Patents Issued in September 20, 2001
  • Publication number: 20010023205
    Abstract: An entertainment device comprises: an operation device comprising a plurality of push operation mechanisms, each of which outputs a multi-level signal indicating one of three or more values, which change according to the amount of the push operation; a data hold section, which holds an image expression data to display one entertainment image by a different representation style by associating with an identification information of the corresponding representation style and an identification information of said push operation mechanism to which an input is scheduled, and a value of a multi-level signal; a detection section to detect a value of the identification information and the multi-level signal of said push operation mechanism input from said operation device; a data retrieval section, which specifies the identification information of the detected said push operation mechanism and the identification information of said representation style corresponding to the value of the multi-level signal and retrieves
    Type: Application
    Filed: February 22, 2001
    Publication date: September 20, 2001
    Inventors: Hideaki Kikukawa, Hajime Saito
  • Publication number: 20010023206
    Abstract: A coupling has a pair of elastomeric rings centered on a common axis and having generally frustoconical inner faces confronting each other and generally planar outer faces extending generally perpendicular to the axis and directed oppositely away from each other. Respective generally planar, rigid, and annular outer plates centered on the axis are bonded to the outer faces. A metallic center body having frustoconical outer faces bonded to the ring inner faces is formed with a plurality of radially throughgoing center passages.
    Type: Application
    Filed: March 16, 2001
    Publication date: September 20, 2001
    Applicant: CENTA-ANTRIEBE KIRSCHEY GmbH
    Inventor: Gerhard Kirschey
  • Publication number: 20010023207
    Abstract: An elastic coupling for connecting a control element to a component which is to be adjusted by means of the control element, for example a flap-adjusting means of a heating system of a motor vehicle, has two discs which are axially spaced from each other. The disc has at least one radial slot in which the other disc engages with an axially oriented, elastic finger.
    Type: Application
    Filed: February 26, 2001
    Publication date: September 20, 2001
    Applicant: Mannesmann VDO AG
    Inventor: Marcus Zusch
  • Publication number: 20010023208
    Abstract: The present invention provides a golf ball having soft and good shot feel, high rebound characteristics and excellent abrasion resistance when hit by an iron club.
    Type: Application
    Filed: December 28, 2000
    Publication date: September 20, 2001
    Inventor: Satoshi Iwami
  • Publication number: 20010023209
    Abstract: A ball motion measuring apparatus (10) has a CCD camera (11) having a multi-shutter (11b) which can open and close successively; strobes (13-1-13-4); a swinging speed measuring sensor (14); and a controlling/computing device (16) connected to the CCD camera (11), the strobes (13-1-13-4), and the swinging speed measuring sensor (14). The swinging speed measuring sensor (14) outputs a trigger signal for opening/closing the shutter to the CCD camera (11) when the swinging speed measuring sensor (14) detects passage of a golf club. Upon receipt of the trigger signal, the multi-shutter (11b) opens and closes successively. Synchronously with the opening/closing of the multi-shutter (11b), the strobes (13-1-13-4) emit flashlight sequentially. In this manner, a plurality of images of a golf ball (31) driven by the golf club are photographed in a one-image frame.
    Type: Application
    Filed: March 15, 2001
    Publication date: September 20, 2001
    Inventor: Akio Yamamoto
  • Publication number: 20010023210
    Abstract: This invention refers to a novel ballgame racket, especially a tennis racket, including a racket head formed by a tension frame with stringing, and also having a grip portion joining the tension frame, for example by means of a crossing and formed by a gripping shaft or a racket neck and a handle.
