Patents by Inventor Yong Xu

Yong Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170068024
    Abstract: A color filter substrate is provided, and includes a glass substrate, a color filter layer and a planar layer. The color filter layers include three color barrier layers and two light-shading layers. Two of the light-shading layers overlap in light-shading regions. A manufacturing method of a color filter substrate is provided, and includes sequentially forming three color barrier layers on a glass substrate, wherein a part of one of a first color barrier layer or a second color barrier layer forms a first light-shading layer, and a part of a third color barrier layer forms a second light-shading layer.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 9, 2017
    Inventor: Yong XU
  • Publication number: 20170067009
    Abstract: Cell culture devices and methods of their use are provided according to aspects of the present invention which include a base having a pair of spaced apart wells and at least one fluid port defined from an exterior of the base to each of the wells, each fluid port being spaced above the base sheet by a distance sufficient to introduce a material above a matrix deposited on the base sheet in the wells; and a cover having a pair of spaced apart well covering portions that are each disposed above a respective one of the one spaced apart wells of the base body when the cover is covering the upper surface of the base body and having a gas passage defined between the spaced apart well covering portions and at least one gas port defined from an exterior of the cover to each of the well covering portions.
    Type: Application
    Filed: September 6, 2016
    Publication date: March 9, 2017
    Inventors: Bonnie F. Sloane, Yong Xu, Kyungmin Ji, Hongen Tu, Kamiar Moin, Kingsley Osuala
  • Patent number: 9573932
    Abstract: The present disclosure provides a method for preparing a compound of formula XVII, comprising: (1) contacting a compound of formula XIV with a compound of formula 3 to obtain a compound of formula 2; and (2) contacting the compound of formula 2 with a compound of formula 4 to obtain a compound of formula XVII. The method is low toxicity, cheap, easy to get, environmentally and friendly, and is economical and industrially applicable.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: February 21, 2017
    Inventor: Yong Xu
  • Publication number: 20170029430
    Abstract: Disclosed is a series of analogues of 4H-pyrazolo[1,5-?]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.
    Type: Application
    Filed: March 30, 2015
    Publication date: February 2, 2017
    Inventors: Xuehai WANG, Zhaozhong DING, Yong XU, Shuhui CHEN, Lie LI, Gang LI, Ronghua TU, Cailin WANG, Yang YUE, Zhibo ZHANG, Hailiang CHEN, Wenjie SUN, Lu HUANG
  • Publication number: 20170028007
    Abstract: A solid dispersion containing Desmodium Styracifolium (Osb.) Merr. flavonoids, method of preparing same and use thereof. The Desmodium Styracifolium (Osb.) Merr. flavonoids are alcohol extract of Desmodium Styracifolium (Osb.) Merr., and the solid dispersion is used for preparing a drug for treating urinary tract calculi.
    Type: Application
    Filed: July 15, 2014
    Publication date: February 2, 2017
    Inventors: XUEHAI WANG, LI'E LI, YONG XU, JIE LI, RONGHUA TU, GANG CHEN, RUBIN CAO, YUN FENG, ZHONGWEN YANG, ZHAOZE FAN, YANPING YU, QIANG XIAO, LU HUANG, CHENGBING YANG, TIANCI HUANG, HUA TIAN, JING YANG
  • Publication number: 20170015631
    Abstract: Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: June 15, 2016
    Publication date: January 19, 2017
    Inventors: Koc-Kan Ho, Yong Xu, Michael David Saunders, Xiaohui Liu, Scott Albert Pearce, Kevin Bret Wright, Jason Marc Foulks, Kenneth Mark Parnell, Steven Brian Kanner, David Lee Vollmer, Jihua Liu
  • Publication number: 20170002014
    Abstract: The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.
    Type: Application
    Filed: July 11, 2016
    Publication date: January 5, 2017
    Inventors: Yong Xu, Benjamin Gary Brenning, Steven G. Kultgen, Xiaohui Liu, Michael David Saunders, Koc-Kan Ho
  • Publication number: 20160349582
    Abstract: The present invention provides a liquid crystal display panel and a color film array substrate thereof. The color film substrate comprises a substrate and a black matrix composed on the substrate, a thin film transistor array, a color filter, a pixel electrode, the pixel electrode is stacked and provided on the color filter, the thin film transistor array is stacked and provided on the black matrix as well as connected to the pixel electrode. Through the above way, the present invention does not need to provide CF open on the color filter, avoiding that the gas accommodated in the CF open leaks to the liquid crystal layer and generates bubbles, ensuring the good display effect; moreover, it can raise the encasing alignment accuracy and improve the pixel aperture ratio.
    Type: Application
    Filed: December 2, 2014
    Publication date: December 1, 2016
    Applicant: Shenzhen China Star Optoelectronics Technology Co., Ltd.
    Inventor: Yong XU
  • Patent number: 9503007
    Abstract: A method for controlling a power generation system connected to a weak grid may generally include operating a power converter of the system so as to produce current at or above a power factor threshold associated with a power factor operating requirement for the system, detecting that a generator speed of the system has increased over a period of time, detecting that a local reference voltage for the system has decreased within the same period of time over which the generator speed has increased and adjusting the operation of the power converter to produce current at a reduced power factor below the power factor threshold so as to increase a real power output of the system.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: November 22, 2016
    Assignee: General Electric Company
    Inventors: Robert Gregory Wagoner, David Smith, Yong Xu
  • Patent number: 9481665
    Abstract: The present disclosure provides a new process for preparing PI3K inhibitor buparsilib. The whole reaction route of the present invention is simple and easy to control for the industrial production.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: November 1, 2016
    Inventor: Yong Xu
  • Publication number: 20160303178
    Abstract: Disclosed are a pharmaceutical composition, a method for preparing the same and use thereof. The pharmaceutical composition consists of total flavonoids of Desmodium Styracifolium as an active ingredient and a pharmaceutically acceptable excipient. The pharmaceutical composition can be formulated in a form of a medicament formulation suitable to administration in clinic, and can be used in preparation of clinic treatment medicaments for treating dampness-heat and urinary stone (stagnation of dampness-heat).
