Abstract: Provided herein, in one aspect, are antibodies that immunospecifically bind to a human KIT antigen comprising the fourth and/or fifth extracellular Ig-like domains (that is, D4 and/or D5 domains), polynucleotides comprising nucleotide sequences encoding such antibodies, and expression vectors and host cells for producing such antibodies. The antibodies can inhibit KIT activity, such as ligand-induced receptor phosphorylation. Also provided herein are kits and pharmaceutical compositions comprising antibodies that specifically bind to a KIT antigen, as well as methods of treating or managing a KIT-mediated disorder or disease and methods of diagnosing a KIT-mediated disorder or disease using the antibodies described herein.

Abstract: Provided herein, in one aspect, are antibodies that immunospecifically bind to a human KIT antigen comprising the fourth and/or fifth extracellular Ig-like domains (that is, D4 and/or D5 domains), polynucleotides comprising nucleotide sequences encoding such antibodies, and expression vectors and host cells for producing such antibodies. The antibodies can inhibit KIT activity, such as ligand-induced receptor phosphorylation. Also provided herein are kits and pharmaceutical compositions comprising antibodies that specifically bind to a KIT antigen, as well as methods of treating or managing a KIT-mediated disorder or disease and methods of diagnosing a KIT-mediated disorder or disease using the antibodies described herein.

Abstract: An information recording and reproducing apparatus for increasing a speed of tilt control, including a portion for storing reference data, a portion for storing sample values data, a portion for obtaining positional information, a stilt servo generator, a tilt adjuster.

Abstract: A piezo electric element generates a vibrating voltage in response to a striking force on a pad. The piezo electric element is connected across a series connection of a linear resistor and a nonlinear resistance network. The voltage appearing across the nonlinear resistance network is taken as an output voltage. The nonlinear resistance network is comprised of a parallel connection of a first and a second resistance circuitry. The first resistance circuitry is a series connection of a resister and two diodes connected in parallel in an opposite polarity to each other. The second resistance circuitry is a series connection of another resister and two Zener diodes connected in series in an opposite polarity to each other.

Abstract: A piezo electric element generates a vibrating voltage in response to a striking force on a pad. The piezo electric element is connected across a series connection of a linear resistor and a nonlinear resistance network. The voltage appearing across the nonlinear resistance network is taken as an output voltage. The nonlinear resistance network is comprised of a parallel connection of a first and a second resistance circuitry. The first resistance circuitry is a series connection of a resister and two diodes connected in parallel in an opposite polarity to each other. The second resistance circuitry is a series connection of another resister and two Zener diodes connected in series in an opposite polarity to each other.

Abstract: An attachment lens is arranged in a stage subsequent to a scanning lens. After a laser beam is converged by the scanning lens, the laser beam is converted into a parallel beam by the attachment lens. When the scanning lens is displaced in a direction perpendicular to an optical axis of the laser beam, a traveling direction of the laser beam is bent by a predetermined angle immediately after the laser beam passes through the scanning lens. Then, the traveling direction of the laser beam is further bent by a predetermined angle in the same direction by the passage of the laser beam through the attachment lens. Accordingly, a final swing angle of the laser beam outgoing from an outgoing window is increased by a swing angle imparted by the attachment lens compared with the case where the attachment lens is not arranged. One of lens surfaces of the attachment lens is formed in a toroidal surface, which allows the laser beam to have a long outline in a vertical direction.

Abstract: An attachment lens is arranged in a stage subsequent to a scanning lens. After a laser beam is converged by the scanning lens, the laser beam is converted into a parallel beam by the attachment lens. When the scanning lens is displaced in a direction perpendicular to an optical axis of the laser beam, a traveling direction of the laser beam is bent by a predetermined angle immediately after the laser beam passes through the scanning lens. Then, the traveling direction of the laser beam is further bent by a predetermined angle in the same direction by the passage of the laser beam through the attachment lens. Accordingly, a final swing angle of the laser beam outgoing from an outgoing window is increased by a swing angle imparted by the attachment lens compared with the case where the attachment lens is not arranged. One of lens surfaces of the attachment lens is formed in a toroidal surface, which allows the laser beam to have a long outline in a vertical direction.

Abstract: An object of the present invention is to provide a detection device which does not cause the false detection by receiving laser light from an oncoming car. The pulse laser light modulated with a modulation pattern set every target position is irradiated at the target position from a laser irradiation portion. DSP (Digital Signal Processor) decides that there is an obstacle at the target position only when the modulation pattern of the pulse laser light emitted from the laser emitting portion matches with the modulation pattern of the pulse laser light received by the laser receiving portion. It is suppressed that the detection device misdetects the conditions of the target position when receiving laser light from an oncoming car or the like because modulation pattern of laser light from own does not match with modulation pattern of laser light from the oncoming car or the like.

Abstract: According to one embodiment, an information processing apparatus includes: a case; a device that is housed in the case; a cooling fan that cools the device; a temperature detecting device that detects a temperature of the device; and a controller that is operable in a first mode and second mode, the first mode controlling the cooling fan in a range from a stopped state to a given rotation speed in accordance with the temperature detected by the temperature detecting device, and a second mode controlling the cooling fan to rotate at a predetermined rotation speed that is lower than the given rotation speed.