    Type: Application
    Filed: March 13, 2001
    Publication date: September 20, 2001
    Inventor: Udo Munster
  • Publication number: 20010023211
    Abstract: A flexible, removable cover for a bicycle drive train including an elongated oval pouch dimensioned and configured to encase the front and rear sprocket and derailleurs, chain, and one pedal of a bicycle, pouch having a central flap folded over the central portion of the chain, VELCRO® patches strategically placed to hold and to secure portions of the cover about the front and rear sprockets, a zipper assembly to secure flap in place, and a wraparound seat post enclosure with a barrel-lock cinch which keeps water and debris from migrating down the post and onto the bicycle drive train. For tandem bicycles, an additional cover is provided for covering the chainstay drivetrain which is configured as an elongated pouch encasing a front and a rear pedal at their respective axles and covering the front and rear drive train sprockets and the intervening drive chain.
    Type: Application
    Filed: April 18, 2001
    Publication date: September 20, 2001
    Inventor: Melinda K. Bowman
  • Publication number: 20010023212
    Abstract: Each link plate of a low noise silent chain has an inside meshing surface formed on the inside flank of each link tooth. The inside meshing surface includes a convexly arcuate mesh start portion disposed on a tip side of each link tooth, and a convexly arcuate mesh guide portion disposed on a root side of each link tooth. The arcuate mesh guide portion has a radius of curvature and a circular arc length which are greater than a radius of curvature and a circular arc length, respectively, of the convexly arcuate mesh start portion. When the silent chain engages a sprocket, the engagement proceeds smoothly and continuously from the inside meshing surface to the outside meshing surface. This contributes to the reduction of the noise level of the silent chain as a whole through suppression of meshing sound of the outside meshing surface and vibratory chain noise.
    Type: Application
    Filed: March 15, 2001
    Publication date: September 20, 2001
    Inventors: Hiroshi Horie, Kazumasa Matsuno, Shigekazu Fukuda, Takayuki Funamoto, Yoshinori Iwasaki, Nobuto Kozakura, Toyonaga Saito
  • Publication number: 20010023213
    Abstract: A silent chain for use with a sprocket has a plurality of interleaved rows of link plates connected together in an endless fashion, each link plate having a pair of teeth. Each of the teeth has an inside flank and an outside flank surface merging at a tip of the tooth. The inside flank has a smooth contact surface which is smaller in width than the smooth contact surface of the outside flank surface. The point where the link plate starts to move into contact with the tooth flank of the sprocket is set to locate in an area having the smooth contact surface at a relatively high rate of occupancy. With this arrangement, noise occurring at the mesh between the link plate and the sprocket can be reduced. The point where the meshing engagement completes is set to locate in an area having the smooth contact surface at a relatively high rate of occupancy. This arrangement improves the wear resistance and fatigue strength of the link plate.
    Type: Application
    Filed: January 12, 2001
    Publication date: September 20, 2001
    Inventors: Hiroshi Horie, Kazumasa Matsuno, Shigekazu Fukuda, Takayuki Funamoto, Yoshinori Iwasaki, Nobuyuki Onoda
  • Publication number: 20010023214
    Abstract: In an automatic transmission for conducting a gear change by replacing friction engagement elements, a transmission torque capacity of an engage side friction engagement element at a torque phase is corrected based upon a change amount per unit time of a turbine rotation speed at the torque phase or a torque phase time.
    Type: Application
    Filed: February 8, 2001
    Publication date: September 20, 2001
    Inventors: Hiroyuki Yuasa, Yoshikazu Tanaka
  • Publication number: 20010023215
    Abstract: A toroidal type continuously variable transmission transmits a torque from an input disk to an output disk through a plurality of groups of rollers interposed between the input disk and the output disk. Respective carriages for the rollers are connected to one another by a connecting member. A hydraulic actuator collectively applies forces against torque transmission reactive forces respectively received by the rollers to the rollers through the connecting member and the corresponding carriages.
    Type: Application
    Filed: March 9, 2001
    Publication date: September 20, 2001
    Inventor: Yasuharu Misada
  • Publication number: 20010023216
    Abstract: The invention proceeds from a control of a transmission which is adjustable continuously with respect to its transmission ratio, for a motor vehicle. The transmission together with a drive unit is mounted in the drive train of the motor vehicle and the drive unit has an adjustable drive torque. The transmission includes a drive end as well as an output end and operative means for establishing a mechanical operative connection between the drive end and the output end. Furthermore, detection means for detecting a slip quantity is provided. The slip quantity represents the slip between the operating means and the drive end and/or output end. Pregivable measures are initiated in response to a pregiven value of the slip quantity. The essence of the invention is that measures as follows are initiated: a drive of a clutch mounted in the drive train; and/or, a change of the transmission ratio; and/or, a change of the output torque of the drive unit.