    Type: Application
    Filed: July 15, 2014
    Publication date: October 20, 2016
    Inventors: XUEHAI WANG, JIE LI, LI'E LI, YONG XU, RONGHUA TU, GANG CHEN, RUBIN CAO, YUN FENG, ZHONGWEN YANG, ZHAOZE FAN, YANPING YU, QIANG XIAO, LU HUANG, CHENGBING YANG, TIANCI HUANG, HUA TIAN, JING YANG
  • Publication number: 20160296579
    Abstract: A capsule containing total flavonoids of Desmodium styracifolium, a method for preparing the same and a use of the capsule containing total flavonoids of Desmodium styracifolium are provided. Specifically, the capsule includes total flavonoids of Desmodium Styracifolium provided in a form of alcohol extract of Desmodium Styracifolium and a pharmaceutically acceptable excipient.
    Type: Application
    Filed: July 15, 2014
    Publication date: October 13, 2016
    Inventors: XUEHAI WANG, YONG XU, LI'E LI, JIE LI, RONGHUA TU, GANG CHEN, RUBIN CAO, YUN FENG, ZHONGWEN YANG, ZHAOZE FAN, YANPING YU, QIANG XIAO, LU HUANG, CHENGBING YANG, TIANCI HUANG, HUA TIAN, JING YANG
  • Publication number: 20160289660
    Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.
    Type: Application
    Filed: April 19, 2016
    Publication date: October 6, 2016
    Inventors: Zhenyu Zhu, Aine Quimby, Shengxi Guan, Dapeng Sun, Yishu Huang, Xuhui Lai, Siu-hong Chan, Xianghui Li, Shuang-Yong Xu, Chunhua Zhang
  • Publication number: 20160264546
    Abstract: The present disclosure provides a new process for preparing PI3K inhibitor buparsilib. The whole reaction route of the present invention is simple and easy to control for the industrial production.
    Type: Application
    Filed: March 13, 2015
    Publication date: September 15, 2016
    Inventor: YONG XU
  • Publication number: 20160257667
    Abstract: The present disclosure provides a method for preparing a compound of formula XVII, comprising: (1) contacting a compound of formula XIV with a compound of formula 3 to obtain a compound of formula 2; and (2) contacting the compound of formula 2 with a compound of formula 4 to obtain a compound of formula XVII. The method is low toxicity, cheap, easy to get, environmentally and friendly, and is economical and industrially applicable.
    Type: Application
    Filed: March 2, 2015
    Publication date: September 8, 2016
    Inventor: YONG XU
  • Patent number: 9416132
    Abstract: The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: August 16, 2016
    Assignee: Tolero Pharmaceuticals, Inc.
    Inventors: Yong Xu, Benjamin Gary Brenning, Steven G. Kultgen, Xiaohui Liu, Michael Saunders, Koc-Kan Ho
  • Patent number: 9394257
    Abstract: Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: July 19, 2016
    Assignee: Tolero Pharmaceuticals, Inc.
    Inventors: Koc-Kan Ho, Yong Xu, Michael David Saunders, Xiaohui Liu, Scott Albert Pearce, Kevin Bret Wright, Jason Marc Foulks, Kenneth Mark Parnell, Steven Brian Kanner, David Lee Vollmer, Jihua Liu
  • Publication number: 20160192285
    Abstract: A method and apparatus for accessing a wireless sensor network are provided in embodiments of this invention. The technical solution provided in embodiments of this invention includes: when receiving a first beacon frame, stopping channel scan temporarily, and establishing a new channel scan sequence according to operating channels of a current wireless sensor network recorded in the beacon frame. Non-operating channels are not included in the new channel scan sequence. Time for performing subsequence channel scan is reduced, so that the process of accessing the current wireless sensor network of a device node expecting for network can be accelerated.
    Type: Application
    Filed: March 9, 2016
    Publication date: June 30, 2016
    Inventors: Yong XU, Yongjun LIU, Mu ZHAO
  • Publication number: 20160189730
    Abstract: An example of the present invention discloses a speech separation method and a system, the method comprises: receiving a mixture speech signal to be separated; extracting a speech feature of the mixture speech signal; inputting the extracted speech feature of the mixture speech signal into a regression model for speech separation, obtaining an estimated speech feature of a target speech signal; synthesizing to obtain the target speech signal according to the estimated speech feature. Speech separation effect can be improved effectively using the present invention.
    Type: Application
    Filed: December 30, 2014
    Publication date: June 30, 2016
    Inventors: Jun DU, Yong XU, Yanhui TU, Li-Rong DAI, Zhiguo WANG, Yu HU, Qingfeng LIU
  • Publication number: 20160178959
    Abstract: A method of forming a BOA substrate includes forming an array substrate comprising a display area and a non-display area; coating a black matrix in the display area of the array substrate, and patterning the black matrix; and installing photoresist on the array substrate. The present invention also proposes a BOA substrate. The method of forming the BOA substrate enhance the quality of the BOA substrate, and further influence the display quality of LCD panels.
    Type: Application
    Filed: January 12, 2015
    Publication date: June 23, 2016
    Inventors: Yong Xu, Yuan Xiong