Abstract: The present invention provides a liquid crystal panel and a manufacture method thereof. The liquid crystal panel comprises: a first substrate (1), a TFT layer (2) located on the first substrate (1), a color resist layer (3) located on the TFT layer (2), a photospacer layer (4) located on the color resist layer (3), a protective layer (5) located on the color resist layer (3) and the photospacer layer (4), a via hole (6) penetrating the color resist layer (3) and the protective layer (5), a pixel electrode layer (7) formed on the protective layer (5) and electrically connected to the TFT layer (2) with the via hole (6) and a second substrate (8) oppositely located to the first substrate (1), and one or more color resist material in the photospacer layer (4) and the color resist layer (3) are the same, and the photospacer layer (4) and the color resist layer (3) are formed at the same time during a manufacture process.

Abstract: A dynamic braking system for an electric power system includes a switching device coupled to an electrical conductor. The switching device is configured to open and close with a plurality of predetermined frequencies. The dynamic braking system also includes an inductive device coupled to the switching device. The power losses of the inductive device are at least partially a function of the plurality of predetermined frequencies. The dynamic braking system further includes a dynamic braking controller coupled to the switching device. The dynamic braking controller is configured to open and close the switching device with at least one of the predetermined frequencies to dissipate electric power from the electrical conductor at a predetermined rate by regulating the power losses of the inductive device as a function of the predetermined frequencies.

Abstract: A chassis includes a shell, two sliding rails, a slider and a bracket. The two sliding rails are fixed to the shell. The slider is slidably fixed to one of the two sliding rails. The slider includes a positioning post. The bracket defines a groove. The positioning post is located in the groove and moves from a first position to a second position along the groove. When the positioning post is located at the first position, the bracket is locked with the shell. When the positioning post is located at the second position, the bracket is unlocked from the shell and can move away relative to the shell.

Abstract: A method and apparatus for accessing a wireless sensor network are provided in embodiments of this invention. The technical solution provided in embodiments of this invention includes: when receiving a first beacon frame, stopping channel scan temporarily, and establishing a new channel scan sequence according to operating channels of a current wireless sensor network recorded in the beacon frame. Non-operating channels are not included in the new channel scan sequence. Time for performing subsequence channel scan is reduced, so that the process of accessing the current wireless sensor network of a device node expecting for network can be accelerated.

Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

Abstract: A method and an apparatus are provided. The apparatus is a hardware module that controls a power mode of a plurality of modules. The apparatus receives an indication of a desired operational frequency. Based on the received indication, the apparatus determines to switch from a first power mode associated with a first set of modules to a second power mode corresponding to the desired operational frequency and associated with a second set of modules. The apparatus enables modules in the second set of modules that are unassociated with the first power mode, stops traffic through the plurality of modules upon expiration of a time period after enabling the modules in the second set of modules that are unassociated with the first power mode, routes traffic through the second set of modules, and disables modules in the first set of modules that are unassociated with the second power mode.

Abstract: Embodiment of present disclosure provides a method for preparing ceritinib of formula I, comprising: (1) contacting a compound of formula 12b with an amino protective group to obtain a compound of formula 3; (2) contacting the compound of formula 3 with a compound of formula 9a to obtain a compound of formula 5; and (3) subjecting the compound of formula 5 to a deprotection reaction to obtain the ceritinib of formula I. Then ceritinib may be effectively prepared.

Abstract: A method for preparing BTK inhibitor CC-292 of formula 1, comprising: (1) contacting a compound of formula 2 with a compound of formula 3 to obtain a compound of formula 4; (2) contacting the compound of formula 4 with a compound of formula 5 to obtain a compound of formula 6; (3) contacting the compound of formula 6 with trifluoromethanesulfonic anhydride to obtain a compound of formula 7; and (4) contacting the compound of formula 7 with a compound of formula 8 to obtain the compound of formula 1,

Abstract: A method of making a flexible, foldable, stretchable electronic device. The method includes deposition of a polymer layer, such as parylene C, to impart flexibility to the device. The device overcomes the limitations of related flexible electronics schemes by employing established silicon-on-insulator complementary metal-oxide-semiconductor technology with a flexible enclosure. Devices made in such a way may be used in a wide variety of applications including incorporation into medical devices.

Abstract: A multilevel converter comprising a first switching branch connected between a positive DC-link terminal and an AC output terminal and comprising series-connected first and second switching elements, a second switching branch connected between the AC output terminal and a negative DC-link terminal and comprising series-connected third and fourth switching elements, a third switching branch connected between a DC-link neutral point and a connection point of the first and the second switching elements, a fourth switching branch connected between the DC-link neutral point and a connection point of the third and the fourth switching elements, the fourth switching branch being completely independent from the third switching branch, and a flying capacitor connected between the connection point of the first and the second switching elements and the connection point of the third and the fourth switching elements.

Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

Abstract: A routing method and apparatus are provided. The routing method includes the following steps: sending a probe frame that carries an address of a destination node to a neighboring node(s); receiving a response message returned; selecting one neighboring node from the neighboring node(s) that returns the response message as a next-hop node to which data is sent. A neighboring node with a cost parameter which is lower than a cost parameter in a routing table of the destination node is selected as the next-hop node. In the routing method, when a routing node forwards data, the route is found in real time by broadcasting a probe frame, and data may be sent as long as any one of the neighboring nodes that may arrive at the destination node is in an active state, and thus a data transmission delay is shortened.

Abstract: A method for controlling a power generation system connected to a weak grid may generally include operating a power converter of the system so as to produce current at or above a power factor threshold associated with a power factor operating requirement for the system, detecting that a generator speed of the system has increased over a period of time, detecting that a local reference voltage for the system has decreased within the same period of time over which the generator speed has increased and adjusting the operation of the power converter to produce current at a reduced power factor below the power factor threshold so as to increase a real power output of the system.

Abstract: Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.

Abstract: An origami enabled manufacturing system. The system uses origami design principles to create functional materials, structures, devices and/or systems having an adjustable size and/or shape. An operational device can be coupled to a planar substrate shaped and sized to correspond to a desired origami shape of an origami pattern. A plurality of planar substrates can be coupled together by a plurality of connection members that corresponds to one or more crease of the origami pattern. An array of planar substrates can be formed that convert into a three dimensional structure with origami shape. The resulting three-dimensional structure provides smaller projection area, higher portability and deformability.

Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

Abstract: A cross arm for X-ray equipment. The cross arm comprises a guide on the cross arm, a tube on the guide, and a linkage device, wherein the tube is configured to move along the guide when the cross arm rotates.

Abstract: A method of making a flexible, foldable, stretchable electronic device. The method includes deposition of a polymer layer, such as parylene C, to impart flexibility to the device. The device overcomes the limitations of related flexible electronics schemes by employing established silicon-on-insulator complementary metal-oxide-semiconductor technology with a flexible enclosure. Devices made in such a way may be used in a wide variety of applications including incorporation into medical devices.

Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.