    Type: Application
    Filed: September 24, 1999
    Publication date: September 20, 2001
    Inventors: MARTIN-PETER BOLZ, HOLGER HULSER
  • Publication number: 20010023217
    Abstract: A transmission mechanism of the continuously variable transmission comprises a set of primary and secondary pulleys between which a belt is provided. The CVT control unit is operable to supply line pressure directly to a secondary pulley and also to a primary pulley via a shift control valve associated with a step motor in such a manner as to control a transmission ratio. The CVT control unit calculates a standard step position of the step motor corresponding to the target transmission ratio and provides a command signal representative of a difference between the standard step position and the current position of the step motor. The shift control valve actuated by the step motor controls the pressure to be supplied to the primary pulley. The actual transmission ratio obtained on the basis of the rotation speeds of the pulleys is compared with the target transmission ratio. If the shift is not accomplished, the CVT control unit commands additional step number.
    Type: Application
    Filed: March 14, 2001
    Publication date: September 20, 2001
    Inventors: Yoshikazu Miyagawa, Satoshi Sakakibara
  • Publication number: 20010023218
    Abstract: The current invention concerns a system of hit detection and signaling for fencing, in particular for the epee, characterized by consisting mainly, for each adversary (5,5′), on one hand, of an outfit (1, 1′, 1″, 1′″) completely conductive surface wise, on the other hand, of a fencing conductive mask (2), eventually endowed with a luminous hit signaling device (3, 3′) and finally of a weapon (4), in particular an epee, comprising a guard (4′) made of an isolating material or covered with an isolating material and whose tip (4″) at least is conductive, the outfit (1,1′,1″,1′″) and the mask (2) on one hand, and the tip of the weapon (4″) at least on the other, for each adversary (5,5′) being connected, separately, to a hit detection unit (6 or 7), appearing as a central detection and signaling unit (6) to which they are wired (8) or as a portable unit (7) carried by each adversary (5,5′) also connected to the luminous sign
    Type: Application
    Filed: March 19, 2001
    Publication date: September 20, 2001
    Applicant: COMPUTER MASTERS INTERNATIONAL
    Inventor: Frederic Marciano
  • Publication number: 20010023219
    Abstract: The exercise device (10) exercises both the upper and lower body in associated motion, while preventing derailment or other related instability of the lower body linkage, due to the connection and force imparted from the upper body linkage. The device includes a frame (12) which has a forward upright member (20). The axle mounts (30) and (32) are attached to the rear region of the frame (12) and support a transverse axle (34) which is preferably operatively connected to a flywheel (36). The ends of the transverse axle (34) rotatably engage left and right crank arm assemblies (40) and (50) that are coupled to the left and right foot links (60) and (70) so that the foot links travel in an arcuate reciprocal path as the transverse axle rotates. The forward ends (62) and (72) of the foot links terminate in rollers (68) and (78), which engage guide tracks (42) and (52) that are mounted to the frame.
    Type: Application
    Filed: May 29, 2001
    Publication date: September 20, 2001
    Applicant: Illinois Tool Works Inc.
    Inventors: Peter Arnold, Philip S. Lamb, Michael Baum, Mark Sand
  • Publication number: 20010023220
    Abstract: A jump rope consisting of an elongated cord extending between a pair of handles. The cord has a pair of end portions connected to the handles, a mid portion and a pair of intermediate portions between the mid portion and the end portions. Each of the intermediate portions has a weight per unit length that is two to four times that of the remaining portions of the cord. More specifically, the length of each intermediate portion is from 10% to 24% of the total length of the cord and the length of each end portion is from 8% to 12% of the total length of the cord. In one embodiment, the extra weight of each intermediate portion is achieved by having the thickness of the intermediate portion greater than the other portions of the cord. In another embodiment, the extra weight of each intermediate section is achieved by having beads strung on the intermediate sections.
