Abstract: A method of preparing a nonwoven web that has substantially continuous synthetic fine fiber includes preparing an aqueous amide crosslinked polymer solution. The solution is extruded through a die having a plurality of orifices to form a plurality of threadlines. The threadlines are then attenuated with a primary gaseous source under conditions sufficient to permit the viscosity of each threadline to increase incrementally with increasing distance from the die, at a rate sufficient to provide fibers having a desired attenuation and mean fiber diameter without significant fiber breakage.

Abstract: Benzamide compounds of Formula VII are prepared by reacting a benzoate compound of Formula V with an amine to obtain a benzamide compound of Formula VI, and then treating the benzamide VI with an amine deprotecting agent to obtain the benzamide VII; wherein R1 and R2 are each independently H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, or substituted aryl; R3 is alkyl, -alkylaryl, or aryl; and P* is an amino protective group.

Abstract: Methods of making permanently wettable superabsorbent material are provided. The permanently wettable superabsorbent materials made by the method have a floating time less than 30 seconds and cause a reduction in surface tension of saline less than about 30%. The methods involve treating the superabsorbent material with a surfactant solution. A surfactant is used that has at least one functional group that is reactive with the superabsorbent material and at least one non-reactive and hydrophilic functional group. The surfactant is applied to the superabsorbent material when the functional groups on the surface of the superabsorbent material are activated. Permanently wettable superabsorbent materials, such as fibers, made by the method and disposable absorbent products comprising the permanently wettable superabsorbent material are also provided.

Abstract: The preparation of sultams is disclosed. In one embodiment (e.g. scheme (I)), an alkanesulfonyl halide is reacted with a haloalkylamine to obtain the corresponding N-(haloalkyl)alkanesulfonamide which is then cyclized in the presence of a deprotonating agent to give the sultam. The sultams are useful as intermediates in the preparation of naphthyridine carboxamide compounds which are HIV integrase inhibitors.

Abstract: A container inspection equipment with cobalt-60 &ggr;-ray source and cesium iodide or cadmium tungstate detector includes a cobalt-60 &ggr;-ray source, a cask, a front collimator, a rear collimator, a cesium iodide or cadmium tungstate detector, signal and image processing systems, container trailer system, and automatic control system. The cask of the cobalt-60 &ggr;-ray source, the beam shutter, and the front collimator are fixed on the same chassis to form an integration and placed in the source room. The rear collimator, cesium iodide or cadmium tungstate array detector and the radiation catcher are fixed on the same chassis to form an integration and placed in the detector room. A container inspection tunnel is formed between the source room and the detector room. The equipment is mainly used for inspecting smuggling goods and contrabands etc., in large containers, container trucks, train carriage and air containers.

Abstract: The present invention provides new trans-9,10-dehydroepothilone C and trans-9,10-dehydroepothilone D based derivative compounds, compositions and methods of inhibiting cellular hyperproliferation and/or stabilizing microtubules in vitro and of treatment of hyperproliferative diseases in vivo. Also disclosed are methods of making the compounds.

Abstract: A system and process for creating custom fit artificial fingernails using a non-contact measuring device is disclosed. A fingernail is measured for its topographical configuration by an optical non-contact measuring device. The measured topography of the fingernail is then used to direct a machining device to create an artificial fingernail. Also disclosed is a method to digitally design an artificial fingernail, which has a portion of its under surface fitted to the natural fingernail by using a special computer program. The three-dimensional shape information of the digitally designed artificial fingernail is then converted into machine codes to drive a computer numerical controllable device, which will then cut the artificial fingernail from a piece of raw material. Finally, the user selected nail art can be printed onto the artificial fingernail by using a nail art printing device.

Abstract: A motor drive system control provides global closed loop feedback to cooperatively operate system components to adaptively reduce noise and provide noise cancellation feedback. An active EMI filter reduces differential and common mode noise on an input and provides a noise level indication to a system controller. Power switches in both a power converter and power inverter are cooperatively controlled with dynamic dv/dt control to reduce switching noise according to a profile specified by the controller. The dv/dt control is provided as an analog signal to a high voltage IC and codified as a pulse width for a level shifting circuit supplying control signals to the high voltage gate drive. A noise extraction circuit and technique obtain fast noise sampling to permit noise cancellation and adaptive noise reduction.

Abstract: The present invention relates to a micro-array system and the uses thereof. Particularly, the micro-array system is for a micro amount of biomolecules carrying on a bioreaction in a reaction solution, which comprises a substrate comprising a plurality of micro-wells for receiving the reaction solution; a plurality of micro-beads placing in the reaction solution for the biomolecules attached on surfaces thereon; and a vibrating module for vibrating the substrate, which makes the biomolecules attached on the micro-beads react evenly. Optionally, the micro-array system further comprises a temperature control module for controlling the temperature of the reaction solution. The bioreaction performed in the micro-array system according to the invention has the advantages of having a high sensitivity, being easily post-manipulated, being easily operated, having a high reliability and being reusable.

Abstract: A power inverter control adjusts input power to track with output power to reduce energy handling requirements for an inverter DC bus. Input power to the power inverter circuit is measured and compared with a measurement of inverter output power. The comparison result is applied to a power factor correction circuit to adjust input power to track with output power, while obtaining a good power factor for the power inverter circuit. The energy requirements and ripple voltages or ripple currents on the DC bus are reduced, leading to a reduction in rating specifications for passive energy storage elements on the DC bus.

Abstract: Absorbent article including an absorbent core having multiple absorbent layers. The absorbent layers interact in a manner which desirably locates absorbed liquid in an appointed, high saturation wicking layer.