Abstract: Two mirrors are placed in such a manner as to line in a Z-axis direction in a beam irradiation head. These mirrors are located at a position beyond a normal scan range of the laser light in the Z-axis direction and within a limit range of scanning of the laser light, and the angles of inclination of mirrors are adjusted so as to reflect incident laser light toward a PD. In the case where a lens is driven in a Z-axis direction (a lateral scanning direction), driving current values Ia, Ib of an actuator at the times when reflected light from these two mirrors enters the PD at the maximum light quantity are detected. A driving current Imz required to position a lens for irradiation at a neutral position and a drive amount ?zd of the lens for irradiation per a unit driving current are then determined based on the detected driving current Ia and Ib.

Abstract: One embodiment of the invention provides an information processing apparatus including: a signal generation unit that detects an open/close state of a display panel to generate a detection signal; a first determination unit that determines whether or not the open/close state of the display panel is changed based on the detection signal generated by the generation unit; a notification unit that notifies a confirmation request for confirming the status of the tablet device; an acquisition unit that acquires the status of the tablet device in response to the confirmation request by the notification unit; a second determination unit that determines whether the status of the tablet device acquired by the acquisition unit is valid or not; and a first controller that controls a function of the tablet device to be enabled or disabled based on the status of the tablet device.

Abstract: There is provided an optical disk drive capable of appropriately effecting recording and reproducing operations without being affected by offset values and a laser output value, which are set at startup of the disk drive, even when changes have arisen in the internal temperature of the disk drive because of changes in ambient temperature. In an optical disk drive, a temperature sensor provided on a pickup measures a temperature. When changes in temperature are greater than a predetermined level, a focus offset value, a tracking offset value, and a value of laser output from the pickup are reset.

Abstract: Two mirrors are placed in such a manner as to line in a Z-axis direction in a beam irradiation head. These mirrors are located at a position beyond a normal scan range of the laser light in the Z-axis direction and within a limit range of scanning of the laser light, and the angles of inclination of mirrors are adjusted so as to reflect incident laser light toward a PD. In the case where a lens is driven in a Z-axis direction (a lateral scanning direction), driving current values Ia, Ib of an actuator at the times when reflected light from these two mirrors enters the PD at the maximum light quantity are detected. A driving current Imz required to position a lens for irradiation at a neutral position and a drive amount Azd of the lens for irradiation per a unit driving current are then determined based on the detected driving current Ia and Ib.

Abstract: An attachment lens is arranged in a stage subsequent to a scanning lens. After a laser beam is converged by the scanning lens, the laser beam is converted into a parallel beam by the attachment lens. When the scanning lens is displaced in a direction perpendicular to an optical axis of the laser beam, a traveling direction of the laser beam is bent by a predetermined angle immediately after the laser beam passes through the scanning lens. Then, the traveling direction of the laser beam is further bent by a predetermined angle in the same direction by the passage of the laser beam through the attachment lens. Accordingly, a final swing angle of the laser beam outgoing from an outgoing window is increased by a swing angle imparted by the attachment lens compared with the case where the attachment lens is not arranged. One of lens surfaces of the attachment lens is formed in a toroidal surface, which allows the laser beam to have a long outline in a vertical direction.

Abstract: This invention provides a method to induce the differentiation of animal cells wherein said cells are brought into contact with cytokine only in a suitable growth phase of animal cells, and also provides a system to control the differentiation potency of animal cells wherein two or more cytokines are combined for use in the cultivation or growing of animal cells.

Abstract: According to one embodiment, an information processing apparatus includes a main body, connection ports to which external storage devices are detachably connectable, a nonvolatile memory which stores mode designation information items which correspond to the connection ports and designate whether each of the external storage devices connected to the associated connection ports is to be handled as a hard disk drive or a flexible disk drive, a drive number assignment unit which assigns, in a case where the external storage device is connected to at least one of the connection ports, one of a first drive number which designates the hard disk drive and a second drive number which designates the flexible disk drive to the external storage device, based on the mode designation information corresponding to the at least one of the connection ports.

Abstract: A method of preventing or treating neurologic function deficit of vertebrates undergone spinal cord injury, comprising administering an effective amount of BM-MNCs to a vertebrate in need thereof through cerebrospinal fluid.

Abstract: An object of the present invention is to provide a detection device which does not cause the false detection by receiving laser light from an oncoming car. The pulse laser light modulated with a modulation pattern set every target position is irradiated at the target position from a laser irradiation portion. DSP (Digital Signal Processor) decides that there is an obstacle at the target position only when the modulation pattern of the pulse laser light emitted from the laser emitting portion matches with the modulation pattern of the pulse laser light received by the laser receiving portion. It is suppressed that the detection device misdetects the conditions of the target position when receiving laser light from an oncoming car or the like because modulation pattern of laser light from own does not match with modulation pattern of laser light from the oncoming car or the like.

Abstract: A peptide has at least an amino acid sequence represented by SEQ ID NO:1 and it has an osteogenetic activity.

Abstract: A disk medium, an information recording device, and an information reproducing device are provided, which are capable of efficiently recording sub-information such as security data and, if the sub-information is set as the security information, enhancing a security performance. The disk is divided into a plurality of zones in radial directions. A logical zone count in each zone is obtained by dividing a total recordable frame count in each zone by a frame count in a unit logical zone. For example, a logical zone count N1z in a zone i is given by: N1z=Fzi/F1z where Fzi is the total frame count in the zone i, and F1z is a frame count in the logical zone. However, a value given by the formula (1) is not always an integer depending on the zone, and there might exist a frame (gap region) not used for the logical zone. Accordingly, the security data are recorded in this gap region.