generate a new access path in the database using the actual values, and execute the query using the new access path.

Abstract: A display system and a power-saving method thereof are provided. In a first standby mode, a control circuit of a display device detects whether a preset pin of a signal input port generates a voltage variation or maintains at a preset voltage value during a preset period. When the control circuit detects the voltage variation or the preset voltage value, the control circuit switches the display device to a second standby mode and generates an output signal according to an input signal received by the signal input port, and allows the output signal to be transmitted to the signal output port, or establishes a network connection according to the input signal. When the control circuit does not detect the voltage variation nor the preset voltage, the first standby mode is maintained by the control circuit.

Abstract: This disclosure describes systems. methods. and devices related to deep learning-based video processing. A system may include a first neural network associated with generating kernel weights for the DL VP. the first neural network using a first hardware device: and a second neural network associated with filtering image pixels for the DLVP. the second neural network using a second hardware device, wherein the first neural network receives image data and generates the kernel weights based on the image data, and wherein the second neural network receives the image data and the kernel weights. and generates filtered image data based on the image data and the kernel weights.

Abstract: The present disclosure provides an image-quality calibrating method and system and a storage medium. The method includes: when a display screen is displaying a testing image, measuring the actually measured chromaticity coordinate of a target pixel unit in the image; according to a magnitude relation between the actually measured chromaticity coordinate and a standard chromaticity coordinate, by adjusting the pixel component of the target pixel unit, performing coarse adjustment to coordinate values of the actually measured chromaticity coordinate in a first direction and a second direction, and repeatedly performing the coarse adjustment till both of differences in the first direction and the second direction between the actually measured chromaticity coordinate obtained after the coarse adjustment and the standard chromaticity coordinate are less than a first preset value.

Abstract: Phase separated articles that include a matrix phase including an acrylate copolymer; and a silicone elastomer phase stably dispersed in the matrix phase are described. The matrix phase may be derived from precursors comprising from 60 to 95 parts by weight of an alkyl acrylate having an alkyl group having 1 to 14 carbon atoms. Methods of forming phase separated articles, and articles including phase separated articles are also described.

Abstract: An enterovirus multi-antigen epitope fusion protein, a gene, a vaccine and a preparation method thereof are provided, relating to the field of vaccine preparation technologies. The amino acid sequence of the enterovirus multi-antigen epitope fusion protein is shown in SEQ ID NO: 4. The vaccine is prepared by adopting the preparation method of a genetically engineered protein vaccine, and the prepared vaccine has stronger specificity. After protein purification, there are fewer impure proteins and more specific antigen proteins, thus improving the effectiveness and safety of the combined vaccine.

Abstract: A dataset is determined to include skewed data and based on determining that the dataset includes skewed data, one or more sparse indexes for the skewed data of the dataset are built. A sparse index of the one or more sparse indexes is for a range of data of the skewed data, and the building the sparse index includes indicating one pointer for a selected record of the range of data and indicating another pointer for another selected record of the range of data. The sparse index is provided to be used in a query of the dataset.

Abstract: Performing predictive analysis on running batch jobs is provided. A series of batch end time predictive models is retrieved according to a sequence of milestone jobs in a batch of jobs. Retrieved batch end time predictive models are assembled into an aggregate batch end time predictive model to increase accuracy and stability of an end time prediction of the batch of jobs. The aggregate batch end time predictive model is utilized to predict an end time of the batch of jobs during running of the batch of jobs to form a predicted end time of the batch of jobs.

Abstract: A computer implemented method manages an ensemble model system to classify records. A number of processor units cluster records into groups of records based on classification predictions generated by base models in the ensemble model system for the records. The number of processor units determines sets of weights for the base models that increase a probability that the base models in the ensemble model system correctly predict the groups of records. Each set of weights in the sets of weights is associated with a group of records in the groups of records.

Abstract: Provided are compositions and methods useful for inserting a larger nucleic acid fragment to a target genome sequence. The editing system employs a pair of pegRNA which, by virtue of their targeting nearby genomic sites and having sequences complementary to each other, collectively form a template for inserting a large exogenous sequence to the target genomic locus.

Abstract: The present invention discloses a clustering routing optimization method based on adaptive evolutionary algorithm for a wireless sensor network, comprising following steps: performing population initialization by initial position and energy information of sensor nodes; calculating fitness values, and implementing iterative operation of elite preservation, adaptive crossover and mutation; after the iteration, selecting a cluster head; routing data packet of the cluster head to a base station. Convergence process of the evolutionary algorithm is improved by nonlinearly adjusting the probability of crossover and mutation; upper and lower bound of crossover and mutation operators are dynamically adjusted by fitness value; adding an incentive factor, adjusting the crossover and mutation probability when the fitness value tends to converge, and running the algorithm again to confirm that a new optimal value is generated.

Abstract: A fixture for testing bending shifting of a flexible display module and a test method thereof are provided. The flexible display module includes a bending region and a first non-bending region and a second non-bending region located at two sides of the bending region, the flexible display module is bent through the bending region, and the first non-bending region or the second non-bending region has an under-screen opening; the fixture includes a first support plate and a second support plate rotatably connected, the first support plate is configured to be fixedly connected with the first non-bending region, and the second support plate is configured to be fixedly connected with the second non-bending region; the first support plate or the second support plate has a transparent region, and the transparent region is disposed for observation of shifting at the under-screen opening of the flexible display module in a bent state.

Abstract: A power supply circuit, a driving method thereof, a printed circuit board, a display module and a display apparatus are disclosed, which relates to a technical field of displaying. The power supply circuit includes a first power management chip and a second power management chip configured to be respectively connected with a display panel and provide different driving signals to the display panel, and the driving signals are configured for driving the display panel to display.

Abstract: The present disclosure describes compositions and methods for treating cancers such as acute myeloid leukemia (AML), in particular relapsed and refractory AML. The method entails administering to the patient an antibody or a chimeric antigen receptor (CAR)-expressing immune cell targeting a molecule such as CD33, CD123, CD117 or CLL-1 following, or concurrently with, transplanting to the patient an engineered stem cell expressing the same molecule but with a mutation disrupting the epitope to the antibody or CAR. Due to the mutation, the engineered stem cell, unlike endogenous hematopoietic cells, is not targeted by the therapy and thus can supply the patient with functional hematopoietic cells and antigens.

Abstract: Polymer composite materials and methods of preparation are discussed. The composite material may comprise a polyurethane foam and a plurality of inorganic particles dispersed in the polyurethane foam. The composite material may have moisture movement properties, such that (a) a sample of the composite material having a length of 48 inches has a moisture movement of less than 0.15% along the length, and/or (b) a sample having a length of 6 inches has a moisture movement of less than 0.8% along the length, when submerged in 45° C. distilled water for 14 days.

Abstract: A storage device is provided. The storage device includes a control unit, a hot spare area, and a data area. Because a quantity of bits that can be stored in a second-level storage unit corresponding to the hot spare area is less than a quantity of bits that can be stored in a first-level storage unit corresponding to the data area, data read/write performance of the hot spare area is higher than data read/write performance of the data area. In a data access process, the storage device temporarily stores target data in the hot spare area, and a data read/write speed of the storage device is consistent with a data read/write speed of the hot spare area. This improves data access efficiency of the storage device.