Abstract: An absorbent fibrous foam composite comprising a fluid intake capacity of at least 15 g/g, a vertical wicking distance of at least 10 cm, and an absorbency under zero load of at least 15 g/g. The absorbent fibrous foam composite comprising a water insoluble fibrous material and a superabsorbent material. The absorbent fibrous foam composite made by forming a slurry of water, a water-insoluble fiber, and a binding agent. A water-swellable, water-insoluble superabsorbent material is added to the slurry and the temperature is lowered until the water freezes. The frozen water is then removed by sublimation process and an absorbent fibrous foam recovered. The Gelation Time, which represents a fluid absorption rate of superabsorbent during the preparation, is critical to preparing uniform absorbent freeze-dried foams and can be adjusted by various mixing conditions and physical and chemical superabsorbent treatments.

Abstract: A nonwoven web and method of preparing a novel nonwoven web of synthetic fiber are disclosed. An aqueous solution amide crosslinked synthetic precursor polymer is extruded under defined conditions through a plurality of die orifices to form a plurality of threadlines. The threadlines are attenuated with a defined primary gaseous source to form fiber under conditions of controlled macro scale turbulence and under conditions sufficient to permit the viscosity of each threadline, as it leaves a die orifice and for a distance of no more than about 8 cm, to increase incrementally with increasing distance from the die, while substantially maintaining uniformity of viscosity in the radial direction, at a rate sufficient to provide fiber having the desired attenuation and mean fiber diameter without significant fiber breakage. The attenuated threadlines are dried with a defined secondary gaseous source. The resulting fibers are deposited randomly on a moving foraminous surface to form a substantially uniform web.

Abstract: Absorbent structures that form superabsorbent polymers in situ. The structures include an absorbent material and a fibrous material containing an activating agent. The fibrous material releases the activating agent upon stimulation with an activator, which causes the polymer to become a superabsorbent polymer. The absorbent component is desirably a water-swellable, water-insoluble polymer. The absorbent structures form a superabsorbent composition in situ. Methods of making the activating agent containing fibrous material are provided.

Abstract: Disclosed is a fibrous absorbent structure that is wet stable and has large void volume with a density below the critical density of the fiber employed. In one embodiment, the fibrous absorbent uses open-celled foam technologies to keep the fibrous structure expanded and bonded. In other embodiments, the resulting fibrous structure resembles an open-celled polymeric foam, with fibers serving as struts stabilized by binder material. In another embodiment, the resulting fibrous structure is filled with hydrophilic open-celled foams with the cell size substantially smaller than the fibrous pores. Such a wet-stable, high void volume fibrous absorbent can be used in a disposable product intended for the absorption of fluid such as body fluid, including extensible absorbent articles.

Abstract: Methods for the identification of a drug target, wherein the drug target is a component of a signal transduction pathway, are provided. The methods are based, in part, on selection of a gene of therapeutic interest and determination of regulatory DNA sequences which regulate expression of the gene in a cell of interest, followed by reconstruction of signal transduction pathways which act on molecules which bind to the regulatory sequence. Also provided are methods for assessing potential pharmacological effects and/or side effects of an agent, based on the effect of the agent on the distribution and properties of accessible regions in cellular chromatin.

Abstract: Techniques are provided for use in establishing and maintaining a contacting/communication service and/or network that does not necessarily require the use of dedicated server devices. For example, improved methods and apparatuses are provided that can be used to provide peer-to-peer (P2P) or other like forms of communication in such a manner that users can remain aware of others' online/offline statuses, search for other users, conduct audio/video talk and chat with others, exchange information, and/or communicate in other ways with one another.

Abstract: A nonwoven web and method of preparing a novel nonwoven web of synthetic fiber are disclosed. An aqueous solution amide crosslinked synthetic precursor polymer is extruded under defined conditions through a plurality of die orifices to form a plurality of threadlines. The threadlines are attenuated with a defined primary gaseous source to form fiber under conditions of controlled macro scale turbulence and under conditions sufficient to permit the viscosity of each threadline, as it leaves a die orifice and for a distance of no more than about 8 cm, to increase incrementally with increasing distance from the die, while substantially maintaining uniformity of viscosity in the radial direction, at a rate sufficient to provide fiber having the desired attenuation and mean fiber diameter without significant fiber breakage. The attenuated threadlines are dried with a defined secondary gaseous source. The resulting fibers are deposited randomly on a moving foraminous surface to form a substantially uniform web.

Abstract: Methods for the identification of a drug target, wherein the drug target is a component of a signal transduction pathway, are provided. The methods are based, in part, on selection of a gene of therapeutic interest and determination of regulatory DNA sequences which regulate expression of the gene in a cell of interest, followed by reconstruction of signal transduction pathways which act on molecules which bind to the regulatory sequence. Also provided are methods for assessing potential pharmacological effects and/or side effects of an agent, based on the effect of the agent on the distribution and properties of accessible regions in cellular chromatin.

Abstract: An absorbent article (10) includes a backsheet layer (30), a liquid permeable topsheet layer (28), and an absorbent body (32) sandwiched between the backsheet and topsheet layers. The absorbent body (32) includes a first fibrous stratum (52) having a first quantity of absorbent fibers, a second fibrous stratum (54) having a second quantity of absorbent fibers, and at least a third fibrous stratum (56) which is located between and integrally formed with the first and second fibrous strata (52, 54). In particular aspects, the third fibrous stratum (56) includes an operative quantity of a substantially hydrophilic, wet-strength agent. In other aspects, the wet-strength agent is distributed in the third quantity of absorbent fibers to render the third fibrous stratum (56) substantially non-dispersible.