    Type: Application
    Filed: February 1, 2001
    Publication date: September 20, 2001
    Inventor: Ronald O. Bouvier
  • Publication number: 20010023221
    Abstract: A highly versatile exercise apparatuses is disclosed. More particularly, the invention relates to a cable crossover exercise apparatus including a central weight stack and opposed extension arms. The invention also relates to a functional lift exercise apparatus including a central weight stack and substantially parallel extension arms. The invention further relates to a cable type exercise apparatus employing a pulley assembly with a 4:1 load ratio.
    Type: Application
    Filed: May 25, 2001
    Publication date: September 20, 2001
    Inventor: Roy Simonson
  • Publication number: 20010023222
    Abstract: A tool exchanging apparatus for a processing center, provided with at least one tool spindle (2), in which a tool (1) can be clamped and which can be moved in the direction of the spindle axis and at least also in a direction vertical to this direction, equipped with a tool magazine (3) and with two tool holding devices (4a) on a transporting device (4) with which the tool holding device (4a) can be moved to a tool exchanging position located in the movement region of the tool spindle (2), wherein one used tool (1) can be deposited from the tool spindle (2) and a new tool can be removed from the tool spindle (2). Each of the tool holding devices (4a), which are provided at least in pairs, is allocated to its own transporting device (4) so that the transporting devices can be moved back and forth independently of each other between the tool exchanging position and a tool receptacle (3a) of the tool magazine (3). The tool receptacles (3a) of the tool magazine (3) are movable in a circulating manner.
    Type: Application
    Filed: January 8, 2001
    Publication date: September 20, 2001
    Inventors: Frank Germerodt, Thorsten Lasch, Eberhard Stenzel
  • Publication number: 20010023223
    Abstract: A roller in the form of a hollow cylinder is for use in harvesting machines and has inner support plates provided within the roller. A plurality of the innermost support plates are connected together by at least one axle section so as to prevent lateral displacement.
    Type: Application
    Filed: February 22, 2000
    Publication date: September 20, 2001
    Inventors: Nicolas Mornet, Benoit Louyot, Martin Hawlas
  • Publication number: 20010023224
    Abstract: A roll has a continuous tubular roll shell (11) of a composite material and axle journals (12) rotating together with the roll shell and joined to each end of the roll shell. The axle journals are supported on a supporting element (13) surrounding the axle journal (12) by at least two bearing elements (14, 15) located at a distance from each other in the axial direction (X-X) of the roll, which supporting element (13) for its part is supported on the machine frame structures (R). The first bearing element (14, 15) is supported on the supporting element (13) through a bending mechanism (20, 21), which is used for applying to the first bearing element (14, 15) a force affecting in a radial direction in order to deflect the first bearing element (14, 15) in relation to the central axis (X-X) of the unbent roll, whereby the axle journal (12) will bend in relation to a pivot point which is formed at the second bearing element (14, 15) and a bending moment is applied to the roll shell (11).
    Type: Application
    Filed: March 9, 2001
    Publication date: September 20, 2001
    Inventors: Juha Isometsa, Tuomo Kurkela, Jorma Snellman
  • Publication number: 20010023225
    Abstract: A developer roll sleeve and method for making the same is disclosed. In a preferred embodiment, a core substrate roll is spray coated with a conductive composition comprising a host resin composition and a wear-resistance imparting additive. Preferably, the host resin composition comprises a phenolic thermosetting resin and a conductivity additive such as carbon black, graphite and the like. Further, the wear resistance imparting additive is preferably selected from the group consisting of a polytetrafluoroethylene resin (e.g., Teflon), graphite, ultra-high molecular weight polyethylene having a molecular weight from about 3,000 to about 4,500 grams, molybdenum, molybdenum disulfide, silicone and mixtures thereof. The wear resistance imparting additive is preferably provided in an amount sufficient to obtain a thickness wear rate of less than about 0.00047 percent per printing cycle.
