Enteric preparation coated with a non-solvent enteric coating agent using a liquid plasticizer

An enteric preparation prepared by coating a solid dosage form with a fine powder enteric coating agent while spraying a liquid plasticizer.

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Claims

1. A method of preparing an enteric preparation coated with a non-solvent enteric coating agent without drying, said method comprising applying to a solid dosage form a non-solvent coating composition consisting essentially of a fine powder polymeric enteric coating agent while spraying a liquid plasticizer therefor.

2. The method of preparing an enteric preparation coated with a non-solvent enteric coating agent without drying of claim 1, wherein said solid dosage form is granules or parvules of the active ingredient.

3. The method of preparing an enteric preparation coated with a non-solvent enteric coating agent without drying of claim 1, wherein said liquid plasticizer is triethyl citrate.

4. The method of preparing an enteric preparation coated with a non-solvent enteric coating agent without drying of claim 1, wherein the particle diameter of said fine powder polymeric enteric coating agent is 10 micrometers or less.

Referenced Cited
U.S. Patent Documents
2373763 April 1945 Kuever et al.
4462839 July 31, 1984 McGinley et al.
5275824 January 4, 1994 Carli et al.
5430021 July 4, 1995 Rudnic et al.
Patent History
Patent number: 5837291
Type: Grant
Filed: May 31, 1996
Date of Patent: Nov 17, 1998
Assignee: Shin-Etsu Chemical Co., Ltd. (Tokyo)
Inventors: Naosuke Maruyama (Kubiki-Mura), Hiroyasu Kokubo (Kubiki-Mura)
Primary Examiner: Thurman K. Page
Assistant Examiner: James M. Spear
Law Firm: Townsend&Banta
Application Number: 8/657,691