    Type: Application
    Filed: April 27, 2001
    Publication date: September 20, 2001
    Applicant: Xerox Corporation
    Inventors: Alan M. Litman, Michael F. Zona, Rafael Malespin
  • Publication number: 20010023226
    Abstract: The invention relates to a method for the production of mailing bags, including envelopes, from material in web form, the material being processed in numerous ways and at least two separately prepared parts being transported to a joining station and there joined to one another with the aid of adhesive, the two parts, at least one of which is already provided with the necessary adhesive, being placed one upon the other during an arcuate movement and joined to one another, in order to increase the speed of production.
    Type: Application
    Filed: January 22, 2001
    Publication date: September 20, 2001
    Inventor: Martin Bluemle
  • Publication number: 20010023227
    Abstract: A method for transferring cardboard blanks (7) in individual succession in a plant, comprising a store (1) for collection of cardboard blanks (7b), a conveyor (3), with an upstream portion (3a) which is designed to receive the cardboard blanks (7a), and a rotary collector-translator (2), comprising one or a plurality of orbiting gripper units (100, 200), wherein the cardboard blank is grasped in the store (1), extracted, translated and spaced, whilst being kept substantially parallel to the successive cardboard blank (7c), which is still disposed in the vicinity of the downstream end (1a) of the store (1); and is then inclined, and placed parallel on the upstream portion (3a) of the conveyor (3). A corresponding system, and a corresponding rotary collector-translator.
    Type: Application
    Filed: March 14, 2001
    Publication date: September 20, 2001
    Applicant: BAUMER S.r.l.
    Inventor: Mario Gambetti
  • Publication number: 20010023228
    Abstract: In a method for working an elongate web of material, use is made of a machine which comprises a feeding device for feeding the web at a given speed and a cutting device for making cuts in the web. The cutting device comprises a rotary backing roll and a rotary cutting roll with a projecting cutting means. The cutting roll is adapted to move, during a first part of its revolution, the cutting means into engagement with the backing roll to form the cuts in the web and, during a second part of its revolution, define with the backing roll a gap through which the web moves essentially unimpededly. A control means is adapted to control, preferably in an infinitely variable manner, the speed of rotation of the cutting roll relative to the speed of the web during the second part of the revolution for optional adjustment of the distance between succeeding cuts in the web.
    Type: Application
    Filed: March 16, 2001
    Publication date: September 20, 2001
    Inventor: Thomas Leijon
  • Publication number: 20010023229
    Abstract: A desk-top centrifuge is provided which includes a switching element disposed between a dc power supply and a motor and a controlling circuit. The controlling circuit receives a voltage of power regenerated by the motor to provide a pulse width-controlled on-off signal to the drive switching element to control speed of the motor. The controlling circuit increases an on-duration in which the on-off signal is at an on-level at a given rate to turns the motor slowly. The centrifuge has a safety guard system made up of a door switch and a door lock switch which are installed in series between the dc power supply and the motor and work to establish electric communication between the dc power supply and the motor when the door is closed and locked.
    Type: Application
    Filed: March 15, 2001
    Publication date: September 20, 2001
    Inventors: Masahiro Inaniwa, Masanori Yoshioka, Tsutomu Takamura, Masaharu Aizawa, Kouiti Akatsu
  • Publication number: 20010023230
    Abstract: A CRT in its entirety is to be rendered lightweight without detracting from the resistance against pressure of a panel or from characteristics desirable for the CRT. To this end, there is provided a glass panel for a CRT obtained on chemically reinforcing the glass containing 57 to 64 wt % of SiO2, 0.1 to 4 wt % of Al2O3, 5 to 10 wt % of Na2O, 5 to 10 wt % of K2O, 7 to 13 wt % of SrO, 7 to 11 wt % of BaO, 0.1 to 2 wt % of TiO2, 0.1 to 4 wt % of ZrO2 and 0.01 to 1 wt % of CeO2.
    Type: Application
    Filed: February 9, 2001
    Publication date: September 20, 2001
    Inventors: Masataka Santoku, Fumio Kuramoto, Masamichi Okada, Yoichi Hachitani, Itaru Watanabe
  • Publication number: 20010023231
    Abstract: The present invention relates to components of catalysts for the polymerization of olefins comprising a metallocene compound and a magnesium halide which have particular values of porosity and surface area. In particular the components of the invention have surface area (BET) greater than about 50 m2/g, porosity (BET) greater than about 0.15 cm3/g and porosity (Hg) greater than 0.3 cm3/g, with the proviso that when the surface area is less than about 150 m2/g, the porosity (Hg) is less than about 1.5 cm3/g. The components of the invention are particularly suitable for the preparation of catalysts for the gas-phase polymerization of &agr;-olefins.
    Type: Application
    Filed: September 10, 1997
    Publication date: September 20, 2001
    Inventors: MARIO SACCHETTI, STEFANO PASQUALI, GABRIELE GOVONI
  • Publication number: 20010023232
    Abstract: An oxygen-absorbing composition containing particulate annealed electrolytically reduced iron of between about 100 mesh and 325 mesh in an amount of about up to 63% by weight, a salt such as sodium chloride in an amount by weight of about up to 3.5%, and a water-supplying component comprising activated carbon with liquid water therein of a mesh size of between about 20 mesh and 50 mesh in an amount by weight of up to about 85% in an envelope which will resist the passage of liquid water out of the envelope but will permit flow of oxygen into the envelope at a satisfactory rate.
    Type: Application
    Filed: May 2, 2001
    Publication date: September 20, 2001
    Inventor: George E. McKedy
  • Publication number: 20010023233
    Abstract: This invention relates to highly purified biogenic silica product obtained from diatomite and methods for preparing same. More particularly, this invention pertains to highly purified non-calcined, calcined, and flux-calcined diatomite products which bear the distinguishing porous and intricate structure of silica unique to diatomite and which have an extraordinarily high silica (i.e., silicon dioxide, SiO2) content and low density, resulting in high silica specific volume. These products often also exhibit exceptionally low soluble metals content and/or extreme brightness.
    Type: Application
    Filed: May 2, 2001
    Publication date: September 20, 2001
    Inventors: Jerome C. Shiuh, Scott K. Palm, Timothy R. Smith, George A. Nyamekye, Jeffrey D. Taniguchi, Qun Wang
  • Publication number: 20010023234
    Abstract: A reactor for coating flat substrates and particularly wafers is described which has
    Type: Application
    Filed: May 30, 2001
    Publication date: September 20, 2001
    Inventors: Holger Jurgensen, Karl Heinz Bachem
  • Publication number: 20010023235
    Abstract: This invention relates to a method for thermal conditioning of hair which comprises:
    Type: Application
    Filed: November 30, 2000
    Publication date: September 20, 2001
    Inventors: Joanne Crudele, Wolfgang Bergmann, Kimberly Kamis, Pawel Milczarek, Varsha Shah
  • Publication number: 20010023236
    Abstract: A bleaching composition is provided comprising
    Type: Application
    Filed: December 20, 2000
    Publication date: September 20, 2001
    Inventors: Dirk Johannes Bijl, Ronald Hage, Jan Kevelam, Jean Hypolites Koek, Dennis Stephen Murphy, Irene Erica Smit, Johannes Jacob Verhagen, Pieter Van Der Vlist
  • Publication number: 20010023237
    Abstract: A bleaching composition is provided comprising
    Type: Application
    Filed: December 20, 2000
    Publication date: September 20, 2001
    Inventors: Dirk Johannes Bijl, Ronald Hage, Jan Kevelam, Jean Hypolites Koek, Dennis Stephen Murphy, Irene Erica Smit, Johannes Jacob Verhagen, Pieter Van Der Vlist
  • Publication number: 20010023238
    Abstract: A process for preventing the redeposition of migrant dyes in a washing liquor by adding to each liter of the washing liquor, which comprises a peroxide-containing detergent, from 0.5 to 150 mg of one or more asymmetric manganese complexes of the salen type.
    Type: Application
    Filed: April 13, 2001
    Publication date: September 20, 2001
    Inventors: Frank Bachmann, Josef Dannacher, Cornelia Makowka, Gunther Schlingloff, Peter Weingartner, Grit Richter
  • Publication number: 20010023239
    Abstract: Solid block alkaline detergent compositions are disclosed comprising a source of alkalinity, and other detergent additives including sequestrants. The solid block detergents of the invention used a mixed inorganic and organic sequestrant composition that successfully softens service water used in manufacturing aqueous detergents from the composition, but also obtains substantially improved organic soil removal on dishware or flatware. The solid block detergents of the invention comprise large masses of the chemical ingredients having a weight of greater than about 500 grams in a solid block product format that is typically dispensed using a spray on water dispenser that creates an aqueous concentrate that is used in a washing machine.
    Type: Application
    Filed: March 15, 2001
    Publication date: September 20, 2001
    Applicant: Ecolab Inc.
    Inventors: Steven E. Lentsch, Keith E. Olson
  • Publication number: 20010023240
    Abstract: Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides, such as rhGH. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration, are provided, and methods of preparation of the modified amino acid compound are provided.
    Type: Application
    Filed: May 5, 1999
    Publication date: September 20, 2001
    Inventors: ANDREA LEONE-BAY, KOC-KAN HO, DONALD J. SARUBBI, SAM J. MILSTEIN, NAI FANG WANG
  • Publication number: 20010023241
    Abstract: Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.
    Type: Application
    Filed: February 2, 2001
    Publication date: September 20, 2001
    Inventors: Mark X. Sliwkowski, Jeffrey A. Kern
  • Publication number: 20010023242
    Abstract: The present invention relates to an anti-tumor agent comprising Salmosin which is a novel disintegrin containing Arg-Gly-Asp(RGD) sequence and derived from venom of Korean snake, Agkistrodon halys brevicaudus, as an active ingredient. Salmosin is a disintegrin which blocks the function of &agr;v&bgr;3 integrin and strongly inhibits tumor angiogenesis, tumor metastasis as well as growth of solid tumor. Salmosin does not exhibit cytotoxicity within an effective dose range where tumor growth is efficiently suppressed without any untoward effect on preexisting blood vessels and normal angiogenesis. Accordingly, Salmosin can be applied for the development of potent anti-tumor drugs which are effective for various types of cancers.
    Type: Application
    Filed: February 1, 2001
    Publication date: September 20, 2001
    Applicant: Doo-Sik KIM
    Inventors: Doo-Sik Kim, Kwang Hoe Chung, In-Cheol Kang
  • Publication number: 20010023243
    Abstract: A method for treating hypoparathyroidism and/or hypocalcemia by local administration of a neurotoxin, such as a botulinum toxin, to a parathyroid gland, thereby reducing an inhibitory effect upon parathyroid hormone secretion. A method for treating hyperparathyroidism and/or hypercalcemia by local administration of a neurotoxin, such as a botulinum toxin, to a sympathetic ganglion which innervates a parathyroid hormone secreting parathyroid cell, thereby reducing a stimulatory effect upon parathyroid hormone secretion.
    Type: Application
    Filed: April 16, 2001
    Publication date: September 20, 2001
    Applicant: Allergan Sales, Inc.
    Inventor: Stephen Donovan
  • Publication number: 20010023244
    Abstract: There is provided EtO2C—CH2—(R)Cgl—Aze—Pab—OH, or a pharmaceutically-acceptable salt thereof, in a form which is substantially crystalline. It has been found that crystalline forms of EtO2C—CH2—(R)Cgl—Aze—Pab—OH have a high chemical and solid state stability when compared to amorphous forms of the compound.
    Type: Application
    Filed: January 4, 2001
    Publication date: September 20, 2001
    Applicant: Astra Aktiebolag
    Inventors: Daniel Edvardsson, Lena Hedstrom, Anita Lundblad, Ursula Pettersson
  • Publication number: 20010023245
    Abstract: According to the present invention, an ophthalmic composition which comprises a neurotrophic factor, an optic nerve functional disorder-treating agent which comprises a neurotrophic factor, and a method for treating an optic nerve functional disorder, which comprises administering an effective amount of a neurotrophic factor, particularly a glaucoma-treating agent and a method for treating the same are provided.
    Type: Application
    Filed: May 23, 2001
    Publication date: September 20, 2001
    Applicant: ADVANCED MEDICINE RESEARCH INSTITUTE
    Inventor: Shinseiro Okamoto
  • Publication number: 20010023246
    Abstract: Use of at least one polymer or one biopolymer called HBGFPP, specifically protecting the growth factors of FGFs and beta TGFs families from tryptic degradation in the manufacture of a drug for the treatment of lesions of the nervous system.
    Type: Application
    Filed: November 30, 2000
    Publication date: September 20, 2001
    Inventors: Denis Barritault, Jean-Pierre Caruelle, Ahmed Aamiri, Jean Gautron
  • Publication number: 20010023247
    Abstract: Photodynamic therapy of conditions of the eye characterized by unwanted neovasculature, such as age-related macular degeneration, is effective using green porphyrins as photoactive agents, preferably as liposomal compositions.
    Type: Application
    Filed: April 2, 2001
    Publication date: September 20, 2001
    Inventors: Joan W. Miller, Evangelos S. Gragoudas
  • Publication number: 20010023248
    Abstract: The present invention relates to novel aminomethylene substituted non-aromatic heterocycles and, specifically, to compounds of the formula 1
    Type: Application
    Filed: February 7, 2001
    Publication date: September 20, 2001
    Inventors: Harry R. Howard, Brian T. O'Neill
  • Publication number: 20010023249
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below.
    Type: Application
    Filed: January 25, 2001
    Publication date: September 20, 2001
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder
  • Publication number: 20010023250
    Abstract: This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor or p56lck tyrosine kinase activity, to pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.
    Type: Application
    Filed: April 6, 2001
    Publication date: September 20, 2001
    Inventors: Alfred P. Spada, Wei He, Michael R. Myers
  • Publication number: 20010023251
    Abstract: The invention concerns new guanidine derivatives of formula (I), methods of preparing them and their use in drugs containing such compounds.
    Type: Application
    Filed: March 23, 2001
    Publication date: September 20, 2001
    Inventors: Eberhard Amtmann, Norbert Frank, Gerhard Sauer, Gerhard Schilling
  • Publication number: 20010023252
    Abstract: Invented are pharmaceutical compositions containing paroxetine methanesulfonate.
    Type: Application
    Filed: March 12, 2001
    Publication date: September 20, 2001
    Applicant: SmithKline Beecham Plc
    Inventors: Ahmad Khalaf Al-Deeb Al-Ghazawi, Andrew Simon Craig, David Philip Elder, Victor Witold Jacewicz, David Alan Jones, Deirdre O'Keeffe, Padma Meneaud Patel, Michael Urquhart, Neal Ward
  • Publication number: 20010023253
    Abstract: Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
    Type: Application
    Filed: March 14, 2001
    Publication date: September 20, 2001
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Andrew Simon Craig, Victor Witold Jacewicz, Michael Urquhart
  • Publication number: 20010023254
    Abstract: Impulse Control Disorders (ICD's) are characterized by harmful behaviors performed in response to irresistible impulses. The essential feature of an ICD is the failure to resist an impulse, drive, or temptation and to perform an act that is harmful to the person or to others.
    Type: Application
    Filed: February 18, 2000
    Publication date: September 20, 2001
    Inventor: Susan L. McElroy